Drug Discovery Biology

Projects

Projects per year 2002 2026

• 2 Curtailed
• 7 Not started
• 55 Active
• 87 Finished

Projects per year

Search results

• Active

  Targeting the cause, not the symptom: a novel approach to treat stiff vessels in high blood pressure

  Qin, C. H. & Jackson, K.

  1/04/21 → 31/03/22

  Project: Research

• Probing the role of dynamics in protein modulation of GPCR phenotype

  Sexton, P. & Josephs, T.

  25/03/21 → 24/03/24

  Project: Research

• Characterising glucose-driven myocardial subproteome in the diabetic human heart and its link to cardiomyopathy phenotype

  Ritchie, R., Greening, D. W., De Blasio, M., Zimmet, A. D. & Erickson, J.

  Heart Foundation

  1/01/21 → 31/12/22

  Project: Research

• Pericardial fat pad removal as a new strategy to treat heart failure in type 2 diabetes.

  De Blasio, M., Donner, D. & Ritchie, R.

  1/01/21 → 31/12/21

  Project: Research

• QuantStudio 7 Flex Real-Time PCR System

  Ritchie, R., Qin, C. H. & De Blasio, M.

  1/01/21 → 31/12/21

  Project: Research

• Decoding fibrotic signalling mechanisms to identify new heart failure therapeutic targets

  May, L., Foster, S. & Porrello, E. R.

  1/01/21 → 31/12/22

  Project: Research

• Understanding the mechanisms of class B GPCR-transducer coupling

  Zhao, E.

  1/01/21 → 31/12/24

  Project: Research

• Using protein structure and dynamics to facilitate drug discovery

  Thal, D.

  1/01/21 → 31/12/25

  Project: Research

• Finely tuned glutamate receptor inhibitors as novel therapeutics for neurodegenerative disorders

  Gregory, K., Bradley, S. J. & Rook, J. M.

  1/01/21 → 31/12/24

  Project: Research

• Development of novel therapies to treat obesity related metabolic diseases

  Febbraio, M.

  1/01/21 → 31/12/25

  Project: Research

• Novel tools for probing changes in membrane protein organisation in breast cancer

  Halls, M., Huang, E., Hammond, G., Cadarso Busto, V., Neild, A. & Sloan, E.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/21 → 31/12/23

  Project: Research

• Understanding GPCR signalling networks

  Halls, M.

  Equity Trustees Limited

  30/11/20 → 30/11/25

  Project: Research

• Caveospheres: A versatile peptide delivery system

  Johnston, A., Veldhuis, N., Poole, D. & Foley, M. A.

  15/09/20 → 14/09/23

  Project: Research

• Formyl peptide receptor biased agonists as novel cardioprotective agents against myocardial infarction.

  Vecchio, L.

  25/08/20 → 28/02/26

  Project: Research

• New generation direct electron detector for cryo-electron microscopy

  Ramm, G., Whisstock, J., Lucet, I., Boecking, T., Landsberg, M. J., Alexandrov, K., Dunstone, M., Curmi, P. M. G., Lawrence, M. C., Lithgow, T., Watterson, D., Sexton, P. & Hankamer, B. D.

  3/07/20 → 2/07/21

  Project: Research

• Targeting endosomal receptor signalling for superior pain relief

  Batista Gondin, A.

  Weary Dunlop Foundation

  1/07/20 → 30/06/21

  Project: Research

• Discovering new drugs for epilepsy using personalised medicine

  Kwan, P., Rollo, B., Langmead, C., Ayers, K. L. & Harris, A.

  1/06/20 → 31/05/22

  Project: Research

• Functional insights into the roles of enteric glia

  Carbone, S.

  Australian Research Council (ARC)

  4/05/20 → 3/05/25

  Project: Research

• Formyl Peptide Receptor Agonist as Novel Therapy for Hypertension

  Qin, C. H., Jackson, K. L. & Ritchie, R.

  1/04/20 → 31/03/22

  Project: Research

• Therapeutic Targeting of Formyl Peptide Receptors to Treat Cardiovascular Disease

  Qin, C. H.

  1/04/20 → 31/03/24

  Project: Research

• Exploiting Biased Agonists of Formyl Peptide Receptors as Pharmacotherapy for Pulmonary Hypertension: simultaneous targeting of vascular function and remodelling

  Qin, C. H., Jackson, K. L. & Woodman, O. L.

  1/04/20 → 31/12/22

  Project: Research

• ACCS: The Australian Characterisation Commons at Scale

  Goscinski, W., Bonnington, P., Quenette, S., Abbott, D., Abramson, D., Ali, R., Andrade, J., Barth, M., Betbeder-Matibet, L., Beves, J., Bond, C., Boyd, B., Bryant, G., Cairney, J., Colmer, T., Egan, G., Etheridge, J., Frazier, J., Galloway, G., Gentle, I., Gilbert, A., Gray, M., Hilder, E., Janke, A., Johnstone, T., Kemp, C., Lay, P., Love, S., Martinez, P. A., Mehnert, A., Moffat, B., Mulvaney, P., Raston, C. L., Thordarson, P., Weyland, M., Oijen, A. V., Sexton, P., Sullivan, R., Ward, N., Warr, G., Wepf, R., Wilson, L., Whisstock, J. & Yen, L.

  Australia's Academic and Research Network, National Imaging Facility, University of Melbourne, University of South Australia, Flinders University, Monash University – Internal University Contribution, Massive, Queensland Cyber Infrastructure Foundation Ltd (QCIF), RMIT University, University of New South Wales, University of Queensland , University of Sydney, University of Western Australia, University of Wollongong

  7/02/20 → 7/02/23

  Project: Research

• Making chemotherapy curative: Blocking neural signalling to prevent TNBC relapse

  Sloan, E., Ilomaki, J. & Botteri, E.

  1/01/20 → 30/04/23

  Project: Research

• Therapeutic Targeting to Protect the Diabetic Heart

  Ritchie, R., Murphy, M. & De Blasio, M.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/20 → 31/12/22

  Project: Research

• Molecular control of efficacy at glucagon family of receptors

  Wootten, D. & Wu, B.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/20 → 31/12/24

  Project: Research

• Developing new tools for chemical biology

  Scanlon, M., Porter, C., Halls, M. & Doak, B.

  1/01/20 → 31/12/22

  Project: Research

• Engineering new tools to aid structure determination of membrane proteins

  Thal, D., Veldhuis, N., Wang, H. & Scott, D. J.

  9/10/19 → 8/10/22

  Project: Research

• Molecular basis of activation of the prototypic class B G protein-coupled secretin receptor

  Miller, L. J. & Sexton, P.

  1/09/19 → 31/08/23

  Project: Research

• Chemical-Biology Approaches to Pathway Selective Adenosine Receptor Ligands

  Scammells, P. & Christopoulos, A.

  1/07/19 → 30/06/22

  Project: Research

• Discovering novel allosteric probes of muscarinic acetylcholine receptors

  Valant, C., Scammells, P. & Christopoulos, A.

  3/06/19 → 2/06/22

  Project: Research

• Understanding the kinetics of nanomedicine clearance from healthy and diseased lungs

  Kaminskas, L., Whittaker, M. & Whittaker, A. K.

  1/04/19 → 31/03/22

  Project: Research

• The designer cytokine IC7: a novel therapy for the treatment of type 2 Diabetes

  Febbraio, M. & Rose-John, S.

  1/02/19 → 31/12/22

  Project: Research

• Towards a better understanding of the health benefits of physical activity: designing exercise mimetic for the treatment of disease

  Febbraio, M.

  1/02/19 → 31/12/21

  Project: Research

• A structural understanding of calcitonin gene-related peptide and adrenomedullin function

  Wootten, D., Hay, D. & Liang, L.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/19 → 31/12/23

  Project: Research

• NHMRC Research Fellowship

  Sexton, P.

  1/01/19 → 31/12/23

  Project: Research

• The physiological and pathophysiological relevance of glucagon-like-peptide-1 receptor biased agonism

  Wootten, D. & Hutchinson, D.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/19 → 31/12/22

  Project: Research

• Novel targeting of the glucagon family of G protein coupled receptors

  Wootten, D.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/19 → 31/12/23

  Project: Research

• Prodrug Development of Biased N-Alkylpyridazinones for the Acute Intravenous Treatment of Myocardial Ischaemia-Reperfusion Injury

  Baell, J., Ritchie, R. H., Kirkpatrick, C., Figtree, G., Deora, G. & Qin, C. H.

  1/01/19 → 31/12/21

  Project: Research

• Translating membrane proteins into therapeutics; from bedside to bench

  Sexton, P., Christopoulos, A., Pantelis, C. & Parton, R. G.

  1/01/19 → 31/12/23

  Project: Research

• The molecular basis for efficacy at G protein coupled receptors (GPCRs)

  Furness, S.

  Australian Research Council (ARC)

  1/01/19 → 31/12/22

  Project: Research

• ICON: ICON Collaboration-Tracing health impacts of natural and added nutrients in foods – approach for next-generation validation of the function of foods

  Bennett, L., Bucking, M., McCaffrey, T., Robinson, A., Haynes, J., Williamson, G., Murray, M., Selby-Pham, S. & Coelho Marques, F.

  1/08/18 → 1/08/21

  Project: Research

• Adenosine A1 receptor modulation: Structure, dynamics & novel pharmacological interventions

  Christopoulos, A., May, L., Imlach, W., Hill, S. & Scott, D.

  1/01/18 → 31/12/22

  Project: Research

• Mechanisms of Ligand-Selective Signalling by Chemokine Receptors

  Stone, M., Canals, M., Lane, R. & Schittenhelm, R.

  1/01/18 → 31/12/21

  Project: Research

• G Protein-Coupled Receptor Context-Specific Biased Agonism to Treat Ischaemic Heart Disease

  May, L.

  Heart Foundation

  1/01/18 → 1/08/24

  Project: Research

• Discovery and Characterisation of Tick Evasins - Inhibitors of Chemokine-mediated Inflammation

  Stone, M., Payne, R., Rothenberg, M., Canals, M. & Wilce, M.

  1/01/18 → 31/12/21

  Project: Research

• Molecular determinants of drug binding and selectivity at muscarinic acetylcholine receptors

  Thal, D., Gooley, P. R. & Dror, R.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/18 → 31/12/21

  Project: Research

• Towards the rational design of calcium sensing receptor allosteric modulators for the treatment of osteoporosis and calcium handling disorders

  Leach, K., Gregory, K., Conigrave, A., Capuano, B., Kufareva, I., Thakker, R. & Hannan, F. M.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/18 → 31/12/21

  Project: Research

• IRTG: International Research Training Grant (IRTG)_Renewal of Molecular pathogenesis of male reproductive disorders project

  Meinhardt, A., Loveland, K., Bhushan, S., Ellem, S. J., Hedger, M., O'Bryan, M., O'Donnell, L., Stanton, P., Risbridger, G., Baker, M. A., Hobbs, R., Loveland, B., Exintaris, B., Western, P., McLachlan, R., Whittaker, M., Wagenlehner, F. M. E., Bergmann, M., Diemer, T., Fietz, D., Fijak, M., Konrad, L., Linn, T., Middendorff, R., Pilatz, A., Schagdarsurengin, U., Schuppe, H. C., Steger, K. & Scheiner-Bobis, G.

  1/10/17 → 31/03/22

  Project: Research

• Exploring metabotropic glutamate receptor 5 bias, allostery and heteromers

  Gregory, K.

  1/07/17 → 30/06/21

  Project: Research

• Understanding bias and allostery at the calcium sensing receptor

  Leach, K.

  Australian Research Council (ARC), Monash University

  1/01/17 → 2/12/22

  Project: Research