Hudson Institute - Department of Molecular and Translational Science

Research Output

2018

In vivo infection model of severe influenza a virus

Mansell, A. & Tate, M. D., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. New York, NY: Humana Press, p. 91-99 9 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

3 Citations (Scopus)

Loss of maternal EED results in postnatal overgrowth

Prokopuk, L., Stringer, J. M., White, C. R., Vossen, R. H. A. M., White, S. J., Cohen, A. S. A., Gibson, W. T. & Western, P. S., 13 Jul 2018, In : Clinical Epigenetics. 10, 1, 14 p., 95.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility

Nguyen, Q. N., Zerafa, N., Liew, S. H., Morgan, F. H., Strasser, A., Scott, C. L., Findlay, J. K., Hickey, M. & Hutt, K. J., 1 Jun 2018, In : Cell Death and Disease. 9, 6, 12 p., 633.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
23 Citations (Scopus)

Loss of the Mitochondrial Fatty Acid β-Oxidation Protein Medium-Chain Acyl-Coenzyme A Dehydrogenase Disrupts Oxidative Phosphorylation Protein Complex Stability and Function

Lim, S. C., Tajika, M., Shimura, M., Carey, K. T., Stroud, D. A., Murayama, K., Ohtake, A. & McKenzie, M., 1 Dec 2018, In : Scientific Reports. 8, 1, 17 p., 153.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
15 Citations (Scopus)

Lung Diseases

Ruwanpura, S., Rosli, S. & Tate, M., 1 Jan 2018, Inflammasomes: Clinical and Therapeutic Implications. Cordero, M. D. & Alcocer-Gómez, E. (eds.). Cham, Switzerland: Springer, Vol. 108. p. 61-84 24 p. (Experientia Supplementum; vol. 108).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

2 Citations (Scopus)

Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation

Lang, T., Lee, J. P. W., Elgass, K., Pinar, A. A., Tate, M. D., Aitken, E. H., Fan, H., Creed, S. J., Deen, N. S., Traore, D. A. K., Mueller, I., Stanisic, D., Baiwog, F. S., Skene, C., Wilce, M. C. J., Mansell, A., Morand, E. F. & Harris, J., 1 Dec 2018, In : Nature Communications. 9, 1, 15 p., 2223.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
29 Citations (Scopus)

Measurement of oxidative stress: mitochondrial function using the seahorse system

Leung, D. T. H. & Chu, S., 1 Jan 2018, Preeclampsia: Methods and Protocols . Murthi, P. & Vaillancourt, C. (eds.). Humana Press, p. 285-293 9 p. (Methods in Molecular Biology; vol. 1710).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

Mechanisms and consequences of constitutive activation of integrin-linked kinase in acute myeloid leukemia

Alasseiri, M., Ahmed, A. U. & Williams, B. R. G., 1 Oct 2018, In : Cytokine and Growth Factor Reviews. 43, p. 1-7 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

2 Citations (Scopus)

Meeting summary: 2nd Aegean Conference on Cytokine Signaling in Cancer

Ilangumaran, S., Williams, B. R. G. & Kalvakolanu, D. V., Aug 2018, In : Cytokine. 108, p. 225-231 7 p.

Research output: Contribution to journalArticleOtherpeer-review

Melatonin improves endothelial function in vitro and prolongs pregnancy in women with early-onset preeclampsia

Hobson, S. R., Gurusinghe, S., Lim, R., Alers, N. O., Miller, S. L., Kingdom, J. C. & Wallace, E. M., 1 Oct 2018, In : Journal of Pineal Research. 65, 3, 14 p., e12508.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Menstruation and endometrial repair

Salamonsen, L. A. & Evans, J., 2018, Encyclopedia of Reproduction . Skinner, M. K. (ed.). 2nd ed. Academic Press, p. 320-325 6 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

Mesenchymal progenitor cells primed with pentosan polysulfate promote lumbar intervertebral disc regeneration in an ovine model of microdiscectomy

Daly, C. D., Ghosh, P., Zannettino, A. C. W., Badal, T., Shimmon, R., Jenkin, G., Oehme, D., Jain, K., Sher, I., Vais, A., Cohen, C., Chandra, R. V. & Goldschlager, T., 1 Mar 2018, In : The Spine Journal. 18, 3, p. 491-506 16 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

miR-222 isoforms are differentially regulated by type-I interferon

Nejad, C., Pillman, K. A., Siddle, K. J., Pépin, G., Anko, M. L., McCoy, C. E., Beilharz, T. H., Quintana-Murci, L., Goodall, G. J., Bracken, C. P. & Gantier, M. P., 1 Mar 2018, In : RNA. 24, 3, p. 332-341 10 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Moderate preterm birth affects right ventricular structure and function and pulmonary artery blood flow in adult sheep

Mrocki, M. M., Nguyen, V. B., Lombardo, P., Sutherland, M. R., Bensley, J. G., Nitsos, I., Allison, B. J., Harding, R., De Matteo, R., Schneider, M., Polglase, G. R. & Black, M. J., 1 Dec 2018, In : Journal of Physiology. 596, 23, p. 5965-5975 11 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Modified polyadenylation-based RT-qPCR increases selectivity of amplification of 3'-MicroRNA isoforms

Nejad, C., Pépin, G., Behlke, M. A. & Gantier, M. P., 24 Jan 2018, In : Frontiers in Genetics. 9, JAN, 9 p., 11.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Molybdenum cofactor deficiency type A: Prenatal monitoring using MRI

Lubout, C. M. A., Derks, T. G. J., Meiners, L., Erwich, J. J., Bergman, K. A., Lunsing, R. J., Schwarz, G., Veldman, A. & van Spronsen, F. J., 1 May 2018, In : European Journal of Paediatric Neurology. 22, 3, p. 536-540 5 p.

Research output: Contribution to journalArticleOtherpeer-review

3 Citations (Scopus)

Mouse double minute homologue 2 (MDM2) downregulation by miR-661 impairs human endometrial epithelial cell adhesive capacity

Winship, A., Ton, A., Van Sinderen, M., Menkhorst, E., Rainczuk, K., Griffiths, M., Cuman, C. & Dimitriadis, E., 1 Jan 2018, In : Reproduction, Fertility and Development. 30, 3, p. 477-486 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Mutant NR5A1/SF-1 in patients with disorders of sex development shows defective activation of the SOX9 TESCO enhancer

Sreenivasan, R., Ludbrook, L. M., Fisher, B. D., Declosmenil, F., Knower, K. C., Croft, B. M., Bird, A. D., Ryan, J., Bashamboo, A., Sinclair, A., Koopman, P., McElreavey, K., Poulat, F. & Harley, V. R., 1 Dec 2018, In : Human Mutation. 39, 12, p. 1861-1874 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

New Trends in Anti-Cancer Therapy: Combining Conventional Chemotherapeutics with Novel Immunomodulators

Wilson, A. L., Plebanski, M. & Stephens, A. N., 2018, In : Current Medicinal Chemistry. 25, 36, p. 4758-4784 27 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

7 Citations (Scopus)

NOD1 is required for Helicobacter pylori induction of IL-33 responses in gastric epithelial cells

Tran, L. S., Tran, D., De Paoli, A., D'Costa, K., Creed, S. J., Ng, G. Z., Le, L., Sutton, P., Silke, J., Nachbur, U. & Ferrero, R. L., 1 May 2018, In : Cellular Microbiology. 20, 5, 12 p., e12826.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Obesity associated advanced glycation end products within the human uterine cavity adversely impact endometrial function and embryo implantation competence

Antoniotti, G. S., Coughlan, M., Salamonsen, L. A. & Evans, J., 1 Apr 2018, In : Human Reproduction. 33, 4, p. 654-665 12 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Optimization techniques for miRNA expression in low frequency immune cell populations

Lyons, V. G., Payne, N. L. & McCoy, C. E., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). New York, NY: Humana Press, p. 237-256 20 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Out of sight, out of mind? Germ cells and the potential impacts of epigenomic drugs [version 1; referees: 3 approved]

Jarred, E. G., Bildsoe, H. & Western, P. S., 1 Jan 2018, In : F1000Research. 7, 14 p., 1967.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
3 Citations (Scopus)

PD-L1 expression is a prognostic factor in subgroups of gastric cancer patients stratified according to their levels of CD8 and FOXP3 immune markers

Ying, L., Yan, F., Meng, Q., Yu, L., Yuan, X., Gantier, M. P., Williams, B. R. G., Chan, D. W., Shi, L., Tu, Y., Ni, P., Wang, X., Chen, W., Zang, X., Xu, D. & Hu, Y., 20 Feb 2018, In : OncoImmunology. 7, 6, 11 p., e1433520.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Pharmacological inhibition of EZH2 disrupts the female germline epigenome

Prokopuk, L., Hogg, K. & Western, P. S., 5 Mar 2018, In : Clinical Epigenetics. 10, 1, 12 p., 33.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
8 Citations (Scopus)

PLK1 has tumor-suppressive potential in APC-Truncated colon cancer cells

Raab, M., Sanhaji, M., Matthess, Y., Hörlin, A., Lorenz, I., Dötsch, C., Habbe, N., Waidmann, O., Kurunci-Csacsko, E., Firestein, R., Becker, S. & Strebhardt, K., 1 Dec 2018, In : Nature Communications. 9, 1, 17 p., 1106.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
9 Citations (Scopus)

Recent insights into targeting the IL-6 cytokine family in inflammatory diseases and cancer

Jones, S. A. & Jenkins, B. J., 1 Dec 2018, In : Nature Reviews Immunology. 18, 12, p. 773-789 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

74 Citations (Scopus)

Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance

Stringer, J., Forster, S., Qu, Z., Prokopuk, L. A., O'Bryan, M. K., Gardner, D. K., White, S., Adelson, D. L. & Western, P. S., 20 Sep 2018, In : BMC Biology. 16, 20 p., 104.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Regulatory landscape of the hox transcriptome

Casaca, A. N. A., Hauswirth, G. M., Bildsoe, H., Mallo, M. & McGlinn, E., 1 Jan 2018, In : International Journal of Developmental Biology. 62, 11-12, p. 693-704 12 p., 62.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Role of activin A in the pathogenesis of endothelial cell dysfunction in preeclampsia

Hobson, S. R., Lim, R., Mockler, J. C., Gurusinghe, S. & Wallace, E. M., 2018, Methods in Molecular Biology. Murthi, P. & Vaillancourt, C. (eds.). New York, NY: Humana Press, p. 39-52 14 p. (Methods in Molecular Biology; vol. 1710).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Serum podocalyxin for early detection of preeclampsia at 11–13 weeks of gestation

Mansilla, M. K. S., Wang, Y., Hyett, J., da Silva Costa, F. & Nie, G., 1 Nov 2018, In : Placenta. 71, p. 13-15 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Setting up a primary aldosteronism program: an Australian experience

Yang, J. & Funder, J. W., Jun 2018, In : Chinese Journal of Endocrinology and Metabolism. 34, 6, p. 451-459 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters

Jansz, N., Keniry, A., Trussart, M., Bildsoe, H., Beck, T., Tonks, I. D., Mould, A. W., Hickey, P., Breslin, K., Iminitoff, M., Ritchie, M. E., McGlinn, E., Kay, G. F., Murphy, J. M. & Blewitt, M. E., 1 Sep 2018, In : Nature Structural & Molecular Biology. 25, 9, p. 766-777 12 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Spermiation

O'Donnell, L. & Stanton, P., 2018, Encyclopedia of Reproduction. Skinner, M. K. (ed.). 2nd ed. Academic Press, Vol. 1. p. 145-151 6 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

Sperm protein 17 expression by murine epithelial ovarian cancer cells and its impact on tumor progression

Gao, Q., Xiang, S. D., Wilson, K., Madondo, M., Stephens, A. N. & Plebanski, M., 20 Aug 2018, In : Cancers. 10, 8, 15 p., 276.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

STAT3: a multifaceted oncoprotein

Guanizo, A. C., Fernando, C. D., Garama, D. J. & Gough, D. J., 4 Mar 2018, In : Growth Factors. 36, 1-2, p. 1-14 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

14 Citations (Scopus)

Structure/Cells Overview

de Kretser, D., Stanton, P. & O'Donnell, L., 2018, Encyclopedia of Reproduction. Skinner, M. K. (ed.). 2nd ed. Elsevier, Vol. 1. p. 10-16 7 p.

Research output: Chapter in Book/Report/Conference proceedingEncyclopaedia / Dictionary EntryOtherpeer-review

Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL

Schuelein, R., Spencer, H., Dagley, L. F., Li, P., Luo, L., Stow, J. L., Abraham, G. C., Naderer, T., Gomez-Valero, L., Buchrieser, C., Sugimoto, C., Yamagishi, J., Webb, A. I., Pasricha, S. & Hartland, E. L., 1 Sep 2018, In : Cellular Microbiology. 20, 9, 44 p., e12852.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Testicular Cancer in Relation to Testicular Dysgenesis Syndrome

Loveland, K. L., Rajpert-De Meyts, E. & Veeramachaneni, D. N. R., 2018, Comprehensive Toxicology. McQueen, C. A. (ed.). 3rd ed. Netherlands: Elsevier, Vol. 4. p. 147-164 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

The association of mitochondrial DNA haplotypes and phenotypic traits in pigs

St John, J. C. & Tsai, T. S., 6 Jul 2018, In : BMC Genetics. 19, 1, 12 p., 41.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma

Sun, X., Vaghjiani, V., Jayasekara, W. S. N., Cain, J. E. & St John, J. C., 17 Dec 2018, In : Clinical Epigenetics. 10, 1, 17 p., 157.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)
4 Citations (Scopus)

The endometrial polarity paradox: Differential regulation of polarity within secretory-Phase human endometrium

Whitby, S., Salamonsen, L. A. & Evans, J., 1 Jan 2018, In : Endocrinology. 159, 1, p. 506-518 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

The evolutionary pattern of mutations in glioblastoma reveals therapy-mediated selection

Muscat, A. M., Wong, N. C., Drummond, K. J., Algar, E. M., Khasraw, M., Verhaak, R., Field, K., Rosenthal, M. A. & Ashley, D. M., 1 Jan 2018, In : Oncotarget. 9, 8, p. 7844-7858 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

The impact of sleep disordered breathing on cardiovascular health in overweight children

Horne, R. SC., Shandler, G., Tamanyan, K., Weichard, A. J., Odoi, A., Biggs, S. N., Davey, M., Nixon, G. M. & Walter, L. M., 1 Jan 2018, In : Sleep Medicine. 41, p. 58-68 11 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1β Activation

Vince, J. E., De Nardo, D., Gao, W., Vince, A. J., Hall, C., McArthur, K., Simpson, D., Vijayaraj, S., Lindqvist, L. M., Bouillet, P., Rizzacasa, M. A., Man, S. M., Silke, J., Masters, S. L., Lessene, G., Huang, D. C. S., Gray, D. H. D., Kile, B. T., Shao, F. & Lawlor, K. E., 27 Nov 2018, In : Cell Reports. 25, 9, p. 2339-2353 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
33 Citations (Scopus)

The mitochondrial genome: How it drives fertility

St John, J. C., Srirattana, K., Tsai, T. S. & Sun, X., 1 Jan 2018, In : Reproduction, Fertility and Development. 30, 1, p. 118-139 22 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The molecular characterisation of mitochondrial DNA deficient oocytes using a pig model

Tsai, T. S., Tyagi, S. & St John, J. C., 1 May 2018, In : Human Reproduction. 33, 5, p. 942-953 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The Role of Copy Number Variants in Disorders of Sex Development

Croft, B., Ohnesorg, T. & Sinclair, A. H., 1 Feb 2018, In : Sexual Development. 12, 1-3, p. 19-29 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

13 Citations (Scopus)