Hudson Institute - Department of Molecular and Translational Science

Therapeutic targeting of the colorectal epigenome

Firestein, R.

1/01/20 → 31/12/24

Project: Research

Treating Inflammation in the Male Reproductive Tract

Hedger, M. & Meinhardt, A.

1/01/20 → 31/12/23

Project: Research

Innate mucosal sensing & shaping of the human-microbiome

Hertzog, P., Wells, C., Hartland, E. & Forster, S.

National Health & Medical Research Council (NHMRC)

1/01/20 → 31/12/24

Project: Research

Finding the balance – Reducing inflammation during severe influenza infections

Tate, M. & Mansell, A.

National Health & Medical Research Council (NHMRC)

1/01/20 → 31/12/22

Project: Research

Programmed Cell Death Signalling in Innate Immunity

Lawlor, K.

1/01/20 → 31/01/23

Project: Research

Role of A1 in repressing mitochondrial apoptosis to limit pathogen clearance

Lawlor, K.

1/01/20 → 31/12/22

Project: Research

SRMRSTDC: Selective regulation of mineralocorticoid receptor (MR) signalling for the treatment of diabetic cardiac myopathies

Young, M.

1/01/20 → 31/12/20

Project: Research

Interventional Immunology in Early Life Diseases

Nold, C.

1/01/20 → 31/12/24

Project: Research

Microbiome derived candidates to revolutionise treatment of inflammatory bowel disease

Forster, S. & Giles, E.

1/01/20 → 31/12/23

Project: Research

Precision Oncology: Directing New Therapeutic Interventions for Ovarian Cancer Patients

Stephens, A., Bilandzic, M., Firestein, R., Hertzog, P., Chu, S., DeFazio, A., Bowtell, D. D. L., Jobling, T., Goss, G. & Kryzs, N.

1/01/20 → 31/12/20

Project: Research

Towards precision microbiology: new strategies to combat bacterial infection

Hartland, E.

National Health & Medical Research Council (NHMRC)

1/01/20 → 31/12/24

Project: Research

Advancing Women’s Urogynecological Health using Micro/Nanotechnologies

Mukherjee, S., Werkmeister, J. A., Wood, B. & Rosamilia, A.

1/01/20 → 31/12/23

Project: Research

Genetic regulation of avian sex determination

Smith, C., Harley, V. & Serralbo, O.

1/01/20 → 31/12/22

Project: Research

Developmental Events Affecting Male Fertility and Reproductive Pathologies

Loveland, K., Rajpert-De Meyts, E., Schuppe, H. C., Meinhardt, A., Almstrup, K., Jorgensen, A. & Guo, J.

National Health & Medical Research Council (NHMRC)

1/01/20 → 31/12/23

Project: Research

PACIFIC-Real World: First real-world data on unresectable stage III NSCLC patients treated with durvalumab after chemoradiotherapy (D4194R00005)

Markman, B. & Baker, E.

17/10/19 → 31/12/24

Project: Research

Novel bacteria as therapeutic candidates in Inflammatory Bowel Disease

Giles, E., Forster, S. & Abud, H.

1/10/19 → 30/09/20

Project: Research

Children’s Brain Cancer Clinical Trial Program

Gottardo, N., Strong, R. & Jones, J.

Foundation for Children (FFC)

1/10/19 → 30/09/24

Project: Research

Pilot Study of Nivolumab in Pediatric Patients with Hypermutant Cancers

Ziegler, D. & Strong, R.

Cure Brain Cancer Foundation

1/10/19 → 30/09/22

Project: Research

A Phase 1a/1b Multicentre, Open label, Dose escalation and Dose expansion Study to Evaluate the Safety, Pharmacokinetics, And Antitumor Activity of Ak104 in Subjects with Advanced Solid Tumours

Markman, B.

20/09/19 → 19/09/24

Project: Research

Predicting response to lenalidomide based induction: Real World Experience

Grigoriadis, G.

Celgene Pty Ltd

12/09/19 → 28/02/23

Project: Research

Hudson-Monash Paediatric Precision Medicine Program: Phase 2

Firestein, R., Cain, J., Gough, D., Huang, A., Daly, R., Williams, B. & Rosenbluh, S.

1/09/19 → 30/08/22

Project: Research

Investigating the roles of non-coding RNAs in inflammatory signalling and cancer

Conos, S. & Lawlor, K.

5/08/19 → 28/02/22

Project: Research

Endometriosis susceptibility genes in endometrial stem/progenitor cells

Gargett, C., Montgomery, G. & Rombauts, L.

United States Department of Defense (DoD)

1/08/19 → 31/07/22

Project: Research

TTOCLC: Therapeutic Targeting of the Leader Cell population in Ovarian Cancer

Bilandzic, M. & Stephens, A.

1/07/19 → 30/06/22

Project: Research

Children's Brain Cancer Research - CB4BC Grant

Gottardo, N. & Strong, R.

Carrie Bickmore's Beanies 4 Brain Cancer Foundation

1/07/19 → 30/06/24

Project: Research

Precision Medicine for hypertension: Early detection of primary aldosteronism

Yang, J., Fuller, P., Young, M., Stowasser, M., Russell, G., Bach, L., Gilfillan, C., Lu, Z. X., Reid, C., Chen, G. & Gwini, S.

1/07/19 → 30/06/21

Project: Research

Bacterial communities in metropolitan, rural and indigenous Australians

Forster, S. & Gibney, K. B.

12/06/19 → 11/06/23

Project: Research

A Phase la/lb, Open-Label, Multiple-Dose, Dose-Escalation and Expansion Study of the Anti-PD-1 Monoclonal Antibody CS1003 in Subjects with Advanced Solid Tumors

Markman, B.

6/06/19 → 5/06/24

Project: Research

An Open-Label, Randomized, Phase 3 Trial of Nivolumab, or Nivolumab plus Ipilimumab, versus platinum doublet chemotherapy in Subjects with Chemotherapy-Naive Stage IV or Recurrent Non-Small Cell Lung Cancer (NSCLC) study

Markman, B.

3/06/19 → 2/06/24

Project: Research

Bazedoxifene – A New Selective Estrogen Receptor Modulator Treatment for People with Schizophrenia

Kulkarni, J., Gurvich, C., Thomas, N., Sundram, S., Hill, R. & Chu, S.

1/06/19 → 31/05/22

Project: Research

A Phase 1b Study of Talimogene Laherparepvec in Combination With Atezolizumab in Subjects with Triple Negative Breast Cancer and Colorectal Cancer with Liver Metastases

Markman, B.

20/05/19 → 19/05/24

Project: Research

A Phase 1a/1b Study of FPA150, an Anti-B7-H4 Antibody, in Patients with Advanced Solid Tumors

Markman, B.

30/04/19 → 29/04/24

Project: Research

The PARC study: A phase I/II study evaluating the safety and activity of Pegylated recombinant human Arginase (BCT-100) Relapsed/refractory Cancers of Children and Young Adults

Kirby, M. L., McCowage, G., Ziegler, D., Mussai, F., Strong, R. & Jones, J.

Australian Government Department of Health

2/04/19 → 31/12/22

Project: Research

Phase I evaluation of LY2606368 for children and adolescents with refractory or recurrent medulloblastoma brain tumours

Gottardo, N., Robinson, G. W., Gajjar, A., Pfister, S. M., Witt, O., Endersby, R., Stewart, C. F., Jones, J. & Strong, R.

Carrie Bickmore's Beanies 4 Brain Cancer Foundation, Australian Government Department of Health

1/04/19 → 31/03/24

Project: Research

SIOPEN : SIOPEN neuroblastoma clinical trials in Australia and New Zealand

Strong, R., Trahair, T. & Jones, J.

Children's Cancer Foundation

1/04/19 → 31/03/24

Project: Research

COZMOS: Phase I/Ib trial of combined 5'azacitidine and carboplatin for recurrent/refractory pediatric brain and solid tumors

Hansford, J. R., Kellie, S., Valvi, S., Ramaswamy, V., Jones, J. & Strong, R.

Carrie Bickmore's Beanies 4 Brain Cancer Foundation, Australian Government Department of Health

1/04/19 → 31/03/22

Project: Research

A Phase 1b, Open-Label, Multiple Dose, Dose Escalation and Expansion Study to Investigate the Safety , Pharmacokinetics and Antitumor Activity of the Anti-PD-1 Monoclonal Antibody BGB-A317 in Combination with the PARP Inhibitor BGB-290 in Subjects with Advanced Solid Tumors

Markman, B.

25/03/19 → 24/03/24

Project: Research

Modulation Of the Tumour Microenvironment Using Either Vascular Disrupting Agents or STAT3 Inhibition in Order to Synergise with PD1 Inhibition in Microsatellite Stable, Refractory Colorectal Cancer

Markman, B.

8/03/19 → 7/03/24

Project: Research

A Phase 1, Open-Label, Multicenter, Dose-Escalation Study to Evaluate the Safety and Tolerability of SHR-1316 in Subjects with Advanced Solid Tumors

Markman, B.

28/02/19 → 27/02/24

Project: Research

Primary Aldosteronism: Prevalence, Clinical Features, and Biomarkers

Libianto, R. & Fuller, P.

Heart Foundation

18/02/19 → 17/02/22

Project: Research

Primary Aldosteronism: Prevalence, Clinical Features, and Biomarkers

Libianto, R. & Fuller, P.

18/02/19 → 17/02/22

Project: Research

Using next generation sequencing technology to improve the diagnosis of pancreatic cancer

Croagh, D., Southey, M., Jenkins, B., Segelov, E., Rathi, V., Holt, B. A., Pilgrim, C., Bhutani, M. & Tagkalidis, P.

Victorian Cancer Agency

15/02/19 → 14/02/23

Project: Research

A Phase 1/1b Multicenter Study to Evaluate the Humanized Anti-CD 73 Antibody, CP-I006, As A Single Agent, In Combination With CPI-444, And In Combination With Pembrolizumab In Adult Subjects With Advanced Cancers

Markman, B.

12/02/19 → 11/02/24

Project: Other

Project 220: My Room Clinical Research Fellowship

Cain, J., Firestein, R. & Downie, P.

1/02/19 → 31/01/22

Project: Research

A Phase 1/2a Study of BMS-986205 Administered in Combination with Nivolumab (BMS-936558, anti-PD-1 Monoclonal Antibody) in Advanced Cancers

Markman, B.

29/01/19 → 28/01/24

Project: Research

A Phase II Clinical Trial Evaluating Ipilimumab & Nivolumab in Combination for the Treatment of Rare Gastrointestinal, Neuro-Endocrine and Gynaecological Cancers

Markman, B.

11/01/19 → 10/01/24

Project: Research

Targeting key regulators of innate immunity in inflammation-associated cancer

Jenkins, B.

1/01/19 → 31/12/23

Project: Research

Role of programmed cell death in NLRP3 inflammasome activation and Metabolic Syndrome

Lawlor, K.

1/01/19 → 31/12/21

Project: Research

Molecular Genetics of Human Sexual Differentiation

Harley, V.

1/01/19 → 31/12/23

Project: Research

Increasing Accessibility of Regenerative Medicine Through Innovative Solutions

Lim, R.

1/01/19 → 31/12/22

Project: Research