Faculty of Medicine, Nursing and Health Sciences

RECIPE: Randomised controlled trial (RCT) of ROTEM-guided blood component administration versus standard of care in patients with cirrhosis and coagulopathy undergoing invasive procedures.

Majeed, A., Janko, N. E., Roberts, S., Kemp, W., Nandurkar, H., Gow, P. J. & Thompson, K.

5/12/19 → 31/08/21

Project: Research

Targeting Life-threatening ‘superbug’ Pseudomonas aeruginosa: A Systems and Computational Approach

Han, M.

2/12/19 → 20/12/19

Project: Research

EPITAPH: Establishing the prevalence of healthcare associated infections in two Australian private hospitals

Russo, P., Mitchell, B. G., Cheng, A. & Stewardson, A.

Cardinal Health 503 Pty Ltd

1/12/19 → 30/11/20

Project: Research

Establishing the role of apoptosis and mtDNA in lupus pathobiology

Kile, B.

1/12/19 → 30/11/21

Project: Research

Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging, Efficacy and Safety Study with Inhaled RVT-1601 for the Treatment of Persistent Cough in Patients with Idiopathic Pulmonary Fibrosis (IPF): SCENIC Trial

Glaspole, I. & Symons, K. M.

22/11/19 → 30/11/21

Project: Research

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Multiple Center Study to Evaluate the Safety, Tolerability, and Efficacy of Seladelpar Administered for 24 Weeks in Adult Patients with Primary Sclerosing Cholangitis (PSC)

Roberts, S.

22/11/19 → 31/12/21

Project: Research

A 52-Week, open-label, single-arm study to evaluate the safety and tolerability of 24-hour daily exposure of continuous subcutaneous infusion of ABBV-951 in subjects with Parkinson's disease

Bertram, K. & Burn, K.

22/11/19 → 30/11/21

Project: Research

A Multicenter, Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Bimekizumab in the Treatment of Subjects with Active Psoriatic Arthritis

Roberts, L.

21/11/19 → 20/11/24

Project: Research

Unmet need for targeted therapies in Australian and AsiaPacific SLE patients

Morand, E. & Kandane-Rathnayake, R.

GlaxoSmithKline Australia Pty Ltd

20/11/19 → 30/11/20

Project: Research

A randomized, multicenter, parallel-group, Phase III study to compare the efficacy of arfolitixorin versus leucovorin in combination with 5-fluorouracil, oxaliplatin, and bevacizumab in patients with advanced colorectal cancer

Frentzas, S.

20/11/19 → 19/11/24

Project: Research

Classification and analysis of resectability outcomes in non-metastatic pancreatic cancer - European vs Australian experience.

Zalcberg, J., Croagh, D. & Samra, J.

19/11/19 → 4/12/20

Project: Research

True Protein: Pre-, Pro-, Syn-biotic and Active Living Systematic Literature Review and Clinical Study

Da Costa, R.

18/11/19 → 17/11/20

Project: Research

A Phase 1a/1b, Multicenter, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Pharmacokinetics, and Antitumor Activity of AK112 in Subjects with Advanced Solid Tumors

Parakh, S.

15/11/19 → 14/11/24

Project: Research

AIPI Evidence Synthesis Methodologies

Turner, T., Green, S. & Murano, M.

Palladium International LLC

15/11/19 → 30/06/20

Project: Research

A Randomized, Multicenter, Double-blind, Placebo-controlled Phase 3 Study of Nivolumab Versus Placebo in Combination With Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy in Patients With High-risk, Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor 2-Negative (HER2-) Primary Breast Cancer

Webber, K.

15/11/19 → 14/11/24

Project: Research

RSV MAT-004 - A Phase II observer-blind study to assess safety, reactogenicity and immunogenicity of GSK Biologicals’ investigational RSV Maternal unadjuvanted vaccine (GSK3888550A), in healthy pregnant women and infants born to vaccinated mothers

Buttery, J.

15/11/19 → 14/11/24

Project: Research

AUSCAPPS - To support GPs, pharmacists and nurses working in primary care to delive long acting reversible contraceptive (LARC) methods and medical termination of pregnancy (MTOP) services

Mazza, D.

Bayer Australia Ltd

13/11/19 → 31/12/19

Project: Research

Non-pharmacological distraction therapy for pain and anxiety in pre-hospital paediatric patients. A pilot study

Delorenzo, A., Eastwood, K., Stock, A. & Smith, K.

Australian and New Zealand College of Paramedicine

13/11/19 → 31/08/20

Project: Research

Developing molecular targets to improve human implantation

Rombauts, L.

12/11/19 → 11/11/20

Project: Research

A Phase 3 Double-blinded, Two-arm Study to Evaluate the Safety and Efficacy of Pembrolizumab (MK-3475) versus Placebo as Adjuvant Therapy in Participants with Hepatocellular Carcinoma and Complete Radiological Response after Surgical Resection or Local Ablation

Roberts, S. & Lewis, P.

8/11/19 → 30/06/23

Project: Research

The Clinical Outcomes Measurement in Perioperative Medicine, Anaesthesia & Surgery Study (COMPASS): A prospective multi-centre observational study of perioperative risk factors and outcomes in Australia

Reilly, J., Myles, P., Brown, W., Gabbe, B. & Hodgson, C.

8/11/19 → 7/11/20

Project: Research

A Phase 3, Multicentre, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn's Disease

Moore, G.

7/11/19 → 6/11/24

Project: Research

A Phase 3, Multicentre, Open Label Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

Moore, G.

7/11/19 → 6/11/24

Project: Research

A Phase 3, Multicentre, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn's Disease

Moore, G.

7/11/19 → 6/11/24

Project: Research

A Phase 1/Phase 2 Clinical Study to Evaluate the Safety and Efficacy of a Combination of MK-4280 and Pembrolizumab (MK-3475) in Participants with Hematologic Malignancies

Gregory, G.

6/11/19 → 5/11/24

Project: Research

Australian Communities Foundation, Hopetoun Fund

Currie, P.

6/11/19 → 6/11/20

Project: Research

A Phase I, open-label, multicenter, study of WVT078 in subjects with relapsed and/or refractory multiple myeloma

Spencer, A. & Kennedy, N.

6/11/19 → 31/12/24

Project: Research

Double NAC trial: Investigation of increased N-acetylcysteine dosing in patients treated for paracetamol overdose.

Wong, A.

Australasian College for Emergency Medicine

6/11/19 → 5/11/21

Project: Research

A Phase 3, Randomized, Double-blind Trial of Pembrolizumab (MK-3475) Plus Enzalutamide Versus Placebo Plus Enzalutamide in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (KEYNOTE-641)

Pook, D.

6/11/19 → 5/11/24

Project: Research

Modelling enhanced TB control through active case finding in the Marshall Islands

Trauer, J., Ragonnet, R., Mcbryde, E. S. & Williams, B.

5/11/19 → 31/12/19

Project: Research

Fostering and suPAWting engagement in meaningful activity and social connection: Dogs as a conduit to community inclusion for people with cognitive disabilities

Bould, E., Callaway, E., Lalor, A. & Warren, N.

Monash University – Internal School Contribution, Melba Support Services

4/11/19 → 28/02/21

Project: Research

Statistical analysis and report on effectiveness of continuous glucose monitoring device among patients with type 1 diabetes

Earnest, A.

Juvenile Diabetes Research Foundation Australia (JDRF Australia)

1/11/19 → 30/12/19

Project: Research

Assessing recycling and waste in Interventional Radiology

Clements, W., Victor, T., Houlihan, C., Corish, C. & Chow, J.

1/11/19 → 12/12/20

Project: Research

A Phase 1b/2 Study of KZR-616 in Patients with Systemic Lupus Erythematosus with and without Nephritis

Hoi, A.

1/11/19 → 31/10/24

Project: Research

A Phase 3 Study of Pembrolizumab in Combination with Carboplatin/Taxane (Paclitaxel or Nab-paclitaxel) Followed by Pembrolizumab with or without Maintenance Olaparib in the First-line Treatment of Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)

Briggs, P.

1/11/19 → 31/10/24

Project: Research

An International, Phase 3, Open-label, Randomized Study of BGB-3111 Compared with Bendamustine plus Rituximab in Patients with Previously Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Opat, S.

1/11/19 → 31/10/24

Project: Research

A Phase 3 Multicenter, Open-Label, Randomized, Controlled Study of Oral Infigratinib versus Gemcitabine with Cisplatin in Subjects with Advanced/Metastatic or Inoperable Cholangiocarcinoma with FGFR2 Gene Fusions/Translocations: the PROOF Trial

Harris, M.

1/11/19 → 31/10/24

Project: Research

Centre for Research Excellence - Women’s Health in Reproductive life

Teede, H., Norman, R. J., Mishra, G. D., Boyle, J., Hart, R. J., Mol, B., Moran, L., Hickey, M., Laven, J. S. E. & Rodgers, R. J.

1/11/19 → 31/10/24

Project: Research

How does Toxoplasma Gondii, a common worldwide infection, affect brain injury?

Sun, M., Shultz, S., Tonkin, C. & Sobey, C.

1/11/19 → 1/11/20

Project: Research

Centre of Research Excellence in Health in Preconception and Pregnancy: Prevention of maternal obesity

Skouteris, H., Teede, H., Boyle, J., Moran, L., Thangaratinam, S., Hills, A. P., Venn, A., Jack, B., Norman, R. J. & Ademi Delaney, Z.

National Health & Medical Research Council (NHMRC)

1/11/19 → 31/10/24

Project: Research

 An evaluation of an electronic perinatal mental health screening program

Clarke, J. R., Gibson-Helm, M., Skouteris, H., Boyle, J. & Huynh, K.

Monash Health

1/11/19 → 1/11/22

Project: Research

PP2A and tau – novel treatment targets in ischemic stroke and poststroke epilepsy

Casillas-Espinosa, P. & Shultz, S.

1/11/19 → 31/10/21

Project: Research

A Study to Evaluate the Feasibility and Safety of the Millipede Transcatheter Annuloplasty Ring System in Patients with Functional Mitral Regurgitation (Millipede Feasibility Study)

Gooley, R.

1/11/19 → 31/10/24

Project: Research

Evaluation of TAOK2 as a novel therapeutic target for personalized treatment of triple negative and HER2 breast cancers

Daly, R.

National Breast Cancer Foundation

1/11/19 → 30/10/21

Project: Research

Better health through better trials: A national network to develop and implement innovative clinical trials methodology

Wolfe, R., Lee, K. J., Forbes, A., Webb, S., Marschner, I. C., Makrides, M., Snelling, T., Davidson, A., Heritier, S. & Yelland, L.

National Health & Medical Research Council (NHMRC)

1/11/19 → 31/10/24

Project: Research

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Safety, Tolerability, and Efficacy of GS-9674 in Non-Cirrhotic Subjects with Primary Sclerosing Cholangitis

Roberts, S. & Lewis, P.

30/10/19 → 31/12/21

Project: Research

Testing the efficacy of spirulina produced antiobodies to Clostridium difficile in two Clostridium difficile disease mouse models (treatment and prophylaxis)

Lyras, D.

Lumen Biosciences

29/10/19 → 5/06/20

Project: Research

A Phase 3, Randomized, Open Label Study to Compare Nivolumab plus Concurrent Chemoradiotherapy (CCRT) followed by Nivolumab plus Ipilimumab or Nivolumab plus CCRT Followed by Nivolumab vs CCRT followed by Durvalumab in Previously Untreated, Locally Advanced Non-small Cell Lung Cancer (LA NSCLC)

Moore, M., Singhal, N., Chin, V. T., Karikios, D. & Hawkins, C.

29/10/19 → 31/12/23

Project: Research

A Phase 3, Open-label Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination therapy in Subjects with Cystic Fibrosis Who Are Heterozygous for the F508del Mutation and a Gating or Residual Function Mutation (F/G and F/RF Genotypes)

Wilson, J.

28/10/19 → 31/12/24

Project: Research

A Phase 2 Study of Olaparib in combination with pembrolizumab in participants with homologous recombination repair mutation (HRRm) and/or homologous recombination deficiency (HRD)-positive advanced cancer

Frentzas, S.

28/10/19 → 27/10/24

Project: Research