Faculty of Pharmacy and Pharmaceutical Sciences

Research Output 1969 2020

Erratum: Correction: Comparison of bulk and microfluidic methods to monitor the phase behaviour of nanoparticles during digestion of lipid-based drug formulations using in situ X-ray scattering (Soft matter (2019) 15 46 (9565-9578))

Hong, L., Sesen, M., Hawley, A., Neild, A., Spicer, P. T. & Boyd, B. J., 7 Jan 2020, In : Soft Matter. 16, 1, p. 276-276 1 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access

Evaluation of Operational Models of Agonism and Allosterism at Receptors with Multiple Orthosteric Binding Sites

Gregory, K., Giraldo, J., Diao, J., Christopoulos, A. & Leach, K., 2020, In : Molecular Pharmacology. 97, 1, p. 35-45 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Safety and effectiveness of direct oral anticoagulants vs warfarin in people with atrial fibrillation and dementia

Fanning, L., Lau, W. C. Y., Mongkhon, P., Man, K. K. C., Bell, J. S., Ilomäki, J., Dārziņš, P., Lau, K. K., Wei, L. & Wong, I. C. K., Jan 2020, (Accepted/In press) In : Journal of the American Medical Directors Association. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2019

(S)-(−)-Fluorenylethylchloroformate (FLEC); preparation using asymmetric transfer hydrogenation and application to the analysis and resolution of amines

Al Amin, M., Camerino, M. A., Mountford, S. J., Ma, X., Manallack, D. T., Chalmers, D. K., Wills, M. & Thompson, P. E., 1 Jan 2019, In : Tetrahedron. 75, 43, p. 1-7 7 p., 130591.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity

Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 others, Price, R. N., Marfurt, J., Charman, S. A., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Edstein, M. D., Avery, V. M. & Baell, J. B., 1 Jan 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2485-2498 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6-Phenylpyrimidin-4-ones as Positive Allosteric Modulators at the M1 mAChR: The Determinants of Allosteric Activity

Jorg, M. T., van der Westhuizen, E. T., Khajehali, E., Burger, W. A. C., White, J., Choy, K. H. C., Tobin, A. B., Sexton, P. M., Valant, C., Capuano, B., Christopoulos, A. & Scammells, P. J., 20 Mar 2019, In : ACS Chemical Neuroscience. 10, 3, p. 1099-1114 16 p.

Research output: Contribution to journalArticleResearchpeer-review

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Kaminskas, L. M., Williams, C. C., Leong, N. J., Chan, L. J., Butcher, N. J., Feeney, O. M., Porter, C. J. H., Tyssen, D., Tachedjian, G. & Ascher, D. B., 1 Apr 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 218-226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Acquisition of analgesic properties by the cholecystokinin (CCK)/CCK2 receptor system within the amygdala in a persistent inflammatory pain condition

Roca-Lapirot, O., Fossat, P., Ma, S., Egron, K., Trigilio, G., López-González, M. J., Covita, J., Bouali-Benazzouz, R., Favereaux, A., Gundlach, A. L. & Landry, M., 1 Feb 2019, In : Pain. 160, 2, p. 345-357 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Activated platelets in the tumor microenvironment for targeting of antibody-drug conjugates to tumors and metastases

Yap, M. L., McFadyen, J. D., Wang, X., Ziegler, M., Chen, Y. C., Willcox, A., Nowell, C. J., Scott, A. M., Sloan, E. K., Hogarth, P. M., Pietersz, G. A. & Peter, K., 1 Jan 2019, In : Theranostics. 9, 4, p. 1154-1169 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Activation of pruritogenic TGR5, MRGPRA3, and MRGPRC11 on colon-innervating afferents induces visceral hypersensitivity

Castro, J., Harrington, A. M., Lieu, T., Garcia-Caraballo, S., Maddern, J., Schober, G., O’Donnell, T., Grundy, L., Lumsden, A. L., Miller, P., Ghetti, A., Steinhoff, M. S., Poole, D. P., Dong, X., Chang, L., Bunnett, N. & Brierley, S. M., 19 Sep 2019, In : JCI Insight. 4, 18, 42 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Acute β-adrenoceptor mediated glucose clearance in brown adipose tissue; a distinct pathway independent of functional insulin signaling

Olsen, J. M., Åslund, A., Bokhari, M. H., Hutchinson, D. S. & Bengtsson, T., Dec 2019, In : Molecular Metabolism. 30, p. 240-249 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Adherence, Persistence, and Switching Among People Prescribed Sodium Glucose Co-transporter 2 Inhibitors: A Nationwide Retrospective Cohort Study

Ofori-Asenso, R., Liew, D., Lalic, S., Mazidi, M., Magliano, D. J., Ademi, Z., Bell, J. S. & Ilomaki, J., 3 Sep 2019, (Accepted/In press) In : Advances in Therapy. 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Adipocyte-specific deletion of IL-6 does not attenuate obesity-induced weight gain or glucose intolerance in mice

Whitham, M., Pal, M., Petzold, T., Hjorth, M., Egan, C. L., Brunner, J. S., Estevez, E., Iliades, P., Zivanovic, B., Reibe, S., Hughes, W. E., Findeisen, M., Hidalgo, J. & Febbraio, M. A., 30 Sep 2019, In : American journal of physiology. Endocrinology and metabolism. 317, 4, p. E597-E604 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Adrenoceptor regulation of the mechanistic target of rapamycin in muscle and adipose tissue

Chia, L. Y., Evans, B., Mukaida, S., Bengtsson, T., Hutchinson, D. & Sato, M., 1 Jul 2019, In : British Journal of Pharmacology. 176, 14, p. 2433-2448 16 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Adrenoceptors in white, brown, and brite adipocytes

Evans, B. A., Merlin, J., Bengtsson, T. & Hutchinson, D. S., 1 Jul 2019, In : British Journal of Pharmacology. 176, 14, p. 2416-2432 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Adrenoceptors—New roles for old players

Michel, M. C., Bond, R. A. & Summers, R. J., 1 Jul 2019, In : British Journal of Pharmacology. 176, 14, p. 2339-2342 4 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
2 Citations (Scopus)

Advances in Microfluidic Blood–Brain Barrier (BBB) Models

Oddo, A., Peng, B., Tong, Z., Wei, Y., Tong, W. Y., Thissen, H. & Voelcker, N. H., 23 May 2019, (Accepted/In press) In : Trends in Biotechnology. 20 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Tieu, T., Alba Martin, M., Elnathan, R., Cifuentes-Rius, A. & Voelcker, N. H., Jan 2019, In : Advanced Therapeutics. 2, 1, 25 p., 1800095.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

A fluorogenic probe based on chelation-hydrolysis-enhancement mechanism for visualizing Zn2+ in Parkinson's disease models

Zhang, G., Zhao, Y., Peng, B., Li, Z., Xu, C., Liu, Y., Zhang, C., Voelcker, N. H., Li, L. & Huang, W., 14 Apr 2019, In : Journal of Materials Chemistry B. 7, 14, p. 2252-2260 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Agonist-dependent development of delta opioid receptor tolerance in the colon

DiCello, J. J., Saito, A., Rajasekhar, P., Sebastian, B. W., McQuade, R. M., Gondin, A. B., Veldhuis, N. A., Canals, M., Carbone, S. E. & Poole, D. P., Aug 2019, In : Cellular and Molecular Life Sciences. 76, 15, p. 3033–3050 18 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

Patil, R., Mohanty, B., Liu, B., Chandrashekaran, I. R., Headey, S. J., Williams, M. L., Clements, C. S., Ilyichova, O., Doak, B. C., Genissel, P., Weaver, R., Vuillard, L., Halls, M. L., Porter, C. J. H. & Scanlon, M. J., 8 Mar 2019, In : Journal of Biological Chemistry. 294, 10, p. 3720-3734 15 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore

Sun, Y., Kakinen, A., Zhang, C., Yang, Y., Faridi, A., Davis, T. P., Cao, W., Ke, P. C. & Ding, F., 28 Jun 2019, In : Nanoscale. 11, 24, p. 11933-11945 13 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., May 2019, In : Small. 15, 18, 10 p., 1805166.

Research output: Contribution to journalArticleResearchpeer-review

Analysing student problem solving: Successes and challenges

Yuriev, E., 2019, p. 10-10. 1 p.

Research output: Contribution to conferenceAbstractOther

Open Access
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4 Citations (Scopus)
2 Citations (Scopus)

An apically located hybrid guanylate cyclase-ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii

Yang, L., Uboldi, A. D., Seizova, S., Wilde, M. L., Coffey, M. J., Katris, N. J., Yamaryo-Botté, Y., Kocan, M., Bathgate, R. A. D., Stewart, R. J., McConville, M. J., Thompson, P. E., Botté, C. Y. & Tonkin, C. J., 31 May 2019, In : Journal of Biological Chemistry. 294, 22, p. 8959-8972 14 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Anesthetic technique and cancer outcomes: a meta-analysis of total intravenous versus volatile anesthesia

Yap, A., Lopez-Olivo, M. A., Dubowitz, J., Hiller, J., Riedel, B. & the Global Onco-Anesthesia Research Collaboration Group, 15 May 2019, In : Canadian Journal of Anesthesia. 66, 5, p. 546-561 16 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL

Suys, E. J. A., Warren, D. B., Pham, A. C., Nowell, C. J., Clulow, A. J., Benameur, H., Porter, C. J. H., Pouton, C. W. & Chalmers, D. K., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 193-204 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform

Grace, J. L., Amado, M., Reid, J. C., Elliott, A. G., Landersdorfer, C. B., Truong, N. P., Kempe, K., Cooper, M. A., Davis, T. P., Montembault, V., Pascual, S., Fontaine, L., Velkov, T., Quinn, J. F. & Whittaker, M. R., 21 Nov 2019, In : Journal of Materials Chemistry B. 7, 43, p. 6796-6809 14 p.

Research output: Contribution to journalArticleResearchpeer-review

A Novel Class of N-Sulfonyl and N-Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells

Yong, C., Devine, S. M., Gao, X., Yan, A., Callaghan, R., Capuano, B. & Scammells, P. J., 1 Jan 2019, (Accepted/In press) In : ChemMedChem.

Research output: Contribution to journalArticleResearchpeer-review

A novel online platform promotes asynchronous class preparation and thought transparency

Shin, J., Gruenberg, K. & Brock, T., 1 Jan 2019, (Accepted/In press) In : Currents in Pharmacy Teaching and Learning. 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M. S., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 others, Failes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 Jan 2019, In : Oncogene. 38, 20, p. 3824-3842 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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16 Citations (Scopus)

An Overview of 3D Printing Technologies for Soft Materials and Potential Opportunities for Lipid-based Drug Delivery Systems

Vithani, K., Goyanes, A., Jannin, V., Basit, A. W., Gaisford, S. & Boyd, B. J., 1 Jan 2019, In : Pharmaceutical Research. 36, 1, 20 p., 4.

Research output: Contribution to journalReview ArticleResearchpeer-review

Antimicrobial activity and structure of a consensus human β-defensin and its comparison to a novel putative hBD10

Rodriguez, A., Pedersen, M., Villegas, E., Rivas-Santiago, B., Villegas-Moreno, J., Amero, C., Norton, R. S. & Corzo, G., 1 Jan 2019, (Accepted/In press) In : Proteins: Structure, Function and Bioinformatics.

Research output: Contribution to journalArticleResearchpeer-review

A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain

Ramirez Garcia, P. D., Retamal, J. S., Shenoy, P., Imlach, W., Sykes, M., Truong, N., Constandil, L., Pelissier, T., Nowell, C. J., Khor, S. Y., Layani, L. M., Lumb, C., Poole, D. P., Lieu, T., Stewart, G. D., Mai, Q. N., Jensen, D. D., Latorre, R., Scheff, N. N., Schmidt, B. L. & 5 others, Quinn, J. F., Whittaker, M. R., Veldhuis, N. A., Davis, T. P. & Bunnett, N. W., Dec 2019, In : Nature Nanotechnology. 14, p. 1150-1159 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

Anderson, B., Poole, D. P., Aurelio, L., Ng, G. Z., Fleischmann, M., Kasperkiewicz, P., Morissette, C., Drag, M., van Driel, I. R., Schmidt, B. L., Vanner, S. J., Bunnett, N. & Edgington-Mitchell, L., 1 Dec 2019, In : Scientific Reports. 9, 1, 12 p., 13295.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion

Salim, M., Fraser-Miller, S. J., Sutton, J. J., Berzinš, K., Hawley, A., Clulow, A. J., Beilles, S., Gordon, K. C. & Boyd, B. J., 2 May 2019, In : Journal of Physical Chemistry Letters. 10, 9, p. 2258-2263 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

A Proof of Concept for 3D Printing of Solid Lipid-Based Formulations of Poorly Water-Soluble Drugs to Control Formulation Dispersion Kinetics

Vithani, K., Goyanes, A., Jannin, V., Basit, A. W., Gaisford, S. & Boyd, B. J., 1 Jul 2019, In : Pharmaceutical Research. 36, 7, 13 p., 102.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A review of coronial investigations into medication-related deaths in Australian residential aged care

Jokanovic, N., Ferrah, N., Lovell, J. J., Weller, C., Bugeja, L., Bell, J. S. & Ibrahim, J. E., Apr 2019, In : Research in Social and Administrative Pharmacy. 15, 4, p. 410-416 7 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

A sequential native chemical ligation-thiol-Michael addition strategy for polymer-polymer ligation

Rajakanthan, A., Jongh, P. A. J. M. D., Town, J. S., Wilson, P. & Kempe, K., 14 Oct 2019, In : Polymer Chemistry. 10, 38, p. 5242-5250 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A systematic review and meta-analysis of treatment outcomes following antibiotic therapy among patients with carbapenem-resistant Klebsiella pneumoniae infections

Agyeman, A. A., Bergen, P. J., Rao, G. G., Nation, R. L. & Landersdorfer, C. B., 12 Nov 2019, (Accepted/In press) In : International Journal of Antimicrobial Agents. 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

AT1R-AT2R-RXFP1 functional crosstalk in myofibroblasts: Impact on the therapeutic targeting of renal and cardiac fibrosis

Chow, B. S. M., Kocan, M., Shen, M., Wang, Y., Han, L., Chew, J. Y., Wang, C., Bosnyak, S., Mirabito-Colafella, K. M., Barsha, G., Wigg, B., Johnstone, E. K. M., Hossain, M. A., Pfleger, K. D. G., Denton, K. M., Widdop, R. E., Summers, R. J., Bathgate, R. A. D., Hewitson, T. D. & Samuel, C. S., 1 Jan 2019, In : Journal of the American Society of Nephrology. 30, 11, p. 2191-2207 17 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A Thieno[2,3-d]pyrimidine Scaffold is a Novel Negative Allosteric Modulator of the Dopamine D2 Receptor

Fyfe, T. J., Zarzycka, B., Lim, H. D., Kellam, B., Mistry, S. N., Katrich, V., Scammells, P. J., Lane, J. R. & Capuano, B., 1 Oct 2019, In : Journal of Medicinal Chemistry. 62, 1, p. 174-206 33 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β 2 -adrenoceptors without causing classical receptor desensitization

Mukaida, S., Sato, M., Öberg, A. I., Dehvari, N., Olsen, J. M., Kocan, M., Halls, M. L., Merlin, J., Sandström, A. L., Csikasz, R. I., Evans, B. A., Summers, R. J., Hutchinson, D. S. & Bengtsson, T., 1 May 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 316, 5, p. R666-R677 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

C/EBPβ regulates the M2 transcriptome in β-adrenergic-stimulated macrophages

Lamkin, D. M., Srivastava, S., Bradshaw, K. P., Betz, J. E., Muy, K. B., Wiese, A. M., Yee, S. K., Waggoner, R. M., Arevalo, J. M. G., Yoon, A. J., Faull, K. F., Sloan, E. K. & Cole, S. W., 2019, In : Brain, Behavior, and Immunity. 80, p. 839-848 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Can microbes increase exercise performance in athletes?

Turpin-Nolan, S. M., Joyner, M. J. & Febbraio, M. A., 1 Nov 2019, In : Nature Reviews Endocrinology. 15, 11, p. 629-630 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

1 Citation (Scopus)

Carboxylated Cy5-Labeled Comb Polymers Passively Diffuse the Cell Membrane and Target Mitochondria

Mahmoud, A. M., De Jongh, P. A. J. M., Briere, S., Chen, M., Nowell, C. J., Johnston, A. P. R., Davis, T. P., Haddleton, D. M. & Kempe, K., 28 Aug 2019, In : ACS Applied Materials and Interfaces. 11, 34, p. 31302-31310 9 p.

Research output: Contribution to journalArticleResearchpeer-review