Hudson Institute - Department of Molecular and Translational Science

Research Output

2017

Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood

Li, Y., Salamonsen, L. A., Hyett, J., Da Silva Costa, F. & Nie, G-Y., 4 Jul 2017, In : Scientific Reports. 7, 1, 4627.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Mechanism of interferon-stimulated gene induction in HIV-1- infected macrophages

Nasr, N., Alshehri, A. A., Wright, T. K., Shahid, M., Heiner, B. M., Harman, A. N., Botting, R. A., Helbig, K. J., Beard, M. R., Suzuki, K., Kelleher, A. D., Hertzog, P. & Cunningham, A. L., 1 Oct 2017, In : Journal of Virology. 91, 20, 19 p., e00744-17.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Menopause is a determinant of breast aromatase expression and its associations with BMI, inflammation, and systemic markers

Brown, K. A., Iyengar, N. M., Zhou, X. K., Gucalp, A., Subbaramaiah, K., Wang, H., Giri, D. D., Morrow, M., Falcone, D. J., Wendel, N. K., Winston, L. A., Pollak, M., Dierickx, A., Hudis, C. A. & Dannenberg, A. J., 1 May 2017, In : The Journal of Clinical Endocrinology and Metabolism. 102, 5, p. 1692-1701 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
27 Citations (Scopus)

Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori

Srikhanta, Y. N., Gorrell, R. J., Power, P., Tsyganov, K., Boitano, M., Clark, T. A., Korlach, J., Hartland, E. L., Jennings, M. P. & Kwok, T., 1 Dec 2017, In : Scientific Reports. 7, 1, 14 p., 16140.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

MIR-127 promotes EMT and stem-like traits in lung cancer through a feed-forward regulatory loop

Shi, L., Wang, Y., Lu, Z., Zhang, H., Zhuang, N., Wang, B., Song, Z., Chen, G., Huang, C., Xu, D., Zhang, Y., Zhang, W. & Gao, Y., 23 Mar 2017, In : Oncogene. 36, 12, p. 1631-1643 13 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

miR-155 dysregulation and therapeutic intervention in multiple sclerosis

McCoy, C. E., 2017, Regulation of Inflammatory Signaling in Health and Disease. Xu, D. (ed.). Singapore: Springer, p. 111-131 21 p. (Advances in Experimental Medicine and Biology; vol. 1024).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

8 Citations (Scopus)

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns

Lee, W. T., Sun, X., Tsai, T-S., Johnson, J. L., Gould, J. A., Garama, D. J., Gough, D. J., McKenzie, M., Trounce, I. A. & St John, J. C., 1 Jan 2017, In : Cell Death Discovery. 3, 11 p., 17062.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells

Vaghjiani, V., Cain, J. E., Lee, W., Vaithilingam, V., Tuch, B. E. & St John, J. C., 15 Oct 2017, In : Stem Cells and Development. 26, 20, p. 1505-1519 15 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Monocytes and dendritic cells are the primary sources of interleukin 37 in human immune cells

Rudloff, I., Cho, S. X., Lao, J. C., Ngo, D., McKenzie, M., Nold-Petry, C. A. & Nold, M. F., 1 Apr 2017, In : Journal of leukocyte biology. 101, 4, p. 901-911 11 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Multiple soluble TGF-β receptors in addition to soluble endoglin are elevated in preeclamptic serum and they synergistically inhibit TGF-β signaling

Wang, Y., Chen, Q., Zhao, M., Walton, K., Harrison, C. & Nie, G., 1 Aug 2017, In : The Journal of Clinical Endocrinology and Metabolism. 102, 8, p. 3065-3074 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Naturally existing isoforms of miR-222 have distinct functions

Yu, F., Pillman, K. A., Neilsen, C. T., Toubia, J., Lawrence, D. M., Tsykin, A., Gantier, M. P., Callen, D. F., Goodall, G. J. & Bracken, C. P., 1 Jan 2017, In : Nucleic Acids Research. 45, 19, p. 11371-11385 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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27 Citations (Scopus)

N-cadherin identifies human endometrial epithelial progenitor cells by in vitro stem cell assays

Nguyen, H. P. T., Xiao, L., Deane, J. A., Tan, K. S., Cousins, F. L., Masuda, H., Sprung, C. N., Rosamilia, A. & Gargett, C. E., 1 Nov 2017, In : Human Reproduction. 32, 11, p. 2254-2268 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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25 Citations (Scopus)

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort

Williams, T. A., Lenders, J. W. M., Mulatero, P., Burrello, J., Rottenkolber, M., Adolf, C., Satoh, F., Amar, L., Quinkler, M., Deinum, J., Beuschlein, F., Kitamoto, K. K., Pham, U., Morimoto, R., Umakoshi, H., Prejbisz, A., Kocjan, T., Naruse, M., Stowasser, M., Nishikawa, T. & 5 others, Young, W. F., Gomez-Sanchez, C. E., Funder, J. W., Reincke, M. & for the Primary Aldosteronism Surgery Outcome (PASO) investigators, 1 Sep 2017, In : The Lancet Diabetes and Endocrinology. 5, 9, p. 689-699 11 p.

Research output: Contribution to journalArticleResearchpeer-review

186 Citations (Scopus)

Outer membrane vesicles prime and activate macrophage inflammasomes and cytokine secretion in vitro and in vivo

Cecil, J. D., O'Brien-Simpson, N. M., Lenzo, J. C., Holden, J. A., Singleton, W. C. J., Perez-Gonzalez, A., Mansell, A. & Reynolds, E. C., 25 Aug 2017, In : Frontiers in Immunology. 8, AUG, 22 p., 1017.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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21 Citations (Scopus)

Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer

Yan, F., Ying, L., Li, X., Qiao, B., Meng, Q., Yu, L., Yuan, X., Ren, S. T., Chan, D. W., Shi, L., Ni, P., Wang, X., Xu, D. & Hu, Y., 2017, In : Oncotarget. 8, 29, p. 47020-47036 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

PB1-F2 peptide derived from avian influenza A virus H7N9 induces inflammation via activation of the NLRP3 inflammasome

Pinar, A., Dowling, J. K., Bitto, N. J., Robertson, A. A. B., Latz, E., Stewart, C. R., Drummond, G. R., Cooper, M. A., McAuley, J. L., Tate, M. D. & Mansell, A., 20 Jan 2017, In : The Journal of Biological Chemistry. 292, 3, p. 826-836 11 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Pentosan polysulfate binds to STRO-1+ mesenchymal progenitor cells, is internalized, and modifies gene expression: A novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis

Wu, J., Shimmon, S., Paton, S., Daly, C., Goldschlager, T., Gronthos, S., Zannettino, A. C. W. & Ghosh, P., 13 Dec 2017, In : Stem Cell Research and Therapy. 8, 1, 15 p., 278.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Perinatal brain injury as a consequence of preterm birth and intrauterine inflammation: Designing targeted stem cell therapies

Paton, M. C. B., McDonald, C. A., Allison, B. J., Fahey, M. C., Jenkin, G. & Miller, S. L., 10 Apr 2017, In : Frontiers in Neuroscience. 11, APR, 12 p., 200.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

Phosphoproteomic profiling reveals ALK and MET as novel actionable targets across synovial sarcoma subtypes

Fleuren, E. D. G., Vlenterie, M., Van Der Graaf, W. T. A., Hillebrandt-Roeffen, M. H. S., Blackburn, J., Ma, X., Chan, H., Magias, M. C., Van Erp, A., Van Houdt, L., Cebeci, S. A. S., Van De Ven, A., Flucke, U. E., Heyer, E. E., Thomas, D. M., Lord, C. J., Marini, K. D., Vaghjiani, V., Mercer, T. R., Cain, J. E. & 3 others, Wu, J., Versleijen-Jonkers, Y. M. H. & Daly, R. J., 15 Aug 2017, In : Cancer Research. 77, 16, p. 4279-4292 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

Porphyromonas gulae activates unprimed and gamma interferon-primed macrophages via the pattern recognition receptors Toll-like receptor 2 (TLR2), TLR4, and NOD2

Holden, J. A., O'Brien-Simpson, N. M., Lenzo, J. C., Orth, R. K. H., Mansell, A. & Reynolds, E. C., 1 Sep 2017, In : Infection and Immunity. 85, 9, 15 p., e00282-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

Positional modification techniques for supine obstructive sleep apnea: A systematic review and meta-analysis

Barnes, H., Edwards, B. A., Joosten, S. A., Naughton, M. T., Hamilton, G. S. & Dabscheck, E., Dec 2017, In : Sleep Medicine Reviews. 36, p. 107-115 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

30 Citations (Scopus)

Positive regulatory interactions between YAP and Hedgehog signalling in skin homeostasis and BCC development in mouse skin in vivo

Akladios, B., Mendoza Reinoso, V., Cain, J. E., Wang, T., Lambie, D. L., Watkins, D. N. & Beverdam, A., 1 Aug 2017, In : PLoS ONE. 12, 8, 15 p., e0183178.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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9 Citations (Scopus)

Post-translational Mechanisms of Host Subversion by Bacterial Effectors

Scott, N. E. & Hartland, E. L., 1 Dec 2017, In : Trends in Molecular Medicine. 23, 12, p. 1088-1102 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Posttranslational modification as a critical determinant of cytoplasmic innate immune recognition

Baker, P. J., De Nardo, D., Moghaddas, F., Tran, L. S., Bachem, A., Nguyen, T., Hayman, T., Tye, H., Vince, J. E., Bedoui, S., Ferrero, R. L. & Masters, S. L., 14 Jun 2017, In : Physiological Reviews. 97, 3, p. 1165-1209 45 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

18 Citations (Scopus)

Potential efficacy of interleukin-1β inhibition in lung cancer

Jenkins, B. J., 21 Oct 2017, In : The Lancet. 390, 10105, p. 1813-1814 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
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3 Citations (Scopus)

Potential pitfall of pluripotent stem cells

Trounson, A., 3 Aug 2017, In : The New England Journal of Medicine. 377, 5, p. 490-491 2 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

10 Citations (Scopus)

PRC2 is required for extensive reorganization of H3K27me3 during epigenetic reprogramming in mouse fetal germ cells

Prokopuk, L., Stringer, J. M., Hogg, K., Elgass, K. D. & Western, P. S., 20 Feb 2017, In : Epigenetics and Chromatin. 10, 1, 20 p., 7.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Red Cell Alloimmunisation Is Associated with Development of Autoantibodies and Increased Red Cell Transfusion Requirements in Myelodysplastic Syndromes (MDS)

Singhal, D., Kutyna, M. M., Chhetri, R., Wee, A., Hague, S., Nath, L., Nath, S. V., Sinha, R., Wickham, N., Lewis, I. D., Ross, D. M., Bardy, P. G., To, L. B., Reynolds, J., Wood, E., Roxby, D. J. & Hiwase, D. K., 7 Dec 2017, In : Blood. 130, Suppl 1, p. 2411 1 p.

Research output: Contribution to journalMeeting AbstractOtherpeer-review

Regional reproductive quests: Cross-border reproductive travel among infertile Indonesian couples

Bennett, L. & Pangestu, M., 1 Aug 2017, In : Asia Pacific Viewpoint. 58, 2, p. 162-174 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Regulation and functions of inflammasome-mediated cytokines in Helicobacter pylori infection

Tran, L. S., Chonwerawong, M. & Ferrero, R. L., 2017, In : Microbes and Infection. 19, 9-10, p. 449-458 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

12 Citations (Scopus)

Risk Factors for Hospital Readmission and Follow Up after NICU Discharge of Infants Born at Extremely Low Gestational Age in Metropolitan Melbourne

Doctor, T. N., Harnaen, E., Seith, B., Tan, K. & Craig, S., 2017, In : International Journal of Pediatric Research. 3, 1, 7 p., 028.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Serum podocalyxin is significantly increased in early-onset preeclampsia and may represent a novel marker of maternal endothelial cell dysfunction

Chen, Q., Wang, Y., Li, Y., Zhao, M. & Nie, G., Nov 2017, In : Journal of Hypertension. 35, 11, p. 2287-2294 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition

Nguyen, T. A., Smith, B. R. C., Tate, M. D., Belz, G. T., Barrios, M. H., Elgass, K. D., Weisman, A. S., Baker, P. J., Preston, S. P., Whitehead, L. W., Garnham, A. L., Lundie, R. J., Smyth, G. K., Pellegrini, M., O'Keeffe, M., Wicks, I. P., Masters, S. L., Hunter, C. P. & Pang, K. C., 19 Sep 2017, In : Immunity. 47, 3, p. 498-509 12 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Signaling by TGF-betas in tubule cultures of adult rat testis

Chan, K. H., Galuska, S. P., Kudipudi, P. K., Riaz, M. A., Loveland, K. L. & Konrad, L., 2017, In : American Journal of Translational Research. 9, 3, p. 1173-1182 10 p., AJTR0034593.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Simultaneous measurement of mitochondrial calcium and mitochondrial membrane potential in live cells by fluorescent microscopy

McKenzie, M., Lim, S. C. & Duchen, M. R., 24 Jan 2017, In : Journal of Visualized Experiments. 2017, 119, 6 p., e55166.

Research output: Contribution to journalArticleOtherpeer-review

9 Citations (Scopus)

Soluble Delta-like ligand 1 alters human endometrial epithelial cell adhesive capacity

Van Sinderen, M., Oyanedel, J., Menkhorst, E., Cuman, C., Rainczuk, K., Winship, A., Salamonsen, L., Edgell, T. & Dimitriadis, E., 2017, In : Reproduction, Fertility and Development. 29, 4, p. 694-702 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling

Hughes, M. M., Lavrencic, P., Coll, R. C., Ve, T., Ryan, D. G., Williams, N. C., Menon, D., Mansell, A., Board, P. G., Mobli, M., Kobe, B. & O’Neill, L. A. J., 8 Aug 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 32, p. E6480-E6489 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

Ve, T., Vajjhala, P. R., Hedger, A., Croll, T., Dimaio, F., Horsefield, S., Yu, X., Lavrencic, P., Hassan, Z., Morgan, G. P., Mansell, A., Mobli, M., O'Carroll, A., Chauvin, B., Gambin, Y., Sierecki, E., Landsberg, M. J., Stacey, K. J., Egelman, E. H. & Kobe, B., 7 Sep 2017, In : Nature Structural & Molecular Biology. 24, 9, p. 743-751 9 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

Kedzierski, L., Tate, M., Hsu, A. C., Kolesnik, T. B., Linossi, E. M., Dagley, L., Dong, Z., Freeman, S., Infusini, G., Starkey, M. R., Bird, N. L., Chatfield, S. M., Babon, J. J., Huntington, N., Belz, G., Webb, A., Wark, P. AB., Nicola, N. A., Xu, J., Kedzierska, K. & 2 others, Hansbro, P. M. & Nicholson, S. E., 14 Feb 2017, In : eLife. 6, 27 p., e20444.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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28 Citations (Scopus)

Survey of reproductive experiences and outcomes of cancer survivors who stored reproductive material before treatment

Hammarberg, K., Kirkman, M., Stern, C., McLachlan, R. I., Clarke, G., Agresta, F., Gook, D., Rombauts, L., Vollenhoven, B. & Fisher, J. R. W., 1 Jan 2017, In : Human Reproduction. 32, 12, p. 2423-2430 8 p., dex314.

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Targeted Therapy for Severe Asthma: Identifying the Right Patients

Low, K. & Bardin, P. G., 1 Jun 2017, In : Molecular Diagnosis and Therapy. 21, 3, p. 235-247 13 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Targeting the seeds of small cell lung cancer

Mahara, S. & Firestein, R., 1 Mar 2017, In : Annals of Translational Medicine. 5, 5, 113.

Research output: Contribution to journalArticleOtherpeer-review

Testis determination requires a specific FGFR2 isoform to repress FOXL2

Bagheri-Fam, S., Bird, A. D., Zhao, L., Ryan, J. M., Yong, M., Wilhelm, D., Koopman, P., Eswarakumar, V. P. & Harley, V. R., 1 Nov 2017, In : Endocrinology. 158, 11, p. 3832-3843 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

The human amnion epithelial cell secretome decreases hepatic fibrosis in mice with chronic liver fibrosis

Alhomrani, M., Correia, J., Zavou, M., Leaw, B., Kuk, N., Xu, R., Saad, M. I., Hodge, A., Greening, D. W., Lim, R. & Sievert, W., 24 Oct 2017, In : Frontiers in Pharmacology. 8, OCT, 13 p., 748.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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17 Citations (Scopus)

The immune modulatory peptide FhHDM-1 secreted by the helminth Fasciola hepatica prevents NLRP3 inflammasome activation by inhibiting endolysosomal acidification in macrophages

Alvarado, R., To, J., Lund, M. E., Pinar, A., Mansell, A., Robinson, M. W., O'Brien, B. A., Dalton, J. P. & Donnelly, S. M., 1 Jan 2017, In : The FASEB Journal. 31, 1, p. 85-95 11 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

The innate immune receptor MDA5 limits rotavirus infection but promotes cell death and pancreatic inflammation

Dou, Y., Yim, H. C. H., Kirkwood, C. D., Williams, B. R. G. & Sadler, A. J., 15 Sep 2017, In : The EMBO Journal. 36, 18, p. 2742-2757 16 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

The molecular characterization of porcine egg precursor cells

Tsai, T-S., Johnson, J., White, Y. & St John, J. C., 2017, In : Oncotarget. 8, 38, p. 63484-63505 22 p.

Research output: Contribution to journalArticleResearchpeer-review

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The nicer side of innate immunity: Wound healing and tissue regeneration

Sweet, M. J. & Mansell, A., 1 Jan 2017, In : Seminars in Cell and Developmental Biology. 61, p. 1-2 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

The ovarian reserve is depleted during puberty in a hormonally driven process dependent on the pro-Apoptotic protein BMF

Liew, S. H., Nguyen, Q. N., Strasser, A., Findlay, J. K. & Hutt, K. J., 3 Aug 2017, In : Cell Death and Disease. 8, 8, e2971.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

The presence and impact of estrogen metabolism on the biology of triple-negative breast cancer

McNamara, K. M., Oguro, S., Omata, F., Kikuchi, K., Guestini, F., Suzuki, K., Yang, Y., Abe, E., Hirakawa, H., Brown, K. A., Takanori, I., Ohuchi, N. & Sasano, H., 1 Jan 2017, In : Breast Cancer Research and Treatment. 161, 2, p. 213-227 15 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)