Hudson Institute - Department of Molecular and Translational Science

Research Output

2018

The role of MDA5 in the development of autoimmune disease

Sadler, A. J., 1 Feb 2018, In : Journal of leukocyte biology. 103, 2, p. 185-192 8 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

2 Citations (Scopus)

The STK35 locus contributes to normal gametogenesis and encodes a lncRNA responsive to oxidative stress

Miyamoto, Y., Whiley, P. A. F., Goh, H., Wong, C. L., Tachibana, T., McMenamin, P. G., Mayne, L. & Loveland, K. A. L., 1 Jan 2018, In : Biology Open. 7, 8, 12 p., bio032631.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53

Szczepny, A., Carey, K., McKenzie, L., Jayasekara, W. S. N., Rossello, F., Gonzalez-Rajal, A., McCaw, A. S., Popovski, D., Wang, D., Sadler, A. J., Mahar, A., Russell, P. A., Wright, G., McCloy, R. A., Garama, D. J., Gough, D. J., Baylin, S. B., Burgess, A., Cain, J. E. & Watkins, D. N., 25 Jan 2018, In : Oncogene. 37, p. 1939-1948 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

The use of CRISPR/Cas9 gene editing to confirm congenic contaminations in host-pathogen interaction studies

Ferrand, J., Croft, N. P., Pépin, G., Diener, K. R., Wu, D., Mangan, N. E., Pedersen, J., Behlke, M. A., Hayball, J. D., Purcell, A. W., Ferrero, R. L. & Gantier, M. P., 19 Mar 2018, In : Frontiers in Cellular and Infection Microbiology. 8, 10 p., 87.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Timeless Is a Novel Estrogen Receptor Co-activator Involved in Multiple Signaling Pathways in MCF-7 Cells

Magne Nde, C. B., Casas Gimeno, G., Docanto, M., Knower, K. C., Young, M. J., Buehn, J., Sayed, E. & Clyne, C. D., 11 May 2018, In : Journal of Molecular Biology. 430, 10, p. 1531-1543 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Tissue processing for stereological analyses of lung structure in chronic obstructive pulmonary disease

Saad, M. & Ruwanpura, S. M., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). USA: Humana Press, p. 155-162 8 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

Trawler Web: An online de novo motif discovery tool for next-generation sequencing datasets

Dang, L. T., Tondl, M., Chiu, M. H. H., Revote, J., Paten, B., Tano, V., Tokolyi, A., Besse, F., Quaife-Ryan, G., Cumming, H., Drvodelic, M. J., Eichenlaub, M. P., Hallab, J. C., Stolper, J. S., Rossello, F. J., Bogoyevitch, M. A., Jans, D. A., Nim, H. T., Porrello, E. R., Hudson, J. E. & 1 others, Ramialison, M., 5 Apr 2018, In : BMC Genomics. 19, 1, 9 p., 238.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Twin-to-twin transfusion syndrome neurodevelopmental follow-up study (neurodevelopmental outcomes for children whose twin-to-twin transfusion syndrome was treated with placental laser photocoagulation)

Bolch, C., Fahey, M., Reddihough, D., Williams, K., Reid, S., Guzys, A., Cole, S., Edwards, A., Fung, A., Hodges, R., Palma-Dias, R., Teoh, M. & Walker, S., 1 Aug 2018, In : BMC Pediatrics. 18, 1, 11 p., 256.

Research output: Contribution to journalArticleOtherpeer-review

Open Access
3 Citations (Scopus)

Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection

Richardson, A. M., Lewis, D. P., Kita, B., Ludlow, H., Groome, N. P., Hedger, M. P., de Kretser, D. M. & Lidbury, B. A., 12 Apr 2018, In : Journal of Translational Medicine. 16, 1, 11 p., 97.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Zoonotic transfer of Clostridium difficile harboring antimicrobial resistance between farm animals and humans

Knetsch, C. W., Kumar, N., Forster, S. C., Connor, T. R., Browne, H. P., Harmanus, C., Sanders, I. M., Harris, S. R., Turner, L., Morris, T., Perry, M., Miyajima, F., Roberts, P., Pirmohamed, M., Songer, J. G., Weese, J. S., Indra, A., Corver, J., Rupnik, M., Wren, B. W. & 3 others, Riley, T. V., Kuijper, E. J. & Lawley, T. D., 1 Mar 2018, In : Journal of Clinical Microbiology. 56, 3, 8 p., e01384-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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32 Citations (Scopus)
2017

(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease

Ying, L., Yan, F., Zhao, Y., Gao, H., Williams, B. R. G., Hu, Y., Li, X., Tian, R., Xu, P. & Wang, Y., 1 Dec 2017, In : Clinical and Experimental Pharmacology and Physiology. 44, 12, p. 1180-1191 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor null mice: Informing cell-type-specific roles

Cole, T. J. & Young, M. J., 1 Jul 2017, In : Journal of Endocrinology. 234, 1, p. T83-T92 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Abnormal vocal cord movement in patients with and without airway obstruction and asthma symptoms

Low, K., Ruane, L., Uddin, N., Finlay, P., Lau, K. K., Hamza, K., Holmes, P. W., Hamilton, G. & Bardin, P. G., 1 Feb 2017, In : Clinical & Experimental Allergy. 47, 2, p. 200-207 8 p.

Research output: Contribution to journalArticleOtherpeer-review

17 Citations (Scopus)

Activation of cGAS-dependent antiviral responses by DNA intercalating agents

Pepin, G., Nejad, C., Thomas, B. J., Ferrand, J., McArthur, K., Bardin, P. G., Williams, B. R. G. & Gantier, M. P., 9 Jan 2017, In : Nucleic Acids Research. 45, 1, p. 198-205 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Activin B is a novel biomarker for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) diagnosis: A cross sectional study

Lidbury, B. A., Kita, B., Lewis, D. P., Hayward, S., Ludlow, H., Hedger, M. P. & de Kretser, D. M., 16 Mar 2017, In : Journal of Translational Medicine. 15, 1, 10 p., 60.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling

de Weerd, N. A., Matthews, A. Y., Pattie, P. R., Bourke, N. M., Lim, S. S., Vivian, J. P., Rossjohn, J. & Hertzog, P. J., 5 May 2017, In : Journal of Biological Chemistry. 292, 18, p. 7554-7565 13 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Allergic adverse events following 2015 seasonal influenza vaccine, Victoria, Australia

Clothier, H. J., Crawford, N. W., Russell, M. A. & Buttery, J. P., 18 May 2017, In : Eurosurveillance. 22, 20, p. 1-7 7 p., 30535.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Altered SOX9 genital tubercle enhancer region in hypospadias

Sreenivasan, R., Gordon, C. T., Benko, S., de Iongh, R., Bagheri-Fam, S., Lyonnet, S. & Harley, V., Jun 2017, In : Journal of Steroid Biochemistry and Molecular Biology. 170, p. 28-38 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

An emergence framework of carcinogenesis

Sigston, E. A. W. & Williams, B. R. G., 14 Sep 2017, In : Frontiers in Oncology. 7, SEP, 14 p., 198.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

An in vitro model demonstrates the potential of neoplastic human germ cells to influence the tumour microenvironment

Klein, B., Schuppe, H. -C., Bergmann, M., Hedger, M. P., Loveland, B. E. & Loveland, K. L., Jul 2017, In : Andrology. 5, 4, p. 763-770 8 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

A non-canonical function of Ezh2 preserves immune homeostasis

Vasanthakumar, A., Xu, D., Lun, A. T. L., Kueh, A. J., van Gisbergen, K. P. J. M., Iannarella, N., Li, X., Yu, L., Wang, D., Williams, B. RG., Lee, S. C. W., Majewski, I. J., Godfrey, D. I., Smyth, G. K., Alexander, W. S., Herold, M. J., Kallies, A., Nutt, S. L. & Allan, R. S., 1 Apr 2017, In : EMBO Reports. 18, 4, p. 619-631 13 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Assessing the off-target effects of miRNA inhibitors on innate immune toll-like receptors

Pepin, G., Ferrand, J. & Gantier, M. P., 2017, Drug Target miRNA: Methods and Protocols. Schmidt, M. F. (ed.). New York NY USA: Humana Press, Vol. 1517. p. 127-135 9 p. (Methods in Molecular Biology: Springer Protocols; vol. 1517).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

1 Citation (Scopus)

ATF3 repression of BCL-XL determines apoptotic sensitivity to HDAC inhibitors across tumor types

Chüeh, A. C., Tse, J. W. T., Dickinson, M., Ioannidis, P., Jenkins, L., Togel, L., Tan, B. S., Luk, I., Davalos-Salas, M., Nightingale, R., Thompson, M. R., Williams, B. R. G., Lessene, G., Lee, E. F., Fairlie, W. D., Dhillon, A. S. & Mariadason, J. M., 15 Sep 2017, In : Clinical Cancer Research. 23, 18, p. 5573-5584 12 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Automatic segmentation of fetal brain using diffusion-weighted imaging cues

Shishegar, R., Joshi, A. A., Tolcos, M., Walker, D. W. & Johnston, L. A., 19 Jun 2017, IEEE International Symposium on Biomedical Imaging. IEEE, Institute of Electrical and Electronics Engineers, p. 804-807 4 p. 7950640

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Auto-phosphorylation represses protein kinase R activity

Wang, D., De Weerd, N. A., Willard, B., Polekhina, G., Williams, B. R. G. & Sadler, A. J., 10 Mar 2017, In : Scientific Reports. 7, 15 p., 44340.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Bacterial membrane vesicles transport their DNA cargo into host cells

Bitto, N. J., Chapman, R., Pidot, S., Costin, A., Lo, C., Choi, J., D'Cruze, T., Reynolds, E. C., Dashper, S. G., Turnbull, L., Whitchurch, C. B., Stinear, T. P., Stacey, K. J. & Ferrero, R. L., 1 Dec 2017, In : Scientific Reports. 7, 1, 11 p., 7072.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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41 Citations (Scopus)

Blockade of the IL-6 trans-signalling/STAT3 axis suppresses cachexia in Kras-induced lung adenocarcinoma

Miller, A., McLeod, L., Alhayyani, S., Szczepny, A., Watkins, D. N., Chen, W., Enriori, P., Ferlin, W., Ruwanpura, S. & Jenkins, B. J., 25 May 2017, In : Oncogene. 36, 21, p. 3059-3066 8 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Cattle phenotypes can disguise their maternal ancestry

Srirattana, K., McCosker, K., Schatz, T. & St. John, J. C., 26 Jun 2017, In : BMC Genetics. 18, 1, 59.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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9 Citations (Scopus)

cGAS-STING activation in the tumor microenvironment and its role in cancer immunity

Pépin, G. & Gantier, M. P., 2017, Regulation of Inflammatory Signaling in Health and Disease. Xu, D. (ed.). Singapore: Springer, p. 175-194 20 p. (Advances in Experimental Medicine and Biology; vol. 1024).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

15 Citations (Scopus)

Challenges and opportunities for siRNA-based cancer treatment

Wang, T., Shigdar, S., Shamaileh, H. A., Gantier, M. P., Yin, W., Xiang, D., Wang, L., Zhou, S. F., Hou, Y., Wang, P., Zhang, W., Pu, C. & Duan, W., 28 Feb 2017, In : Cancer Letters. 387, p. 77-83 7 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

36 Citations (Scopus)

Chondroitin sulfate proteoglycan protein is stimulated by interleukin 11 and promotes endometrial epithelial cancer cell proliferation and migration

Winship, A., Van Sinderen, M., Heffernan-Marks, A. & Dimitriadis, E., 1 Mar 2017, In : International journal of oncology. 50, 3, p. 798-804 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Combining hiPSCs and Human Genetics: Major Applications in Drug Development

Zhang, J., Li, H., Trounson, A., Wu, J. C. & Nioi, P., 3 Aug 2017, In : Cell Stem Cell. 21, 2, p. 161-165 5 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

10 Citations (Scopus)

Controversies and conundrums in vocal cord dysfunction

Bardin, P. G., Low, K., Ruane, L. & Lau, K. K., 1 Jul 2017, In : The Lancet Respiratory Medicine. 5, 7, p. 546-548 3 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

13 Citations (Scopus)

Coregulators as mediators of mineralocorticoid receptor signalling diversity

Fuller, P. J., Yang, J. & Young, M. J., 1 Jul 2017, In : Journal of Endocrinology. 234, 1, p. T23-T34 12 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

17 Citations (Scopus)

Correlation between diffusion tensor imaging and histological brain injury in ventilated preterm lambs

Alahmari, D. M., Barton, S. K., Galinsky, R., Nitsos, I., Atik, A. A., Farrell, M. J., Pearson, J. T. & Polglase, G. R., 2017, In : Imaging in Medicine. 9, 3, p. 67-76 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Costs of IVF in Australia: Downward trends shall continue

Trounson, A. & Hammarberg, K., 11 Sep 2017, BioNews.

Research output: Other contributionOther

Open Access

Cranial Pilocytic Astrocytoma With Spinal Drop Metastasis in an Adult: Case Report and Literature Review

Munshey, A., Moore, J. M., Maclean, C., Longano, A. & Goldschlager, T., 1 Feb 2017, In : World Neurosurgery. 98, p. 883.e7-883.e12 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

4 Citations (Scopus)

Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma

Greenall, S. A., Lim, Y. C., Mitchell, C. B., Ensbey, K. S., Stringer, B. W., Wilding, A. L., O'Neill, G. M., McDonald, K. L., Gough, D. J., Day, B. W. & Johns, T. G., 1 Jan 2017, In : Oncogenesis. 6, 5, 13 p., e336.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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25 Citations (Scopus)

Cytokines in male fertility and reproductive pathologies: Immunoregulation and beyond

Loveland, K. L., Klein, B., Pueschl, D., Indumathy, S., Bergmann, M., Loveland, B. E., Hedger, M. P. & Schuppe, H-C., 20 Nov 2017, In : Frontiers in Endocrinology. 8, NOV, 16 p., 307.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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28 Citations (Scopus)

Defining T helper cell immunity in bronchopulmonary dysplasia

Lao, J. C., Pang, M. A., Malhotra, A., Tan, K., Beker, F., Konig, K., Collins, C., Theda, C., Kamlin, C. O., Yeomans, E., Elsayed, K., Noble, E., Walsh, G., Argus, B., Twitchell, E., Berger, P., Veldman, A., Nold-Petry, C. A. & Nold, M. F., 1 May 2017, p. 125-126. 1 p.

Research output: Contribution to conferenceAbstract

Development and Biological Evaluation of a Photoactivatable Small Molecule Microtubule-Targeting Agent

Döbber, A., Phoa, A. F., Abbassi, R. H., Stringer, B. W., Day, B. W., Johns, T. G., Abadleh, M., Peifer, C. & Munoz, L., 13 Apr 2017, In : ACS Medicinal Chemistry Letters. 8, 4, p. 395-400 6 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Development of a health promotion programme to improve awareness of factors that affect fertility, and evaluation of its reach in the first 5 years

Hammarberg, K., Norman, R. J., Robertson, S., McLachlan, R., Michelmore, J. & Johnson, L., 1 Jun 2017, In : Reproductive Biomedicine & Society Online. 4, p. 33-40 8 p.

Research output: Contribution to journalComment / DebateResearchpeer-review

Open Access
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12 Citations (Scopus)

Development of a pipeline for automated, high-throughput analysis of paraspeckle proteins reveals specific roles for importin α proteins

Major, A. T., Miyamoto, Y., Lo, C. Y., Jans, D. A. & Loveland, K. L., 27 Feb 2017, In : Scientific Reports. 7, 18 p., 43323.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Dianthin-30 or gelonin versus monomethyl auristatin E, each configured with an anti-calcitonin receptor antibody, are differentially potent in vitro in high-grade glioma cell lines derived from glioblastoma

Gilabert-Oriol, R., Furness, S. G. B., Stringer, B. W., Weng, A., Fuchs, H., Day, B. W., Kourakis, A., Boyd, A. W., Hare, D. L., Thakur, M., Johns, T. G. & Wookey, P. J., 2017, In : Cancer Immunology Immunotherapy. 66, 9, p. 1217–1228 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Dimeric but not monomeric α-lactalbumin potentiates apoptosis by up regulation of ATF3 and reduction of histone deacetylase activity in primary and immortalised cells

Sharp, J. A., Brennan, A. J., Polekhina, G., Ascher, D. B., Lefevre, C. & Nicholas, K. R., 1 May 2017, In : Cellular Signalling. 33, p. 86-97 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Disruption of Serinc1, which facilitates serine-derived lipid synthesis, fails to alter macrophage function, lymphocyte proliferation or autoimmune disease susceptibility

Chu, E. P. F., Elso, C. M., Pollock, A. H., Alsayb, M. A., Mackin, L., Thomas, H. E., Kay, T. W. H., Silveira, P. A., Mansell, A. S., Gaus, K. & Brodnicki, T. C., 1 Feb 2017, In : Molecular Immunology. 82, p. 19-33 15 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Distinct Campylobacter fetus lineages adapted as livestock pathogens and human pathobionts in the intestinal microbiota

Iraola, G., Forster, S. C., Kumar, N., Lehours, P., Bekal, S., García-Peña, F. J., Paolicchi, F., Morsella, C., Hotzel, H., Hsueh, P. R., Vidal, A., Lévesque, S., Yamazaki, W., Balzan, C., Vargas, A., Piccirillo, A., Chaban, B., Hill, J. E., Betancor, L., Collado, L. & 8 others, Truyers, I., Midwinter, A. C., Dagi, H. T., Mégraud, F., Calleros, L., Pérez, R., Naya, H. & Lawley, T. D., 1 Dec 2017, In : Nature Communications. 8, 1, 8 p., 1367.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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14 Citations (Scopus)

Disturbed nitric oxide and homocysteine production are involved in the increased risk of cardiovascular diseases in the F1 offspring of maternal obesity and malnutrition

Moussa, Y. Y., Tawfik, S. H., Haiba, M. M., Saad, M. I., Hanafi, M. Y., Abdelkhalek, T. M., Oriquat, G. A. & Kamel, M. A., 1 Jun 2017, In : Journal of Endocrinological Investigation. 40, 6, p. 611-620 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)