Drug Discovery Biology

Projects

Projects per year 2002 2013 2015 2017 2018 2019 2020 2021 2022 2023 2030

• 3 Curtailed
• 12 Not started
• 42 Active
• 188 Finished

Projects per year

Search results

• Finished

  High-resolution imaging to characterise a unique mouse model of Dystrophic Epidermolysis Bullosa (DEB)

  Veldhuis, N. (Primary Chief Investigator (PCI)), Poole, D. (Chief Investigator (CI)), Imlach, W. (Chief Investigator (CI)), Kern, J. (Chief Investigator (CI)), Eriksson, E. M. Y. (Chief Investigator (CI)) & Nguyen, N. (Chief Investigator (CI))

  1/03/24 → 25/03/25

  Project: Research

• Targeting gut ceramides - a new way to improve systemic insulin sensitivity

  Turpin-Nolan, S. (Primary Chief Investigator (PCI)) & Febbraio, M. (Chief Investigator (CI))

  15/01/24 → 14/01/25

  Project: Research

• Consortium for Research expertise in Eating Disorders (CORED)

  Sharp, G. (Primary Chief Investigator (PCI)), Langiu, M. (Chief Investigator (CI)), Ramadas, A. (Chief Investigator (CI)), Yao, C. (Chief Investigator (CI)) & Stafrace, S. (Chief Investigator (CI))

  20/11/23 → 31/12/24

  Project: Research

• NHMRC Equipment Grant - Glacios 200kV FEG Cryo Transmission Electron Microscope

  Sexton, P.

  1/11/23 → 31/12/24

  Project: Research

• Structural characterization of GLP-1 peptide agonists in complex with GLP-1R and amylin-receptor antibody in complex with amylin receptors

  Wootten, D. (Primary Chief Investigator (PCI)), Sexton, P. (Chief Investigator (CI)), Zhang, C. (Chief Investigator (CI)), Belousoff, M. (Chief Investigator (CI)), Reedtz-Runge, S. (Partner Investigator (PI)) & Glendorf, T. (Partner Investigator (PI))

  1/10/23 → 31/12/24

  Project: Research

• The Bridge and Bridgetech Industry Fellowship

  Carbone, S. (Primary Chief Investigator (PCI))

  26/09/23 → 31/12/23

  Project: Research

• Bridge REDI Fellowship

  Batista Gondin, A. (Chief Investigator (CI))

  25/09/23 → 1/11/23

  Project: Research

• Defining the cellular environment of the colon in Hirschsprung Disease

  Mahdavian, N. (Primary Chief Investigator (PCI)) & Poole, D. (Supervisor)

  Histochemical Society Inc

  1/09/23 → 30/09/24

  Project: Research

• Structure-activity-relationship analysis of lead candidates to provide insight into how the structural components of our lead candidates influence pharmacokinetics

  Scanlon, M. (Supervisor) & Konstantinidou, E. (Primary Chief Investigator (PCI))

  Psylo Pty Ltd

  15/06/23 → 19/12/23

  Project: Research

• Cryo correlative Focused Ion Beam, a new frontier in structural biology

  Hanssen, E. G. (Primary Chief Investigator (PCI)), Ghosal, D. (Chief Investigator (CI)), McFadden, G. I. (Chief Investigator (CI)), Rouiller, I. (Chief Investigator (CI)), Parker, M. W. (Chief Investigator (CI)), Ivanova, E. P. (Chief Investigator (CI)), Wootten, D. (Chief Investigator (CI)), Belousoff, M. (Chief Investigator (CI)), Lucet, I. (Partner Investigator (PI)), Czabotar, P. E. (Partner Investigator (PI)) & Bouwer, J. (Chief Investigator (CI))

  17/04/23 → 16/04/24

  Project: Research

• Characterisation of a preclinical mouse model of diabetic cardiomyopathy ready for translational investigations

  De Blasio, M. (Primary Chief Investigator (PCI)) & Ritchie, R. (Chief Investigator (CI))

  10/03/23 → 9/03/25

  Project: Research

• Navigating the commercialisation ecosystem - Experiencing the Industry Development Pathway from Preclinical to Phase III Clinical Trials

  Turpin-Nolan, S. (Primary Chief Investigator (PCI))

  16/01/23 → 23/12/23

  Project: Research

• Endothelial Cells: an Underappreciated Therapeutic Target in HFpEF

  Ritchie, R. (Primary Chief Investigator (PCI)), Figtree, G. A. (Chief Investigator (CI)), May, L. (Chief Investigator (CI)) & Qin, C. H. (Chief Investigator (CI))

  1/01/23 → 31/12/24

  Project: Research

• LIFTING THE VEIL: SEX-SPECIFIC CARDIAC BENEFITS OF NEXT-GENERATION GLUCOSE-LOWERING THERAPY

  Ritchie, R. (Primary Chief Investigator (PCI)) & De Blasio, M. (Chief Investigator (CI))

  Diabetes Australia

  1/01/23 → 30/04/25

  Project: Research

• Discovery of a lead molecule for development into a non-hormonal male contraceptive

  Mobbs, J. (Primary Chief Investigator (PCI)), Ventura, S. (Chief Investigator (CI)), Thal, D. (Chief Investigator (CI)) & Bennetts, F. (Chief Investigator (CI))

  1/01/23 → 30/04/24

  Project: Research

• Delivery of pH-responsive nanoparticles to reduce thrombo-inflammation and neural injury after ischaemic stroke

  Wong, C. (Primary Chief Investigator (PCI)), Veldhuis, N. (Chief Investigator (CI)), Whittaker, M. (Chief Investigator (CI)) & Bourne, J. (Chief Investigator (CI))

  1/01/23 → 31/12/24

  Project: Research

• TISN: Tackling ischaemic stroke with nanomedicine

  Bourne, J. (Primary Chief Investigator (PCI)), Wong, C. (Chief Investigator (CI)), Veldhuis, N. (Chief Investigator (CI)), Whittaker, M. (Chief Investigator (CI)) & Lawlor, K. (Chief Investigator (CI))

  1/01/23 → 31/03/24

  Project: Research

• Developing Novel Pro-Resolving Medicines to Treat Vulnerable Atherosclerotic Plaques

  Qin, C. H. (Primary Chief Investigator (PCI)) & Ritchie, R. (Chief Investigator (CI))

  14/09/22 → 31/03/23

  Project: Research

• Identification of new compounds targeting CAD-associated inflammation

  May, L. (Primary Chief Investigator (PCI)), TN Nguyen, A. (Chief Investigator (CI)), Drummond, G. (Chief Investigator (CI)) & Vinh, A. (Chief Investigator (CI))

  14/09/22 → 31/03/23

  Project: Research

• HSCR iPSC and Progenitor Cell Program

  Poole, D. (Primary Chief Investigator (PCI)) & Carbone, S. (Chief Investigator (CI))

  21/07/22 → 20/07/24

  Project: Research

• A high efficiency whole animal imaging system for the development of targeted cancer therapeutics

  Feeney, O. (Primary Chief Investigator (PCI)), Nowell, C. (Chief Investigator (CI)), Sloan, E. (Chief Investigator (CI)), Johnston, A. (Chief Investigator (CI)), Mueller, S. N. (Partner Investigator (PI)) & Such, G. K. (Chief Investigator (CI))

  1/07/22 → 31/12/22

  Project: Research

• RESOLVING INFLAMMATION TO TREAT DIABETIC VASCULAR REMODELLING

  Qin, C. H. (Primary Chief Investigator (PCI)), Wright, K. (Chief Investigator (CI)), Ritchie, R. (Chief Investigator (CI)) & Woodman, O. L. (Chief Investigator (CI))

  Diabetes Australia, Monash University – Internal Department Contribution

  1/06/22 → 31/05/24

  Project: Research

• Human high-throughput in-vitro phenotypic screening for new epilepsy drugs

  Rollo, B. (Primary Chief Investigator (PCI)), Kwan, P. (Chief Investigator (CI)), O'Brien, T. (Chief Investigator (CI)), Langmead, C. (Chief Investigator (CI)), Baell, J. (Chief Investigator (CI)), Casillas-Espinosa, P. (Chief Investigator (CI)), May, L. (Chief Investigator (CI)), Ayers, K. L. (Chief Investigator (CI)) & Sumer, H. (Chief Investigator (CI))

  1/06/22 → 1/01/23

  Project: Research

• Validating CaMKK2 as a Rational Treatment Target for Bipolar Disorder

  Scott, J. (Primary Chief Investigator (PCI)), Gundlach, A. L. (Chief Investigator (CI)) & Steinberg, G. R. (Chief Investigator (CI))

  National Health and Medical Research Council (NHMRC) (Australia)

  2/05/22 → 31/12/23

  Project: Research

• Developing Novel Pro-Resolving Medicines to Treat Vulnerable Atherosclerotic Plaques

  Qin, C. H. (Primary Chief Investigator (PCI)), Ritchie, R. (Chief Investigator (CI)), Karlheinz, P. (Chief Investigator (CI)) & Chen, Y.-C. (Chief Investigator (CI))

  1/04/22 → 31/03/23

  Project: Research

• Targeting cardiac adiponectin signalling as a novel treatment for cardiac lipotoxicity.

  De Blasio, M. (Primary Chief Investigator (PCI)), Anderson, D. (Chief Investigator (CI)), Ritchie, R. (Chief Investigator (CI)) & Prakoso, D. (Chief Investigator (CI))

  3/01/22 → 31/12/22

  Project: Research

• Identification of effective cannabinoid analgesics for Dystrophic Epidermolysis Bullosa (DEB)

  Veldhuis, N. (Primary Chief Investigator (PCI)), Pang, K. (Chief Investigator (CI)), Kern, J. (Chief Investigator (CI)), Smith, B. (Chief Investigator (CI)), McGregor, I. S. (Chief Investigator (CI)) & Cairns, E. (Chief Investigator (CI))

  1/01/22 → 31/12/22

  Project: Research

• Improving therapeutic delivery of RNA

  Johnston, A. (Primary Chief Investigator (PCI)), Such, G. K. (Chief Investigator (CI)), Pouton, C. (Associate Investigator (AI)), Mintern, J. D. (Associate Investigator (AI)) & Sloan, E. (Associate Investigator (AI))

  1/01/22 → 31/12/24

  Project: Research

• Role of extracellular vesicles in exercise-induced protection of liver steatosis and insulin resistance

  Febbraio, M. (Primary Chief Investigator (PCI)), Karin, M. (Chief Investigator (CI)) & Whitham, M. (Chief Investigator (CI))

  Diabetes Australia, Monash University – Internal School Contribution

  1/01/22 → 31/12/22

  Project: Research

• Exploring the value and impact of pedagogical content knowledge (PCK) for university educators’ teaching practice

  Sarkar, M. (Primary Chief Investigator (PCI)), Lazarus, M. (Chief Investigator (CI)), Wright, C. (Chief Investigator (CI)), Ilic, D. (Chief Investigator (CI)), White, P. (Chief Investigator (CI)), Thompson, C. (Chief Investigator (CI)), Maynard, N. (Chief Investigator (CI)) & Berry, A. (Chief Investigator (CI))

  1/10/21 → 31/12/23

  Project: Research

• NAMs of Gq-coupled muscarinic acetylcholine receptors

  Valant, C. & Christopoulos, A.

  Department of Defence (Australia)

  20/09/21 → 28/02/23

  Project: Research

• Revealing the mechanisms of chronic pain in dystrophic EB

  Veldhuis, N. (Primary Chief Investigator (PCI)), Pang, K. (Chief Investigator (CI)), Nyström , A. (Chief Investigator (CI)), Kern, J. (Chief Investigator (CI)), Robertson, S. J. (Chief Investigator (CI)), Edgington-Mitchell, L. (Associate Investigator (AI)), Rudd, D. (Associate Investigator (AI)) & Nowell, C. (Associate Investigator (AI))

  EB Research Network

  18/08/21 → 17/08/24

  Project: Research

• Bridge and BridgeTech Industry Fellowship

  Qin, C. H.

  2/08/21 → 31/12/21

  Project: Research

• Bridge and BridgeTech Industry Fellowship Placement

  Leach, K.

  28/07/21 → 2/09/21

  Project: Research

• A 3-photon imaging system for deep live imaging

  Mueller, S. N. (Primary Chief Investigator (PCI)), Heath, W. (Chief Investigator (CI)), Fletcher, E. L. (Chief Investigator (CI)), Stok, K. (Chief Investigator (CI)), McMillan, P. (Chief Investigator (CI)), Hickey, M. (Chief Investigator (CI)), Sloan, E. (Chief Investigator (CI)), Biro, M. (Chief Investigator (CI)), Lee, W. M. S. (Chief Investigator (CI)), Cavalieri, F. (Chief Investigator (CI)), Choi, Y. S. (Chief Investigator (CI)), Phan, T. (Partner Investigator (PI)) & Hawkins, E. (Partner Investigator (PI))

  University of Melbourne

  28/07/21 → 27/07/22

  Project: Research

• Alcohol addiction research in memory of Teaghan

  Langmead, C.

  Andrew Smith (via GoFundMe)

  12/07/21 → 12/07/22

  Project: Research

• New frontiers in personalised prevention of CAD

  Figtree, G. A. (Primary Chief Investigator (PCI)), Saheli, S. (Chief Investigator (CI)), Ritchie, R. (Chief Investigator (CI)), Nicholls, S. (Chief Investigator (CI)), Drummond, G. (Chief Investigator (CI)) & Meikle, P. J. (Chief Investigator (CI))

  1/07/21 → 30/09/22

  Project: Research

• Targeting Immune Checkpoints In Obesity-Driven HCC

  Wiede, F. (Primary Chief Investigator (PCI)), Tiganis, T. (Associate Investigator (AI)), Darcy, P. (Associate Investigator (AI)), Johnstone, R. W. (Associate Investigator (AI)), McLean, C. (Associate Investigator (AI)) & Febbraio, M. (Associate Investigator (AI))

  1/07/21 → 30/06/23

  Project: Research

• Probing the role of dynamics in protein modulation of GPCR phenotype

  Sexton, P. (Primary Chief Investigator (PCI)) & Josephs, T. (Chief Investigator (CI))

  1/06/21 → 31/12/23

  Project: Research

• Defining NF1 clinical variation at the microscale to discover new therapeutic targets

  Ellisdon, A. (Primary Chief Investigator (PCI)), Halls, M. (Chief Investigator (CI)), Schittenhelm, R. (Chief Investigator (CI)), Morand, E. (Associate Investigator (AI)), Whisstock, J. (Associate Investigator (AI)) & Sloan, E. (Associate Investigator (AI))

  1/06/21 → 31/05/24

  Project: Research

• New Biomolecular Capabilities for the Melbourne Magnetic Resonance Facility

  Gooley, P. R. (Primary Chief Investigator (PCI)), Scanlon, M. (Chief Investigator (CI)), Mackay, J. P. (Chief Investigator (CI)), Jones, O. A. H. (Chief Investigator (CI)), Komander, D. (Partner Investigator (PI)), McDevitt, C. A. (Chief Investigator (CI)), Urban, S. (Chief Investigator (CI)), Maher, M. J. (Chief Investigator (CI)), Griffin, M. (Chief Investigator (CI)), Call, M. E. (Partner Investigator (PI)), Borg, N. (Chief Investigator (CI)), Leach, K. (Chief Investigator (CI)), Gregory, K. (Chief Investigator (CI)) & Babon, J. (Partner Investigator (PI))

  7/05/21 → 6/05/22

  Project: Research

• Identification of effective antipruritic agents in Dystrophic Epidermolysis Bullosa (DEB)

  Veldhuis, N. (Primary Chief Investigator (PCI)), Pang, K. (Chief Investigator (CI)), Robertson, S. J. (Chief Investigator (CI)) & Kern, J. (Chief Investigator (CI))

  1/05/21 → 1/08/22

  Project: Research

• Characterisation of novel ligands for diabetes (Phase II & III)

  Hutchinson, D. & Summers, R.

  11/04/21 → 17/06/23

  Project: Research

• Development of approaches for orphan GPCR structure determination

  Sexton, P. (Primary Chief Investigator (PCI)), Wootten, D. (Chief Investigator (CI)), Belousoff, M. (Chief Investigator (CI)), Zhang, C. (Chief Investigator (CI)), Russell, I. C. (Chief Investigator (CI)) & Flocco, M. (Partner Investigator (PI))

  7/04/21 → 6/04/25

  Project: Research

• Optimisation of GPCR expression, purification and structure determination

  Sexton, P. (Primary Chief Investigator (PCI)), Wootten, D. (Chief Investigator (CI)), Belousoff, M. (Chief Investigator (CI)), Tovey, J. C. (Chief Investigator (CI)), Williams, P. (Partner Investigator (PI)) & Apelbaum, A. (Partner Investigator (PI))

  7/04/21 → 6/04/25

  Project: Research

• Targeting the cause, not the symptom: a novel approach to treat stiff vessels in high blood pressure

  Qin, C. H. (Primary Chief Investigator (PCI)) & Wright, K. (Chief Investigator (CI))

  1/04/21 → 31/03/22

  Project: Research

• Elucidating the transcriptomic profile of impaired glucose metabolism in diabetic female hearts

  Prakoso, D. (Primary Chief Investigator (PCI)), Ritchie, R. (Chief Investigator (CI)), Nath, A. P. (Chief Investigator (CI)), De Blasio, M. (Chief Investigator (CI)), Wende, A. (Chief Investigator (CI)) & Gregorevic, P. (Chief Investigator (CI))

  18/03/21 → 31/12/21

  Project: Research

• Naturally occurring metabotropic glutamate receptor 1 mutations in rare spinocerebellar ataxias; characterization and pharmacological manipulation

  Hellyer, S.

  National Ataxia Foundation Inc

  1/03/21 → 28/02/22

  Project: Research

• Regulatory T Cells and Kidney Disease Progression in Type 1 Diabetes

  Ekinci, E. (Primary Chief Investigator (PCI)), Rojas-Canales, D. (Chief Investigator (CI)), Joglekar, M. V. (Chief Investigator (CI)), Peña, A. S. (Chief Investigator (CI)), Qin, C. H. (Associate Investigator (AI)), Tan, M. (Chief Investigator (CI)), Deliyanti, D. (Chief Investigator (CI)), Glastras, S. (Chief Investigator (CI)), James, S. (Chief Investigator (CI)) & Bansal, A. (Chief Investigator (CI))

  17/02/21 → 23/09/22

  Project: Research

• HDX - the missing link in Victorian structural biology platforms

  Parker, M. (Primary Chief Investigator (PCI)), Rouiller, I. (Chief Investigator (CI)), Maher, M. (Chief Investigator (CI)), Sexton, P. (Chief Investigator (CI)), Gooley, P. R. (Chief Investigator (CI)), Williamson, N. A. (Chief Investigator (CI)), Peat, T. (Partner Investigator (PI)), Nebl, T. (Partner Investigator (PI)), Bathgate, R. A. D. (Partner Investigator (PI)), Garama, D. (Chief Investigator (CI)), Oakhill, J. (Chief Investigator (CI)), Kvansakul, M. (Chief Investigator (CI)), Langendorf, C. G. (Partner Investigator (PI)) & Czabotar, P. E. (Partner Investigator (PI))

  1/01/21 → 31/12/21

  Project: Research