Hudson Institute - Department of Molecular and Translational Science

Research Output

2017

Editorial

Brown, K. A., Chin Boon, W. & Clyne, C. D., 1 Jun 2017, In : Journal of Steroid Biochemistry and Molecular Biology. 170, p. 1 1 p.

Research output: Contribution to journalEditorialOtherpeer-review

Editorial overview: Offence is the best defense: host–pathogen interactions driving evolution of human immunity and the germs we live with

Pellegrini, M. & Hartland, E., 1 Oct 2017, In : Current Opinion in Immunology. 48, p. x-xi 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Effects of the central potassium ions on the G-quadruplex and stabilizer binding

Wang, Z. & Liu, J. P., 1 Mar 2017, In : Journal of Molecular Graphics and Modelling. 72, p. 168-177 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Endocrinology of the male reproductive system and spermatogenesis

O'Donnell, L., Stanton, P. & de Kretser, D. M., 2017, Endocrinology of Male Reproduction. Feingold, KR., Anawalt, B. & Boyce, A. (eds.). USA: Endotext, p. 1-69 69 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other

Open Access

Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors

Berry, W., Algar, E., Kumar, B., Desmond, C., Swan, M., Jenkins, B. J. & Croagh, D., 15 May 2017, In : International Journal of Cancer. 140, 10, p. 2331-2343 13 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Erratum to: Mutational landscape of mucinous ovarian carcinoma and its neoplastic precursors. [Genome Med. 7 (2015) (87)]

Ryland, G. L., Hunter, S. M., Doyle, M. A., Caramia, F., Li, J., Rowley, S. M., Christie, M., Allan, P. E., Stephens, A. N., Bowtell, D. D. L., Campbell, I. G. & Gorringe, K. L., 12 Jan 2017, In : Genome Medicine. 9, 1, 1.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
1 Citation (Scopus)

Expression of Biglycan in First Trimester Chorionic Villous Sampling Placental Samples and Altered Function in Telomerase-Immortalized Microvascular Endothelial Cells

Chui, A., Gunatillake, T., Brennecke, S. P., Ignjatovic, V., Monagle, P. T., Whitelock, J. M., Van Zanten, D. E., Eijsink, J., Wang, Y., Deane, J., Borg, A. J., Stevenson, J., Erwich, J. J., Said, J. M. & Murthi, P., 1 Jun 2017, In : Arteriosclerosis, Thrombosis and Vascular Biology. 37, 6, p. 1168-1179 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Follistatin attenuates radiation-induced fibrosis in a murine model

Forrester, H. B., De Kretser, D. M., Leong, T., Hagekyriakou, J. & Sprung, C. N., 1 Mar 2017, In : PLoS ONE. 12, 3, 13 p., e0173788.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Genetics and genomics of ovarian sex cord-stromal tumors

Fuller, P. J., Leung, D. & Chu, S., 1 Feb 2017, In : Clinical Genetics. 91, 2, p. 285-291 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

16 Citations (Scopus)

Genetic variation at the Th2 immune gene IL13 is associated with IgE-mediated paediatric food allergy

Ashley, S. E., Tan, H. T. T., Peters, R., Allen, K. J., Vuillermin, P., Dharmage, S. C., Tang, M. L. K., Koplin, J., Lowe, A., Ponsonby, A. L., Molloy, T. J., Matheson, M. C., Saffery, R., Ellis, J. A., De Martino, D. & the HealthNuts team, 1 Aug 2017, In : Clinical & Experimental Allergy. 47, 8, p. 1032-1037 6 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Ghrelin and breast cancer: Emerging roles in obesity, estrogen regulation, and cancer

Au, C. C., Furness, J. B. & Brown, K. A., 9 Jan 2017, In : Frontiers in Oncology. 6, JAN, 7 p., 265.

Research output: Contribution to journalShort SurveyOtherpeer-review

Open Access
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7 Citations (Scopus)

Hero turned villain: NLRP3 inflammasome-induced inflammation during influenza A virus infection

Ong, J. D. H., Mansell, A. & Tate, M. D., Jun 2017, In : Journal of leukocyte biology. 101, 4, p. 863-874 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

19 Citations (Scopus)
15 Citations (Scopus)

Human Metapneumovirus Infection in Chronic Obstructive Pulmonary Disease: Impact of Glucocorticosteroids and Interferon

Kan-o, K., Sanchez-Ramirez, R., Macdonald, M. I., Rolph, M. S., Rudd, P. A., Spann, K. M., Mahalingam, S., Bardin, P. G. & Thomas, B. J., 15 May 2017, In : Journal of Infectious Diseases. 215, 10, p. 1536-1545 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Identification of a histone family gene signature for predicting the prognosis of cervical cancer patients

Li, X., Tian, R., Gao, H., Yang, Y., Williams, B. R. G., Gantier, M. P., McMillan, N. A. J., Xu, D., Hu, Y. & Gao, YE., 1 Dec 2017, In : Scientific Reports. 7, 1, 13 p., 16495.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Identification of a TLR2-regulated gene signature associated with tumor cell growth in gastric cancer

West, AC., Tang, K., Tye, H., Yu, L., Deng, N., Najdovska, M., Lin, S. J., Balic, JJ., Okochi-Takada, E., McGuirk, P., Keogh, B., McCormack, W., Bhathal, P. S., Reilly, M., Oshima, M., Ushijima, T., Tan, P. & Jenkins, B. J., 7 Sep 2017, In : Oncogene. 36, 36, p. 5134-5144 11 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

If a butterfly flaps its wings in the Amazon, do we form an Inflammasome?

Mansell, A., 1 Jun 2017, In : Molecular Immunology. 86, p. 1-2 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism

Liu, J-P., Li, J., Lu, Y., Wang, L. & Chen, G., 1 Feb 2017, In : Clinical and Experimental Pharmacology and Physiology. 44, 2, p. 172-179 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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2 Citations (Scopus)

Integrin-linked kinase expression in myeloid cells promotes inflammatory signaling during experimental colitis

Ahmed, A. U., Yim, H. C. H., Alorro, M. G., Ernst, M. & Williams, B. R. G., 15 Sep 2017, In : Journal of Immunology. 199, 6, p. 2128-2139 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Interferon epsilon promotes HIV restriction at multiple steps of viral replication

Garcia-Minambres, A., Eid, S. G., Mangan, N. E., Pade, C., Lim, S. S., Matthews, A. Y., de Weerd, N. A., Hertzog, P. J. & Johnson, M., May 2017, In : Immunology and Cell Biology. 95, 5, p. 478-483 6 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Interleukin-11-driven gastric tumourigenesis is independent of trans-signalling

Balic, J. J., Garbers, C., Rose-John, S., Yu, L. & Jenkins, B. J., 1 Apr 2017, In : Cytokine. 92, p. 118-123 6 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Interleukin-11 induces preterm birth and modulates decidual inflammasome gene expression in mice

Winship, A. & Dimitriadis, E., Feb 2017, In : Placenta. 50, p. 99-101 3 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Interleukin-11 up-regulates endoplasmic reticulum stress induced target, PDIA4 in human first trimester placenta and in vivo in mice

Winship, A. L., Sorby, K., Correia, J., Rainczuk, A., Yap, J. & Dimitriadis, E., 1 May 2017, In : Placenta. 53, p. 92-100 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Interleukin 6 Present in inflammatory ascites from advanced epithelial ovarian cancer patients promotes tumor necrosis factor receptor 2-expressing regulatory T cells

Kampan, N. C., Madondo, M. T., McNally, O. M., Stephens, A. N., Quinn, M. A. & Plebanski, M., 6 Nov 2017, In : Frontiers in Immunology. 8, NOV, 14 p., 1482.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Invasive trophoblast promote stromal fibroblast decidualization via Profilin 1 and ALOX5

Menkhorst, E. M., Van Sinderen, M. L., Rainczuk, K., Cuman, C., Winship, A. & Dimitriadis, E., 1 Dec 2017, In : Scientific Reports. 7, 1, 11 p., 8690.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

In vivo evidence that RBM5 is a tumour suppressor in the lung

Jamsai, D., Watkins, D. N., O'Connor, A. E., Merriner, D. J., Gursoy, S., Bird, A. D., Kumar, B., Miller, A., Cole, T. J., Jenkins, B. J. & O'Bryan, M. K., 1 Dec 2017, In : Scientific Reports. 7, 1, 8 p., 15874.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

JNK activation of BIM promotes hepatic oxidative stress, steatosis, and insulin resistance in obesity

Litwak, S. A., Pang, L., Galic, S., Igoillo-Esteve, M., Stanley, W. J., Turatsinze, J. V., Loh, K., Thomas, H. E., Sharma, A., Trepo, E., Moreno, C., Gough, D. J., Eizirik, D. L., De Haan, J. B. & Gurzov, E. N., 1 Dec 2017, In : Diabetes. 66, 12, p. 2973-2986 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse

Dunleavy, J. E. M., Okuda, H., O’Connor, A. E., Merriner, D. J., O’Donnell, L., Jamsai, D., Bergmann, M. & O’Bryan, M. K., 14 Nov 2017, In : PLoS Genetics. 13, 11, 28 p., e1007078.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Length does matter for cGAS

Gantier, M. P., 1 Oct 2017, In : EMBO Reports. 18, 10, p. 1675-1676 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

3 Citations (Scopus)

Lumbar microdiscectomy and post-operative activity restrictions: A protocol for a single blinded randomised controlled trial

Daly, C. D., Lim, K. Z., Lewis, J. A., Saber, K., Molla, M., Bar-Zeev, N. & Goldschlager, T., 20 Jul 2017, In : BMC Musculoskeletal Disorders. 18, 1, 8 p., 312.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
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3 Citations (Scopus)

Lung ultrasound immediately after birth to describe normal neonatal transition: An observational study

Blank, D. A., Farouk Kamlin, C. O., Rogerson, S. R., Fox, L. M., Lorenz, L., Kane, S. C., Polglase, G. R., Hooper, S. B. & Davis, P. G., 28 Jun 2017, In : Archives of Disease in Childhood. 103, 2, p. F157-F162 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Manipulating the mitochondrial genome to enhance cattle embryo development

Srirattana, K. & St. John, J. C., 1 Jul 2017, In : G3: Genes, Genomes, Genetics. 7, 7, p. 2065-2080 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood

Li, Y., Salamonsen, L. A., Hyett, J., Da Silva Costa, F. & Nie, G-Y., 4 Jul 2017, In : Scientific Reports. 7, 1, 4627.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Mechanism of interferon-stimulated gene induction in HIV-1- infected macrophages

Nasr, N., Alshehri, A. A., Wright, T. K., Shahid, M., Heiner, B. M., Harman, A. N., Botting, R. A., Helbig, K. J., Beard, M. R., Suzuki, K., Kelleher, A. D., Hertzog, P. & Cunningham, A. L., 1 Oct 2017, In : Journal of Virology. 91, 20, 19 p., e00744-17.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Menopause is a determinant of breast aromatase expression and its associations with BMI, inflammation, and systemic markers

Brown, K. A., Iyengar, N. M., Zhou, X. K., Gucalp, A., Subbaramaiah, K., Wang, H., Giri, D. D., Morrow, M., Falcone, D. J., Wendel, N. K., Winston, L. A., Pollak, M., Dierickx, A., Hudis, C. A. & Dannenberg, A. J., 1 May 2017, In : The Journal of Clinical Endocrinology and Metabolism. 102, 5, p. 1692-1701 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
22 Citations (Scopus)

Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori

Srikhanta, Y. N., Gorrell, R. J., Power, P., Tsyganov, K., Boitano, M., Clark, T. A., Korlach, J., Hartland, E. L., Jennings, M. P. & Kwok, T., 1 Dec 2017, In : Scientific Reports. 7, 1, 14 p., 16140.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

MIR-127 promotes EMT and stem-like traits in lung cancer through a feed-forward regulatory loop

Shi, L., Wang, Y., Lu, Z., Zhang, H., Zhuang, N., Wang, B., Song, Z., Chen, G., Huang, C., Xu, D., Zhang, Y., Zhang, W. & Gao, Y., 23 Mar 2017, In : Oncogene. 36, 12, p. 1631-1643 13 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

miR-155 dysregulation and therapeutic intervention in multiple sclerosis

McCoy, C. E., 2017, Regulation of Inflammatory Signaling in Health and Disease. Xu, D. (ed.). Singapore: Springer, p. 111-131 21 p. (Advances in Experimental Medicine and Biology; vol. 1024).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

8 Citations (Scopus)

Mitochondrial DNA haplotypes induce differential patterns of DNA methylation that result in differential chromosomal gene expression patterns

Lee, W. T., Sun, X., Tsai, T-S., Johnson, J. L., Gould, J. A., Garama, D. J., Gough, D. J., McKenzie, M., Trounce, I. A. & St John, J. C., 1 Jan 2017, In : Cell Death Discovery. 3, 11 p., 17062.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Modulation of mitochondrial DNA copy number to induce hepatocytic differentiation of human Amniotic Epithelial cells

Vaghjiani, V., Cain, J. E., Lee, W., Vaithilingam, V., Tuch, B. E. & St John, J. C., 15 Oct 2017, In : Stem Cells and Development. 26, 20, p. 1505-1519 15 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Monocytes and dendritic cells are the primary sources of interleukin 37 in human immune cells

Rudloff, I., Cho, S. X., Lao, J. C., Ngo, D., McKenzie, M., Nold-Petry, C. A. & Nold, M. F., 1 Apr 2017, In : Journal of leukocyte biology. 101, 4, p. 901-911 11 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Multiple soluble TGF-β receptors in addition to soluble endoglin are elevated in preeclamptic serum and they synergistically inhibit TGF-β signaling

Wang, Y., Chen, Q., Zhao, M., Walton, K., Harrison, C. & Nie, G., 1 Aug 2017, In : The Journal of Clinical Endocrinology and Metabolism. 102, 8, p. 3065-3074 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Naturally existing isoforms of miR-222 have distinct functions

Yu, F., Pillman, K. A., Neilsen, C. T., Toubia, J., Lawrence, D. M., Tsykin, A., Gantier, M. P., Callen, D. F., Goodall, G. J. & Bracken, C. P., 1 Jan 2017, In : Nucleic Acids Research. 45, 19, p. 11371-11385 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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26 Citations (Scopus)

N-cadherin identifies human endometrial epithelial progenitor cells by in vitro stem cell assays

Nguyen, H. P. T., Xiao, L., Deane, J. A., Tan, K. S., Cousins, F. L., Masuda, H., Sprung, C. N., Rosamilia, A. & Gargett, C. E., 1 Nov 2017, In : Human Reproduction. 32, 11, p. 2254-2268 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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21 Citations (Scopus)

Outcomes after adrenalectomy for unilateral primary aldosteronism: an international consensus on outcome measures and analysis of remission rates in an international cohort

Williams, T. A., Lenders, J. W. M., Mulatero, P., Burrello, J., Rottenkolber, M., Adolf, C., Satoh, F., Amar, L., Quinkler, M., Deinum, J., Beuschlein, F., Kitamoto, K. K., Pham, U., Morimoto, R., Umakoshi, H., Prejbisz, A., Kocjan, T., Naruse, M., Stowasser, M., Nishikawa, T. & 5 others, Young, W. F., Gomez-Sanchez, C. E., Funder, J. W., Reincke, M. & for the Primary Aldosteronism Surgery Outcome (PASO) investigators, 1 Sep 2017, In : The Lancet Diabetes and Endocrinology. 5, 9, p. 689-699 11 p.

Research output: Contribution to journalArticleResearchpeer-review

165 Citations (Scopus)

Outer membrane vesicles prime and activate macrophage inflammasomes and cytokine secretion in vitro and in vivo

Cecil, J. D., O'Brien-Simpson, N. M., Lenzo, J. C., Holden, J. A., Singleton, W. C. J., Perez-Gonzalez, A., Mansell, A. & Reynolds, E. C., 25 Aug 2017, In : Frontiers in Immunology. 8, AUG, 22 p., 1017.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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18 Citations (Scopus)

Overexpression of the transcription factor ATF3 with a regulatory molecular signature associates with the pathogenic development of colorectal cancer

Yan, F., Ying, L., Li, X., Qiao, B., Meng, Q., Yu, L., Yuan, X., Ren, S. T., Chan, D. W., Shi, L., Ni, P., Wang, X., Xu, D. & Hu, Y., 2017, In : Oncotarget. 8, 29, p. 47020-47036 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

PB1-F2 peptide derived from avian influenza A virus H7N9 induces inflammation via activation of the NLRP3 inflammasome

Pinar, A., Dowling, J. K., Bitto, N. J., Robertson, A. A. B., Latz, E., Stewart, C. R., Drummond, G. R., Cooper, M. A., McAuley, J. L., Tate, M. D. & Mansell, A., 20 Jan 2017, In : Journal of Biological Chemistry. 292, 3, p. 826-836 11 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Pentosan polysulfate binds to STRO-1+ mesenchymal progenitor cells, is internalized, and modifies gene expression: A novel approach of pre-programing stem cells for therapeutic application requiring their chondrogenesis

Wu, J., Shimmon, S., Paton, S., Daly, C., Goldschlager, T., Gronthos, S., Zannettino, A. C. W. & Ghosh, P., 13 Dec 2017, In : Stem Cell Research and Therapy. 8, 1, 15 p., 278.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Perinatal brain injury as a consequence of preterm birth and intrauterine inflammation: Designing targeted stem cell therapies

Paton, M. C. B., McDonald, C. A., Allison, B. J., Fahey, M. C., Jenkin, G. & Miller, S. L., 10 Apr 2017, In : Frontiers in Neuroscience. 11, APR, 12 p., 200.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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24 Citations (Scopus)