Hudson Institute - Department of Molecular and Translational Science

Research Output

2016

Assessing the inhibitory activity of oligonucleotides on TLR7 sensing

Ferrand, J. & Gantier, M. P., 1 Jan 2016, Toll-Like Receptors: Practice and Methods. McCoy, C. E. (ed.). 2nd ed. New York NY USA: Humana Press, p. 79-90 12 p. (Methods in Molecular Biology: Springer Protocols; no. 1390).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

5 Citations (Scopus)

Axitinib has antiangiogenic and antitumorigenic activity in myxoid liposarcoma

Kerr, L. T., Donoghue, J. F., Wilding, A. L. & Johns, T. G., 2016, In : Sarcoma. 2016, 17 p., 3484673.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Bacterial membrane vesicles: Biogenesis, immune regulation and pathogenesis

Pathirana, R. D. & Kaparakis-Liaskos, M., 1 Nov 2016, In : Cellular Microbiology. 18, 11, p. 1518-1524 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

39 Citations (Scopus)

BCL2-modifying factor promotes germ cell loss during murine oogenesis

Vaithiyanathan, K., Liew, S. H., Zerafa, N., Gamage, T., Cook, M., O'Reilly, L. A., Bouillet, P., Scott, C. L., Strasser, A., Findlay, J. K. & Hutt, K. J., 1 May 2016, In : Reproduction. 151, 5, p. 553-562 10 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Biological activity and in vivo half-life of pro-activin A in male rats

Johnson, K. E., Makanji, Y., Temple-Smith, P., Kelly, E. K., Barton, P. A., Al-Musawi, S. L., Mueller, T. D., Walton, K. L. & Harrison, C. A., 15 Feb 2016, In : Molecular and Cellular Endocrinology. 422, p. 84 - 92 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Bone disease in thalassemia: A molecular and clinical overview

Wong, P., Fuller, P. J., Gillespie, M. & Milat, F., Aug 2016, In : Endocrine Reviews. 37, 4, p. 320 - 346 27 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Bone morphogenetic protein 4 and retinoic acid trigger bovine VASA homolog expression in differentiating bovine induced pluripotent stem cells

Malaver-Ortega, L. F., Sumer, H., Jain, K. & Verma, P. J., Feb 2016, In : Molecular Reproduction and Development. 83, 2, p. 149 - 161 13 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Clinical use of GLP-1 agonists and DPP4 inhibitors

Tuch, B. E., 2016, In : Pancreatology. 16, 1, p. 8-9 2 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

4 Citations (Scopus)

Combined defects in oxidative phosphorylation and fatty acid β-oxidation in Mitochondrial disease

Nsiah-Sefaa, A. & McKenzie, M., 1 Apr 2016, In : Bioscience Reports. 36, 2, 9 p., e00313.

Research output: Contribution to journalArticleOtherpeer-review

26 Citations (Scopus)

Control theory prediction of resolved Cheyne-Stokes respiration in heart failure

Sands, S. A., Edwards, B. A., Kee, K., Stuart-Andrews, C., Skuza, E. M., Roebuck, T., Turton, A., Hamilton, G. S., Naughton, M. T. & Berger, P. J., 1 Nov 2016, In : European Respiratory Journal. 48, 5, p. 1351-1359 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Creb1 regulates late stage mammalian lung development via respiratory epithelial and mesenchymal-independent mechanisms

Antony, N., McDougall, A. R., Mantamadiotis, T., Cole, T. J. & Bird, A. D., 6 May 2016, In : Scientific Reports. 6, 12 p., 25569.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Cre-dependent DNA recombination activates a STING-dependent innate immune response

Pépin, G., Ferrand, J., Höning, K., Jayasekara, W. S. N., Cain, J. E., Behlke, M. A., Gough, D. J., Williams, B. R. G., Hornung, V. & Gantier, M. P., 20 Jun 2016, In : Nucleic Acids Research. 44, 11, p. 5356-5364 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation

Browne, H. P., Forster, S., Anonye, B. O., Kumar, N., Neville, B. A., Stares, M. D., Goulding, D. & Lawley, T. D., 4 May 2016, In : Nature. 533, 7604, p. 543-546 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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355 Citations (Scopus)

Dataset of TWIST1-regulated genes in the cranial mesoderm and a transcriptome comparison of cranial mesoderm and cranial neural crest

Bildsoe, H., Fan, X., Wilkie, E. E., Ashoti, A., Jones, V. J., Power, M., Qin, J., Wang, J., Tam, P. P. L. & Loebel, D. A. F., 1 Dec 2016, In : Data in Brief. 9, p. 372-375 4 p.

Research output: Contribution to journalArticleOtherpeer-review

Open Access

Deletion of Rac1GTPase in the myeloid lineage protects against inflammation-mediated kidney injury in Mice

Nagase, M., Kurihara, H., Aiba, A., Young, M. & Sakai, T., 3 Mar 2016, In : PLoS ONE. 11, 3, p. 1-17 17 p., e150886.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)

Deletion of the Complex I subunit NDUFS4 adversely modulates cellular differentiation

Johnson, J., Lee, W., Frazier, A. E., Vaghjiani, V., Laskowski, A., Rodriguez, A. L., Cagnone, G. L., McKenzie, M., White, S. J., Nisbet, D. R., Thorburn, D. R. & St. John, J. C., 2016, In : Stem Cells and Development. 25, 3, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Developmental origins of male subfertility: role of infection, inflammation, and environmental factors

Schagdarsurengin, U., Western, P., Steger, K. & Meinhardt, A., 1 Nov 2016, In : Seminars in Immunopathology. 38, 6, p. 765-781 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

12 Citations (Scopus)

Differential effects of IL6 and activin A in the development of cancer-associated cachexia

Chen, J. L., Walton, K. L., Qian, H., Colgan, T. D., Hagg, A., Watt, M. J., Harrison, C. A. & Gregorevic, P., 15 Sep 2016, In : Cancer Research. 76, 18, p. 5372-5382 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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20 Citations (Scopus)

Disorders of sex development: Insights from targeted gene sequencing of a large international patient cohort

Eggers, S., Sadedin, S., van den Bergen, J. A., Robevska, G., Ohnesorg, T., Hewitt, J., Lambeth, L., Bouty, A., Knarston, I. M., Tan, T. Y., Cameron, F., Werther, G., Hutson, J., O'Connell, M., Grover, S. R., Heloury, Y., Zacharin, M., Bergman, P., Kimber, C., Brown, J. & 7 others, Webb, N., Hunter, M. F., Lafferty, A. R., Harley, V., Koopman, P., Ayers, K. L. & Sinclair, A. H., 29 Nov 2016, In : Genome Biology. 17, 1, 21 p., 243.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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88 Citations (Scopus)

DNA methylation mediated up-regulation of TERRA non-coding RNA is coincident with elongated telomeres in the human placenta

Novakovic, B., Napier, C. E., Vryer, R., Dimitriadis, E., Manuelpillai, U., Sharkey, A., Craig, J. M., Reddel, R. R. & Saffery, R., 1 Nov 2016, In : Molecular Human Reproduction. 22, 11, p. 791-799 9 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Dummy/pacifier use in preterm infants increases blood pressure and improves heart rate control

Horne, R. S. C., Fyfe, K. L., Odoi, A., Athukoralage, A., Yiallourou, S. & Wong, F. Y-W., Feb 2016, In : Pediatric Research. 79, 2, p. 325-332 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Dysregulation of SRY in the male brain: a genetic basis for sex-biased neurological disorders

Loke, H., Pinares-Garcia, P., Czech, D., Harley, V. & Lee, J., 2016, p. 114 - 115. 2 p.

Research output: Contribution to conferencePoster

13 Citations (Scopus)

EGFRvIII: The promiscuous mutation

Greenall, S. A. & Johns, T. G., 4 Jul 2016, In : Cell Death Discovery. 2 p., 16049.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
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Endogenous inhibins regulate steroidogenesis in mouse TM3 Leydig cells by altering SMAD2 signalling

Wang, Y., Bilandzic, M., Ooi, G. T., Findlay, J. K. & Stenvers, K. L., 15 Nov 2016, In : Molecular and Cellular Endocrinology. 436, p. 68-77 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Erratum: Single sustained inflation followed by ventilation leads to rapid cardiorespiratory recovery but causes cerebral vascular leakage in asphyxiated near-term lambs (PLoS ONE (2016) 11:1 (e0146574) DOI: 10.1371/journal.pone.0146574))

Sobotka, K. S., Hooper, S. B., Crossley, K. J., Ong, T., Schmölzer, G. M., Barton, S. K., McDougall, A. R. A., Miller, S. L., Tolcos, M., Klingenberg, C. & Polglase, G. R., 1 May 2016, In : PLoS ONE. 11, 5, e0156193.

Research output: Contribution to journalComment / DebateOtherpeer-review

2 Citations (Scopus)

Estrogenic and cytotoxic potentials of compounds isolated from Millettia macrophylla Benth (Fabaceae): Towards a better understanding of its underlying mechanisms

Zingue, S., Tchoumtchoua, J., Ntsa, D. M., Sandjo, L. P., Cisilotto, J., Magne Nde, C. B., Winter, E., Awounfack, C. F., Ndinteh, D. T., Clyne, C., Njamen, D., Halabalaki, M. & Creczynski-Pasa, T. B., 26 Oct 2016, In : BMC Complementary and Alternative Medicine. 16, 1, 17 p., 421.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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9 Citations (Scopus)

Estrogenic effects of Ficus umbellata Vahl. (Moraceae) extracts and their ability to alleviate some menopausal symptoms induced by ovariectomy in Wistar rats

Zingue, S., Michel, T., Tchatchou, J., Magne Nde, C. B., Winter, E., Monchot, A., Awounfack, C. F., Djiogue, S., Clyne, C., Fernandez, X., Creczynski-Pasa, T. B. & Njamen, D., 17 Feb 2016, In : Journal of Ethnopharmacology. 179, p. 332-344 13 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Expansion of human hematopoietic stem/progenitor cells on decellularized matrix scaffolds

Tiwari, A., Tursky, M. L., Nekkanti, L. P., Jenkin, G., Kirkland, M. A. & Pande, G., 1 Feb 2016, In : Current Protocols in Stem Cell Biology. 36, p. 1C.15.1-1C.15.16 16 p.

Research output: Contribution to journalArticleOtherpeer-review

3 Citations (Scopus)

Exploring the Landscape of Palliative Care for People with Non-Hodgkin's Lymphoma: Do they Receive Quality End of Life Care?

Philip, J., Collins, A., Burchell, J. L., Ritchie, D., Le, B., Hudson, P., Currow, D., Mclachlan, S. A., Krishnasamy, M., Mileshkin, L. & Millar, J. L., Jun 2016, p. NP176-NP177. 2 p.

Research output: Contribution to conferencePoster

Exploring the Landscape of Palliative Care for People with Non-Hodgkin’s Lymphoma: Do They Receive Quality End-of-Life Care?

Collins, A., Burchell, J., Ritchie, D., Le, B., Sundararajan, V., Hudson, P., McLachlan, S-A., Krishnasamy, M., Millar, J. & Currow, D., Dec 2016, p. e151-e152. 2 p.

Research output: Contribution to conferencePoster

Fertile ground: Human endometrial programming and lessons in health and disease

Evans, J., Salamonsen, L. A., Winship, A., Menkhorst, E., Nie, G., Gargett, C. E. & Dimitriadis, E., Nov 2016, In : Nature Reviews Endocrinology. 12, p. 654-667 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

54 Citations (Scopus)

FGF9, activin and TGFβ promote testicular characteristics in an XX gonad organ culture model

Gustin, S. E., Stringer, J. M., Hogg, K., Sinclair, A. H. & Western, P. S., 1 Nov 2016, In : Reproduction. 152, 5, p. 529-543 15 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
7 Citations (Scopus)

Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade

Winship, A. L., Rainczuk, K. & Dimitriadis, E., 2 Jan 2016, In : Cancer Investigation. 34, 1, p. 26-31 6 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Gelsolin suppresses gastric cancer metastasis through inhibition of PKR-p38 signaling

Yuan, X., Wang, W., Li, J., Zheng, P., Dong, P., Chen, L., Zhou, Y., Xie, G., Xu, D., Liu, Y. & Shen, L., 13 Jul 2016, In : Oncotarget. 7, 33, p. 53459-53470 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

Global metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii

Maifiah, M. H. M., Cheah, S-E., Johnson, M. D., Han, M., Boyce, J. D., Thamlikitkul, V., Forrest, A., Kaye, K. S., Hertzog, P., Purcell, A. W., Song, J., Velkov, T., Creek, D. J. & Li, J., 29 Feb 2016, In : Scientific Reports. 6, 17 p., 22287.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

Gonadal peptides: Inhibins, activins, follistatin, and Müllerian-inhibiting substance (Antimüllerian hormone)

de Kretser, D. M., Hedger, M. P. & Burger, H. G., 2016, Endocrinology: Adult & Pediatric. Jameson, J. L., De Groot, L. J., de Kretser, D. M., Giudice, L. C., Grossman, A. B., Melmed, S., Potts Jr, J. T. & Weir, G. C. (eds.). 7th ed. Philadelphia PA USA: Elsevier, Vol. 1 and 2. p. 2037 - 2050 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Gonadotropin suppression in men leads to a reduction in claudin-11 at the Sertoli cell tight junction

McCabe, M. J., Tarulli, G. A., Laven-Law, G., Matthiesson, K. L., Meachem, S. J., McLachlan, R. I., Dinger, M. E. & Stanton, P. G., 18 Feb 2016, In : Human Reproduction. 31, 4, p. 875-886 12 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

High levels of HtrA4 observed in preeclamptic circulation drastically alter endothelial gene expression and induce inflammation in human umbilical vein endothelial cells

Wang, Y. & Nie, G., 1 Nov 2016, In : Placenta. 47, p. 46-55 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Hormonal evaluation in relation to phenotype and genotype in 286 patients with a disorder of sex development from Indonesia

Juniarto, A. Z., van der Zwan, Y. G., Santosa, A., Ariani, M. D., Eggers, S., Hersmus, R., Themmen, A. P. N., Bruggenwirth, H. T., Wolffenbuttel, K. P., Sinclair, A., White, S. J., Looijenga, L. H. J., de Jong, F. H., Faradz, S. M. H. & Drop, S. L. S., 1 Aug 2016, In : Clinical Endocrinology. 85, 2, p. 247-257 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

HPMCD: The database of human microbial communities from metagenomic datasets and microbial reference genomes

Forster, S. C., Browne, H. P., Kumar, N., Hunt, M., Denise, H., Mitchell, A., Finn, R. D. & Lawley, T. D., 2016, In : Nucleic Acids Research. 44, D1, p. D604-D609 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

Hsp90 and PKM2 drive the expression of aromatase in Li-Fraumeni syndrome breast adipose stromal cells

Subbaramaiah, K., Brown, K. A., Zahid, H., Balmus, G., Weiss, R. S., Herbert, B. S. & Dannenberg, A. J., 29 Jul 2016, In : Journal of Biological Chemistry. 291, 31, p. 16011-16023 13 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Human extravillous trophoblast invasion: Intrinsic and extrinsic regulation

Menkhorst, E., Winship, A., Van Sinderen, M. & Dimitriadis, E., 2016, In : Reproduction, Fertility and Development. 28, 4, p. 406-415 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

14 Citations (Scopus)

Hyperglycosylated hCG: a Unique Human Implantation and Invasion Factor

Evans, J., 1 Mar 2016, In : American Journal of Reproductive Immunology. 75, 3, p. 333-340 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

21 Citations (Scopus)

Identifying late-onset fetal growth restriction by measuring circulating placental RNA in the maternal blood at 28 weeks' gestation

Whitehead, C. L., McNamara, H. C., Walker, S. P., Alexiadis, M., Fuller, P. J., Vickers, D. K., Hannan, N. J., Hastie, R., Tuohey, L., Kaitu'u-Lino, T. J. & Tong, S., 1 Apr 2016, In : American Journal of Obstetrics and Gynecology. 214, 4, p. 1 - 8 8 p., 521.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

IL6 trans-signaling promotes KRAS-driven lung carcinogenesis

Brooks, G. D., McLeod, L., Alhayyani, S., Miller, A., Russell, P. A., Ferlin, W., Rose-John, S., Ruwanpura, S. & Jenkins, B. J., 15 Feb 2016, In : Cancer Research. 76, 4, p. 866-876 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
43 Citations (Scopus)

Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors

Leung, T. H., Fuller, P. J. & Chu, S., 2016, In : International Journal of Biochemistry and Cell Biology. 72, p. 51 - 54 4 p.

Research output: Contribution to journalArticleOtherpeer-review

19 Citations (Scopus)

Impact of intra- and extrauterine growth on bone mineral density and content in the neonatal period of very-low-birth-weight infants

Li, J., Funato, M., Tamai, H., Wada, H., Nishihara, M., Morita, T., Miller, S. L. & Egashira, K., 2016, In : Early Human Development. 92, p. 1 - 6 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)