Research Output 1975 2019

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2017
6 Citations (Scopus)

Thiol-Reactive Star Polymers Display Enhanced Association with Distinct Human Blood Components

Glass, J. J., Li, Y., De Rose, R., Johnston, A., Czuba, E. I., Khor, S. Y., Quinn, J. F., Whittaker, M. R., Davis, T. P. & Kent, S. J., 12 Apr 2017, In : ACS Applied Materials and Interfaces. 9, 14, p. 12182-12194 13 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Tocopheryl phosphate mixture (TPM) as a novel lipid-based transdermal drug delivery carrier: formulation and evaluation

Gavin, P. D., El-Tamimy, M., Keah, H. H. & Boyd, B. J., 1 Feb 2017, In : Drug Delivery and Translational Research. 7, 1, p. 53-65 13 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

Mahamad Maifiah, M. H., Creek, D. J., Nation, R. L., Forrest, A., Tsuji, B. T., Velkov, T. & Li, J., 30 Mar 2017, In : Scientific Reports. 7, 12 p., 45527.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock

Truong, V. X., Li, F., Ercole, F. & Forsythe, J. S., 2017, In : Chemical Communications. 53, 89, p. 12076-12079 4 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Well-defined hyperstar copolymers based on a thiol-yne hyperbranched core and a poly(2-oxazoline) shell for biomedical applications

Hartlieb, M., Floyd, T., Cook, A. B., Sanchez-Cano, C., Catrouillet, S., Burns, J. A. & Perrier, S., 7 Apr 2017, In : Polymer Chemistry. 8, 13, p. 2041-2054 14 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Zinc-coordination and C-peptide complexation: A potential mechanism for the endogenous inhibition of IAPP aggregation

Ge, X., Kakinen, A., Gurzov, E. N., Yang, W., Pang, L., Pilkington, E. H., Nedumpully-Govindan, P., Chen, P., Separovic, F., Davis, T. P., Ke, P. C. & Ding, F., 2017, In : Chemical Communications. 53, 68, p. 9394-9397 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2016
109 Citations (Scopus)

50 years of oral lipid-based formulations: provenance, progress and future perspectives

Feeney, O. M., Crum, M. F., McEvoy, C., Trevaskis, N., Williams, H., Pouton, C., Charman, W. N., Bergstrom, C. & Porter, C. J. H., 1 Jun 2016, In : Advanced Drug Delivery Reviews. 101, p. 167-194 27 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis

Bhuiyan, M. S., Ellett, F., Murray, G. L., Kostoulias, X., Cerqueira, G. M., Schulze, K. E., Mahamad Maifiah, M. H., Li, J., Creek, D. J., Lieschke, G. J. & Peleg, A. Y., 23 Aug 2016, In : Proceedings of the National Academy of Sciences. 113, 34, p. 9599-9604 6 p., 1523116113.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
12 Citations (Scopus)

A comparison of the pharmacokinetics and pulmonary lymphatic exposure of a generation 4 PEGylated dendrimer following intravenous and aerosol administration to rats and sheep

Ryan, G., Bischof, R., Enkhbaatar, P., McLeod, V. M., Chan, L. J., Jones, S. A., Owen, D. J., Porter, C. J. & Kaminskas, L. M., 2016, In : Pharmaceutical Research. 33, 2, p. 510-525 16 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Addition of 20-kDa PEG to insulin lispro alters absorption and decreases clearance in animals

Knadler, M. P., Nguyen, T. H., Campanale, K., de Veer, M. J., Beals, J. M., Li, S., Hansen, R., Siesky, A., Michael, M. D. & Porter, C. J. H., Dec 2016, In : Pharmaceutical Research. 33, 12, p. 2920-2929 10 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Adopting an active learning approach to teaching in a research-intensive higher education context transformed staff teaching attitudes and behaviours

White, P. J., Larson, I., Styles, K., Yuriev, E., Evans, D. R., Rangachari, P. K., Short, J. L., Exintaris, B., Malone, D. T., Davie, B., Eise, N., McNamara, K. & Naidu, S., 2016, In : Higher Education Research and Development. 35, 3, p. 619-633 15 p.

Research output: Contribution to journalArticleResearchpeer-review

A highly conserved aspartic acid residue of the chitosanase from Bacillus sp. TS is involved in the substrate binding

Zhou, Z., Zhao, S., Liu, Y., Chang, Z., Ma, Y., Li, J. & Song, J., 1 Nov 2016, In : Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology. 180, 6, p. 1167-1179 13 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

A new in vitro lipid digestion - in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations

Crum, M., Trevaskis, N., Williams, H. D., Pouton, C. W. & Porter, C. J., 2016, In : Pharmaceutical Research. 33, 4, p. 970-982 13 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

A New Methodology for Assessing Macromolecular Click Reactions and Its Application to Amine-Tertiary Isocyanate Coupling for Polymer Ligation

Gody, G., Roberts, D. A., Maschmeyer, T. & Perrier, S., 20 Apr 2016, In : Journal of the American Chemical Society. 138, 12, p. 4061-4068 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

Boetker, J. P., Rantanen, J., Arnfast, L., Doreth, M., Raijada, D., Loebmann, K., Madsen, C., Khan, J., Rades, T., Müllertz, A., Hawley, A., Thomas, D. & Boyd, B. J., 1 Mar 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

An oncogenic role for sphingosine kinase 2

Neubauer, H. A., Pham, D. H., Zebol, J. R., Moretti, P. A. B., Peterson, A. L., Leclercq, T. M., Chan, H., Powell, J. A., Pitman, M. R., Samuel, M. S., Bonder, C. S., Creek, D. J., Gliddon, B. L. & Pitson, S. M., 2016, In : Oncotarget. 7, 40, p. 64886-64899 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
8 Citations (Scopus)

A novel chemical biology approach for mapping of polymyxin lipopeptide antibody binding epitopes

Velkov, T., Yun, B., Schneider, E. K., Azad, M. A. K., Dolezal, O., Morris, F. C., Nation, R. L., Wang, J., Chen, K., Yu, H., Wang, L., Thompson, P. E., Roberts, K. D. & Li, J., 2016, In : ACS Infectious Diseases. 2, 5, p. 341-351 11 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii

Tran, T. B., Cheah, S-E., Yu, H. H., Bergen, P. J., Nation, R. L., Creek, D. J., Purcell, A., Forrest, A., Doi, Y., Song, J., Velkov, T. & Li, J., 1 Jun 2016, In : Journal of Antibiotics. 69, 6, p. 415-421 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
17 Citations (Scopus)

Antibacterial low molecular weight cationic polymers: Dissecting the contribution of hydrophobicity, chain length and charge to activity

Grace, J. L., Huang, J. X., Cheah, S-E., Truong Phuoc, N., Cooper, M. A., Li, J., Davis, T. P., Quinn, J. F., Velkov, T. & Whittaker, M. R., 2016, In : RSC Advances. 6, 19, p. 15469-15477 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Antimicrobial activity from colistin-heparin lamellar-phase complexes for the coating of biomedical devices

Tangso, K. J., Da Cunha, P. H. C. D., Spicer, P., Li, J. & Boyd, B. J., 16 Nov 2016, In : ACS Applied Materials and Interfaces. 8, 45, p. 31321-31329 9 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

An "unlikely" pair: the antimicrobial synergy of polymyxin B in combination with the cystic fibrosis transmembrane conductance regulator drugs KALYDECO and ORKAMBI

Schneider, E. K., Azad, M. A. K., Han, M-L., Zhou, Q. T., Wang, J., Huang, J. X., Cooper, M. A., Doi, Y., Baker, M. A., Bergen, P. J., Li, J. & Velkov, T., 8 Jul 2016, In : ACS Infectious Diseases. 2, 7, p. 478-488 11 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Applying surface energy derived cohesive-adhesive balance model in predicting the mixing, flow and compaction behaviour of interactive mixtures

Mangal, S., Meiser, F., Tan, G., Gengenbach, T., Morton, D. A. V. & Larson, I., 1 Jul 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 104, p. 110-116 7 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Aqueous Copper(II) Photoinduced Polymerization of Acrylates: Low Copper Concentration and the Importance of Sodium Halide Salts

Jones, G. R., Whitfield, R., Anastasaki, A. & Haddleton, D. M., 15 Jun 2016, In : Journal of the American Chemical Society. 138, 23, p. 7346-7352 7 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

A rationally optimized nanoparticle system for the delivery of RNA interference therapeutics into pancreatic tumors in vivo

Teo, J., McCarroll, J. A., Boyer, C., Youkhana, J., Sagnella, S. M., Duong, H. T. T., Liu, J., Sharbeen, G., Goldstein, D., Davis, T. P., Kavallaris, M. & Phillips, P. A., 11 Jul 2016, In : Biomacromolecules. 17, 7, p. 2337-2351 15 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Brushed polyethylene glycol and phosphorylcholine for grafting nanoparticles against protein binding

Wang, B., Blin, T., Kakinen, A., Ge, X., Pilkington, E. H., Quinn, J. F., Whittaker, M. R., Davis, T. P., Ke, P. C. & Ding, F., 7 Dec 2016, In : Polymer Chemistry. 7, 45, p. 6875-6879 5 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination

Le, C. P., Nowell, C. J., Kim-Fuchs, C., Botteri, E., Hiller, J. G., Ismail, H., Pimentel, M. A., Chai, M. G., Karnezis, T., Rotmensz, N., Renne, G., Gandini, S., Pouton, C. W., Ferrari, D., Möller, A., Stacker, S. A. & Sloan, E. K., 1 Mar 2016, In : Nature Communications. 7, 14 p., 10634.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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35 Citations (Scopus)

Colistin and polymyxin B dosage regimens against Acinetobacter baumannii: differences in activity and the emergence of resistance

Cheah, S-E., Li, J., Tsuji, B. T., Forrest, A., Bulitta, J. B. & Nation, R., 1 Jul 2016, In : Antimicrobial Agents and Chemotherapy. 60, 7, p. 3921-3933 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
20 Citations (Scopus)

Colistin-induced apoptosis of neuroblastoma-2a cells involves the generation of reactive oxygen species, mitochondrial dysfunction, and autophagy

Dai, C., Tang, S., Velkov, T. & Xiao, X., 1 Sep 2016, In : Molecular Neurobiology. 53, 7, p. 4685-4700 16 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Combinatorial pharmacodynamics of polymyxin B and tigecycline against heteroresistant Acinetobacter baumannii

Rao, G. G., Ly, N. S., Diep, J., Forrest, A., Bulitta, J. B., Holden, P. N., Nation, R. L., Li, J. & Tsuji, B., 1 Sep 2016, In : International Journal of Antimicrobial Agents. 48, 3, p. 331-336 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Comparative pharmacodynamics of four different carbapenems in combination with polymyxin B against carbapenem-resistant Acinetobacter baumannii

Lenhard, J. R., Gall, J. S., Bulitta, J. B., Thamlikitkul, V., Landersdorfer, C. B., Forrest, A., Nation, R. L., Li, J. & Tsuji, B. T., 1 Dec 2016, In : International Journal of Antimicrobial Agents. 48, 6, p. 719-724 6 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Comparison of the exposure time dependence of the activities of synthetic ozonide antimalarials and dihydroartemisinin against K13 wild-type and mutant Plasmodium falciparum strains

Yang, T., Xie, S. C., Cao, P., Giannangelo, C., McCaw, J., Creek, D. J., Charman, S. A., Klonis, N. & Tilley, L., 1 Aug 2016, In : Antimicrobial Agents and Chemotherapy. 60, 8, p. 4501-4510 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
31 Citations (Scopus)

Compound heterozygous FXN mutations and clinical outcome in Friedreich ataxia

Galea, C., Huq, A., Lockhart, P. J., Tai, G., Corben, L., Yiu, E. M., Gurrin, L. C., Lynch, D. R., Gelbard, S., Durr, A., Pousset, F., Parkinson, M., Labrum, R., Giunti, P., Perlman, S. L., Delatycki, M. & Evans-Galea, M. V., 2016, In : Annals of Neurology. 79, 3, p. 485-495 11 p.

Research output: Contribution to journalArticleResearchpeer-review

43 Citations (Scopus)

Computational prediction of formulation strategies for beyond-rule-of-5 compounds

Bergstrom, C., Charman, W. N. & Porter, C. J. H., 1 Jun 2016, In : Advanced Drug Delivery Reviews. 101, p. 6-21 16 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Conjugation of 10 kDa linear PEG onto trastuzumab Fab′ is sufficient to significantly enhance lymphatic exposure while preserving in vitro biological activity

Chan, L., Ascher, D. B., Yadav, R., Bulitta, J., Williams, C. C., Porter, C., Landersdorfer, C. & Kaminskas, L., 2016, In : Molecular Pharmaceutics. 13, 4, p. 1229-1241 13 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)
9 Citations (Scopus)

Controlled aqueous polymerization of acrylamides and acrylates and "in situ " depolymerization in the presence of dissolved CO2

Lloyd, D. J., Nikolaou, V., Collins, J. S., Waldron, C., Anastasaki, A., Bassett, S. P., Howdle, S. M., Blanazs, A., Wilson, P., Kempe, K. & Haddleton, D., 2016, In : Chemical Communications. 52, 39, p. 6533-6536 4 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Controlling integrin-based adhesion to a degradable electrospun fibre scaffold via SI-ATRP

Rodda, A. E., Ercole, F., Glattauer, V., Nisbet, D. R., Healy, K. E., Dove, A. P., Meagher, L. & Forsythe, J. S., 7 Dec 2016, In : Journal of Materials Chemistry B. 4, 45, p. 7314-7322 9 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Cyclic peptide-polymer conjugates: Grafting-to vs grafting-from

Larnaudie, S. C., Brendel, J. C., Jolliffe, K. A. & Perrier, S., 1 Apr 2016, In : Journal of Polymer Science, Part A: Polymer Chemistry. 54, 7, p. 1003-1011 9 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Deficiency in outer dense fiber 1 is a marker and potential driver of idiopathic male infertility

Hetherington, L., Schneider, E. K., DeKretser, D., Muller, C. H., Hondermarck, H., Velkov, T. & Baker, M. A., 1 Dec 2016, In : Molecular & Cellular Proteomics. 15, 12, p. 3685-3693 9 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: the use of polyol, disaccharide, polysaccharide and synthetic polymer to modify solid-state properties for glassy stabilisation

Sou, T., Forbes, R. T., Gray, J., Prankerd, R. J., Kaminskas, L. M., McIntosh, M. P. & Morton, D. A. V., 1 Jan 2016, In : Powder Technology. 287, p. 248-255 8 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Determining the size exclusion for nanoparticles in citrus leaves

Etxeberria, E., Gonzalez, P., Bhattacharya, P., Sharma, P. & Ke, P-C., 1 Jun 2016, In : HortScience. 51, 6, p. 732-737 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
21 Citations (Scopus)

Discrete copper(II)-formate complexes as catalytic precursors for photo-induced reversible deactivation polymerization

Nikolaou, V., Anastasaki, A., Brandford-Adams, F., Whitfield, R., Jones, G. R., Nurumbetov, G. & Haddleton, D. M., 7 Jan 2016, In : Polymer Chemistry. 7, 1, p. 191-197 7 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Effect of different renal function on antibacterial effects of piperacillin against Pseudomonas aeruginosa evaluated via the hollow-fibre infection model and mechanism-based modelling

Bergen, P. J., Bulitta, J. B., Kirkpatrick, C. M. J., Rogers, K. E., McGregor, M. J., Wallis, S. C., Paterson, D. L., Lipman, J., Roberts, J. A. & Landersdorfer, C. B., 1 Sep 2016, In : Journal of Antimicrobial Chemotherapy. 71, 9, p. 2509-2520 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Effect of the deformability of guest particles on the tensile strength of tablets from interactive mixtures

Mangal, S., Lakio, S., Gengenbach, T., Larson, I. & Morton, D. A. V., 5 Dec 2016, In : International Journal of Pharmaceutics. 514, 2, p. 341-352 12 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Effects of colistin on amino acid neurotransmitters and blood-brain barrier in the mouse brain

Wang, J., Yi, M., Chen, X., Muhammad, I., Liu, F., Li, R., Li, J. & Li, J., 1 May 2016, In : Neurotoxicology and Teratology. 55, p. 32-37 6 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Effects of Surface Composition on the Aerosolisation and Dissolution of Inhaled Antibiotic Combination Powders Consisting of Colistin and Rifampicin

Wang, W., Zhou, Q. T., Sun, S-P., Denman, J. A., Gengenbach, T. R., Barraud, N., Rice, S. A., Li, J., Yang, M. & Chan, H-K., 1 Mar 2016, In : The AAPS Journal. 18, 2, p. 372-384 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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