Hudson Institute - Department of Molecular and Translational Science

Research Output

(-)-Epigallocatechin-3-gallate and atorvastatin treatment down-regulates liver fibrosis-related genes in non-alcoholic fatty liver disease

Ying, L., Yan, F., Zhao, Y., Gao, H., Williams, B. R. G., Hu, Y., Li, X., Tian, R., Xu, P. & Wang, Y., 1 Dec 2017, In : Clinical and Experimental Pharmacology and Physiology. 44, 12, p. 1180-1191 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

(−)-Epigallocatechin-3-gallate and EZH2 inhibitor GSK343 have similar inhibitory effects and mechanisms of action on colorectal cancer cells

Ying, L., Yan, F., Williams, B. R. G., Xu, P., Li, X., Zhao, Y., Hu, Y., Wang, Y., Xu, D. & Dai, J., 1 Jan 2018, In : Clinical and Experimental Pharmacology and Physiology. 45, 1, p. 58-67 10 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

11 Intragonadal control mechanisms

Findlay, J. K. & Risbridger, G. P., 1987, In : Bailliere's Clinical Endocrinology and Metabolism. 1, 1, p. 223-243 21 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

17beta-Estradiol induces apoptosis in the developing rodent prostate independently of ERalpha or ERbeta

Taylor, R. A., Cowin, P. A., Couse, J. F., Korach, K. S. & Risbridger, G. P., 2006, In : Endocrinology. 147, 1, p. 191 - 200 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

30 YEARS OF THE MINERALOCORTICOID RECEPTOR: Mineralocorticoid receptor null mice: Informing cell-type-specific roles

Cole, T. J. & Young, M. J., 1 Jul 2017, In : Journal of Endocrinology. 234, 1, p. T83-T92 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

5 Control of spermatogenesis by follicle stimulating hormone and testosterone

de Kretser, D. M., McLachlan, R. I., Robertson, D. M. & Wreford, N. G., 1992, In : Bailliere's Clinical Endocrinology and Metabolism. 6, 2, p. 335-354 20 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

5Inhibin-a non-steroidal regulator of pituitary follicle stimulating hormone

McLachlan, R. I., Robertson, D. M., de Kretser, D. & Burger, H. G., 1987, In : Bailliere's Clinical Endocrinology and Metabolism. 1, 1, p. 89-112 24 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

6 Mineralocorticoid resistance

Komesaroff, P. A., Funder, J. W. & Fuller, P. J., 1994, In : Bailliere's Clinical Endocrinology and Metabolism. 8, 2, p. 333-355 23 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

6 The physiology of testicular inhibin and related proteins

Robertson, D. M., Risbridger, G. P. & de Kretser, D. M., 1992, In : Bailliere's Clinical Endocrinology and Metabolism. 6, 2, p. 355-372 18 p.

Research output: Contribution to journalArticleOtherpeer-review

8 Citations (Scopus)

7 Humoral regulation of intestinal adaptation

Taylor, R. G. & Fuller, P. J., 1994, In : Bailliere's Clinical Endocrinology and Metabolism. 8, 1, p. 165-183 19 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

A 46,XY female DSD patient with bilateral gonadoblastoma, a novel SRY missense mutation combined with a WT1 KTS splice-site mutation

Hersmus, R., van der Zwan, Y., Stoop, H., Bernard, P., Sreenivasan, R., Oosterhuis, J. W., Bruggenworth, H. T., De Boer, C. M., White, S., Wolffenbuttel, K. P., Alders, M. A., McElreavy, K., Drop, S. L. S., Harley, V. R. & Looijenga, L. H., 2012, In : PLoS ONE. 7, 7, 8 p., e40858.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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18 Citations (Scopus)

A bedside assay to detect streptococcus pneumoniae in children with empyema

Strachan, R., Cornelius, A., Gilbert, G., Gulliver, T., Martin, A., McDonald, T., Nixon, G., Roseby, R., Ranganathan, S., Selvadurai, H., Smith, G., Soto-Martinez, M., Suresh, S., Teoh, L., Thapa, K., Wainwright, C. & Jaffe, A., 2011, In : Pediatric Pulmonology. 46, 2, p. 179 - 183 5 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Aberrant Activation of JAK/STAT Pathway Components in Response to G-CSF, Interferon-a/p and Interferon-y in NFS-60 Cells

Novak, U., Ward, A. C., Hertzog, P. J., Hamilton, J. A. & Paradiso, L., 1 Jan 1996, In : Growth Factors. 13, 42067, p. 251-260 10 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Aberrant epithelial-mesenchymal Hedgehog signaling characterizes Barrett's metaplasia

Wang, D. H., Clemons, N. J., Miyashita, T., Dupuy, A. J., Zhang, W., Szczepny, A., Corcoran-Schwartz, I. M., Wilburn, D. L., Montgomery, E. A., Wang, J. S., Jenkins, N. A., Copeland, N. A., Harmon, J. W., Phillips, W. A. & Watkins, D. N., 2010, In : Gastroenterology. 138, 5, p. 1810 - 1822.e2 15 p.

Research output: Contribution to journalArticleResearchpeer-review

120 Citations (Scopus)

Aberrant fibroblast growth factor receptor signaling in bladder and other cancers

Chaffer, C., Dopheide, B., Savagner, P., Thompson, E. W. & Williams, E., 2007, In : Differentiation. 75, 9, p. 831 - 842 12 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

Abnormal vocal cord function in difficult-to-treat asthma

Low, K., Lau, K., Holmes, P., Crossett, M., Vallance, N., Phyland, D., Hamza, K., Hamilton, G. & Bardin, P., 2011, In : American Journal of Respiratory and Critical Care Medicine. 184, 1, p. 50 - 56 7 p.

Research output: Contribution to journalArticleResearchpeer-review

79 Citations (Scopus)

Abnormal vocal cord movement in patients with and without airway obstruction and asthma symptoms

Low, K., Ruane, L., Uddin, N., Finlay, P., Lau, K. K., Hamza, K., Holmes, P. W., Hamilton, G. & Bardin, P. G., 1 Feb 2017, In : Clinical & Experimental Allergy. 47, 2, p. 200-207 8 p.

Research output: Contribution to journalArticleOtherpeer-review

17 Citations (Scopus)

Abnormal vocal cord movement treated with botulinum toxin in patients with asthma resistant to optimised management

Baxter, M., Uddin, A. K. M. N., Raghav, S., Leong, P., Low, K., Hamza, K., Holmes, P., Hamilton, G. S., Thyagarajan, D., Lau, K. K-P. & Bardin, P. G., 2014, In : Respirology. 19, 4, p. 531 - 537 7 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion

Wong, C. H. Y., Bozinovski, S., Hertzog, P. J., Hickey, M. J. & Crack, P. J., 2008, In : Journal of Neurochemistry. 107, 1, p. 241 - 252 12 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Absence of the previously reported G protein oncogene (gip2) in ovarian granulosa cell tumors

Shen, Y., Mamers, P., Jobling, T., Burger, H. G. & Fuller, P. J., 1996, In : The Journal of Clinical Endocrinology and Metabolism. 81, 11, p. 4159-4161 3 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

A cancer stem cell origin for human endometrial carcinoma?

Hubbard, S. & Gargett, C. E., 2010, In : Reproduction. 140, 1, p. 23 - 32 10 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Accelerated maturation and abnormal morphology in the preterm neonatal kidney

Sutherland, M., Gubhaju, L., Moore, L., Kent, A., Dahlstrom, J., Horne, R. S. C., Hoy, W., Bertram, J. & Black, M., 2011, In : Journal of the American Society of Nephrology. 22, 7, p. 1365 - 1374 10 p.

Research output: Contribution to journalArticleResearchpeer-review

152 Citations (Scopus)

Acceleration of lung maturation in a human fetus following maternal isotretinoin intake

Fauchere, J-C., Ersch, J., Grant, D. A., Zimmermann, R., Bucher, H. U. & Stallmach, T., 2006, In : Biology of the Neonate. 90, 3, p. 203 - 206 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Acceptability of stem cell therapy by pregnant women

Hodges, R., Bardien, N. & Wallace, E. M., 2012, In : Birth. 39, 2, p. 91 - 97 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Accuracy of a disposable compared to a non-disposable infant T-piece resuscitator

Krabbe, V. B., van Vonderen, J. J., Roehr, C. C. & Te Pas, A. B., 2014, In : European Journal of Pediatrics. 173, 8, p. 1005 - 1009 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A cell type-specific transcriptomic approach to map B cell and monocyte type I interferon-linked pathogenic signatures in Multiple Sclerosis

Severa, M., Rizzo, F., Srinivasan, S., Di Dario, M., Giacomini, E., Buscarinu, M. C., Cruciani, M., Etna, M. P., Sandini, S., Mechelli, R., Farina, A., Trivedi, P., Hertzog, P. J., Salvetti, M., Farina, C. & Coccia, E. M., 1 Jul 2019, In : Journal of Autoimmunity. 101, p. 1-16 16 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A comparative study of renal function in male and female spiny mice - sex specific responses to a high salt challenge

Dickinson, H., Moritz, K. M. & Kett, M. M., 2013, In : Biology of Sex Differences. 4, 1 (Art # 21), p. 1 - 8 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

A comparison of gene transcription in cloned bovine embryos produced by different nuclear transfer techniques. IF2.220

Daniels, R., Hall, V. J., French, A. J., Korfiatis, N. A. & Trounson, A. O., 2001, In : Molecular Reproduction and Development. 60, p. 281 - 288 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A comparison of high-frequency jet ventilation and synchronised intermittent mandatory ventilation in preterm lambs

Musk, G. C., Polglase, G., Bunnell, J. B., Nitsos, I., Tingay, D. G. & Pillow, J., 2015, In : Pediatric Pulmonology. 50, 12, p. 1286 - 1293 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

A comparison of mesenchymal precursor cells and amnion epithelial cells for enhancing cervical interbody fusion in an ovine model

Goldschlager, T., Ghosh, P., Zannettino, A., Williamson, M. M., Rosenfeld, J. V., Itescu, S. & Jenkin, G., 2011, In : Neurosurgery. 68, 4, p. 1025 - 1034 10 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

A comparison of nasal trauma in preterm infants extubated to either heated humidified high-flow nasal cannulae or nasal continuous positive airway pressure

Collins, C. L., Barfield, C. P., Horne, R. S. C. & Davis, P. G., 2014, In : European Journal of Pediatrics. 173, 2, p. 181-186 6 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

A Comparison of Two Ovine Lumbar Intervertebral Disc Injury Models for the Evaluation and Development of Novel Regenerative Therapies

Daly, C. D., Ghosh, P., Badal, T., Shimmon, R., Jenkin, G., Oehme, D., Cooper-White, J., Sher, I., Chandra, R. V. & Goldschlager, T., 1 Dec 2018, In : Global Spine Journal. 8, 8, p. 847-859 13 p.

Research output: Contribution to journalArticleResearchpeer-review

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1 Citation (Scopus)

A conserved IFN-alpha receptor tyrosine motif directs the biological response to type I IFNs

Zhao, W., Lee, C., Piganis, R., Plumlee, C., De Weerd, N. A., Hertzog, P. J. & Schindler, C., 2008, In : Journal of Immunology. 180, 8, p. 5483 - 5489 7 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Acquired convergence of hormone signaling in breast cancer: ER and PR transition from functionally distinct in normal breast to predictors of metastatic disease

Hilton, H. N., Doan, T. B., Graham, J. D., Oakes, S. R., Silvestri, A., Santucci, N., Kantimm, S., Huschtscha, L. I., Ormandy, C. J., Funder, J. W., Simpson, E. R., Kuczek, E. S., Leedman, P. J., Tilley, W. D., Fuller, P. J., Muscat, G. E. O. & Clarke, C. L., 2014, In : Oncotarget. 5, 18, p. 8651 - 8664 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
18 Citations (Scopus)

Acquiring signalling specificity from the cytokine receptor gp130

Ernst, M. & Jenkins, B., 2004, In : Trends in Genetics. 20, 1, p. 23 - 32 10 p.

Research output: Contribution to journalArticleResearchpeer-review

226 Citations (Scopus)

A critical evaluation of ovarian tissue cryopreservation and grafting as a strategy for preserving the human female gamete

Shaw, J. M., Dawson, K. & Trounson, A. O., 1998, In : Reproductive Medicine Review. p. 163 - 183 21 p.

Research output: Contribution to journalShort ReviewOtherpeer-review

A critical look at the inhibin hypothesis in the male

de Kretser, D. M., Risbridger, G. P., Sun, YT. & Robertson, D., 1990, Neuroendocrine Regulation of Gonadotrophs. Yen, SSK. & Vale, WW. (eds.). p. 179-188 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Otherpeer-review

A critical role of Oct4A in mediating metastasis and disease-free survival in a mouse model of ovarian cancer

Samardzija, C., Luwor, R. B., Volchek, M., Quinn, M. A., Findlay, J. J. K. & Ahmed, N., 2015, In : Molecular Cancer. 14, p. 1 - 19 19 p., 152.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

A crucial requirement for Hedgehog signaling in small cell lung cancer

Park, K-S., Martelotto, L., Peifer, M., Sos, M., Karnezis, A., Mahjoub, M., Bernard, K., Conklin, J., Szczepny, A., Yuan, J., Guo, R., Ospina, B., Falzon, J., Bennett, S., Brown, T., Markovic, A., Devereux, W., Ocasio, C., Chen, J., Stearns, T. & 6 others, Thomas, R., Dorsch, M., Buonamici, S., Watkins, D., Peacock, C. & Sage, J., 2011, In : Nature Medicine. 17, 11, p. 1504 - 1508 5 p.

Research output: Contribution to journalArticleResearchpeer-review

160 Citations (Scopus)

Actigraphy and sleep/wake diaries

Biggs, S. N. & Horne, R. S. C., 2013, The Oxford Handbook of Infant, Child and Adolescent Sleep and Behaviour. Wolfson, A. R. & Montgomery-Downs, H. E. (eds.). 1st ed. USA: Oxford University Press, p. 189 - 203 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

Actigraphy correctly predicts sleep behavior in infants who are younger than six months, when compared with polysomnography

So, K., Buckley, P., Adamson, T. M. & Horne, R. S. C., 2005, In : Pediatric Research. 58, 4, p. 761 - 765 5 p.

Research output: Contribution to journalArticleResearchpeer-review

97 Citations (Scopus)

Activating transcription factor 3 contributes to Toll-like receptor-mediated macrophage survival via repression of Bax and Bak

Thompson, M., Xu, D. & Williams, B. R. G., 2013, In : Journal of Interferon and Cytokine Research. 33, 11, p. 682 - 693 12 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Activating transcription factor 3 expression as a marker of response to the histone deacetylase inhibitor pracinostat

Sooraj, D., Xu, D., Cain, J. E., Gold, D. P. & Williams, B. R. G., 1 Jul 2016, In : Molecular Cancer Therapeutics. 15, 7, p. 1726-1739 14 p.

Research output: Contribution to journalArticleResearchpeer-review

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5 Citations (Scopus)

Activation of cGAS-dependent antiviral responses by DNA intercalating agents

Pepin, G., Nejad, C., Thomas, B. J., Ferrand, J., McArthur, K., Bardin, P. G., Williams, B. R. G. & Gantier, M. P., 9 Jan 2017, In : Nucleic Acids Research. 45, 1, p. 198-205 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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10 Citations (Scopus)

Activation of ERBB4 in glioblastoma can contribute to increased tumorigenicity and influence therapeutic response

Donoghue, J. F., Kerr, L. T., Alexander, N. W., Greenall, S. A., Longano, A. B., Gottardo, N. G., Wang, R., Tabar, V., Adams, T. E., Mischel, P. S. & Johns, T. G., 1 Aug 2018, In : Cancers. 10, 8, 16 p., 243.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Activation of in vivo- and in vitro-derived porcine oocytes by using multiple electrical pulses

Grupen, C. G., Verma, P. J., Du, Z. T., MacIlfatrick, S. M., Ashman, R. J. & Nottle, M. B., 2000, In : Reproduction, Fertility and Development. 11, 8, p. 457 - 462 6 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Activation of protease-activated receptor-2 leads to inhibition of osteoclast differentiation

Smith, R. A., Ransjo, M., Tatarczuch, L., Song, S-J., Pagel, C. N., Morrison, J. R., Pike, R. N. & Mackie, E. J., 2004, In : Journal of Bone and Mineral Research. 19, 3, p. 507 - 516 10 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: Implications for glucose metabolism

Cvrljevic, A., Akhavan, D., Wu, M., Martinello, P., Furnari, F., Johnston, A., Guo, D., Pike, L., Cavenee, W., Scott, A., Mischel, P., Hoogenraad, N. & Johns, T., 2011, In : Journal of Cell Science. 124, Pt 17, p. 2938 - 2950 13 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Activation of the kynurenine pathway and increased production of the excitotoxin quinolinic acid following traumatic brain injury in humans

Yan, E. B., Frugier, T. J., Lim, C. K., Heng, B., Sundaram, G., Tan, M., Rosenfeld, J. V., Walker, D. W., Guillemin, G. J. & Morganti-Kossmann, M. C., 12 Dec 2015, In : Journal of Neuroinflammation. 12, 1, 17 p., 110.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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34 Citations (Scopus)