Hudson Institute - Department of Molecular and Translational Science

Research Output

2016

Impaired cellular bioenergetics causes mitochondrial calcium handling defects in MT-ND5 mutant cybrids

McKenzie, M. & Duchen, M. R., 1 Apr 2016, In : PLoS ONE. 11, 4, 12 p., e0154371.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Incomplete target neutralization by the anti-cancer antibody rilotumumab

Greenall, S. A., Adams, T. E. & Johns, T. G., 1 Jan 2016, In : mAbs. 8, 2, p. 246-252 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Inflammation, dysregulated metabolism and aromatase in obesity and breast cancer

Zahid, H., Simpson, E. R. & Brown, K. A., 1 Dec 2016, In : Current Opinion in Pharmacology. 31, p. 90-96 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

24 Citations (Scopus)

Inhibition of JAK-STAT ERK/MAPK and glycogen synthase kinase-3 induces a change in gene expression profile of bovineInduced pluripotent stem cells

Malaver-Ortega, L., Sumer, H., Liu, J. & Verma, P. J., 2016, In : Stem Cells International. 2016, 11 p., 5127984.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Integration of Palliative Care for Patients with Metastatic Breast Cancer: Have We Achieved Quality End-of-Life Care?

Philip, J., Collins, A., Burchell, J., Krishnasamy, M., Mileshkin, L., McLachlan, S-A., Le, B., Millar, J. L., Currow, D., Hudson, P. & Sundararajan, V., 1 Dec 2016, p. e152. 1 p.

Research output: Contribution to conferenceAbstract

Interferon-γ promotes gastric lymphoid follicle formation but not gastritis in Helicobacter-infected BALB/c mice

Chonwerawong, M., Avé, P., Huerre, M. & Ferrero, R. L., 21 Nov 2016, In : Gut Pathogens. 8, 1, p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

In the shadow of fibrosis: Innate immune suppression mediated by transforming growth factor-β

Thomas, B. J., Kan-o, K., Loveland, K., Elias, J. A. & Bardin, P. G., 1 Dec 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 6, p. 759-766 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

18 Citations (Scopus)

In Utero Nutritional Manipulation Provokes Dysregulated Adipocytokines Production in F1 Offspring in Rats

Hanafi, M. Y., Saad, M. I., Abdelkhalek, T. M., Saleh, M. M. & Kamel, M. A., 1 Jan 2016, In : Scientifica. 2016, 10 p., 3892890.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Loss of gastrokine-2 drives premalignant gastric inflammation and tumor progression

Menheniott, T. R., O'Connor, L., Chionh, Y. T., Däbritz, J., Scurr, M., Rollo, B. N., Ng, G. Z., Jacobs, S., Catubig, A., Kurklu, B., Mercer, S., Minamoto, T., Ong, D. E., Ferrero, R. L., Fox, J. G., Wang, T. C., Sutton, P., Judd, L. & Giraud, A. S., 1 Apr 2016, In : Journal of Clinical Investigation. 126, 4, p. 1383-1400 18 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly

Lim, C., Hroudová, J., Van Bergen, N. J., Lopez Sanchez, M. I. G., Trounce, I. A. & McKenzie, M., 1 Jun 2016, In : The FASEB Journal. 30, 6, p. 2236-2248 13 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Low-dose histone deacetylase inhibitor treatment leads to tumor growth arrest and multi-lineage differentiation of malignant rhabdoid tumors

Muscat, A., Popovski, D., Jayasekara, W. S. N., Rossello, F. J., Ferguson, M., Marini, K. D., Alamgeer, M., Algar, E. M., Downie, P., Watkins, D. N., Cain, J. E. & Ashley, D., 15 Jul 2016, In : Clinical Cancer Research. 22, 14, p. 3560-3570 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

Lung ultrasound accurately detects pneumothorax in a preterm newborn lamb model

Blank, D. A., Hooper, S. B., Binder-Heschl, C., Kluckow, M., Gill, A. W., LaRosa, D. A., Inocencio, I. M., Moxham, A., Rodgers, K., Zahra, V. A., Davis, P. G. & Polglase, G. R., 1 Jun 2016, In : Journal of Paediatrics and Child Health. 52, 6, p. 643-648 6 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Mapping the testicular interstitial fluid proteome from normal rats

Stanton, P. G., Foo, C. FH., Rainczuk, A., Stephens, A. N., Condina, M., O'Donnell, L., Weidner, W., Ishikawa, T., Cruickshanks, L., Smith, L. B. & McLachlan, R. I., 1 Sep 2016, In : Proteomics. 16, 17, p. 2391-2402 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Measuring PC activity in endocervical swab may provide a simple and non-invasive method to detect endometrial cancer in post-menopausal women

Heng, S., Stephens, A. N., Jobling, T. W. & Nie, G., 25 Jun 2016, In : Oncotarget. 7, 29, p. 46573-46578 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
4 Citations (Scopus)

microRNA Decay: Refining microRNA Regulatory Activity

Pepin, G. & Gantier, M. P., 2016, In : Microrna. 5, 3, p. 167-174 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

6 Citations (Scopus)

Mitochondrial DNA as an initiator of tumorigenesis

Lee, W. T. Y. & St. John, J. C., 31 Mar 2016, In : Cell Death and Disease. 7, p. e2171 2 p., e2171.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
File
4 Citations (Scopus)

Mitochondrial DNA copy number and replication in reprogramming and differentiation

St. John, J. C., 1 Apr 2016, In : Seminars in Cell and Developmental Biology. 52, p. 93-101 9 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

25 Citations (Scopus)

Mitochondrial DNA plasticity is an essential inducer of tumorigenesis

Lee, WTY., Cain, JE., Cuddihy, AR., Johnson, J., Dickinson, A., Yeung, K-Y., Kumar, B., Johns, TG., Watkins, DN., Spencer, A. & St John, JC., 2016, In : Cell Death Discovery. 2, p. 1 - 11 11 p., 16016.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
14 Citations (Scopus)

Mitochondrial DNA supplementation as an enhancer of female reproductive capacity

St John, J. C., Tsai, T-S. & Cagnone, G. L. M., 2016, In : Current Opinion in Obstetrics and Gynecology. 28, 3, p. 211 - 216 6 p.

Research output: Contribution to journalArticleOtherpeer-review

4 Citations (Scopus)

Mitochondrial STAT3: Powering up a potent factor

Garama, D. J., White, C. L., Balic, J. J. & Gough, D. J., 1 Nov 2016, In : Cytokine. 87, p. 20-25 6 p.

Research output: Contribution to journalArticleOther

21 Citations (Scopus)

mTOR inhibition beyond rapalogs

Markman, B., Serra, V. & Tabernero, J., 2016, mTOR Inhibition for Cancer Therapy: Past, Present and Future. Mita, M., Mita, A. & Rowinsky, E. K. (eds.). Paris France: Springer, p. 251 - 27 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Multifaceted Role of IRAK-M in the Promotion of Colon Carcinogenesis via Barrier Dysfunction and STAT3 Oncoprotein Stabilization in Tumors

Jenkins, B. J., 9 May 2016, In : Cancer Cell. 29, 5, p. 615-617 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

3 Citations (Scopus)

Murine oncostatin m acts via leukemia inhibitory factor receptor to phosphorylate signal transducer and activator of transcription 3 (STAT3) but not STAT1, an effect that protects bone mass

Walker, E. C., Johnson, R. W., Hu, Y., Brennan, H. J., Poulton, I. J., Zhang, J. G., Jenkins, B. J., Smyth, G. K., Nicola, N. A. & Sims, N. A., 7 Oct 2016, In : Journal of Biological Chemistry. 291, 41, p. 21703-21716 14 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Myeloid differentiation factor 88 signaling in bone marrow-derived cells promotes gastric tumorigenesis by generation of inflammatory microenvironment

Maeda, Y., Echizen, K., Oshima, H., Yu, L., Sakulsak, N., Hirose, O., Yamada, Y., Taniguchi, T., Jenkins, B. J., Saya, H. & Oshima, M., 1 Mar 2016, In : Cancer Prevention Research. 9, 3, p. 253-263 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
18 Citations (Scopus)

New Interferons

Hertzog, P. J., Bourke, N. M., De Weerd, N. A. & Mangan, N. E., 27 Apr 2016, Encyclopedia of Immunobiology: Molecular Immunology. Radcliffe, M. J. H. (ed.). Oxford UK: Elsevier, Vol. 2. p. 501-508 8 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

1 Citation (Scopus)

Normalization of affymetrix miRNA microarrays for the analysis of cancer samples

Wu, D. & Gantier, M. P., 1 May 2016, Microarray Data Analysis: Methods and Applications. Guzzi, P. H. (ed.). 2nd ed. Humana Press, Vol. 1375. p. 1-10 10 p. (Methods in Molecular Biology; vol. 1375).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

Novel strategies for molecular targeting to cancer

Liu, J. P., 1 Mar 2016, In : Clinical and Experimental Pharmacology and Physiology. 43, 3, p. 287-289 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

Optimizing lung aeration at birth using a sustained inflation and positive pressure ventilation in preterm rabbits

Te Pas, A. B., Kitchen, M. J., Lee, K., Wallace, M. J., Fouras, A., Lewis, R. A., Yagi, N., Uesugi, K. & Hooper, S. B., 1 Jul 2016, In : Pediatric Research. 80, 1, p. 85-91 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

PKR

Sadler, A. J., 12 Dec 2016, Encyclopedia of Signaling Molecules. Choi, S. (ed.). 2 ed. New York: Springer, 9 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

Pluripotent stem cells progressing to the clinic

Trounson, A. & DeWitt, N. D., 1 Mar 2016, In : Nature Reviews Molecular Cell Biology. 17, 3, p. 194-200 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

192 Citations (Scopus)

Potential strategies to ameliorate risk of radiotherapy-induced second malignant neoplasms

Martin, O. A., Yin, X., Forrester, H. B., Sprung, C. N. & Martin, R. F., 1 Jun 2016, In : Seminars in Cancer Biology. 37-38, p. 65-76 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

15 Citations (Scopus)

Prepubertal Di-n-Butyl phthalate exposure alters Sertoli and Leydig cell function and lowers bone density in adult male mice

Bielanowicz, A., Johnson, R. W., Goh, H., Moody, S. C., Poulton, I. J., Croce, N., Loveland, K. L., Hedger, M. P., Sims, N. A. & Itman, C., Jul 2016, In : Endocrinology. 157, 7, p. 2595-2603 9 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Reassessing the role of the NLRP3 inflammasome during pathogenic influenza A virus infection via temporal inhibition

Tate, M. D., Ong, J. DH., Dowling, J. K., McAuley, J. L., Robertson, A. B., Latz, E., Drummond, G. R., Cooper, M. A., Hertzog, P. J. & Mansell, A., 10 Jun 2016, In : Scientific Reports. 6, 8 p., 27912.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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53 Citations (Scopus)

Reconstitution of degenerated ovine lumbar discs by STRO-3-positive allogeneic mesenchymal precursor cells combined with pentosan polysulfate

Oehme, D., Ghosh, P., Goldschlager, T., Itescu, S., Shimon, S., Wu, J., McDonald, C., Troupis, J. M., Rosenfeld, J. V. & Jenkin, G., 1 May 2016, In : Journal of Neurosurgery: Spine. 24, 5, p. 715-726 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Regulation of the blood-testis barrier

Stanton, P. G., 1 Nov 2016, In : Seminars in Cell and Developmental Biology. 59, p. 166-173 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

59 Citations (Scopus)

Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency

Cagnone, G., Tsai, T-S., Makanji, Y., Matthews, P. M., Gould, J. A., Bonkowski, M. S., Elgass, K., Wong, A. S. A., Wu, L. E., McKenzie, M., Sinclair, D. A. & St John, J. C., 2016, In : Scientific Reports. 6, p. 1 - 15 15 p., 23229.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
36 Citations (Scopus)

Segregation of naturally occurring mitochondrial DNA variants in a mini-pig model

Cagnone, G., Tsai, T-S., Srirattana, K., Rossello, F., Powell, D. R., Rohrer, G., Cree, L., Trounce, I. A. & St John, J. C., Mar 2016, In : Genetics. 202, 3, p. 931-944 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
13 Citations (Scopus)

Serum levels of GDF15 are reduced in preeclampsia and the reduction is more profound in late-onset than early-onset cases

Chen, Q., Wang, Y., Zhao, M., Hyett, J., da Silva Costa, F. & Nie, G., 1 Jul 2016, In : Cytokine. 83, p. 226-230 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Severity and timing: How prenatal stress exposure affects glial developmental, emotional behavioural and plasma neurosteroid responses in guinea pig offspring

Bennett, G. A., Palliser, H. K., Walker, D. & Hirst, J., 1 Aug 2016, In : Psychoneuroendocrinology. 70, p. 47-57 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Single sustained inflation followed by ventilation leads to rapid cardiorespiratory recovery but causes cerebral vascular leakage in asphyxiated near-term lambs

Sobotka, K., Hooper, S. B., Crossley, K. J., Ong, T. S. L., Schmolzer, G. M., Barton, S. K., McDougall, A. RA., Miller, S. L., Tolcos, M., Klingenberg, C. & Polglase, G., 1 Jan 2016, In : PLoS ONE. 11, 1, 14 p., 0146574.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

Smad7 gene delivery prevents muscle wasting associated with cancer cachexia in mice

Winbanks, C. E., Murphy, K. T., Bernardo, B. C., Qian, H., Liu, Y., Sepulveda, P. V., Beyer, C., Hagg, A., Thomson, R. E., Chen, J. L., Walton, K. L., Loveland, K. L., McMullen, J. R., Rodgers, B. D., Harrison, C. A., Lynch, G. S. & Gregorevic, P., 20 Jul 2016, In : Science Translational Medicine. 8, 348, 12 p., 348ra98.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Spermatogenesis

de Kretser, D. M., Loveland, K. & O'Bryan, M., 2016, Endocrinology: Adult and Pediatric. Jameson, J. L., De Groot, L. J., de Kretser, D. M., Giudice, L. C., Grossman, A. B., Melmed, S., Potts Jr., J. T. & Weir, G. C. (eds.). 7th ed. Philadelphia, USA: Elsevier, Vol. 2. p. 2325-2353.e9 38 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

4 Citations (Scopus)

Subfascial endoscopic perforator surgery (SEPS) for treating and preventing recurrence of venous leg ulcers (Protocol)

Lin, Z. C., Loveland, P. M., Johnston, R. V., Bruce, M. & Weller, C., 26 Apr 2016, In : Cochrane Database of Systematic Reviews. 2016, 4, p. 1 - 14 14 p., CD012164.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Surgical margins in head and neck squamous cell carcinoma: Effect of heat artifact on immunohistochemistry as a future tool for assessment

Sigston, E. A. W., Longano, A., Strzelecki, A. T. & Williams, B. R. G., Sep 2016, In : Head & Neck. 38, 9, p. 1401-1406 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Targeting interleukin-11 receptor-α impairs human Endometrial cancer cell proliferation and invasion in vitro and reduces tumor growth and metastasis in vivo

Winship, A. L., Van Sinderen, M., Donoghue, J., Rainczuk, K. & Dimitriadis, E., Apr 2016, In : Molecular Cancer Therapeutics. 15, 4, p. 720-730 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
16 Citations (Scopus)

The establishment of DOHaD working groups in Australia and New Zealand

Prescott, S. L., Allen, K., Armstrong, K., Collins, C., Dickinson, H., Gardiner, K. J., Jacka, F. N., Jasoni, C., Moore, T., Moritz, K. M., Muhlhausler, B. S., Siero, W., Sim, K., Nanan, R., Saffery, R., Singh, G., Vickers, M. H. & Craig, J. M., 1 Oct 2016, In : Journal of Developmental Origins of Health and Disease. 7, 5, p. 433-439 7 p.

Research output: Contribution to journalArticleOtherpeer-review

5 Citations (Scopus)

The JAK/STAT pathway in obesity and diabetes

Gurzov, E. N., Stanley, W. J., Pappas, E. G., Thomas, H. E. & Gough, D. J., 1 Aug 2016, In : FEBS Journal. p. 3002-3015 14 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

41 Citations (Scopus)

The kinase activity of PKR represses inflammasome activity

Yim, H. C. H., Wang, D., Yu, L., White, C. L., Faber, P. W., Williams, B. R. G. & Sadler, A. J., 1 Mar 2016, In : Cell Research. 26, 3, p. 367-379 13 p.

Research output: Contribution to journalArticleResearchpeer-review

File
15 Citations (Scopus)

The microenvironment of human implantation: Determinant of reproductive success

Salamonsen, L. A., Evans, J., Nguyen, H. P. T. & Edgell, T. A., Apr 2016, In : American Journal of Reproductive Immunology. 75, 3, p. 218-225 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

61 Citations (Scopus)