Research Output 1975 2019

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Differential Effects of TPM, A Phosphorylated Tocopherol Mixture, and Other Tocopherol Derivatives as Excipients for Enhancing the Solubilization of Co-Enzyme Q10 as a Lipophilic Drug During Digestion of Lipid- Based Formulations

Pham, A., Gavin, P. D., Libinaki, R., Ramirez, G., Khan, J. T. & Boyd, B. J., 1 Jan 2019, In : Current Drug Delivery. 16, 7, p. 628-636 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential functionalisation of the internal and external surfaces of carbon-stabilised nanoporous silicon

Alba, M., Robin, M., Menzies, D., Gengenbach, T. R., Prieto-Simon, B. & Voelcker, N. H., 15 Jun 2019, In : Chemical Communications. 55, 55, p. 8001-8004 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid

Faridi, A., Yang, W., Kelly, H. G., Wang, C., Faridi, P., Purcell, A. W., Davis, T. P., Chen, P., Kent, S. J. & Ke, P. C., 11 Nov 2019, In : Biomacromolecules. 20, 11, p. 4208-4217 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Differential transplacental binding of diazepam: Causes and implications

Ridd, M. J., Brown, K. F., Nation, R. L. & Collier, C. B., 1 Sep 1983, In : European Journal of Clinical Pharmacology. 24, 5, p. 595-601 7 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Differential use of autophagy by primary dendritic cells specialized in cross-presentation

Mintern, J. D., Macri, C., Chin, W. J., Panozza, S. E., Segura, E., Patterson, N. L., Zeller, P., Bourges, D., Bedoui, S., McMillan, P., Idris, A., Nowell, C. J., Brown, A., Radford, K. J., Johnston, A. & Villadangos, J. A., 2015, In : Autophagy. 11, 6, p. 906-917 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Differentiation of Rat Mesenchymal Stem Cells toward Osteogenic Lineage on Extracellular Matrix Protein Gradients

Rasi Ghaemi, S., Delalat, B., Cavallaro, A., Mierczynska-Vasilev, A., Vasilev, K. & Voelcker, N. H., 1 Sep 2019, In : Advanced Healthcare Materials. 8, 17, 11 p., 1900595.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)
Open Access
22 Citations (Scopus)

Digestion of phospholipids after secretion of bile into the duodenum changes the phase behavior of bile components

Birru, W. A., Warren, D., Ibrahim, A. M. H., Williams, H. D., Benameur, H., Porter, C. J., Chalmers, D. K. & Pouton, C. W., 2014, In : Molecular Pharmaceutics. 11, 8, p. 2825 - 2834 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes

Li, T., Nowell, C. J., Cipolla, D., Rades, T. & Boyd, B. J., 1 Apr 2019, In : Molecular Pharmaceutics. 16, 4, p. 1775-1781 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Discovery and Validation of Clinical Biomarkers of Cancer: A Review Combining Metabolomics and Proteomics

Srivastava, A. & Creek, D. J., May 2019, In : Proteomics. 19, 10, 9 p., 1700448.

Research output: Contribution to journalArticleResearchpeer-review

98 Citations (Scopus)

Discovery of 7-hydroxy-6-methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzo[b]furan (BNC105), a tubulin polymerization inhibitor with potent antiproliferative and tumor vascular disrupting properties

Flynn, B., Gurmit, G., Grobelny, D., Chaplin, J., Paul, D., Leske, A., Lavranos, T., Chalmers, D., Charman, S., Kostewicz, E., Shackleford, D., Morizzi, J., Hamel, E., Jung, K. & Kremmidiotis, G., 2011, In : Journal of Medicinal Chemistry. 54, 17, p. 6014 - 6027 14 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Discovery of CYT997: a structurally novel orally active microtubule targeting agent

Burns, C., Harte, M., Bu, X., Fantino, E., Joffe, M., Sikanyika, H., Su, S., Tranberg, C. E., Wilson, N., Charman, S. A., Shackleford, D. & Wilks, A. F., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4639 - 4642 4 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Discovery of novel benzo[ a ]phenoxazine SSJ-183 as a drug candidate for malaria

Ge, J-F., Arai, C., Yang, M., Bakar, A., Lu, J., Ismail, N. S. M., Wittlin, S., Kaiser, M., Brun, R., Charman, S. A., Nguyen, T., Morizzi, J., Itoh, I. & Ihara, M., 2010, In : ACS Medicinal Chemistry Letters. 1, 7, p. 360 - 364 5 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Discrete copper(II)-formate complexes as catalytic precursors for photo-induced reversible deactivation polymerization

Nikolaou, V., Anastasaki, A., Brandford-Adams, F., Whitfield, R., Jones, G. R., Nurumbetov, G. & Haddleton, D. M., 7 Jan 2016, In : Polymer Chemistry. 7, 1, p. 191-197 7 p.

Research output: Contribution to journalArticleResearchpeer-review

46 Citations (Scopus)

Disposition and association of the steric stabilizer Pluronic(R) F127 in lyotropic liquid crystalline nanostructured particle dispersions

Tilley, A. J., Drummond, C. J. & Boyd, B. J., 2013, In : Journal of Colloid and Interface Science. 392, 1, p. 288 - 296 9 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Disposition and crystallization of saturated fatty acid in mixed micelles of relevance to lipid digestion

Phan, S., Salentinig, S. J., Gilbert, E. P., Darwish, T., Hawley, A., Nixon-Luke, R., Bryant, G. J. & Boyd, B. J., 2015, In : Journal of Colloid and Interface Science. 449, p. 160 - 166 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Disposition of betamethasone after intramuscular administration of two formulations to pregnant women

Nation, R. L., Petersen, M. C. & Ashley, J. J., 1 Jan 1982, In : Clinical and Experimental Pharmacology and Physiology. 9, 4, 1 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Disposition of betamethasone in parturient women after intramuscular administration.

Petersen, MC., Ashley, JJ., McBride, WG. & Nation, RL., 1 Jan 1984, In : British Journal of Clinical Pharmacology. 18, 3, p. 383-392 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
29 Citations (Scopus)

Disposition of betamethasone in parturient women after intravenous administration

Petersen, M. C., Collier, C. B., Ashley, J. J., McBride, W. G. & Nation, R. L., 1 Nov 1983, In : European Journal of Clinical Pharmacology. 25, 6, p. 803-810 8 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Disposition of gemfibrozil and gemfibrozil acyl glucuronide in the rat isolated perfused liver

Sallustio, B. C., Fairchild, B. A., Shanahan, K., Evans, A. M. & Nation, R. L., 1 Sep 1996, In : Drug Metabolism and Disposition. 24, 9, p. 984-989 6 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Disposition of l-carnitine and its short-chain esters, acetyl-l-carnitine and propionyl-l-carnitine, in the rat isolated perfused liver

Evans, A. M., Mancinelli, A., Longo, A. & Nation, R. L., 19 Dec 2000, In : Drug Metabolism and Disposition. 28, 12, p. 1401-1404 4 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

Disposition of morphine and its 3- and 6-glucuronide metabolites during morphine infusion in the sheep

Milne, R. W., Sloan, P. A., McLean, C. F., Mather, L. E., Nation, R. L., Runciman, W. B., Rutten, A. J. & Somogyi, A. A., 1 Jan 1993, In : Drug Metabolism and Disposition. 21, 6, p. 1151-1156 6 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Disposition of morphine in the rat isolated perfused kidney: Concentration ranging studies

Shanahan, K. M., Evans, A. M. & Nation, R. L., 1 Sep 1997, In : Journal of Pharmacology and Experimental Therapeutics. 282, 3, p. 1518-1525 8 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Dissolution of a poorly water-soluble drug dry coated with magnesium and sodium stearate

Tay, T., Morton, D. A. V., Gengenbach, T. R. & Stewart, P. J., 2012, In : European Journal of Pharmaceutics and Biopharmaceutics. 80, 2, p. 443 - 452 10 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery

Yadav, P., McLeod, V. M., Nowell, C. J., Selby, L. I., Johnston, A. P. R., Kaminskas, L. M. & Trevaskis, N. L., 28 Feb 2018, In : Journal of Controlled Release. 272, p. 17-28 12 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Diverse ordered 3D nanostructured amphiphile self-assembly materials found in protic ionic liquids

Mulet, X., Kennedy, D., Greaves, T., Waddington, L., Hawley, A., Kirby, N. & Drummond, C., 2010, In : Journal of Physical Chemistry Letters. 1, 18, p. 2651 - 2654 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

DNA-based probes for flow cytometry analysis of endocytosis and recycling

Dumont, C. F. M., Czuba, E., Chen, M., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., 1 Apr 2017, In : Traffic. 18, 4, p. 242-249 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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32 Citations (Scopus)

DNA melting and genotoxicity induced by silver nanoparticles and graphene

Ivask, A., Voelcker, N., Seabrook, S. A., Hor, M., Kirby, J. K., Fenech, M. F., Davis, T. P. & Ke, P. C., 2015, In : Chemical Research in Toxicology. 28, 5, p. 1023-1035 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
70 Citations (Scopus)

Dosing guidance for intravenous colistin in critically ill patients

Nation, R. L., Garonzik, S. M., Thamlikitkul, V., Giamarellos-Bourboulis, E. J., Forrest, A., Paterson, D. L., Li, J. & Silveira, F. P., 2017, In : Clinical Infectious Diseases. 64, 5, p. 565-571 7 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

Dosing of colistin - back to basic PK/PD

Bergen, P., Li, J. & Nation, R., 2011, In : Current Opinion in Pharmacology. 11, 5, p. 464 - 469 6 p.

Research output: Contribution to journalArticleResearchpeer-review

47 Citations (Scopus)

Doxorubicin-conjugated PEGylated dendrimers show similar tumoricidal activity but lower systemic toxicity when compared to PEGylated liposome and solution formulations in mouse and rat tumour models

Kaminskas, L. M., McLeod, V. M., Kelly, B. D., Cullinane, C. M., Sberna, G., Williamson, M., Boyd, B. J., Owen, D. J. & Porter, C. J., 2012, In : Molecular Pharmaceutics. 9, 3, p. 422 - 432 11 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Doxorubicin Conjugation and Drug Linker Chemistry Alter the Intravenous and Pulmonary Pharmacokinetics of a PEGylated Generation 4 Polylysine Dendrimer in Rats

Leong, N. J., Mehta, D., McLeod, V. M., Kelly, B. D., Pathak, R., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Sep 2018, In : Journal of Pharmaceutical Sciences. 107, 9, p. 2509-2513 5 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Drug access to the central nervous system in Alzheimer's disease: preclinical and clinical insights

Mehta, D., Short, J. L., Hilmer, S. N. & Nicolazzo, J., 2015, In : Pharmaceutical Research. 32, 3, p. 819 - 839 21 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Drug agglomeration and dissolution - What is the influence of powder mixing?

Kale, K. P., Hapgood, K. & Stewart, P. J., 2009, In : European Journal of Pharmaceutics and Biopharmaceutics. 72, 1, p. 156 - 164 9 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Drug-binding energetics of human a-1-acid glycoprotein assessed by isothermal titration calorimetry and molecular docking simulations

Huang, J. X., Cooper, M. A., Baker, M. A., Azad, M. A. K., Nation, R. L., Li, J. & Velkov, T., 2012, In : Journal of Molecular Recognition. 25, 12, p. 642 - 656 15 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Drug conjugation to cyclic peptide-polymer self-assembling nanotubes

Blunden, B. M., Chapman, R., Danial, M., Lu, H., Jolliffe, K. A., Perrier, S. & Stenzel, M. H., 2014, In : Chemistry - A European Journal. 20, 40, p. 12745 - 12749 5 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Drug delivery: A key factor in realising the full therapeutic potential of drugs

Charman, W. N., Chan, H-K., Finnin, B. C. & Charman, S. A., 1999, In : Drug Development Research. 46, 3-4, p. 316-327 12 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)

Drug delivery to the lymphatic system

Porter, C. J., 1997, In : Critical Reviews in Therapeutic Drug Carrier Systems. p. 333 - 393 61 p.

Research output: Contribution to journalArticleResearchpeer-review

58 Citations (Scopus)

Drug disposition in mother and foetus

Morgan, D. J., 1997, In : Clinical and Experimental Pharmacology and Physiology. p. 869 - 873 5 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Drug-drug plasma protein binding interactions of ivacaftor

Schneider, E. K., Huang, J. X., Carbone, V., Baker, M. A., Azad, M. A. K., Cooper, M. A., Li, J. & Velkov, T., 2015, In : Journal of Molecular Recognition. 28, 6, p. 339 - 348 10 p.

Research output: Contribution to journalArticleResearchpeer-review

File

Drug-induced liver disease

Morgan, D. J., 1998, In : Current Practice in Medicine. p. 68 - 70 3 p.

Research output: Contribution to journalArticleOther

60 Citations (Scopus)

Drug-lactose binding aspects in adhesive mixtures: controlling performance in dry powder inhaler formulations by altering lactose carrier surfaces.

Zhou, Q. & Morton, D., 2012, In : Advanced Drug Delivery Reviews. 64, 3, p. 275 - 284 10 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Drug plasma binding and non-esterified fatty acids: methodologic considerations

Ridd, M. J., Brown, K. F., Moore, R. G. & Nation, R. L., 1 Jan 1982, In : International Journal of Pharmaceutics. 11, 1, p. 11-20 10 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

Drug release from nanomedicines: Selection of appropriate encapsulation and release methodology

Wallace, S. J., Li, J., Nation, R. L. & Boyd, B. J., 2012, In : Drug Delivery and Translational Research. 2, p. 284 - 292 9 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Drugs and breast-feeding

Nation, R. L. & Hotham, N., 1 Jan 1987, In : Medical Journal of Australia. 146, 6, p. 308-313 6 p.

Research output: Contribution to journalArticleResearchpeer-review

147 Citations (Scopus)

Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations

Kaukonen, A. M., Boyd, B. J., Porter, C. J. H. & Charman, W. N., 2004, In : Pharmaceutical Research. 21, 2, p. 245 - 253 9 p.

Research output: Contribution to journalArticleResearchpeer-review

93 Citations (Scopus)

Drug solubilization behaviour during in vitro digestion of suspension formulations of poorly water-soluble drugs in triglyceride lipids

Kaukonen, A. M., Boyd, B. J., Charman, W. N. & Porter, C. J. H., 2004, In : Pharmaceutical Research. 21, 2, p. 254 - 260 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Drug targeting--current aspects and future prospects: J Clin Hosp Pharm

Pouton, C. W., 1985, In : Journal of clinical and hospital pharmacy. 10, p. 45-58 14 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2)

Nicolazzo, J. & Katneni, K., 2009, In : Current Topics in Medicinal Chemistry. 9, 2, p. 130 - 147 18 p.

Research output: Contribution to journalArticleResearchpeer-review