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2015

Assessment and implications of scattered microbeam and broadbeam synchrotron radiation for bystander effect studies

Lobachevsky, P. N., Ivashkevich, A., Forrester, H. B., Stevenson, A. W., Hall, C. J., Sprung, C. N. & Martin, O., 2015, In : Radiation Research. 184, 6, p. 650 - 659 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Blocking HIV-1 transmission in the female reproductive tract: from microbicide development to exploring local antiviral responses

Eid, S. G., Mangan, N., Hertzog, P. J. & Mak, J., 2015, In : Clinical and Translational Immunology. 4, 10, 9 p., e43.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis

Miller, A., Brooks, G. D. C., McLeod, L., Ruwanpura, S. M. & Jenkins, B. J., 19 Mar 2015, In : Oncogene. 34, 12, p. 1510 - 1519 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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8 Citations (Scopus)

Dynamic control of type I interferon signalling by an integrated network of negative regulators

Porritt, R. A. & Hertzog, P. J., 2015, In : Trends in Immunology. 36, 3, p. 150 - 160 11 p.

Research output: Contribution to journalArticleResearchpeer-review

77 Citations (Scopus)

Endogenous murine BST-2/tetherin is not a major restriction factor of influenza A virus infection

Londrigan, S. L., Tate, M., Job, E. R., Moffat, J. M., Wakim, L., Gonelli, C. A., Purcell, D. F. J., Brooks, A. G., Villadangos, J. A., Reading, P. C. & Mintern, J., 2015, In : PLoS ONE. 10, 11, 14 p., e0142925.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

HIV blocks interferon induction in human dendritic cells and macrophages by dysregulation of TBK1

Harman, A. N., Nasr, N., Feetham, A., Galoyan, A., Alshehri, A. A., Rambukwelle, D., Botting, R. A., Hiener, B. M., Diefenbach, E., Diefenbach, R. J., Kim, M., Mansell, A. S. & Cunningham, A. L., 2015, In : Journal of Virology. 89, 13, p. 6575 - 6584 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
45 Citations (Scopus)

Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis

Jones, G. W., McLeod, L., Kennedy, C. L., Bozinovski, S., Najdovska, M. & Jenkins, B. J., 2015, In : Atherosclerosis. 238, 2, p. 321 - 328 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Immunological markers that predict radiation toxicity

Sprung, C. N., Forrester, H. B., Siva, S. & Martin, O., 2015, In : Cancer Letters. 368, 2, p. 191 - 197 7 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Increased outer membrane vesicle formation in a Helicobacter pylori tolB mutant

Turner, L. J., Praszkier, J., Hutton, M. L., Steer, D. L., Ramm, G., Liaskos, M. & Ferrero, R. L., 2015, In : Helicobacter. 20, 4, p. 269 - 283 15 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Inflammatory and non-inflammatory roles for toll-like receptors in gastrointestinal cancer

West, A. C. & Jenkins, B. J., 2015, In : Current Pharmaceutical Design. 21, 21, p. 2968 - 2977 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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8 Citations (Scopus)

Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis

Jones, G. W., Bombardieri, M., Greenhill, C. J., McLeod, L., Nerviani, A., Rocher-Ros, V., Cardus, A., Williams, A. S., Pitzalis, C., Jenkins, B. J. & Jones, S. A., 2015, In : The Journal of Experimental Medicine. 212, 11, p. 1793 - 1802 10 p.

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)

Loss of host type-I IFN signaling accelerates metastasis and impairs NK-cell antitumor function in multiple models of breast cancer

Rautela, J., Baschuk, N., Slaney, C. Y., Jayatilleke, K. M., Xiao, K., Bidwell, B. N., Lucas, E. C., Hawkins, E., Lock, P., Wong, C. S. F., Chen, W., Anderson, R. L., Hertzog, P. J., Andrews, D. M., Moller, A. & Parker, B. S., 2015, In : Cancer Immunology Research. 3, 11, p. 1207 - 1217 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
24 Citations (Scopus)

Oxidative DNA damage caused by inflammation may link to stress-induced non-targeted effects

Sprung, C. N., Ivashkevich, A., Forrester, H. B., Redon, C. E., Georgakilas, A. G. & Martin, O., 2015, In : Cancer Letters. 356, 1, p. 72 - 81 10 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Recombinant production of functional full-length and truncated human TRAM/TICAM-2 adaptor protein involved in Toll-like receptor and interferon signaling

Ullah, M. O., Valkov, E., Ve, T., Williams, S., Mas, C., Mansell, A. S. & Kobe, B., 2015, In : Protein Expression and Purification. 106, p. 31 - 40 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors

Sarvestani, S., Stunden, H. J., Behlke, M. A., Forster, S., McCoy, C., Tate, M., Ferrand, J. F. P., Lennox, K. A., Latz, E., Williams, B. R. G. & Gantier, M. P. M., 30 Jan 2015, In : Nucleic Acids Research. 43, 2, p. 1177-1188 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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23 Citations (Scopus)

Spatiotemporal requirements for IRF7 in mediating type I IFN-dependent susceptibility to blood-stage Plasmodium infection

Edwards, C. L., Best, S. E., Gun, S. Y., Claser, C., James, K. R., Montes de Oca, M., Sebina, I., de Labastida Rivera, F. R., Amante, F. H., Hertzog, P. J., Engwerda, C. R., Renia, L. & Haque, A. K. M. N., 2015, In : European Journal of Immunology. 45, 1, p. 130 - 141 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Synthesis and structural characterisation of bismuth(III) hydroxamates and their activity against Helicobacter pylori

Pathak, A., Blair, V. L., Ferrero, R. L., Junk, P. C., Tabor, R. F. & Andrews, P. C., 2015, In : Dalton Transactions. 44, 38, p. 16903-16913 11 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

The intracellular location, mechanisms and outcomes of NOD1 signaling

Liaskos, M., 2015, In : Cytokine. 74, 2, p. 207 - 212 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
2014
23 Citations (Scopus)

Bismuth(iii) beta-thioxoketonates as antibiotics against Helicobacter pylori and as anti-leishmanial agents

Andrews, P. C., Blair, V. L., Ferrero, R. L., Junk, P. C., Kedzierski, L. & Peiris, J. M. R., 2014, In : Dalton Transactions. 43, 3, p. 1279 - 1291 13 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Bismuth(III) complexes derived from alpha-amino acids: the impact of hydrolysis and oxido-cluster formation on their activity against Helicobacter pylori

Busse, M., Border, E. C., Junk, P. C., Ferrero, R. L. & Andrews, P. C., 2014, In : Dalton Transactions. 43, 48, p. 17980 - 17990 11 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis

Kennedy, C. L., Najdovska, M., Tye, Y. M. H., McLeod, L., Yu, L., Jarnicki, A. G., Bhathal, P. S., Putoczki, T. L., Ernst, M. R. & Jenkins, B. J., 2014, In : Oncogene. 33, 19, p. 2540 - 2546 7 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Effective pulmonary delivery of an aerosolized plasmid DNA vaccine via surface acoustic wave nebulization

Rajapaksa, A. E., Ho, J., Qi, A., Bischof, R., Nguyen, T-H., Tate, M., Piedrafita, D. M., McIntosh, M. P., Yeo, L. Y-M., Meeusen, E. N. T., Coppel, R. L. & Friend, J. R., 2014, In : Respiratory Research. 15, p. 1 - 12 12 p., 60.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
38 Citations (Scopus)

Glucocorticosteroids enhance replication of respiratory viruses: effect of adjuvant interferon

Thomas, B., Porritt, R. A., Hertzog, P. J., Bardin, P. G. & Tate, M., 2014, In : Scientific Reports. 4, Art. ID: 7176, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
27 Citations (Scopus)

Identification of a pathogenic variant in TREX1 in early-onset cerebral systemic lupus erythematosus by Whole-exome sequencing

Ellyard, J. I., Jerjen, R., Martin, J. L., Lee, A. Y. S., Field, M. A., Jiang, S. H., Capello, J., Naumann, S. K., Andrews, T. D., Scott, H. S., Casarotto, M. G., Goodnow, C., Chaitow, J., Pascual, V., Hertzog, P. J., Alexander, S. I., Cook, M. C. & Vinuesa, C. G., 2014, In : Arthritis and Rheumatology. 66, 12, p. 3382 - 3386 5 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Identification of a radiation sensitivity gene expression profile in primary fibroblasts derived from patients who developed radiotherapy-induced fibrosis

Forrester, H. B., Li, J., Leong, T., McKay, M. J. & Sprung, C. N., 2014, In : Radiotherapy and Oncology. 111, 2, p. 186 - 193 8 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

IL-1beta and IL-18: inflammatory markers or mediators of hypertension?

Murali Krishnan, S., Sobey, C. G., Latz, E., Mansell, A. S. & Drummond, G. R., 2014, In : British Journal of Pharmacology. 171, 24, p. 5589 - 5602 14 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice

Ruwanpura, S. M., McLeod, L., Brooks, G. D. C., Bozinovski, S., Vlahos, R., Longano, A., Bardin, P. G., Anderson, G. & Jenkins, B. J., 2014, In : Respirology. 19, 3, p. 419 - 427 9 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Inflammation and gastrointestinal cancer: an overview

Marusawa, H. & Jenkins, B. J., 2014, In : Cancer Letters. 345, 2, p. 153 - 156 4 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8

Sarvestani, S., Tate, M., Moffat, J. M., Jacobi, A. M., Behlke, M. A., Miller, A., Beckham, S. A., McCoy, C., Chen, W., Mintern, J., O'Keeffe, M., John, M., Williams, B. R. G. & Gantier, M. P. M., 2014, In : Journal of Virology. 88, 2, p. 799 - 810 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
14 Citations (Scopus)

Interleukin-6 signaling drives fibrosis in unresolved inflammation

Fielding, C. A., Jones, G. W., McLoughlin, R. M., McLeod, L., Hammond, V. J., Uceda, J., Williams, A. S., Lambie, M., Foster, T. L., Liao, C-T., Rice, C. M., Greenhill, C. J., Colmont, C. S., Hams, E., Coles, B., Kift-Morgan, A., Newton, Z., Craig, K. J., Williams, J. D., Williams, G. T. & 7 others, Davies, S. J., Humphreys, I. R., O'Donnell, V. B., Taylor, P. R., Jenkins, B. J., Topley, N. & Jones, S. A., 2014, In : Immunity. 40, 1, p. 40 - 50 11 p.

Research output: Contribution to journalArticleResearchpeer-review

140 Citations (Scopus)

Intragenic controls utilizing radiation-induced alternative transcript regions improves gene expression biodosimetry

Forrester, H. B. & Sprung, C. N., 2014, In : Radiation Research. 181, 3, p. 314 - 323 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

In vivo comparison of local versus systemic delivery of immunostimulating siRNA in HPV-driven tumours

Khairuddin, N., Blake, S., Firdaus, F., Steptoe, R. J., Behlke, M. A., Hertzog, P. J. & McMillan, N. A. J., 2014, In : Immunology and Cell Biology. 92, 2, p. 156 - 163 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

IRF7 in the Australian black flying fox, Pteropus alecto: evidence for a unique expression pattern and functional conservation

Zhou, P. C., Cowled, C., Mansell, A. S., Monaghan, P., Green, D., Wu, L., Shi, Z., Wang, L. & Baker, M. L., 2014, In : PLoS ONE. 9, 8 (Art. ID: e103875), p. 1 - 13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
22 Citations (Scopus)

Mechanism of bacterial interference with TLR4 signaling by Brucella Toll/interleukin-1 receptor domain-containing protein TcpB

Alaidarous, M., Ve, T., Casey, L. W., Valkov, E., Ericsson, D. J., Ullah, M. O., Schembri, M. A., Mansell, A. S., Sweet, M. J. & Kobe, B., 2014, In : Journal of Biological Chemistry. 289, 2, p. 654 - 668 15 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Mobilization of viable tumor cells into the circulation during radiation therapy

Martin, O., Anderson, R. L., Russell, P. A., Cox, R. A., Ivashkevich, A., Swierczak, A., Doherty, J., Jacobs, D. H. M., Smith, J., Siva, S., Daly, P. E., Ball, D. L., Martin, R. F. & MacManus, M. P., 2014, In : International Journal of Radiation Oncology Biology Physics. 88, 2, p. 395 - 403 9 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

Playing hide and seek: how glycosylation of the influenza virus hemagglutinin can modulate the immune response to infection

Tate, M., Job, E. R., Deng, Y. M., Gunalan, V., Maurer-Stroh, S. & Reading, P. C., 2014, In : Viruses. 6, 3, p. 1294 - 1316 23 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
127 Citations (Scopus)

Porphyromonas gingivalis lipopolysaccharide weakly activates M1 and M2 polarized mouse macrophages but induces inflammatory cytokines

Holden, J. A., Attard, T. J., Laughton, K. M., Mansell, A. S., O'Brien-Simpson, N. M. & Reynolds, E. C., 2014, In : Infection and Immunity. 82, 10, p. 4190 - 4203 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
39 Citations (Scopus)

Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation

Dowling, J. K., Becker, C., Bourke, N., Corr, S. C., Connolly, D. J., Quinn, S. R., Pandolfi, P. P., Mansell, A. S. & O'Neill, L. A. J., 2014, In : Journal of Biological Chemistry. 289, 10, p. 6429 - 6437 9 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Purification and biological characterization of soluble, recombinant mouse IFNbeta expressed in insect cells

Stifter, S. A., Gould, J. A., Mangan, N., Reid, H. H., Rossjohn, J., Hertzog, P. J. & De Weerd, N. A., 2014, In : Protein Expression and Purification. 94, p. 7 - 14 8 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Rab8a interacts directly with PI3Kgamma to modulate TLR4-driven PI3K and mTOR signalling

Luo, L., Wall, A. A., Yeo, J. C., Condon, N. D., Norwood, S. J., Schoenwaelder, S. M., Chen, K. W., Jackson, S., Jenkins, B. J., Hartland, E. L., Schroder, K., Collins, B. M., Sweet, M. J. & Stow, J. L., 2014, In : Nature Communications. 5, (Art. No.:4407), p. 1 - 13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
61 Citations (Scopus)

Role of caspase-1 in nuclear translocation of IL-37, release of the cytokine, and IL-37 inhibition of innate immune responses

Bulau, A-M., Nold, M. F., Li, S., Nold, C. A., Fink, M., Mansell, A. S., Schwerd, T., Hong, J-W., Rubartelli, A., Dinarello, C. A. & Bufler, P., 2014, In : Proceedings of the National Academy of Sciences. 111, 7, p. 2650 - 2655 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
113 Citations (Scopus)

Soluble IFN receptor potentiates in vivo type I IFN signaling and exacerbates TLR4-mediated septic shock

Samarajiwa, S. A., Mangan, N., Hardy, M. P. A., Najdovska, M., Dubach, D., Braniff, S-J., Owczarek, C. M. & Hertzog, P. J., 2014, In : Journal of Immunology. 192, 9, p. 4425 - 4435 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

STAT1 plays a role in TLR signal transduction and inflammatory responses

Luu, K., Greenhill, C. J., Majoros, A., Decker, T., Jenkins, B. J. & Mansell, A. S., 2014, In : Immunology and Cell Biology. 92, 9, p. 761 - 769 9 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

The early monocytic response to cytomegalovirus infection is MyD88 dependent but occurs independently of common inflammatory cytokine signals

Wikstrom, M. E., Khong, A., Fleming, P., Kuns, R. D., Hertzog, P. J., Frazer, I. H., Andoniou, C. E., Hill, G. R. & Degli-Esposti, M. A., 2014, In : European Journal of Immunology. 44, 2, p. 409 - 419 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling

Irving, A. T., Mimuro, H., Kufer, T. A., Lo, C. Y-W., Wheeler, R., Turner, L. J., Thomas, B., Malosse, C., Gantier, M. P. M., Casillas, L. N., Votta, B. J., Bertin, J., Boneca, I. G., Sasakawa, C., Philpott, D., Ferrero, R. L. & Liaskos, M., 2014, In : Cell Host and Microbe. 15, 5, p. 623 - 635 13 p.

Research output: Contribution to journalArticleResearchpeer-review

97 Citations (Scopus)

The macrophage galactose-type lectin can function as an attachment and entry receptor for influenza virus

Ng, W. C., Liong, S., Tate, M., Irimura, T., Denda-Nagai, K., Brooks, A. G., Londrigan, S. L. & Reading, P. C., 2014, In : Journal of Virology. 88, 3, p. 1659 - 1672 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
26 Citations (Scopus)

The TLR signaling adaptor TRAM interacts with TRAF6 to mediate activation of the inflammatory response by TLR4

Verstak, B., Stack, J., Ve, T., Mangan, M., Hjerrild, K., Jeon, J., Stahl, R., Latz, E., Gay, N., Kobe, B., Bowie, A. G. & Mansell, A. S., 2014, In : Journal of leukocyte biology. 96, 3, p. 427 - 436 10 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)
7 Citations (Scopus)

Type I IFN signaling in CD8- DCs impairs Th1-dependent malaria immunity

Haque, A. K. M. N., Best, S. E., Montes de Oca, M., James, K. R., Ammerdorffer, A., Edwards, C. L., de Labastida Rivera, F. R., Amante, F. H., Bunn, P. T., Sheel, M., Sebina, I., Koyama, M., Varelias, A., Hertzog, P. J., Kalinke, U., Gun, S. Y., Renia, L., Ruedl, C., MacDonald, K. P. A., Hill, G. R. & 1 others, Engwerda, C. R., 2014, In : Journal of Clinical Investigation. 124, 6, p. 2483 - 2496 14 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)