Research Output

1969

Effects of monoamine oxidase inhibitors on the hypothermia produced in cats by halothane.

Summers, R. J., 1 Jan 1969, In : British Journal of Pharmacology. 37, 2, p. 400-413 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
9 Citations (Scopus)
1971

Cat assay for the emetic action of digitalis and related glycosides (digitoxin, digoxin, lanatoside C, ouabain and calactin)

PARSONS, J. A. & SUMMERS, R. J., 1 Jan 1971, In : British Journal of Pharmacology. 42, 1, p. 143-152 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Effect of the monoamine oxidase inhibitor pargyline on the uptake of labelled noradrenaline by the cat's spleen.

Blakeley, A. G., Powis, G. & Summers, R. J., 1 Oct 1971, In : British Journal of Pharmacology. 43, 2

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
1973

An uptake process for L-noradrenaline resistant to desmethylimipramine (DMI) and 17 -estradiol in the cat spleen.

Blakeley, A. G., Powis, G. & Summers, R. J., 1 Feb 1973, In : Journal of Physiology. 229, 1

Research output: Contribution to journalArticleResearchpeer-review

Some characteristics of the uptake process in the isolated blood perfused cat spleen resistant to desmethylimipramine and 17 β oestradiol

Blakeley, A. G. H., Powis, G. & Summers, R. J., 1 Dec 1973, In : British Journal of Pharmacology. 47, 3

Research output: Contribution to journalArticleResearchpeer-review

Uptake of (L) noradrenaline in the isolated cat heart perfused with blood containing desmethylimipramine (DMI) and 17 β oestradiol (17βO)

Blakeley, A. G. H., Powis, G. & Summers, R. J., 1 Jan 1973, In : Journal of Physiology. 234, 2

Research output: Contribution to journalArticleResearchpeer-review

1974

An uptake mechanism for L‐noradrenaline in the cat spleen, associated with the nerves but distinct from uptake1

Blakeley, A. G. H., Powis, G. & Summers, R. J., 1 Apr 1974, In : The Journal of Physiology. 238, 1, p. 193-206 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
8 Citations (Scopus)
1975

Aspects of the physiology and pharmacology of adrenergic transmission in the cat's spleen

Blakeley, A. G. H. & Summers, R. J., 1 Dec 1975, In : Bulletin et Memoires de l'Academie Royale de Medecine de Belgique. 130, 4-5 6, p. 222-233 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1976

The effects of AH 5158 on metabolism of 3H(-) noradrenaline released from the cat spleen by nerve stimulation

Summers, R. J. & Tillman, J., 1 Dec 1976, In : British Journal of Pharmacology. 58, 2

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The effects of AH 5158 on the overflow of transmitter and the uptake of [3H] (-) noradrenaline in the cat spleen

Blakeley, A. G. H. & Summers, R. J., 1 Jan 1976, In : British Journal of Pharmacology. 56, 3

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)
1977

The actions of the β adrenoceptor blocking agents propranolol and metoprolol in the maximally exercised horse

Snow, D. H. & Summers, R. J., 1 Dec 1977, In : Journal of Physiology. 271, 2

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The effects of L9394 on adrenergic transmission in the cat spleen

Baco, Z. M., Blakeley, A. G. H. & Summers, R. J., 1 Jan 1977, In : British Journal of Pharmacology. 60, 2

Research output: Contribution to journalArticleResearchpeer-review

1978

Localisation of [3H]-clonidine binding in guinea pig kidney

Jarrott, B. & Summers, R. J., 1 Jan 1978, In : British Journal of Pharmacology. 64, 3

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

The pharmacology of labetalol, an α- and β-adrenoceptor blocking agent

Blakeley, A. G. H. & Summers, R. J., 1 Jan 1978, In : General Pharmacology. 9, 6, p. 399-402 4 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
1979

Interaction of clonidine metabolites with an α-adreno receptor in rat brain membranes

Jarrott, B., Louis, W. J. & Summers, R. J., 1 Jan 1979, In : Clinical and Experimental Pharmacology and Physiology. 6, 6, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

The actions of the β-adrenoceptor blocking agents propranolol and metoprolol in the maximally exercised horse

Snow, D. H., Summers, R. J. & Guy, P. S., 1 Dec 1979, In : Research in Veterinary Science. 27, 1, p. 22-29 8 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

THE CHARACTERISTICS OF [3H]‐CLONIDINE BINDING TO ANα‐ADRENOCEPTOR IN MEMBRANES FROM GUINEA‐PIG KIDNEY

JARROTT, B., LOUIS, W. J. & SUMMERS, R. J., 1 Jan 1979, In : British Journal of Pharmacology. 65, 4, p. 663-670 8 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

The effect of a series of clonidine analogues on [3H] clonidine binding in rat cerebral cortex

Jarrott, B., Louis, W. J. & Summers, R. J., 1 Jan 1979, In : Biochemical Pharmacology. 28, 1, p. 141-144 4 p.

Research output: Contribution to journalArticleResearchpeer-review

39 Citations (Scopus)
1980
Open Access
17 Citations (Scopus)

Are radioligand assays useful for identification and characterization of prejunctional receptors

Summers, R. J. & Jarrott, B., 1 Jan 1980, In : Clinical and Experimental Pharmacology and Physiology. 7, 6, p. 641-642 2 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A sensitive method for measurement of catecholamines and their metabolites in extracts of small brain areas

Rowe, P. R., Summers, R. J. & Beart, P. M., 1 Jan 1980, In : Clinical and Experimental Pharmacology and Physiology. 7, 6, p. 674-675 2 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Characterization of α-adrenoceptors in rat and guinea pig tissues using radiolabeled agonists and antagonists

Jarrott, B., Summers, R. J., Culvenor, A. J. & Louis, W. J., 1 Dec 1980, In : Circulation Research. 46, 6 II

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Characteterization of (3H)clonidine binding sites in membranes prepared from guinea pig

Summers, R. J. & McPherson, G., 1 Jan 1980, In : Clinical and Experimental Pharmacology and Physiology. 7, 6, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Displacement of [3H]clonidine binding by clonidine analogues in membranes from rat cerebral cortex

Summers, R. J., Jarrott, B. & Louis, W. J., 1 Jan 1980, In : European Journal of Pharmacology. 66, 2-3, p. 233-241 9 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Localization of [3H]clonidine binding sites in membranes prepared from guinea pig renal cortex

McPherson, G. & Summers, R. J., 1 Jan 1980, In : Clinical and Experimental Pharmacology and Physiology. 7, 6, p. 659-660 2 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Selectivity of a series of clonidine-like drugs for α1 and α2 adrenoceptors in rat brain

Summers, R. J., Jarrott, B. & Louis, W. J., 1 Jan 1980, In : Neuroscience Letters. 20, 3, p. 347-350 4 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)
1981

[3H]Prazosin and [3H]clonidine binding to α‐adrenoceptors in membranes prepared from regions of rat kidney

McPherson, G. A. & Summers, R. J., 1 Jan 1981, In : Journal of Pharmacy and Pharmacology. 33, 1, p. 189-191 3 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Alpha-adrenoceptors in rat kidney studied by 3H-clonidine and 3H-prazosin binding

Summers, R. J. & McPherson, G. A., 1 Jan 1981, In : Clinical and Experimental Pharmacology and Physiology. 8, 6

Research output: Contribution to journalArticleResearchpeer-review

Comparison of [3H]clonidine and [3H]guanfacine binding to α2 adrenoceptors in membranes from rat cerebral cortex

Summers, R. J., Jarrott, B. & Louis, W. J., 7 Aug 1981, In : Neuroscience Letters. 25, 1, p. 31-36 6 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Inhibition of phenylephrine-stimulated gluconeogenesis by chlorpromazine is mediated by α-adrenergic receptors

Tilley, L., Summers, R. J., Redgrave, T. G. & Kemp, B. E., 20 Apr 1981, In : FEBS Letters. 126, 2, p. 313-317 5 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Labeling of α2-adrenoceptors in rat cerebral cortex with 3H-guanfacine

Summers, R. J., Jarrott, B. & Louis, W. J., 1 Jan 1981, In : Clinical and Experimental Pharmacology and Physiology. 8, 6

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

PHARMACOLOGICAL INVESTIGATION OF α‐ADRENORECEPTORS IN GUINEA‐PIG SPLENIC CAPSULE

DIGGES, K. G., McPHERSON, G. A. & SUMMERS, R. J., 1 Jan 1981, In : Journal of Autonomic Pharmacology. 1, 4, p. 313-320 8 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
1982

[3H]‐GUANFACINE: A RADIOLIGAND THAT SELECTIVELY LABELS HIGH AFFINITY α2‐ADRENOCEPTOR SITES IN HOMOGENATES OF RAT BRAIN

JARROTT, BEVYN., LOUIS, WILLIAM. J. & SUMMERS, ROGER. J., 1 Jan 1982, In : British Journal of Pharmacology. 75, 2, p. 401-408 8 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Anticonvulsant effects of clonidine mediated through central α2-adrenoceptors

Papanicolaou, J., Summers, R. J., Vajda, F. J. E. & Louis, W. J., 22 Jan 1982, In : European Journal of Pharmacology. 77, 2-3, p. 163-166 4 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Anticonvulsant effects of clonidine on pentylenetetrazol (PTZ)-induced convulsions in rats

Papanicolaou, J., Summers, R. J., Vajda, F. J. E. & Louis, W. J., 1 Jan 1982, In : Clinical and Experimental Pharmacology and Physiology. 9, 4, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
25 Citations (Scopus)

CHARACTERIZATION AND LOCALIZATION OF [3H]‐CLONIDINE BINDING IN MEMBRANES PREPARED FROM GUINEA‐PIG SPLEEN

McPherson, G. A. & Summers, R. J., 1 Jan 1982, In : Clinical and Experimental Pharmacology and Physiology. 9, 1, p. 77-87 11 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Comparison of α-adrenoreceptors in aortic strips and portal veins of the rat

Digges, K. G. & Summers, R. J., 1 Jan 1982, In : Clinical and Experimental Pharmacology and Physiology. 9, 4, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Correlation between [3H]-prazosin binding and α1-adrenoceptors controlling gluconeogenesis in the rat renal cortex

McPherson, G. A. & Summers, R. J., 1 Jan 1982, In : Clinical and Experimental Pharmacology and Physiology. 9, 4, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhancement of pentylenetetrazol (PTZ) induced convulsions following clonidine withdrawal in rats

Summers, R. J., Papanicolaou, J., Vajda, F. J. E. & Louis, W. J., 1 Jan 1982, In : Neuroscience Letters. 27, Suppl. 8

Research output: Contribution to journalArticleResearchpeer-review

Localisation of [3H]clonidine binding to membranes from guinea pig renal tubules

McPherson, G. A. & Summers, R. J., 15 Feb 1982, In : Biochemical Pharmacology. 31, 4, p. 583-587 5 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

New developments in α-adrenoreceptor drugs for the treatment of hypertension

Louis, W. J., Summers, R. J., Dynon, M. & Jarrott, B., 1 Jan 1982, In : Journal of Cardiovascular Pharmacology. 4, p. S168-S171

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Radioligand studies of α-adrenoceptors in the kidney

Summers, R. J. & McPherson, G. A., 1 Jan 1982, In : Trends in Pharmacological Sciences. 3, C, p. 291-294 4 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Relationship between α-adrenoceptor selectivity and anticonvulsant activity after chronic clonidine-like drugs in rats

Louis, W. J., Papanicolaou, J., Summers, R. J. & Vajda, F. J. E., 1 Jan 1982, In : British Journal of Pharmacology. 76, Suppl.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Role of central α2 adrenoceptors in control of pentylenetetrazol (PTZ) induced convulsions in rats

Summers, R. J., Papanicolaou, J., Vajda, F. J. E. & Louis, W. J., 1 Jan 1982, In : Neuroscience Letters. 27, Suppl. 8

Research output: Contribution to journalArticleResearchpeer-review

ROLE OF CENTRAL β‐ADRENOCEPTORS IN THE CONTROL OF PENTYLENETETRAZOL‐INDUCED CONVULSIONS IN RATS

LOUIS, W. J., PAPANICOLAOU, JENNY., SUMMERS, R. J. & VAJDA, F. J. E., 1 Jan 1982, In : British Journal of Pharmacology. 75, 3, p. 441-446 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
44 Citations (Scopus)

Role of β‐adrenoceptors in the anticonvulsant effect of propranolol on leptazol‐induced convulsions in rats

Papanicolaou, J., Vajda, F. J. E., Summers, R. J. & Louis, W. J., 1 Jan 1982, In : Journal of Pharmacy and Pharmacology. 34, 2, p. 124-125 2 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

The relationship between α2-adrenoceptor selectivity and anticonvulsant effect in a series of clonidine-like drugs

Papanicolaou, J., Summers, R. J., Vajda, F. J. E. & Louis, W. J., 10 Jun 1982, In : Brain Research. 241, 2, p. 393-397 5 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

The relationship between α2-adrenoceptor selectivity and anticonvulsant effect in a series of clonidine-like drugs

Summers, R. J., Papanicolaou, J., Vajda, F. J. E. & Louis, W. J., 1 Jan 1982, In : Clinical and Experimental Pharmacology and Physiology. 9, 4, p. 473-474 2 p.

Research output: Contribution to journalArticleResearchpeer-review