Research Output

1983

Age related changes of noradrenaline content in brain regions of spontaneously hypertensive (SHR) and normotensive wistar-Kyoto (WK) rats

Howes, L. G., Rowe, P. R., Summers, R. J. & Louis, W. J., 1 Jan 1983, In : Clinical and Experimental Hypertension. A5, 6, p. 857-874 18 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Autoradiographic localization of β-adrenoceptors in rat kidney

Summers, R. J. & Kuhar, M. J., 22 Jul 1983, In : European Journal of Pharmacology. 91, 2-3, p. 305-310 6 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Characterization of central α-adrenoceptors using 3H-clonidine and its derivatives

Jarrott, B., Louis, W. J. & Summers, R. J., 1 Jan 1983, In : Chest. 83, Suppl. 2, p. 339-340 2 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Characterization of postsynaptic α‐adrenoceptors in rat aortic strips and portal veins

Digges, K. G. & Summers, R. J., 1 Jan 1983, In : British Journal of Pharmacology. 79, 3, p. 655-665 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
80 Citations (Scopus)

Effects of yohimbine stereoisomers on contractions of rat aortic strips produced by agonists with different selectivity for α1-and α2-adrenoceptors

Digges, K. G. & Summers, R. J., 9 Dec 1983, In : European Journal of Pharmacology. 96, 1-2, p. 95-99 5 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Evidence from binding studies for α2-adrenoceptors directly associated with glomeruli from rat kidney

McPherson, G. A. & Summers, R. J., 17 Jun 1983, In : European Journal of Pharmacology. 90, 4, p. 333-341 9 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Evidence from binding studies for β1-adrenoceptors associated with glomeruli isolated from rat kidney

McPherson, G. A. & Summers, R. J., 4 Jul 1983, In : Life Sciences. 33, 1, p. 87-94 8 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

The simultaneous determination of 3,4-dihydroxyphenylethylene glycol, 3,4-dihydroxyphenylacetic acid and catecholamines in brain tissue by high performance liquid chromatography with electrochemical detection

Howes, L. G., Summers, R. J., Rowe, P. R. & Loui, W. J., 8 Aug 1983, In : Neuroscience Letters. 38, 3, p. 327-332 6 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)
1984

Age related changes of catecholamines and their metabolites in central nervous system regions of spontaneously hypertensive (SHR) and normotensive wistar-Kyoto (wky) rats:

Howes, L. G., Rowe, P. R., Summers, R. J. & Louis, W. J., 1 Jan 1984, In : Clinical and Experimental Hypertension. 6, 12, p. 2263-2277 15 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Assay of brain 3,4-dihydroxyphenylethyleneglycol (DHPG) levels by high-performance liquid chromatography with electrochemical detection. Factors affecting stability during sample preparation

Howes, L. G., Summers, R. J., Rowe, P. R. & Louis, W. J., 1 Jan 1984, In : Journal of Chromatography A. 287, C, p. 133-135 3 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Autoradiographic localization of adrenoceptors in peripheral tissues

Summers, R. J., 1 Jan 1984, In : Trends in Pharmacological Sciences. 5, C, p. 216-217 2 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Effects of Methyldopa Metabolites on Amine Transmitters and Adrenergic Receptors in Rat Brain

Louis, W. J., Conway, E., Summers, R., Beart, P. & Jarrott, B., 1 Jan 1984, In : Hypertension. 6, 5, p. 40-44 5 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Renal α adrenoceptors

Summers, R. J., 1 Dec 1984, In : Federation Proceedings. 43, 14, p. 2917-2922 6 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

69 Citations (Scopus)

The involvement of central alpha adrenoceptors in the antihypertensive actions of methyldopa and clonidine in the rat

Jarrott, B., Lewis, S., Conway, E. L., Summers, R. & Louis, W. J., 1 Jan 1984, In : Clinical and Experimental Hypertension. A6, 1-2, p. 387-400 14 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)
1985

[3H]‐rauwolscine binding to α2‐adrenoceptors in the mammalian kidney: apparent receptor heterogeneity between species

Neylon, C. B. & Summers, R. J., 1 Jan 1985, In : British Journal of Pharmacology. 85, 2, p. 349-359 11 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Autoradiographic localization of β‐adrenoceptor subtypes in guinea‐pig kidney

Lew, R. & Summers, R. J., 1 Jan 1985, In : British Journal of Pharmacology. 85, 2, p. 341-348 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
31 Citations (Scopus)

Changes in brainstem and spinal adrenoceptor binding with ageing in spontaneously hypertensive and Wistar-Kyoto rats

Howes, L. G. & Summers, R. J., 24 Jun 1985, In : Neuroscience Letters. 57, 3, p. 247-250 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Light microscopic autoradiography of the distribution of [3H]rauwolscine binding to α2-adrenoceptors in rat kidney

Stephenson, J. A. & Summers, R. J., 22 Oct 1985, In : European Journal of Pharmacology. 116, 3, p. 271-278 8 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Localization of beta adrenoceptor subtypes in rat kidney by light microscopic autoradiography

Summers, R. J., Stephenson, J. A. & Kuhar, M. J., 1 Jan 1985, In : Journal of Pharmacology and Experimental Therapeutics. 232, 2, p. 561-569 9 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

Localization of β-adrenoceptors in the rabbit ear by light microscopic autoradiography

Johnston, H. G. & Summers, R. J., 10 Sep 1985, In : European Journal of Pharmacology. 115, 1, p. 97-101 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The measurement of central noradrenergic activity in spontaneously hypertensive rats: A comparison of free 3,4-dihydroxyphenylethyleneglycol levels with FLA-63 induced noradrenaline depletion

Howes, L. G., Summers, R. J., Rowe, P. R. & Louis, W. J., 1 Jan 1985, In : Journal of Hypertension. 3, 3, p. 237-242 6 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

α2-adrenoceptors in dog kidney: Autoradiographic localization and putative functions

Summers, R. J., Stephenson, J. A., Lipe, S. & Neylon, C. B., 1 Jan 1985, In : Clinical Science. 68, SUPPL. 10

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
1986

AUTORADIOGRAPHIC ANALYSIS OF (‐)‐[125I]‐CYP BINDING IN MOUSE KIDNEY

Lew, R. & Summers, R. J., 1 Jan 1986, In : Clinical and Experimental Pharmacology and Physiology. 13, 3, p. 211-221 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Autoradiographic analysis of the distribution of β‐adrenoceptors in the dog splenic vasculature

Lipe, S. & Summers, R. J., 1 Jan 1986, In : British Journal of Pharmacology. 87, 3, p. 603-609 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
11 Citations (Scopus)

Autoradiographic demonstration of endothelium-dependent 125I-Bolton-Hunter substance P binding to dog carotid artery

Stephenson, J. A., Burcher, E. & Summers, R. J., 27 May 1986, In : European Journal of Pharmacology. 124, 3, p. 377-378 2 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

AUTORADIOGRAPHIC EVIDENCE FOR A HETEROGENEOUS DISTRIBUTION OF α1‐ ADRENORECEPTORS LABELLED BY [3 H] PRAZOSIN IN RAT, DOG AND HUMAN KIDNEY

STEPHENSON, JENNIFER. A. & SUMMERS, R. J., 1 Jan 1986, In : Journal of Autonomic Pharmacology. 6, 2, p. 109-116 8 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Changes in the innervation and catecholamine concentrations in the myometrium of pregnant and non-pregnant sheep1

Sigger, J. N., Harding, R. & Summers, R. J., 1 Jan 1986, In : Cells Tissues Organs. 125, 2, p. 101-107 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

THE INFLUENCE OF AGE AND SEX ON CARDIAC, RENAL AND CAUDAL ARTERY CATECHOLAMINE CONTENT IN SPONTANEOUSLY HYPERTENSIVE (SHR) AND WISTAR KYOTO (WKY) RATS

HOWES, L. G., SUMMERS, R. J. & LOUIS, W. J., 1 Jan 1986, In : Journal of Autonomic Pharmacology. 6, 3, p. 171-180 10 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)
1987

Autoradiographic analysis of receptors on vascular endothelium

Stephenson, J. A. & Summers, R. J., 28 Jan 1987, In : European Journal of Pharmacology. 134, 1, p. 35-43 9 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Autoradiographic localization and characterization of substance P binding in dog kidney

Stephenson, J. A., Summers, R. J. & Burcher, E., 27 Oct 1987, In : European Journal of Pharmacology. 142, 3, p. 391-402 12 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Autoradiographic localization of beta-1 and beta-2 adrenoceptors in guinea pig atrium and regions of the conducting system.

Molenaar, P., Canale, E. & Summers, R. J., 1 Jun 1987, In : Journal of Pharmacology and Experimental Therapeutics. 241, 3, p. 1048-1064 17 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)

Autoradiographic localization of receptors in the cardiovascular system

Summers, R. J., Molenaar, P. & Stephenson, J. A., 1 Jan 1987, In : Trends in Pharmacological Sciences. 8, 7, p. 272-276 5 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

21 Citations (Scopus)

AUTORADIOGRAPHIC LOCALIZATION OF RECEPTORS IN THE MAMMALIAN CARDIOVASCULAR SYSTEM

Summers, R. J., Molenaar, P., Stephenson, J. A. & Jones, C. R., 1 Jan 1987, In : Clinical and Experimental Pharmacology and Physiology. 14, 5, p. 437-447 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Characterization and autoradiographic localization of β‐adrenoceptor subtypes in human cardiac tissues

Buxton, B. F., Jones, C. R., Molenaar, P. & Summers, R. J., 1 Jan 1987, In : British Journal of Pharmacology. 92, 2, p. 299-310 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
82 Citations (Scopus)

CHARACTERIZATION AND LOCALIZATION OF (—‐)[125I]‐CYANOPINDOLOL BINDING TO NON‐β‐ADRENOCEPTOR SITES IN DOG KIDNEY

Lew, R. & Summers, R. J., 1 Jan 1987, In : Clinical and Experimental Pharmacology and Physiology. 14, 9, p. 711-723 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Characterization of beta-1 and beta-2 adrenoceptors in guinea pig atrium: functional and receptor binding studies.

Molenaar, P. & Summers, R. J., 1 Jun 1987, In : Journal of Pharmacology and Experimental Therapeutics. 241, 3, p. 1041-1047 7 p.

Research output: Contribution to journalArticleResearchpeer-review

54 Citations (Scopus)

Excitatory amino acid projections to the nucleus accumbens septi in the rat: A retrograde transport study utilizing d[3H]aspartate and [3H]GABA

Christie, M. J., Summers, R. J., Stephenson, J. A., Cook, C. J. & Beart, P. M., 1 Jan 1987, In : Neuroscience. 22, 2, p. 425-439 15 p.

Research output: Contribution to journalArticleResearchpeer-review

265 Citations (Scopus)

Stimulation of α1‐adrenoceptors in rat kidney mediates increased inositol phospholipid hydrolysis

Neylon, C. B. & Summers, R. J., 1 Jan 1987, In : British Journal of Pharmacology. 91, 2, p. 367-376 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
67 Citations (Scopus)

The distribution of β-adrenoceptors in dog kidney: an autoradiographic analysis

Law, R. & Summers, R. J., 4 Aug 1987, In : European Journal of Pharmacology. 140, 1, p. 1-11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
1988

An autoradiographic study of muscarinic cholinoceptors in blood vessels: no localization on vascular endothelium

Stephenson, J. A., Gibson, R. E. & Summers, R. J., 24 Aug 1988, In : European Journal of Pharmacology. 153, 2-3, p. 271-283 13 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Autoradiographic localization and densitometric analysis of beta-1 and beta-2 adrenoceptors in the canine left anterior descending coronary artery

Molenaar, P., Jones, C. R., McMartin, L. R. & Summers, R. J., 1 Jan 1988, In : Journal of Pharmacology and Experimental Therapeutics. 246, 1, p. 384-393 10 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Inhibition by cAMP of the phosphoinositide response to α1-adrenoceptor stimulation in rat kidney

Neylon, C. B. & Summers, R. J., 13 Apr 1988, In : European Journal of Pharmacology. 148, 3, p. 441-444 4 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Persistent β-adrenoceptor blockade with alkylating pindolol (BIM) in guinea-pig left atria and trachea

Molenaar, P., Russell, F., Pitha, J. & Summers, R., 1 Oct 1988, In : Biochemical Pharmacology. 37, 19, p. 3601-3607 7 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Reduced glutamate binding in rat dorsal vagal complex after nodose ganglionectomy

Lewis, S. J., Verberne, A. J. M., Summers, R. J., Beart, P. M. & Cincotta, M., 1 Jan 1988, In : Brain Research Bulletin. 21, 6, p. 913-916 4 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

α1- and α2-adrenoceptors of the circular myometrium from the dioestrous guinea-pig

Haynes, J. & Pennefather, J. N., 1988, In : Clinical and Experimental Pharmacology and Physiology. 15, 9, p. 695-701 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
1989

Bidirectional transport of NMDA receptor and ionophore in the vagus nerve

Cincotta, M., Beart, P. M., Summers, R. J. & Lodge, D., 24 Jan 1989, In : European Journal of Pharmacology. 160, 1, p. 167-171 5 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Biochemical characterization of an autoradiographic method for studying excitatory amino acid receptors using l-[3H]glutamate

Cincotta, M., Summers, R. J. & Beart, P. M., 15 Feb 1989, In : Analytical Biochemistry. 177, 1, p. 150-155 6 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Coexistence and localization of β 1 - and β 2 -adrenoceptors in the human heart

Summers, R. J., Molnaar, P., Russell, F., Elnatan, J., Jones, C. R., Buxton, B. F., Chang, V. & Hambley, J., 1 Jan 1989, In : European Heart Journal. 10, SUPPL. B, p. 11-21 11 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

FUNCTION, CHARACTERIZATION AND AUTORADIOGRAPHIC LOCALIZATION AND QUANTITATION OF β‐ADRENOCEPTORS IN CARDIAC TISSUES

Molenaar, P., Russell, F. D., Shimada, T. & Summers, R. J., 1 Jan 1989, In : Clinical and Experimental Pharmacology and Physiology. 16, 6, p. 529-533 5 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

NEW TOOLS FOR THE LOCALIZATION OF SECOND MESSENGER SYSTEMS

Summers, R. J. & McMartin, L. R., 1 Jan 1989, In : Clinical and Experimental Pharmacology and Physiology. 16, 6, p. 549-553 5 p.

Research output: Contribution to journalArticleResearchpeer-review