Research Output

1998

Differential regulation of β3-adrenoceptors in gut and adipose tissue of genetically obese (ob/ob) C57BL/6J-mice

Evans, B. A., Papaioannou, M., Anastasopoulos, F. & Summers, R. J., 26 Jun 1998, In : British Journal of Pharmacology. 124, 4, p. 763-771 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
24 Citations (Scopus)

Living free-radical polymerization by reversible addition - Fragmentation chain transfer: The RAFT process

Chiefari, J., Chong, Y. K., Ercole, F., Krstina, J., Jeffery, J., Le, T. P. T., Mayadunne, R. T. A., Meijs, G. F., Moad, C. L., Moad, G., Rizzardo, E. & Thang, S. H., 11 Aug 1998, In : Macromolecules. 31, 16, p. 5559-5562 4 p.

Research output: Contribution to journalArticleResearchpeer-review

4121 Citations (Scopus)

Modulation of Δ9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat

Malone, D. T. & Taylor, D. A., 15 Aug 1998, In : British Journal of Pharmacology. 124, 7, p. 1419-1424 6 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

On the unique binding and activating properties of xanomeline at the M1 muscarinic acetylcholine receptor

Christopoulos, A., Pierce, T. L., Sorman, J. L. & El-Fakahany, E. E., 1 Jun 1998, In : Molecular Pharmacology. 53, 6, p. 1120-1130 11 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Regulation of β-adrenoceptors in a rat model of cardiac failure: Effect of perindopril

Gu, X. H., Kompa, A. R. & Summers, R. J., 1 Jul 1998, In : Journal of Cardiovascular Pharmacology. 32, 1, p. 66-74 9 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

The effects of the β3-adrenoceptor agonist BRL 35135 on UCP isoform mRNA expression

Emilsson, V., Summers, R. J., Hamilton, S., Liu, Y. L. & Cawthorne, M. A., 18 Nov 1998, In : Biochemical and Biophysical Research Communications. 252, 2, p. 450-454 5 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

β3-Andrenoceptors: Differential regulation and novel subtypes

Summers, R. J., Hutchinson, D. S. & Evans, B. A., 1 Jan 1998, In : Pharmacy and Toxicology, Supplement. 83, 1, p. 37-39 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

Alternative splicing generates two isoforms of the β3-adrenoceptor which are differentially expressed in mouse tissues

Evans, B. A., Papaioannou, M., Hamilton, S. & Summers, R. J., 10 Aug 1999, In : British Journal of Pharmacology. 127, 6, p. 1525-1531 7 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

Bradykinin-stimulated protein synthesis by myocytes is dependent on the MAP kinase pathway and p70(S6K)

Ritchie, R. H., Marsh, J. D. & Schiebinger, R. J., 1 Apr 1999, In : American Journal of Physiology - Heart and Circulatory Physiology. 276, 4 45-4

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Characterization of β-adrenoceptor mediated smooth muscle relaxation and the detection of mRNA for β1-, β2- and β3-adrenoceptors in rat ileum

Roberts, S. J., Papaioannou, M., Evans, B. A. & Summers, R. J., 6 Jul 1999, In : British Journal of Pharmacology. 127, 4, p. 949-961 13 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Desensitization and resensitization of β1- and putative β4-adrenoceptor mediated responses occur in parallel in a rat model of cardiac failure

Kompa, A. R. & Summers, R. J., 1 Jan 1999, In : British Journal of Pharmacology. 128, 7, p. 1399-1406 8 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Desensitization of cardiac β-adrenoceptor signaling with heart failure produced by myocardial infarction in the rat. Evidence for the role of Gi but not Gs or phosphorylating proteins

Kompa, A. R., Gu, X. H., Evans, B. A. & Summers, R. J., 1 Jan 1999, In : Journal of Molecular and Cellular Cardiology. 31, 6, p. 1185-1201 17 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Functional analysis of desensitization of the β-adrenoceptor signalling pathway in rat cardiac tissues following chronic isoprenaline infusion

McMartin, L. & Summers, R. J., 6 Jul 1999, In : British Journal of Pharmacology. 127, 4, p. 1012-1020 9 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Imidazolidinone nitroxide-mediated polymerization

Chong, Y. K., Ercole, F., Moad, G., Rizzardo, E., Thang, S. H. & Anderson, A. G., 19 Oct 1999, In : Macromolecules. 32, 21, p. 6902-6903 2 p.

Research output: Contribution to journalArticleResearchpeer-review

83 Citations (Scopus)

Investigation of 5-HT 4 agonist activities using molecular field analysis

Iskander, M., Coupar, I. & Winkler, D. A., 1999, In : Journal of the Chemical Society, Perkin Transactions 2. 2, p. 153-158 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Separate roles for β2- and β3-adrenoceptors in memory consolidation

Gibbs, M. E. & Summers, R. J., 1 Dec 1999, In : Neuroscience. 95, 3, p. 913-922 10 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Tailored polymers by free radical processes

Rizzardo, E., Chiefari, J., Chong, B. Y. K., Ercole, F., Krstina, J., Jeffrey, J., Le, T. P. T., Mayadunne, R. T. A., Meijs, G. F., Moad, C. L., Moad, G. & Thang, S. H., 1 Jan 1999, In : Macromolecular Symposia. 143, p. 291-307 17 p.

Research output: Contribution to journalArticleResearchpeer-review

192 Citations (Scopus)
2000

Intracerebroventricular administration of the β3-adrenoceptor agonist CL 316243 causes Fos immunoreactivity in discrete regions of rat hypothalamus

Castillo-Meléndez, M., McKinley, M. J. & Summers, R. J., 1 Sep 2000, In : Neuroscience Letters. 290, 3, p. 161-164 4 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Multiple ramp domains are required for generation of amylin receptor phenotype from the calcitonin receptor gene product.

Zumpe, E. T., Tilakaratne, N., Fraser, NJ., Christopoulos, G., Foord, S. M. & Sexton, P., 7 Jan 2000, In : Biochemical and Biophysical Research Communications. 267, 1, p. 368-372

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

β3-adrenoceptor regulation and relaxation responses in mouse ileum

Hutchinson, D. S., Evans, B. A. & Summers, R. J., 1 Jan 2000, In : British Journal of Pharmacology. 129, 6, p. 1251-1259 9 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)
2001

Enhancement of memory consolidation in chicks by β3-adrenoceptor agonists

Gibbs, M. E. & Summers, R. J., 16 Feb 2001, In : European Journal of Pharmacology. 413, 2-3, p. 235-240 6 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Erratum: The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria (European Journal of Pharmacology (2001) 416 (235-244) PII: S0014299901008275)

Lanzafame, A., Christopoulos, A. & Mitchelson, F., 29 Jun 2001, In : European Journal of Pharmacology. 423, 1, p. 93-94 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

1 Citation (Scopus)

Monitoring the physiological parameters of SCI patients during rehabilitation

Brown, I., Lai, A. & Nunn, A., 2001, ANZIIS 2001 - Proceedings of the 7th Australian and New Zealand Intelligent Information Systems Conference. IEEE, Institute of Electrical and Electronics Engineers, p. 297-302 6 p. 974094

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Stimulation of α1-adrenoceptors inhibits memory consolidation in the chick

Gibbs, M. E. & Summers, R. J., 1 Dec 2001, In : European Journal of Neuroscience. 14, 8, p. 1369-1376 8 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and β3-AR knock-out mice

Heffernan, M., Summers, R. J., Thorburn, A., Ogru, E., Gianello, R., Jiang, W. J. & Ng, F. M., 1 Jan 2001, In : Endocrinology. 142, 12, p. 5182-5189 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
26 Citations (Scopus)

β1-adrenoceptors compensate for β3-adrenoceptors in ileum from β3-adrenoceptor knock-out mice

Hutchinson, D. S., Evans, B. A. & Summers, R. J., 1 Jan 2001, In : British Journal of Pharmacology. 132, 2, p. 433-442 10 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

β1- and β3-adrenoceptor mediated smooth muscle relaxation in hypothyroid rat ileum

Brown, K. J. & Summers, R. J., 16 Mar 2001, In : European Journal of Pharmacology. 415, 2-3, p. 257-263 7 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
2002

Characterization of the β-adrenoceptor subtype involved in mediation of glucose transport in L6 cells

Nevzorova, J., Bengtsson, T., Evans, B. A. & Summers, R. J., 1 Jan 2002, In : British Journal of Pharmacology. 137, 1, p. 9-18 10 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Inotropic responses to human gene 2 (B29) relaxin in a rat model of myocardial infarction (MI): Effect of pertussis toxin

Kompa, A. R., Samuel, C. S. & Summers, R. J., 1 Jan 2002, In : British Journal of Pharmacology. 137, 5, p. 710-718 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
58 Citations (Scopus)

Introduction

Sexton, P. M., 1 Jan 2002, In : Receptors and Channels. 8, 3-4, p. 135-136 2 p.

Research output: Contribution to journalEditorialOtherpeer-review

2 Citations (Scopus)

Mouse β3a and β3b-adrenoceptors expressed in Chinese hamster ovary cells display identical pharmacology but utilize distinct signalling pathways

Hutchinson, D. S., Bengtsson, T., Evans, B. A. & Summers, R. J., 1 Jan 2002, In : British Journal of Pharmacology. 135, 8, p. 1903-1914 12 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Protein kinase C and the sub-sensitivity and sub-reactivity of the diabetic rat prostate gland to noradrenaline

Ramasamy, S., Hodgson, W. C. & Ventura, S., 11 Jan 2002, In : European Journal of Pharmacology. 434, 3, p. 151-161 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Relaxin 3, a novel member of the insulin/relaxin superfamily of peptide hormones.

Bathgate, R. A. D., Scott, D. J., Samuel, C. S., Burazin, T. CD., Layfield, S., Claasz, A. A., Dawson, N. F., Ma, S., Bond, C., Summers, R. J., Wade, J. D. & Tregear, G. W., 2002, In : Biology of Reproduction.

Research output: Contribution to journalReview ArticleResearchpeer-review

The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system

Poole, D. P., Castelucci, P., Robbins, H. L., Chiocchetti, R. & Furness, J. B., 31 Oct 2002, In : Autonomic Neuroscience: Basic and Clinical. 101, 1-2, p. 39-47 9 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

The distribution of purine P2x2 receptors in the guinea-pig enteric nervous system

Castelucci, P., Robbins, H. L., Poole, D. P. & Furness, J. B., 8 Jun 2002, In : Histochemistry and Cell Biology. 117, 5, p. 415-422 8 p.

Research output: Contribution to journalArticleResearchpeer-review

99 Citations (Scopus)
2003

Evidence that two forms of choline acetyltransferase are differentially expressed in subclasses of enteric neurons

Chiocchetti, R., Poole, D. P., Kimura, H., Aimi, Y., Robbins, H. L., Castelucci, P. & Furness, J. B., 1 Jan 2003, In : Cell and Tissue Research. 311, 1, p. 11-22 12 p.

Research output: Contribution to journalArticleResearchpeer-review

82 Citations (Scopus)

Protein kinase C isoforms in the enteric nervous system

Poole, D. P., Hunne, B., Robbins, H. L. & Furness, J. B., 1 Jul 2003, In : Histochemistry and Cell Biology. 120, 1, p. 51-61 11 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)
2004

Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome

Barbara, G., Stanghellini, V., De Giorgio, R., Cremon, C., Cottrell, G., Santini, D., Pasquinelli, G., Morselli-Labate, A., Grady, E., Bunnett, N., Collins, S. & Corinaldesi, R., 2004, In : Gastroenterology. 126, 3, p. 693 - 702 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1004 Citations (Scopus)

A role for proteinase-activated receptor-1 in inflammatory bowel diseases

Vergnolle, N., Cellars, L., Mencarelli, A., Rizzo, G., Swaminathan, S., Beck, P., Steinhoff, M., Andrade-Gordon, P., Bunnett, N., Hollenberg, M., Wallace, J., Cirino, G. & Fiorucci, S., 2004, In : Journal of Clinical Investigation. 114, 10, p. 1444 - 1456 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Characterisation of the binding of [ 3H]-SB-674042, a novel nonpeptide antagonist, to the human orexin-1 receptor

Langmead, C. J., Jerman, J. C., Brough, S. J., Scott, C., Porter, R. A. & Herdon, H. J., 1 Jan 2004, In : British Journal of Pharmacology. 141, 2, p. 340-346 7 p.

Research output: Contribution to journalArticleResearchpeer-review

117 Citations (Scopus)

Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage

Scholzen, T., Steinhoff, M., Sindrilaru, A., Schwarz, A., Bunnett, N., Luger, T., Armstrong, C. A. & Ansel, J. C., 2004, In : The FASEB Journal. 18, 9, p. 1 - 22 22 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Plasminogen fragmentation and increased production of extracellular matrix-degrading proteinases are associated with serous epithelial ovarian cancer progression

Murthi, P., Barker, G., Nowell, C. J., Rice, G. E., Baker, M. S., Kalionis, B. & Quinn, M. A., 1 Jan 2004, In : Gynecologic Oncology. 92, 1, p. 80-88 9 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia

Amadesi, S., Nie, J., Vergnolle, N., Cottrell, G., Grady, E., Trevisani, M., Manni, C., Geppetti, P., McRoberts, J., Ennes, H., Davis, J., Mayer, E. & Bunnett, N., 2004, In : Journal of Neuroscience. 24, 18, p. 4300 - 4312 13 p.

Research output: Contribution to journalArticleResearchpeer-review

335 Citations (Scopus)

Protease-activated receptors: contribution to physiology and disease

Ossovskaya, V. & Bunnett, N., 2004, In : Physiological Reviews. 84, p. 579 - 621 43 p.

Research output: Contribution to journalArticleResearchpeer-review

850 Citations (Scopus)

Protease-activated receptors: protease signaling in the gastrointestinal tract

Amadesi, S. & Bunnett, N., 2004, In : Current Opinion in Pharmacology. 4, 6, p. 551 - 556 6 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Protein kinases expressed by interstitial cells of Cajal

Poole, D. P., Van Nguyen, T., Kawai, M. & Furness, J. B., 1 Jan 2004, In : Histochemistry and Cell Biology. 121, 1, p. 21-30 10 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Recycling and resensitization of the neurokinin 1 receptor

Roosterman, D., Cottrell, G., Schmidlin, F., Steinhoff, M. & Bunnett, N., 2004, In : The Journal of Biological Chemistry. 279, 29, p. 30670 - 30679 10 p.

Research output: Contribution to journalArticleResearchpeer-review

62 Citations (Scopus)

Regulation of calcitonin gene-related peptide release from rat trigeminal nucleus caudalis slices in vitro

Jenkins, D. W., Langmead, C. J., Parsons, A. A. & Strijbos, P. J., 19 Aug 2004, In : Neuroscience Letters. 366, 3, p. 241-244 4 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Trypsin IV, a novel agonist of protease-activated receptors 2 and 4

Cottrell, G., Amadesi, S., Grady, E. & Bunnett, N., 2004, In : The Journal of Biological Chemistry. 279, 14, p. 13532 - 13539 8 p.

Research output: Contribution to journalArticleResearchpeer-review

139 Citations (Scopus)
2005

Adenosine A2A and dopamine D2 heteromeric receptor complexes and their function

Fuxe, K., Ferre, S., Canals, M., Torvinen, M., Terasmaa, A., Marcellino, D., Goldberg, S., Staines, W., Jacobsen, K., Lluis, C., Woods, A., Agnati, L. & Franco, R., 2005, In : Journal of Molecular Neuroscience. 26, 2-3, p. 209 - 219 10 p.

Research output: Contribution to journalArticleResearchpeer-review

164 Citations (Scopus)