Research Output

Visualizing Ligand Binding to a GPCR In Vivo Using NanoBRET

Alcobia, D. C., Ziegler, A. I., Kondrashov, A., Comeo, E., Mistry, S., Kellam, B., Chang, A., Woolard, J., Hill, S. J. & Sloan, E. K., 31 Aug 2018, In : iScience. 6, p. 280-288 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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7 Citations (Scopus)

What determines the magnitude of cellular response for activation of G protein-coupled receptors?

Furness, S. G. B., Wootten, D. & Sexton, P. M., 6 Feb 2017, In : Cell Cycle. 16, 5, p. 392-394 3 p.

Research output: Contribution to journalEditorialOtherpeer-review

Working memory deficits in transgenic rats overexpressing human adenosine A2A receptors in the brain

Gimenez-Llort, L., Schiffmann, S., Shmidt, T., Canela, L., Camon, L., Wassholm, M., Canals, M., Terasmaa, A., Fernandez-Teruel, A., Tobena, A., Popova, E., Ferre, S., Agnati, L., Ciruela, F., Martinez, E., Kruger, J., Lluis, C., Franco, R., Fuxe, K. & Bader, M., 2007, In : Neurobiology of Learning and Memory. 87, 1, p. 42 - 56 15 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

Xenobiotics and loss of cell adhesion drive distinct transcriptional outcomes by aryl hydrocarbon receptor signaling

Hao, N., Lee, K. L., Furness, S. G. B., Bosdotter, C., Poellinger, L. & Whitelaw, M. L., 2012, In : Molecular Pharmacology. 82, 6, p. 1082 - 1093 12 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Zinc-finger nuclease enhanced gene targeting in human embryonic stem cells

Hartley, B. J., Fabb, S. A., Finnin, B. A. L., Haynes, J. M. & Pouton, C. W., 2014, In : Journal of Visualized Experiments. 2014, 90, 7 p., e51764.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes

Sato, M., Evans, B. A., Sandström, A. L., Chia, L. Y., Mukaida, S., Thai, B. S., Nguyen, A., Lim, L., Tan, C. Y. R., Baltos, J. A., White, P. J., May, L. T., Hutchinson, D. S., Summers, R. J. & Bengtsson, T., 1 Feb 2018, In : Biochemical Pharmacology. 148, p. 27-40 14 p.

Research output: Contribution to journalArticleResearchpeer-review

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6 Citations (Scopus)

α1- and α2-adrenoceptors of the circular myometrium from the dioestrous guinea-pig

Haynes, J. & Pennefather, J. N., 1988, In : Clinical and Experimental Pharmacology and Physiology. 15, 9, p. 695-701 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

α2-adrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression

Lamkin, D. M., Sung, H. Y., Yang, G. S., David, J. M., Ma, J. C. Y., Cole, S. W. & Sloan, E. K., 2015, In : Psychoneuroendocrinology. 51, p. 262-270 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

α2-adrenoceptors in dog kidney: Autoradiographic localization and putative functions

Summers, R. J., Stephenson, J. A., Lipe, S. & Neylon, C. B., 1 Jan 1985, In : Clinical Science. 68, SUPPL. 10

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

β1-adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β3-adrenergic receptor knockout mice via nonshivering thermogenesis

Mattsson, C. L., Csikasz, R. I., Chernogubova, E., Yamamoto, D. L., Hogberg, H. T., Amri, E-Z., Hutchinson, D. S. & Bengtsson, T., Dec 2011, In : American Journal of Physiology - Endocrinology and Metabolism. 301, 6, 11 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

β1-adrenoceptors compensate for β3-adrenoceptors in ileum from β3-adrenoceptor knock-out mice

Hutchinson, D. S., Evans, B. A. & Summers, R. J., 1 Jan 2001, In : British Journal of Pharmacology. 132, 2, p. 433-442 10 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

β1- and β3-adrenoceptor mediated smooth muscle relaxation in hypothyroid rat ileum

Brown, K. J. & Summers, R. J., 16 Mar 2001, In : European Journal of Pharmacology. 415, 2-3, p. 257-263 7 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

β2-Adrenergic receptor expression is associated with biomarkers of tumor immunity and predicts poor prognosis in estrogen receptor-negative breast cancer

Kurozumi, S., Kaira, K., Matsumoto, H., Hirakata, T., Yokobori, T., Inoue, K., Horiguchi, J., Katayama, A., Koshi, H., Shimizu, A., Oyama, T., Sloan, E. K., Kurosumi, M., Fujii, T. & Shirabe, K., 1 Jan 2019, In : Breast Cancer Research and Treatment. 177, 3, p. 603–610 8 p.

Research output: Contribution to journalArticleResearchpeer-review

β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion

Creed, S. J., Le, C. P., Hassan, M., Pon, C. K., Albold, S., Chan, K. T., Berginski, M. E., Huang, Z., Bear, J. E., Lane, J. R., Halls, M. L., Ferrari, D., Nowell, C. J. & Sloan, E. K., 2015, In : Breast Cancer Research. 17, 1, 12 p., 145.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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35 Citations (Scopus)

β2-adrenoceptors on tumor cells play a critical role in stress-enhanced metastasis in a mouse model of breast cancer

Chang, A., Le, C. P., Walker, A. K., Creed, S. J., Pon, C. K., Albold, S., Carroll, D., Halls, M. L., Lane, J. R., Riedel, B., Ferrari, D. & Sloan, E. K., 1 Oct 2016, In : Brain, Behavior, and Immunity. 57, p. 106-115 10 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

β3-adrenoceptor regulation and relaxation responses in mouse ileum

Hutchinson, D. S., Evans, B. A. & Summers, R. J., 1 Jan 2000, In : British Journal of Pharmacology. 129, 6, p. 1251-1259 9 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

β3-Andrenoceptors: Differential regulation and novel subtypes

Summers, R. J., Hutchinson, D. S. & Evans, B. A., 1 Jan 1998, In : Pharmacy and Toxicology, Supplement. 83, 1, p. 37-39 3 p.

Research output: Contribution to journalArticleResearchpeer-review

β-Adrenergic signaling impairs antitumor CD8+ T-cell responses to B-cell lymphoma immunotherapy

Nissen, M. D., Sloan, E. K. & Mattarollo, S. R., 1 Jan 2018, In : Cancer Immunology Research. 6, 1, p. 98-109 12 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

β-adrenergic-stimulated macrophages: comprehensive localization in the M1-M2 spectrum

Lamkin, D. M., Ho, H-Y., Ong, T. H., Kawanishi, C. K., Stoffers, V. L., Ahlawat, N., Ma, J. C. Y., Arevalo, J. M. G., Cole, S. W. & Sloan, E. K., 1 Oct 2016, In : Brain, Behavior, and Immunity. 57, p. 338-346 9 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

β-adrenoceptor subtypes and their desensitization mechanisms

Summers, R. J., Kompa, A. & Roberts, S. J., 1 Jan 1997, In : Journal of Autonomic Pharmacology. 17, 6, p. 331-343 13 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

46 Citations (Scopus)
6 Citations (Scopus)

β-arrestin-biased agonists of the GLP-1 receptor from β-amino acid residue incorporation into GLP-1 analogues

Hager, M. V., Johnson, L. M., Wootten, D., Sexton, P. M. & Gellman, S. H., 16 Nov 2016, In : Journal of the American Chemical Society. 138, 45, p. 14970-14979 10 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

“Selective” class C G protein-coupled receptor modulators are neutral or biased mGlu5 allosteric ligands

Hellyer, S. D., Albold, S., Wang, T., Chen, A. N. Y., May, L. T., Leach, K. & Gregory, K. J., 1 May 2018, In : Molecular Pharmacology. 93, 5, p. 504-514 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)