Research Output

1993

Relaxin: more than just a hormone of pregnancy

Kakouris, H., Eddie, L. W. & Summers, R. J., 1 Jan 1993, In : Trends in Pharmacological Sciences. 14, 1, p. 4-6 3 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Techniques for Assessing the Effects of Pharmaceutical Excipients on the Aggregation of Porcine Growth Hormone

Charman, S. A., Mason, K. L. & Charman, W. N., 1993, In : Pharmaceutical Research. 10, 7, p. 954-962 9 p.

Research output: Contribution to journalArticleResearchpeer-review

106 Citations (Scopus)

The mouse relaxin gene: Nucleotide sequence and expression

Evans, B. A., John, M., Fowler, K. J., Summers, R. J., Cronk, M., Shine, J. & Tregear, G. W., 1 Jan 1993, In : Journal of Molecular Endocrinology. 10, 1, p. 15-23 9 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)
1992

Absence of mitochondrial β-adrenoceptors in guinea pig myocardium: Evidence for tissue disparity

Russell, F. D., Molenaar, P. & Summers, R. J., 1 Jan 1992, In : General Pharmacology. 23, 5, p. 827-832 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Cardiac effects of relaxin in rats

Kakouris, H., Eddie, L. W. & Summers, R. J., 2 May 1992, In : The Lancet. 339, 8801, p. 1076-1078 3 p.

Research output: Contribution to journalArticleResearchpeer-review

96 Citations (Scopus)

Cimaterol reduces beta-adrenergic receptor density in rat skeletal muscles.

Kim, Y. S., Sainz, R. D., Summers, R. J. & Molenaar, P., 1 Jan 1992, In : Journal of Animal Science. 70, 1, p. 115-122 8 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Localization of (-)-[125I]cyanopindolol binding in guinea-pig heart: characteristics of non-β-adrenoceptor related binding in cardiac pacemaker and conducting regions

Molenaar, P., Kompa, A. R., Roberts, S. J., Pak, H. S. & Summers, R. J., 17 Feb 1992, In : Neuroscience Letters. 136, 1, p. 118-122 5 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Regulation of guinea-pig cardiac β-adrenoceptor subtypes after (-)-adrenaline and (-)-noradrenaline treatment

Kompa, A. R., Molenaar, P. & Summers, R. J., 1 Jan 1992, In : Molecular Neuropharmacology. 1, 4, p. 203-210 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Self-Emulsifying Drug Delivery Systems: Formulation and Biopharmaceutic Evaluation of an Investigational Lipophilic Compound

Charman, S. A., Charman, W. N., Rogge, M. C., Wilson, T. D., Dutko, F. J. & Pouton, C. W., 1992, In : Pharmaceutical Research. 9, 1, p. 87-93 7 p.

Research output: Contribution to journalArticleResearchpeer-review

373 Citations (Scopus)
1991

Autoradiographic localization and quantitation of β-adrenoceptor subtypes in the guinea-pig sinoatrial node

Russell, F. D., Molenaar, P., Edyvane, N., Smolich, J. J. & Summers, R. J., 1 Dec 1991, In : Molecular Neuropharmacology. 1, 3, p. 141-147 7 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Characterization of β1- and β2-adrenoceptors in rat skeletal muscles

Kim, Y. S., Sainz, R. D., Molenaar, P. & Summers, R. J., 9 Oct 1991, In : Biochemical Pharmacology. 42, 9, p. 1783-1789 7 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

Localization and characterization of two propranolol resistant (-) [125I]cyanopindolol binding sites in rat skeletal muscle

Molenaar, P., Roberts, S. J., Kim, Y. S., Pak, H. S., Sainz, R. D. & Summers, R. J., 17 Dec 1991, In : European Journal of Pharmacology. 209, 3, p. 257-262 6 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)
1990

Characterization and high resolution autoradiographic localization of β-adrenoceptors in ventricular and conducting regions of guinea-pig heart

Russell, F. D., Molenaar, P., Edyvane, N. & Summers, R. J., 4 Jul 1990, In : European Journal of Pharmacology. 183, 4, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Densitometric analysis of β 1 - and β 2 -adrenoceptors in guinea-pig atrioventricular conducting system

Molenaar, P., Russell, F. D., Shimada, T. & Summers, R. J., 1 Jan 1990, In : Journal of Molecular and Cellular Cardiology. 22, 4, p. 483-495 13 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Differential regulation of beta-1 and beta-2 adrenoceptors in guinea pig atrioventricular conducting system after chronic (-)-isoproterenol infusion

Molenaar, P., Smolich, J. J., Russell, F. D., McMartin, L. R. & Summers, R. J., 1 Jan 1990, In : Journal of Pharmacology and Experimental Therapeutics. 255, 1, p. 393-400 8 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Differential regulation of β1- and β2-adrenoceptors in guinea-pig atrioventricular conducting system after chronic (-)-isoprenaline infusion

Summers, R. J., Smolich, J. J., Russell, F. D., McMartin, L. R. & Molenaar, P., 4 Jul 1990, In : European Journal of Pharmacology. 183, 4, p. 1228-1229 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of prolonged infusion of dopexamine on β1‐ and β2‐adrenoceptors in guinea‐pig myocardium

Williams, D. W., Elnatan, J., Molenaar, P. & Summers, R. J., 1 Jan 1990, In : Journal of Autonomic Pharmacology. 10, 3, p. 127-138 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Excitatory amino acid projections to the periaqueductal gray in the rat: A retrograde transport study utilizing d[3H]aspartate and [3H]GABA

Beart, P. M., Summers, R. J., Stephenson, J. A., Cook, C. J. & Christie, M. J., 1 Jan 1990, In : Neuroscience. 34, 1, p. 163-176 14 p.

Research output: Contribution to journalArticleResearchpeer-review

81 Citations (Scopus)

Localization and function of components of the β-adrenergic system in human and blood vessels

Summers, R. J., 1 Jul 1990, In : European Journal of Pharmacology. 183, 1, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Regulation of β1-, β2-adrenoceptors and adenylate cyclase in guinea-pig heart after chronic (-)-isoprenaline infusion

Williams, D. W., Bull, G. D. J., McMartin, L. R., Molenaar, P. & Summers, R. J., 1 Jan 1990, In : European Journal of Pharmacology. 183, 3, p. 1003-1004 2 p.

Research output: Contribution to journalArticleResearchpeer-review

SIMUL: an accurate method for the determination of receptor subtype proportions using a personal computer

Williams, D. W. & Summers, R. J., 1 Jan 1990, In : Computer Methods and Programs in Biomedicine. 32, 2, p. 137-139 3 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The autoradiographic localization of adenylate cyclase in rat kidney using [3H]forskolin

McMartin, L. R. & Summers, R. J., 15 Mar 1990, In : Biochemical Pharmacology. 39, 6, p. 1019-1028 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
1989

Bidirectional transport of NMDA receptor and ionophore in the vagus nerve

Cincotta, M., Beart, P. M., Summers, R. J. & Lodge, D., 24 Jan 1989, In : European Journal of Pharmacology. 160, 1, p. 167-171 5 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Biochemical characterization of an autoradiographic method for studying excitatory amino acid receptors using l-[3H]glutamate

Cincotta, M., Summers, R. J. & Beart, P. M., 15 Feb 1989, In : Analytical Biochemistry. 177, 1, p. 150-155 6 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Coexistence and localization of β 1 - and β 2 -adrenoceptors in the human heart

Summers, R. J., Molnaar, P., Russell, F., Elnatan, J., Jones, C. R., Buxton, B. F., Chang, V. & Hambley, J., 1 Jan 1989, In : European Heart Journal. 10, SUPPL. B, p. 11-21 11 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

FUNCTION, CHARACTERIZATION AND AUTORADIOGRAPHIC LOCALIZATION AND QUANTITATION OF β‐ADRENOCEPTORS IN CARDIAC TISSUES

Molenaar, P., Russell, F. D., Shimada, T. & Summers, R. J., 1 Jan 1989, In : Clinical and Experimental Pharmacology and Physiology. 16, 6, p. 529-533 5 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

NEW TOOLS FOR THE LOCALIZATION OF SECOND MESSENGER SYSTEMS

Summers, R. J. & McMartin, L. R., 1 Jan 1989, In : Clinical and Experimental Pharmacology and Physiology. 16, 6, p. 549-553 5 p.

Research output: Contribution to journalArticleResearchpeer-review

New views of human cardiac β-adrenoceptors

Jones, C. R., Molenaar, P. & Summers, R. J., 1 Jan 1989, In : Journal of Molecular and Cellular Cardiology. 21, 5, p. 519-535 17 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

57 Citations (Scopus)
1988

An autoradiographic study of muscarinic cholinoceptors in blood vessels: no localization on vascular endothelium

Stephenson, J. A., Gibson, R. E. & Summers, R. J., 24 Aug 1988, In : European Journal of Pharmacology. 153, 2-3, p. 271-283 13 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Autoradiographic localization and densitometric analysis of beta-1 and beta-2 adrenoceptors in the canine left anterior descending coronary artery

Molenaar, P., Jones, C. R., McMartin, L. R. & Summers, R. J., 1 Jan 1988, In : Journal of Pharmacology and Experimental Therapeutics. 246, 1, p. 384-393 10 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Inhibition by cAMP of the phosphoinositide response to α1-adrenoceptor stimulation in rat kidney

Neylon, C. B. & Summers, R. J., 13 Apr 1988, In : European Journal of Pharmacology. 148, 3, p. 441-444 4 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Persistent β-adrenoceptor blockade with alkylating pindolol (BIM) in guinea-pig left atria and trachea

Molenaar, P., Russell, F., Pitha, J. & Summers, R., 1 Oct 1988, In : Biochemical Pharmacology. 37, 19, p. 3601-3607 7 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Reduced glutamate binding in rat dorsal vagal complex after nodose ganglionectomy

Lewis, S. J., Verberne, A. J. M., Summers, R. J., Beart, P. M. & Cincotta, M., 1 Jan 1988, In : Brain Research Bulletin. 21, 6, p. 913-916 4 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

α1- and α2-adrenoceptors of the circular myometrium from the dioestrous guinea-pig

Haynes, J. & Pennefather, J. N., 1988, In : Clinical and Experimental Pharmacology and Physiology. 15, 9, p. 695-701 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
1987

Autoradiographic analysis of receptors on vascular endothelium

Stephenson, J. A. & Summers, R. J., 28 Jan 1987, In : European Journal of Pharmacology. 134, 1, p. 35-43 9 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Autoradiographic localization and characterization of substance P binding in dog kidney

Stephenson, J. A., Summers, R. J. & Burcher, E., 27 Oct 1987, In : European Journal of Pharmacology. 142, 3, p. 391-402 12 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Autoradiographic localization of beta-1 and beta-2 adrenoceptors in guinea pig atrium and regions of the conducting system.

Molenaar, P., Canale, E. & Summers, R. J., 1 Jun 1987, In : Journal of Pharmacology and Experimental Therapeutics. 241, 3, p. 1048-1064 17 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Autoradiographic localization of receptors in the cardiovascular system

Summers, R. J., Molenaar, P. & Stephenson, J. A., 1 Jan 1987, In : Trends in Pharmacological Sciences. 8, 7, p. 272-276 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

21 Citations (Scopus)

AUTORADIOGRAPHIC LOCALIZATION OF RECEPTORS IN THE MAMMALIAN CARDIOVASCULAR SYSTEM

Summers, R. J., Molenaar, P., Stephenson, J. A. & Jones, C. R., 1 Jan 1987, In : Clinical and Experimental Pharmacology and Physiology. 14, 5, p. 437-447 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Characterization and autoradiographic localization of β‐adrenoceptor subtypes in human cardiac tissues

Buxton, B. F., Jones, C. R., Molenaar, P. & Summers, R. J., 1 Jan 1987, In : British Journal of Pharmacology. 92, 2, p. 299-310 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
82 Citations (Scopus)

CHARACTERIZATION AND LOCALIZATION OF (—‐)[125I]‐CYANOPINDOLOL BINDING TO NON‐β‐ADRENOCEPTOR SITES IN DOG KIDNEY

Lew, R. & Summers, R. J., 1 Jan 1987, In : Clinical and Experimental Pharmacology and Physiology. 14, 9, p. 711-723 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Characterization of beta-1 and beta-2 adrenoceptors in guinea pig atrium: functional and receptor binding studies.

Molenaar, P. & Summers, R. J., 1 Jun 1987, In : Journal of Pharmacology and Experimental Therapeutics. 241, 3, p. 1041-1047 7 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

Excitatory amino acid projections to the nucleus accumbens septi in the rat: A retrograde transport study utilizing d[3H]aspartate and [3H]GABA

Christie, M. J., Summers, R. J., Stephenson, J. A., Cook, C. J. & Beart, P. M., 1 Jan 1987, In : Neuroscience. 22, 2, p. 425-439 15 p.

Research output: Contribution to journalArticleResearchpeer-review

265 Citations (Scopus)

Stimulation of α1‐adrenoceptors in rat kidney mediates increased inositol phospholipid hydrolysis

Neylon, C. B. & Summers, R. J., 1 Jan 1987, In : British Journal of Pharmacology. 91, 2, p. 367-376 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
67 Citations (Scopus)

The distribution of β-adrenoceptors in dog kidney: an autoradiographic analysis

Law, R. & Summers, R. J., 4 Aug 1987, In : European Journal of Pharmacology. 140, 1, p. 1-11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
1986

AUTORADIOGRAPHIC ANALYSIS OF (‐)‐[125I]‐CYP BINDING IN MOUSE KIDNEY

Lew, R. & Summers, R. J., 1 Jan 1986, In : Clinical and Experimental Pharmacology and Physiology. 13, 3, p. 211-221 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Autoradiographic analysis of the distribution of β‐adrenoceptors in the dog splenic vasculature

Lipe, S. & Summers, R. J., 1 Jan 1986, In : British Journal of Pharmacology. 87, 3, p. 603-609 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Autoradiographic demonstration of endothelium-dependent 125I-Bolton-Hunter substance P binding to dog carotid artery

Stephenson, J. A., Burcher, E. & Summers, R. J., 27 May 1986, In : European Journal of Pharmacology. 124, 3, p. 377-378 2 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

AUTORADIOGRAPHIC EVIDENCE FOR A HETEROGENEOUS DISTRIBUTION OF α1‐ ADRENORECEPTORS LABELLED BY [3 H] PRAZOSIN IN RAT, DOG AND HUMAN KIDNEY

STEPHENSON, JENNIFER. A. & SUMMERS, R. J., 1 Jan 1986, In : Journal of Autonomic Pharmacology. 6, 2, p. 109-116 8 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Changes in the innervation and catecholamine concentrations in the myometrium of pregnant and non-pregnant sheep1

Sigger, J. N., Harding, R. & Summers, R. J., 1 Jan 1986, In : Cells Tissues Organs. 125, 2, p. 101-107 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)