Hudson Institute - Department of Molecular and Translational Science

Research Output

2018

A guide to miRNAs in inflammation and innate immune responses

Nejad, C., Stunden, H. J. & Gantier, M. P., 24 Apr 2018, In : FEBS Journal. 285, 20, p. 3695-3716 22 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

An anti-gdnf family receptor alpha 1 (gfra1 antibody–drug conjugate for the treatment of hormone receptor–positive breast cancer

Bhakta, S., Crocker, L. M., Chen, Y., Hazen, M., Schutten, M. M., Li, D., Kuijl, C., Ohri, R., Zhong, F., Poon, K. A., Go, M. A. T., Cheng, E., Piskol, R., Firestein, R., Fourie-O'Donohue, A., Kozak, K. R., Raab, H., Hongo, J. A., Sampath, D., Dennis, M. S. & 3 others, Scheller, R. H., Polakis, P. & Junutula, J. R., 1 Mar 2018, In : Molecular Cancer Therapeutics. 17, 3, p. 638-649 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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14 Citations (Scopus)

An update on the NLRP3 inflammasome and influenza: the road to redemption or perdition?

Tate, M. D. & Mansell, A., 1 Jul 2018, In : Current Opinion in Immunology. 54, p. 80-85 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

8 Citations (Scopus)

A phase IIa study of HA-irinotecan, formulation of hyaluronic acid and irinotecan targeting CD44 in extensive-stage small cell lung cancer

Alamgeer, M., Neil Watkins, D., Banakh, I., Kumar, B., Gough, D. J., Markman, B. & Ganju, V., 1 Apr 2018, In : Investigational New Drugs. 36, 2, p. 288-298 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

A Pre-Clinical Assessment of the Pan-ERBB Inhibitor Dacomitinib in Pediatric and Adult Brain Tumors

Endersby, R., Whitehouse, J., Hii, H., Greenall, S. A., Johns, T. G. & Gottardo, N. G., 1 May 2018, In : Neoplasia. 20, 5, p. 432-442 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Assessing the cGAS-cGAMP-STING activity of cancer cells

Pépin, G. & Gantier, M. P., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). New York, NY: Humana Press, p. 257-266 10 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)
3 Citations (Scopus)

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands

Faridi, P., Li, C., Ramarathinam, S. H., Vivian, J. P., Illing, P. T., Mifsud, N. A., Ayala, R., Song, J., Gearing, L. J., Hertzog, P. J., Ternette, N., Rossjohn, J., Croft, N. P. & Purcell, A. W., 12 Oct 2018, In : Science Immunology. 3, 28, 12 p., eaar3947.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Autoantibodies against HSF1 and CCDC155 as biomarkers of early-Stage, high-Grade serous ovarian cancer

Wilson, A. L., Moffitt, L. R., Duffield, N., Rainczuk, A., Jobling, T. W., Plebanski, M. & Stephens, A. N., 1 Feb 2018, In : Cancer Epidemiology Biomarkers and Prevention. 27, 2, p. 183-192 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Being born too small and too early may alter sleep in childhood

Yiallourou, S. R., Arena, B. C., Wallace, E. M., Odoi, A., Hollis, S., Weichard, A. & Horne, R. S. C., 1 Feb 2018, In : Sleep. 41, 2, 11 p., zsx193.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Carotenoid composition of a New Zealand (Evechinus chloroticus) and an Australian (Heliocidaris erythrogramma) sea urchin in relation to gonad colour

Brewster, J., Garama, D., Lamare, M. & Carne, A., 1 Aug 2018, In : Aquaculture Research. 49, 8, p. 2751-2762 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Citrobacter rodentium infection model for the analysis of bacterial pathogenesis and mucosal immunology

Kennedy, C. L. & Hartland, E. L., 2018, Methods in Molecular Biology. Jenkins, B. J. (ed.). New York, NY: Humana Press, p. 77-89 13 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

2 Citations (Scopus)

Clinical utility of a STAT3-regulated miRNA-200 family signature with prognostic potential in early gastric cancer

Yu, L., Wu, D., Gao, H., Balic, J. J., Tsykin, A., Han, T. S., Liu, Y. D., Kennedy, C. L., Li, J. K., Mao, J. Q., Tan, P., Oshima, M., Goodall, G. J. & Jenkins, B. J., 15 Mar 2018, In : Clinical Cancer Research. 24, 6, p. 1459-1472 14 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Commensal Koch's postulates: establishing causation in human microbiota research

Neville, B. A., Forster, S. C. & Lawley, T. D., 1 Apr 2018, In : Current Opinion in Microbiology. 42, p. 47-52 6 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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30 Citations (Scopus)

Concurrent host-pathogen transcriptional responses in a clostridium perfringens murine myonecrosis infection

Low, L-Y., Harrison, P. F., Gould, J., Powell, D. R., Choo, J. M., Forster, S. C., Chapman, R., Gearing, L. J., Cheung, J. K., Hertzog, P. & Rood, J. I., 1 Mar 2018, In : mBio. 9, 2, 15 p., e00473-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Controlling the Effective Oxygen Tension Experienced by Cells Using a Dynamic Culture Technique for Hematopoietic Ex Vivo Expansion

Tiwari, A., Wong, C., Nekkanti, L. P., Deane, J. A., McDonald, C., Li, J., Pham, Y., Sutherland, A. E., Jenkin, G. & Kirkland, M., 28 Feb 2018, In : Current Protocols in Stem Cell Biology. 44, 1, p. 2A.11.1-2A.11.13 13 p.

Research output: Contribution to journalArticleOtherpeer-review

Culturing of female bladder bacteria reveals an interconnected urogenital microbiota

Thomas-White, K., Forster, S. C., Kumar, N., Van Kuiken, M., Putonti, C., Stares, M. D., Hilt, E. E., Price, T. K., Wolfe, A. J. & Lawley, T. D., 1 Dec 2018, In : Nature Communications. 9, 1, 7 p., 1557.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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33 Citations (Scopus)

Cytoskeletons (F-actin) and spermatogenesis

O'Donnell, L. & Stanton, P., 2018, Spermatogenesis: Biology and Clinical Implications. Cheng, CY. (ed.). 1st ed. Boca Raton: Taylor & Francis, p. 191-200 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer

Leong, T. L., Gayevskiy, V., Steinfort, D. P., De Massy, M. R., Gonzalez-Rajal, A., Marini, K. D., Stone, E., Chin, V., Havryk, A., Plit, M., Irving, L. B., Jennings, B. R., McCloy, R. A., Jayasekara, W. S. N., Alamgeer, M., Boolell, V., Field, A., Russell, P. A., Kumar, B., Gough, D. J. & 8 others, Szczepny, A., Ganju, V., Rossello, F. J., Cain, J. E., Papenfuss, A. T., Asselin-Labat, M. L., Cowley, M. J. & Watkins, D. N., 7 Mar 2018, In : Oncogene. 38, 10, p. 1661-1675 15 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Defining the distinct, intrinsic properties of the novel type i interferon, IFNϵ

Stifter, S. A., Matthews, A. Y., Mangan, N. E., Fung, K. Y., Drew, A., Tate, M. D., Soares Da Costa, T. P., Hampsey, D., Mayall, J., Hansbro, P. M., Minambres, A. G., Eid, S. G., Mak, J., Scoble, J., Lovrecz, G., DeWeerd, N. A. & Hertzog, P. J., 1 Jan 2018, In : Journal of Biological Chemistry. 293, 9, p. 3168-3179 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Diabetes-induced hyperglycemia impairs male reproductive function: A systematic review

Maresch, C. C., Stute, D. C., Alves, M. G., Oliveira, P. F., de Kretser, D. M. & Linn, T., 1 Jan 2018, In : Human Reproduction Update. 24, 1, p. 86-105 20 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

40 Citations (Scopus)

Differential expression profiles of conserved Snail transcription factors in the mouse testis

Micati, D. J., Hime, G. R., McLaughlin, E. A., Abud, H. E. & Loveland, K. L., 1 Mar 2018, In : Andrology. 6, 2, p. 362-373 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

Greenall, S. A., Donoghue, J., Johns, T. G. & Adams, T. E., 1 Aug 2018, In : Translational Oncology. 11, 4, p. 971-978 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine

Sandow, J. J., Rainczuk, A., Infusini, G., Makanji, M., Bilandzic, M., Wilson, A. L., Fairweather, N., Stanton, P. G., Garama, D., Gough, D., Jobling, T. W., Webb, A. I. & Stephens, A. N., 1 May 2018, In : Proteomics - Clinical Applications. 12, 3, 10 p., 1700135.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Dysregulation and dislocation of SFPQ disturbed DNA organization in Alzheimer's disease and frontotemporal dementia

Lu, J., Shu, R. & Zhu, Y., 23 Jan 2018, In : Journal of Alzheimer's Disease. 61, 4, p. 1311-1321 11 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Editorial: Biology and pathogenesis of Legionella

Newton, H. J., Hartland, E. L. & MacHner, M. P., 19 Sep 2018, In : Frontiers in Cellular and Infection Microbiology. 8, SEP, 3 p., 328.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access

Epigenomic drugs and the germline: Collateral damage in the home of heritability?

Western, P. S., 15 Jun 2018, In : Molecular and Cellular Endocrinology. 468, p. 121-133 13 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Erratum: Author Correction: Transcriptional dysregulation of Interferome in experimental and human Multiple Sclerosis (Scientific reports (2017) 7 1 (8981))

Srinivasan, S., Severa, M., Rizzo, F., Menon, R., Brini, E., Mechelli, R., Martinelli, V., Hertzog, P., Salvetti, M., Furlan, R., Martino, G., Comi, G., Coccia, E. M. & Farina, C., 11 May 2018, In : Scientific Reports. 8, 1, 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Esrp1 is a marker of mouse fetal germ cells and differentially expressed during spermatogenesis

Saeidi, S., Shapouri, F., De Iongh, R. U., Casagranda, F., Sutherland, J. M., Western, P. S., McLaughlin, E. A., Familari, M. & Hime, G. R., 1 Jan 2018, In : PLoS ONE. 13, 1, 15 p., e0190925.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Extracellular vesicles in human reproduction in health and disease

Simon, C., Greening, D. W., Balaguer, N., Salamonsen, LA. & Vilella, F., Jun 2018, In : Endocrine Reviews. 39, 3, p. 292-332 41 p.

Research output: Contribution to journalArticleOtherpeer-review

Formyl peptide receptor-2 is decreased in foetal growth restriction and contributes to placental dysfunction

Lappas, M., McCracken, S., McKelvey, K., Lim, R., James, J., Roberts, C. T., Fournier, T., Alfaidy, N., Powell, K. L., Borg, A. J., Morris, J. M., Leaw, B., Singh, H., Ebeling, P. R., Wallace, E. M., Parry, L. J., Dimitriadis, E. & Murthi, P., 1 Feb 2018, In : Molecular Human Reproduction. 24, 2, p. 94-109 16 p., gax067.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Galectin‑7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration

Menkhorst, E., Griffiths, M., van Sinderen, M., Rainczuk, K., Niven, K. & Dimitriadis, E., 1 Oct 2018, In : Oncology Letters. 16, 4, p. 4721-4728 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Genetic variation affecting DNA methylation and the human imprinting disorder, Beckwith-Wiedemann syndrome

Dagar, V., Hutchison, W., Muscat, A., Krishnan, A., Hoke, D., Buckle, A., Siswara, P., Amor, D. J., Mann, J., Pinner, J., Colley, A., Wilson, M., Sachdev, R., McGillivray, G., Edwards, M., Kirk, E., Collins, F., Jones, K., Taylor, J., Hayes, I. & 14 others, Thompson, E., Barnett, C., Haan, E., Freckmann, M-L., Turner, A., White, S., Kamien, B., Ma, A., Mackenzie, F., Baynam, G., Kiraly-Borri, C., Field, M., Dudding-Byth, T. & Algar, E., 30 Aug 2018, In : Clinical Epigenetics. 10, 1, 13 p., 114.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Haemodynamic effects of umbilical cord milking in premature sheep during the neonatal transition

Blank, D. A., Polglase, G. R., Kluckow, M., Gill, A. W., Crossley, K. J., Moxham, A., Rodgers, K., Zahra, V., Inocencio, I., Stenning, F., Larosa, D. A., Davis, P. G. & Hooper, S. B., 1 Nov 2018, In : Archives of Disease in Childhood: Fetal and Neonatal Edition. 103, 6, p. F539-F546 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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29 Citations (Scopus)

Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing

Lim, C. H., Sun, Q., Ratti, K., Lee, S. H., Zheng, Y., Takeo, M., Lee, W., Rabbani, P., Plikus, M. V., Cain, J. E., Wang, D. H., Watkins, D. N., Millar, S., Taketo, M. M., Myung, P., Cotsarelis, G. & Ito, M., 21 Nov 2018, In : Nature Communications. 9, 1, 13 p., 4903.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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18 Citations (Scopus)

Helicobacter pylori type IV secretion system and its adhesin subunit, CagL, mediate potent inflammatory responses in primary human endothelial cells

Tafreshi, M., Guan, J., Gorrell, R. J., Chew, N., Xin, V., Deswaerte, V., Rohde, M., Daly, R. J., Peek Jr, R. M., Jenkins, B. J., Davies, E. M. & Kwok, T., 6 Feb 2018, In : Frontiers in Cellular and Infection Microbiology. 8, FEB, 15 p., 22.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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12 Citations (Scopus)

Hepatotoxicity after paracetamol overdose in a patient with cystic fibrosis despite early acetylcysteine and utility of microRNA to predict hepatotoxicity

Wong, A., Cheung, B., Nejad, C., Gantier, M. & Graudins, A., 3 Oct 2018, In : Clinical Toxicology. 56, 10, p. 904–906 3 p.

Research output: Contribution to journalArticleOtherpeer-review

2 Citations (Scopus)

Highly pathogenic avian H5N8 influenza viruses: should we be concerned?

Tate, M. D., 2018, In : Virulence. 9, 1, p. 1-2 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

2 Citations (Scopus)

HtrA3 Isoform-Specific ELISAs for Early Detection of Preeclampsia

Wang, Y., Li, Y., Hyett, J., Da Silva Costa, F. & Nie, G., 1 Dec 2018, In : SLAS Discovery. 23, 10, p. 1092-1099 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

Croft, B. M., Ohnesorg, T., Hewitt, J., Bowles, J., Quinn, A., Tan, J., Corbin, V. D. A., Pelosi, E., Van Den Bergen, J., Sreenivasan, R., Knarston, I. M., Robevska, G., Vu, D. C., Hutson, J., Harley, V., Ayers, K., Koopman, P. & Sinclair, A., 14 Dec 2018, In : Nature Communications. 9, 1, 10 p., 5319.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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22 Citations (Scopus)

Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development

Hill, D. G., Yu, L., Gao, H., Balic, J. J., West, A., Oshima, H., McLeod, L., Oshima, M., Gallimore, A., D'Costa, K., Bhathal, P. S., Sievert, W., Ferrero, R. L., Jenkins, B. J. & Jones, G. W., 1 Jul 2018, In : International Journal of Cancer. 143, 1, p. 167-178 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Hypoxia is involved in the reduction of HtrA3 in patients with endometrial hyperplasia and cancer

Lv, Q., Yang, B., Ning, C., Xie, B., Nie, G., Chen, X. & Chen, Q., 18 Sep 2018, In : Biochemical and Biophysical Research Communications. 503, 4, p. 2918-2923 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Immuno-detection of immature and bioactive forms of the inflammatory cytokine IL-18

Jenkins, B. J. & Deswaerte, V., 1 Jan 2018, Inflammation and Cancer: Methods and Protocols. Jenkins, B. J. (ed.). New York, NY: Humana Press, p. 229-235 7 p. (Methods in Molecular Biology; vol. 1725).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

Immunotherapeutic Interleukin-6 or Interleukin-6 Receptor Blockade in Cancer: Challenges and Opportunities

Kampan, N. C., Xiang, S. D., McNally, O. M., Stephens, A. N., Quinn, M. A. & Plebanski, M., 1 Jan 2018, In : Current Medicinal Chemistry. 25, 36, p. 4785-4806 22 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

13 Citations (Scopus)

Improving access to ART in low-income settings through knowledge transfer: a case study from Zimbabwe

Hammarberg, K., Trounson, A., McBain, J., Matthews, P., Robertson, T., Robertson, F., Magli, C., Mhlanga, T., Makurumure, T. & Marechera, F., 1 Sep 2018, In : Human Reproduction Open. 8, 4, p. 1-5 5 p., hoy017.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Increased prevalence of fracture and hypoglycaemia in young adults with concomitant type 1 diabetes mellitus and coeliac disease

Thong, E. P., Wong, P., Dev, A., Ebeling, P. R., Teede, H. J. & Milat, F., 1 Jan 2018, In : Clinical Endocrinology. 88, 1, p. 37-43 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Inflammasome adaptor ASC suppresses apoptosis of gastric cancer cells by an IL18-mediated inflammation-independent mechanism

Deswaerte, V., Nguyen, P., West, A., Browning, A. F., Yu, L., Ruwanpura, S. M., Balic, J., Livis, T., Girard, C., Preaudet, A., Oshima, H., Fung, K. Y., Tye, H., Najdovska, M., Ernst, M., Oshima, M., Gabay, C., Putoczki, T. & Jenkins, B. J., 1 Mar 2018, In : Cancer Research. 78, 5, p. 1293-1307 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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14 Citations (Scopus)

Interleukin 11 blockade during mid to late gestation does not affect maternal blood pressure, pregnancy viability or subsequent fertility in mice

Winship, A., Menkhorst, E., Van Sinderen, M. & Dimitriadis, E., 1 Mar 2018, In : Reproductive BioMedicine Online. 36, 3, p. 250-258 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Interleukin 11 is upregulated in preeclampsia and leads to inflammation and preeclampsia features in mice

Winship, A. & Dimitriadis, E., 1 Feb 2018, In : Journal of Reproductive Immunology. 125, p. 32-38 7 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

4 Citations (Scopus)

In vitro antioxidant activity of phenolic-enriched extracts from Zhangping Narcissus tea cake and their inhibition on growth and metastatic capacity of 4T1 murine breast cancer cells

Ying, L., Kong, D. D., Gao, Y. Y., Yan, F., Wang, Y. F. & Xu, P., 1 Mar 2018, In : Journal of Zhejiang University: Science B. 19, 3, p. 199-210 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)