Research Output

Review Article

Relaxin 3, a novel member of the insulin/relaxin superfamily of peptide hormones.

Bathgate, R. A. D., Scott, D. J., Samuel, C. S., Burazin, T. CD., Layfield, S., Claasz, A. A., Dawson, N. F., Ma, S., Bond, C., Summers, R. J., Wade, J. D. & Tregear, G. W., 2002, In : Biology of Reproduction.

Research output: Contribution to journalReview ArticleResearchpeer-review

Relieving ER stress to target NASH-driven hepatocellular carcinoma

Reibe, S. & Febbraio, M. A., 1 Feb 2019, In : Nature Reviews Endocrinology. 15, 2, p. 73-74 2 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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2 Citations (Scopus)

Renal α adrenoceptors

Summers, R. J., 1 Dec 1984, In : Federation Proceedings. 43, 14, p. 2917-2922 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

69 Citations (Scopus)

Rules of Engagement: GPCRs and G Proteins

Glukhova, A., Draper-Joyce, C. J., Sunahara, R. K., Christopoulos, A., Wootten, D. L. & Sexton, P. M., 7 Sep 2018, In : ACS Pharmacology & Translational Science. 1, 2, p. 73-83 11 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Sarcolemmal dependence of cardiac protection and stress-resistance: roles in aged or diseased hearts

See Hoe, L. E., May, L. T., Headrick, J. P. & Peart, J. N., Oct 2016, In : British Journal of Pharmacology. 173, 20, p. 2966-2991 26 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Signalling in response to sub-picomolar concentrations of active compounds: Pushing the boundaries of GPCR sensitivity

Civciristov, S. & Halls, M. L., Jul 2019, In : British Journal of Pharmacology. 176, 14, p. 2382-2401 20 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)

Strength in numbers - An arrestin interaction code

Draper-Joyce, C. J. & Christopoulos, A., 1 Jun 2018, In : Nature Structural & Molecular Biology. 25, 6, p. 437-439 3 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Structural basis for allosteric modulation of class b g protein-coupled receptors

Wootten, D. & Miller, L. J., 6 Jan 2020, In : Annual Review of Pharmacology and Toxicology. 60, p. 89-107 19 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

6 Citations (Scopus)

Structural insights into G-protein-coupled receptor allostery

Thal, D. M., Glukhova, A., Sexton, P. M. & Christopoulos, A., 5 Jul 2018, In : Nature. 559, 7712, p. 45-53 9 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

84 Citations (Scopus)

Targeting adenosine receptors for the treatment of cardiac fibrosis

Vecchio, E. A., White, P. J. & May, L. T., 5 May 2017, In : Frontiers in Pharmacology. 8, MAY, 7 p., 243.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
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19 Citations (Scopus)

Targeting adenosine receptor signaling in cancer immunotherapy

Sek, K., Mølck, C., Stewart, G. D., Kats, L., Darcy, P. K. & Beavis, P. A., 1 Dec 2018, In : International Journal of Molecular Sciences. 19, 12, 23 p., 3837.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
File
39 Citations (Scopus)

The actions of relaxin on the human cardiovascular system

Sarwar, M., Du, X. J., Dschietzig, T. B. & Summers, R. J., 1 May 2017, In : British Journal of Pharmacology. 174, 10, p. 933-949 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

29 Citations (Scopus)

The adenosine A 2B G protein-coupled receptor: Recent advances and therapeutic implications

Vecchio, E. A., White, P. J. & May, L. T., 1 Jan 2019, In : Pharmacology and Therapeutics. 198, p. 20-33 14 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

9 Citations (Scopus)

The class B G-protein-coupled GLP-1 receptor: an important target for the treatment of type-2 diabetes mellitus

Miller, L. J., Sexton, P. M., Dong, M. & Harikumar, K. G., 2014, In : International Journal of Obesity. 4, p. S9-S13 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The Concise Guide to PHARMACOLOGY 2015/16: Overview

CGTP Collaborators, 1 Dec 2015, In : British Journal of Pharmacology. 172, 24, p. 5729-5743 15 p.

Research output: Contribution to journalReview ArticleOtherpeer-review

Open Access
File
153 Citations (Scopus)

The nature of efficacy at G protein-coupled receptors

Zhao, P. & Furness, S. G. B., 1 Dec 2019, In : Biochemical Pharmacology. 170, 113647.

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)

Therapeutic Potential of Lipoxin A4 in Chronic Inflammation: Focus on Cardiometabolic Disease

Fu, T., Mohan, M., Brennan, E. P., Woodman, O. L., Godson, C., Kantharidis, P., Ritchie, R. H. & Qin, C., 17 Jan 2020, In : ACS Pharmacology & Translational Science. 3, 1, p. 43-55 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

The role of ceramides in metabolic disorders: when size and localization matters

Turpin-Nolan, S. M. & Brüning, J. C., 1 Apr 2020, In : Nature Reviews Endocrinology. 16, 4, p. 224-233 10 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

3 Citations (Scopus)

The role of placental homeobox genes in human fetal growth restriction

Murthi, P., Rajaraman, G., Brennecke, S. P. & Kalionis, B., 2011, In : Journal of Pregnancy. 2011, 11 p., 548171.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
8 Citations (Scopus)

β-adrenoceptor subtypes and their desensitization mechanisms

Summers, R. J., Kompa, A. & Roberts, S. J., 1 Jan 1997, In : Journal of Autonomic Pharmacology. 17, 6, p. 331-343 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

46 Citations (Scopus)
Short Survey

Coding GPCR-G protein specificity

Furness, S. G. B. & Sexton, P. M., 1 Oct 2017, In : Cell Research. 27, 10, p. 1193-1194 2 p.

Research output: Contribution to journalShort SurveyResearchpeer-review

Open Access
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1 Citation (Scopus)

Molecular insights into metabotropic glutamate receptor allosteric modulations

Gregory, K. J. & Conn, P. J., 1 Jul 2015, In : Molecular Pharmacology. 88, 1, p. 188-202 15 p.

Research output: Contribution to journalShort SurveyResearchpeer-review

31 Citations (Scopus)

To Bind or Not to Bind: Unravelling GPCR Polypharmacology

Sexton, P. M. & Christopoulos, A., 8 Feb 2018, In : Cell. 172, 4, p. 636-638 3 p.

Research output: Contribution to journalShort SurveyOtherpeer-review

Open Access
File
7 Citations (Scopus)