Research Output 1975 2019

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2016

Impact of preparation method and variables on the internal structure, morphology, and presence of liposomes in phytantriol-Pluronic® F127 cubosomes

Akhlaghi, S. P., Ribeiro, I. R., Boyd, B. J. & Loh, W., 1 Sep 2016, In : Colloids and Surfaces B: Biointerfaces. 145, p. 845-853 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Incorporation of an endogenous neuromodulatory lipid, oleoylethanolamide, into cubosomes: nanostructural characterization

Younus, M., Prentice, R. N., Clarkson, A. N., Boyd, B. J. & Rizwan, S. B., 6 Sep 2016, In : Langmuir: the ACS journal of surfaces and colloids. 32, 35, p. 8942-8950 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of block versus random monomer distribution on the cellular uptake of hydrophilic copolymers

Moraes, J., Peltier, R., Gody, G., Blum, M., Recalcati, S., Klok, H. A. & Perrier, S., 20 Dec 2016, In : ACS Macro Letters. 5, 12, p. 1416-1420 5 p.

Research output: Contribution to journalArticleResearch

Influenza-specific antibody-dependent phagocytosis

Ana-Sosa-Batiz, F., Vanderven, H., Jegaskanda, S., Johnston, A., Rockman, S., Laurie, K. L., Barr, I. G., Reading, P. C., Lichtfuss, M. & Kent, S. J., 2016, In : PLoS ONE. 11, 4, p. 1 - 18 18 p., e0154461.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Inhibition of hIAPP amyloid aggregation and pancreatic β-cell toxicity by OH-terminated PAMAM dendrimer

Gurzov, E., Wang, B., Pilkington, E. H., Chen, P., Kakinen, A., Stanley, W. J., Litwak, S. A., Hanssen, E. G., Davis, T. P., Ding, F. & Ke, P. C., 23 Mar 2016, In : Small. 12, 12, p. 1615-1626 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Insights into Spray Development from Metered-Dose Inhalers Through Quantitative X-ray Radiography

Mason-Smith, N., Duke, D. J., Kastengren, A. L., Stewart, P. J., Traini, D., Young, P. M., Chen, Y., Lewis, D. A., Soria, J., Edgington-Mitchell, D. & Honnery, D., 1 May 2016, In : Pharmaceutical Research. 33, 5, p. 1249-1258 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Installation of a rigid EDTA-like motif into a protein α-helix for paramagnetic NMR spectroscopy with cobalt(II) ions

Swarbrick, J. D., Ung, P., Dennis, M. L., Lee, M. D., Chhabra, S. & Graham, B., 22 Jan 2016, In : Chemistry - A European Journal. 22, 4, p. 1228-1232 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigation of the changes in aerosolization behavior between the jet-milled and spray-dried colistin powders through surface energy characterization

Jong, T., Li, J., Morton, D. A. V., Zhou, Q. T. & Larson, I., 1 Mar 2016, In : Journal of Pharmaceutical Sciences. 105, 3, p. 1156-1163 8 p.

Research output: Contribution to journalArticleResearchpeer-review

In vivo formation of cubic phase in situ after oral administration of cubic phase precursor formulation provides long duration gastric retention and absorption for poorly water-soluble drugs

Pham, A., Hong, L., Montagnat, O., Nowell, C., Nguyen, T-H. & Boyd, B. J., 4 Jan 2016, In : Molecular Pharmaceutics. 13, 1, p. 280-286 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Kinetic resolution of the interactions between agrochemical products and adjuvant systems upon mixing

Webster, G. R., Bisset, N. B., Cahill, D. M., Jones, P., Killick, A., Hawley, A. & Boyd, B. J., 10 Aug 2016, In : Journal of Agricultural and Food Chemistry. 64, 31, p. 6139-6147 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipid-based formulations can enable the model poorly water-soluble weakly basic drug cinnarizine to precipitate in an amorphous-salt form during in vitro digestion

Khan, J., Rades, T. & Boyd, B. J., 7 Nov 2016, In : Molecular Pharmaceutics. 13, 11, p. 3783-3793 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Lymphatic transport and lymphocyte targeting of a triglyceride mimetic prodrug is enhanced in a large animal model: studies in greyhound dogs

Han, S., Hu, L., Gracia, G., Quach, T., Simpson, J. S., Edwards, G. A., Trevaskis, N. L. & Porter, C. J. H., 3 Oct 2016, In : Molecular Pharmaceutics. 13, 10, p. 3351-3361 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Lyotropic liquid crystalline cubic phases as versatile host matrices for membrane-bound enzymes

Sun, W., Vallooran, J. J., Fong, W-K. & Mezzenga, R., 6 Apr 2016, In : Journal of Physical Chemistry Letters. 7, 8, p. 1507-1512 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Macromolecular hydrogen sulfide donors trigger spatiotemporally confined changes in cell signaling

Ercole, F., Mansfeld, F. M., Kavallaris, M., Whittaker, M. R., Quinn, J. F., Halls, M. L. & Davis, T. P., 11 Jan 2016, In : Biomacromolecules. 17, 1, p. 371-383 13 p.

Research output: Contribution to journalArticleResearchpeer-review

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Metabolic dysregulation induced in Plasmodium falciparum by dihydroartemisinin and other front-line antimalarial drugs

Cobbold, S. A., Chua, H. H., Nijagal, B., Creek, D. J., Ralph, S. A. & McConville, M. J., 15 Jan 2016, In : Journal of Infectious Diseases. 213, 2, p. 276-286 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolomics and lipidomics reveal perturbation of sphingolipid metabolism by a novel anti-trypanosomal 3-(oxazolo[4,5-b]pyridine-2-yl)anilide

Stoessel, D., Nowell, C. J., Jones, A. J., Ferrins, L., Ellis, K. M., Riley, J., Rahmani, R., Read, K. D., McConville, M. J., Avery, V. M., Baell, J. B. & Creek, D. J., 1 Jul 2016, In : Metabolomics. 12, 7, 14 p., 126.

Research output: Contribution to journalArticleResearchpeer-review

Metabolomics-based screening of the Malaria Box reveals both novel and established mechanisms of action

Creek, D. J., Chua, H. H., Cobbold, S. A., Nijagal, B., MacRae, J. I., Dickerman, B. K., Gilson, P. R., Ralph, S. A. & McConville, M. J., 1 Nov 2016, In : Antimicrobial Agents and Chemotherapy. 60, 11, p. 6650-6663 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Metal–phenolic supramolecular gelation

Rahim, M. A., Björnmalm, M., Suma, T., Faria, M., Ju, Y., Kempe, K., Müllner, M., Ejima, H., Stickland, A. D. & Caruso, F., 24 Oct 2016, In : Angewandte Chemie - International Edition. 55, 44, p. 13803-13807 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Methacrylic Zwitterionic, Thermoresponsive, and Hydrophilic (Co)Polymers via Cu(0)-Polymerization: The Importance of Halide Salt Additives

Simula, A., Anastasaki, A. & Haddleton, D. M., 1 Feb 2016, In : Macromolecular Rapid Communications. 37, 4, p. 356-361 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanostructured liquid crystalline particle assisted delivery of 2,4-dichlorophenoxyacetic acid to weeds, crops and model plants

Nadiminti, P. P., Rookes, J. E., Dong, Y. D. C., Sayer, C., Boyd, B. J. & Cahill, D. M., 2016, In : Crop Protection. 82, p. 17-29 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Near-atomic three-dimensional mapping for site-specific chemistry of 'superbugs'

Adineh, V. R., Marceau, R. K. W., Velkov, T., Li, J. & Fu, J., 9 Nov 2016, In : Nano Letters. 16, 11, p. 7113-7120 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Nitric oxide (NO) endows arylamine-containing block copolymers with unique photoresponsive and switchable LCST properties

Hu, J., Whittaker, M. R., Quinn, J. F. & Davis, T. P., 26 Apr 2016, In : Macromolecules. 49, 7, p. 2741-2749 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Optimization of polymyxin B in combination with doripenem to combat mutator Pseudomonas aeruginosa

Ly, N. S., Bulman, Z. P., Bulitta, J. B., Baron, C., Rao, G. G., Holden, P. N., Li, J., Sutton, M. D. & Tsuji, B. T., 1 May 2016, In : Antimicrobial Agents and Chemotherapy. 60, 5, p. 2870-2880 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Optimized method for untargeted metabolomics analysis of MDA-MB-231 breast cancer cells

Peterson, A. L., Walker, A. K., Sloan, E. K. & Creek, D. J., 1 Dec 2016, In : Metabolites. 6, 4, 16 p., 30.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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p53 mediates colistin-induced autophagy and apoptosis in PC-12 cells

Zhang, L., Xie, D., Chen, X., Hughes, M. L. R., Jiang, G., Lu, Z., Xia, C., Li, L., Wang, J., Xu, W., Sun, Y., Li, R., Wang, R., Qian, F., Li, J. & Li, J., 1 Sep 2016, In : Antimicrobial Agents and Chemotherapy. 60, 9, p. 5294-5301 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Pancreatic β-cell membrane fluidity and toxicity induced by human islet amyloid polypeptide species

Pilkington, E. H., Gurzov, E., Kakinen, A., Litwak, S. A., Stanley, W. J., Davis, T. P. & Ke, P. C., 2016, In : Scientific Reports. 6, p. 1-10 10 p., 21274.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Paradoxical effect of polymyxin B: high drug exposure amplifies resistance in Acinetobacter baumannii

Tsuji, B. T., Landersdorfer, C. B., Lenhard, J. R., Cheah, S-E., Thamlikitkul, V., Rao, G. G., Holden, P. N., Forrest, A., Bulitta, J. B., Nation, R. L. & Li, J., 1 Jul 2016, In : Antimicrobial Agents and Chemotherapy. 60, 7, p. 3913-3920 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Passive tumour targeting and extravasation of cylindrical polymer brushes in mouse xenografts

Mullner, M., Mehta, D., Nowell, C. & Porter, C. J., Mar 2016, In : Chemical Communications. 52, 58, p. 9121-9124 4 p.

Research output: Contribution to journalArticleOtherpeer-review

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Pharmacokinetics/pharmacodynamics of colistin and polymyxin B: are we there yet?

Tran, T. B., Velkov, T., Nation, R. L., Forrest, A., Tsuji, B. T., Bergen, P. J. & Li, J., 1 Dec 2016, In : International Journal of Antimicrobial Agents. 48, 6, p. 592-597 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetics of levobupivacaine following infant spinal anesthesia

Frawley, G., Hallett, B., Velkov, T. & Bjorksten, A., 1 Jun 2016, In : Pediatric Anesthesia. 26, 6, p. 575-581 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Poly(bromoethyl acrylate): A Reactive Precursor for the Synthesis of Functional RAFT Materials

Barlow, T. R., Brendel, J. C. & Perrier, S., 13 Sep 2016, In : Macromolecules. 49, 17, p. 6203-6212 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymerisation of 2-acrylamido-2-methylpropane sulfonic acid sodium salt (NaAMPS) and acryloyl phosphatidylcholine (APC) via aqueous Cu(0)-mediated radical polymerisation

Nikolaou, V., Simula, A., Droesbeke, M., Risangud, N., Anastasaki, A., Kempe, K., Wilson, P. & Haddleton, D., 14 Apr 2016, In : Polymer Chemistry. 7, 14, p. 2452-2456 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymyxin B in combination with doripenem against heteroresistant Acinetobacter baumannii: pharmacodynamics of new dosing strategies

Rao, G. G., Ly, N. S., Bulitta, J. B., Soon, R. L., San Roman, M. D., Holden, P. N., Landersdorfer, C. B., Nation, R. L., Li, J., Forrest, A. & Tsuji, B. T., 1 Nov 2016, In : Journal of Antimicrobial Chemotherapy. 71, 11, p. 3148-3156 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymyxin resistance in Acinetobacter baumannii: genetic mutations and transcriptomic changes in response to clinically relevant dosage regimens

Cheah, S-E., Johnson, M. D., Zhu, Y., Tsuji, B. T., Forrest, A., Bulitta, J., Boyce, J. D., Nation, R. L. & Li, J., 19 May 2016, In : Scientific Reports. 6, 11 p., 26233.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Population pharmacokinetics and pharmacodynamics of lumefantrine in young Ugandan children treated with artemether-lumefantrine for uncomplicated malaria

Tchaparian, E., Sambol, N. C., Arinaitwe, E., McCormack, S. A., Bigira, V., Wanzira, H., Muhindo, M., Creek, D. J., Sukumar, N., Blessborn, D., Tappero, J. W., Kakuru, A., Bergqvist, Y., Aweeka, F. T. & Parikh, S., 15 Oct 2016, In : Journal of Infectious Diseases. 214, 8, p. 1243-1251 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Porous nanostructure controls kinetics, disposition and self-assembly structure of lipid digestion products

Joyce, P., Barnes, T. J., Boyd, B. J. & Prestidge, C. A., 2016, In : RSC Advances. 6, 82, p. 78385-78395 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Preliminary consultation on preferred product characteristics of benzathine penicillin G for secondary prophylaxis of rheumatic fever

Wyber, R., Boyd, B. J., Colquhoun, S., Currie, B. J., Engel, M., Kado, J., Karthikeyan, G., Sullivan, M., Saxena, A., Sheel, M., Steer, A., Mucumbitsi, J., Zühlke, L. & Carapetis, J., 1 Oct 2016, In : Drug Delivery and Translational Research. 6, 5, p. 572-578 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Preparation of Inert Polystyrene Latex Particles as MicroRNA Delivery Vectors by Surfactant-Free RAFT Emulsion Polymerization

Poon, C. K., Tang, O., Chen, X. M., Pham, B. T. T., Gody, G., Pollock, C. A., Hawkett, B. S. & Perrier, S., 14 Mar 2016, In : Biomacromolecules. 17, 3, p. 965-973 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Pulmonary delivery of the Kv1.3-blocking peptide HsTX1[R14A] for the treatment of autoimmune diseases

Jin, L., Zhou, Q. T., Chan, H-K., Larson, I. C., Pennington, M. W., Morales, R. A. V., Boyd, B. J., Norton, R. S. & Nicolazzo, J. A., 1 Feb 2016, In : Journal of Pharmaceutical Sciences. 105, 2, p. 650-656 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Quantifying nanoparticle internalization using a high throughput internalization assay

Mann, S. K., Czuba, E., Selby, L. I., Such, G. K. & Johnston, A. P. R., 1 Oct 2016, In : Pharmaceutical Research. 33, 10, p. 2421-2432 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Quantitation of polymyxin-lipopolysaccharide interactions using an image-based fluorescent probe

McInerney, M. P., Roberts, K. D., Thompson, P. E., Li, J., Nation, R. L., Velkov, T. & Nicolazzo, J. A., 2016, In : Journal of Pharmaceutical Sciences. 105, 2, p. 1006-1010 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Rapid Synthesis of Well-Defined Polyacrylamide by Aqueous Cu(0)-Mediated Reversible-Deactivation Radical Polymerization

Jones, G. R., Li, Z., Anastasaki, A., Lloyd, D. J., Wilson, P., Zhang, Q. & Haddleton, D. M., 26 Jan 2016, In : Macromolecules. 49, 2, p. 483-489 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Relationship between the cohesion of guest particles on the flow behaviour of interactive mixtures

Mangal, S., Gengenbach, T., Millington-Smith, D., Armstrong, B., Morton, D. A. V. & Larson, I., 1 May 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 102, p. 168-177 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Resistance suppression by high-intensity, short-duration aminoglycoside exposure against hypermutable and non-hypermutable Pseudomonas aeruginosa

Rees, V. E., Bulitta, J. B., Oliver, A., Tsuji, B. T., Rayner, C. R., Nation, R. L. & Landersdorfer, C. B., 1 Nov 2016, In : Journal of Antimicrobial Chemotherapy. 71, 11, p. 3157-3167 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Selective sequence for the peptide-triggered phase transition of lyotropic liquid-crystalline structures

Liu, Q., Dong, Y-D. & Boyd, B. J., 24 May 2016, In : Langmuir: the ACS journal of surfaces and colloids. 32, 20, p. 5155-5161 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Isahak, N., Gody, G., Malins, L. R., Mitchell, N. J., Payne, R. J. & Perrier, S., 2016, In : Chemical Communications. 52, 88, p. 12952-12955 4 p.

Research output: Contribution to journalArticleOtherpeer-review

Single intravenous dose of novel flurbiprofen-loaded proniosome formulations provides prolonged systemic exposure and anti-inflammatory effect

Verma, P., Prajapati, S. K., Yadav, R., Senyschyn, D., Shea, P. R. & Trevaskis, N. L., 7 Nov 2016, In : Molecular Pharmaceutics. 13, 11, p. 3688-3699 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Stabilising cubosomes with Tween 80 as a step towards targeting lipid nanocarriers to the blood-brain barrier

Azhari, H., Strauss, M., Hook, S., Boyd, B. J. & Rizwan, S. B., 1 Jul 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 104, p. 148-155 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Stability enhancing N-terminal PEGylation of oxytocin exploiting different polymer architectures and conjugation approaches

Collins, J., Kempe, K., Wilson, P., Blindauer, C. A., McIntosh, M. P., Davis, T. P., Whittaker, M. R. & Haddleton, D. M., 8 Aug 2016, In : Biomacromolecules. 17, 8, p. 2755-2766 12 p.

Research output: Contribution to journalArticleResearchpeer-review