Research Output 1975 2019

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2017

Self-assembly and disassembly of stimuli responsive tadpole-like single chain nanoparticles using a switchable hydrophilic/hydrophobic boronic acid cross-linker

Zhang, J., Tanaka, J., Gurnani, P., Wilson, P., Hartlieb, M. & Perrier, S., 28 Jul 2017, In : Polymer Chemistry. 8, 28, p. 4079-4087 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Sequence Control as a Powerful Tool for Improving the Selectivity of Antimicrobial Polymers

Kuroki, A., Sangwan, P., Qu, Y., Peltier, R., Sanchez-Cano, C., Moat, J., Dowson, C. G., Williams, E. G. L., Locock, K. E. S., Hartlieb, M. & Perrier, S., 22 Nov 2017, In : ACS Applied Materials and Interfaces. 9, 46, p. 40117-40126 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Sequence-controlled methacrylic multiblock copolymers via sulfur-free RAFT emulsion polymerization

Engelis, N. G., Anastasaki, A., Nurumbetov, G., Truong, N. P., Nikolaou, V., Shegiwal, A., Whittaker, M. R., Davis, T. & Haddleton, D. M., 1 Feb 2017, In : Nature Chemistry. 9, 2, p. 171-178 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Silver-assisted development and imaging of fingermarks on non-porous and porous surfaces

Moule, E. C., Guinan, T. M., Gustafsson, O. J. R., Kobus, H., Kirkbride, K. P. & Voelcker, N. H., Nov 2017, In : International Journal of Mass Spectrometry. 422, p. 27-31 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Single Cell Level Quantification of Nanoparticle-Cell Interactions Using Mass Cytometry

Ivask, A., Mitchell, A. J., Hope, C. M., Barry, S. C., Lombi, E. & Voelcker, N. H., 15 Aug 2017, In : Analytical Chemistry. 89, 16, p. 8228-8232 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Single-step coprocessing of cohesive powder via mechanical dry coating for direct tablet compression

Qu, L., Stewart, P. J., Hapgood, K. P., Lakio, S., Morton, D. A. V. & Zhou, Q. T., 1 Jan 2017, In : Journal of Pharmaceutical Sciences. 106, 1, p. 159-167 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Singlet Oxygen Detection on a Nanostructured Porous Silicon Thin Film via Photonic Luminescence Enhancements

Jenie, S. N. A., Plush, S. E. & Voelcker, N. H., 5 Sep 2017, In : Langmuir: the ACS journal of surfaces and colloids. 33, 35, p. 8606-8613 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Soft polyhedral particles based on cubic liquid crystalline emulsion droplets

Wang, H., Zetterlund, P. B., Boyer, C., Boyd, B. J., Prescott, S. W. & Spicer, P. T., 2017, In : Soft Matter. 13, 45, p. 8492-8501 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Specific and Differential Binding of N-Acetylgalactosamine Glycopolymers to the Human Macrophage Galactose Lectin and Asialoglycoprotein Receptor

Tanaka, J., Gleinich, A. S., Zhang, Q., Whitfield, R., Kempe, K., Haddleton, D., Davis, T. P., Perrier, S., Mitchell, D. A. & Wilson, P., 8 May 2017, In : Biomacromolecules. 18, 5, p. 1624-1633 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Specification of murine ground state pluripotent stem cells to regional neuronal populations

Alsanie, W. F., Niclis, J. C., Hunt, C. P., De Luzy, I. R., Penna, V., Bye, C. R., Pouton, C. W., Haynes, J., Firas, J., Thompson, L. H. & Parish, C. L., 22 Nov 2017, In : Scientific Reports. 7, 1, 16 p., 16001.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation

Pilkington, E. H., Lai, M., Ge, X., Stanley, W. J., Wang, B., Wang, M., Kakinen, A., Sani, M-A., Whittaker, M. R., Gurzov, E. N., Ding, F., Quinn, J., Davis, T. P. & Ke, P. C., 11 Dec 2017, In : Biomacromolecules. 18, 12, p. 4249-4260 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Stathmin mediates neuroblastoma metastasis in a tubulin-independent manner via RhoA/ROCK signaling and enhanced transendothelial migration

Fife, CM., Sagnella, SM., Teo, WS., Po'uha, ST., Byrne, FL., Yeap, YYC., Ng, DCH., Davis, TP., McCarroll, JA. & Kavallaris, M., 26 Jan 2017, In : Oncogene. 36, 4, p. 501-511 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Stepwise Light-Induced Dual Compaction of Single-Chain Nanoparticles

Claus, T. K., Zhang, J., Martin, L., Hartlieb, M., Mutlu, H., Perrier, S., Delaittre, G. & Barner-Kowollik, C., 1 Aug 2017, In : Macromolecular Rapid Communications. 38, 16, 7 p., 1700264.

Research output: Contribution to journalArticleResearchpeer-review

Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana

Mwenechanya, R., Kovářová, J., Dickens, N. J., Manikhandan, M., Herzyk, P., Vincent, I. M., Weidt, S. K., Burgess, K. E., Burchmore, R. J. S., Pountain, A. W., Smith, T. K., Creek, D. J., Kim, D-H., Lepesheva, G. I. & Barrett, M. P., 16 Jun 2017, In : PLoS Neglected Tropical Diseases. 11, 6, 21 p., e0005649.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Strategies to analyse data obtained from liquid intrusion experiments of loose porous materials

Tan, G., Mortona, D. A. V. & Larson, I., 25 Oct 2017, In : Journal of Pharmaceutical and Biomedical Analysis. 145, p. 711-717 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Student engagement with a flipped classroom teaching design affects pharmacology examination performance in a manner dependent on question type

White, P. J., Naidu, S., Yuriev, E., Short, J. L., McLaughlin, J. E. & Larson, I. C., 2017, In : American Journal of Pharmaceutical Education. 81, 9, p. 10-23 14 p., 5931.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Substantial impact of altered pharmacokinetics in critically Ill patients on the antibacterial effects of meropenem evaluated via the dynamic hollow-fiber infection model

Bergen, P. J., Bulitta, J. B., Kirkpatrick, C. M. J., Rogers, K. E., McGregor, M. J., Wallis, S. C., Paterson, D. L., Nation, R. L., Lipman, J., Roberts, J. A. & Landersdorfer, C. B., 1 May 2017, In : Antimicrobial Agents and Chemotherapy. 61, 5, 14 p., e02642.

Research output: Contribution to journalArticleResearchpeer-review

Substantial targeting advantage achieved by pulmonary administration of colistin methanesulfonate in a large-animal model

Landersdorfer, C., Nguyen, T-H., Lieu, L. T., Nguyen, G., Bischof, R., Meeusen, E., Li, J., Nation, R. & McIntosh, M., 1 Jan 2017, In : Antimicrobial Agents and Chemotherapy. 61, 1, 15 p., e01934-16.

Research output: Contribution to journalArticleResearchpeer-review

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SuFEx-a selectively triggered chemistry for fast, efficient and equimolar polymer-polymer coupling reactions

Brendel, J. C., Martin, L., Zhang, J. & Perrier, S., 28 Dec 2017, In : Polymer Chemistry. 8, 48, p. 7475-7485 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Surfactant-free RAFT emulsion polymerization using a novel biocompatible thermoresponsive polymer

Truong, N. P., Quinn, J. F., Anastasaki, A., Rolland, M., Vu, M. N., Haddleton, D. M., Whittaker, M. R. & Davis, T., 28 Feb 2017, In : Polymer Chemistry. 8, 8, p. 1353-1363 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis of star polymers by RAFT polymerization as versatile nanoparticles for biomedical applications

Hu, J., Qiao, R., Whittaker, M. R., Quinn, J. F. & Davis, T. P., 2017, In : Australian Journal of Chemistry. 70, 11, p. 1161-1170 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Tailoring Cellular Uptake and Fluorescence of Poly(2-oxazoline)-Based Nanogels

Hartlieb, M., Bus, T., Kübel, J., Pretzel, D., Hoeppener, S., Leiske, M. N., Kempe, K., Dietzek, B. & Schubert, U. S., 19 Apr 2017, In : Bioconjugate Chemistry. 28, 4, p. 1229-1235 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Templated polymer replica nanoparticles to facilitate assessment of material-dependent pharmacokinetics and biodistribution

Song, D., Cui, J., Sun, H., Nguyen, T. H., Alcantara, S., De Rose, R., Kent, S. J., Porter, C. J. H. & Caruso, F., 1 Jan 2017, In : ACS Applied Materials and Interfaces. 9, 39, p. 33683-33694 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The brassinosteroid receptor BRI1 can generate cGMP enabling cGMP-dependent downstream signaling

Wheeler, J. I., Wong, A., Marondedze, C., Groen, A. J., Kwezi, L., Freihat, L., Vyas, J., Raji, M. A., Irving, H. R. & Gehring, C., 1 Aug 2017, In : The Plant Journal. 91, 4, p. 590-600 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity

Mountford, S. J., Mohanty, B., Roberts, K. D., Yu, H. H., Scanlon, M. J., Nation, R. L., Velkov, T., Li, J. & Thompson, P. E., 2017, In : Organic and Biomolecular Chemistry. 15, 34, p. 7173-7180 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Thermal study of polyester networks based on renewable monomers citric acid and gluconolactone

de Jongh, P. A. J. M., Paul, P. K. C., Khoshdel, E., Wilson, P., Kempe, K. & Haddleton, D., 1 Jan 2017, In : Polymer International. 66, 1, p. 59-63 5 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of lecithin degradation on the pH dependent stability of halofantrine encapsulated fat nano-emulsions

Haidar, I., Harding, I. H., Bowater, I. C., Eldridge, D. S. & Charman, W. N., 7 Aug 2017, In : International Journal of Pharmaceutics. 528, 1-2, p. 524-535 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The thermodynamics of Pr55Gag-RNA interaction regulate the assembly of HIV

Tanwar, H. S., Khoo, K., Garvey, M., Waddington, L., Leis, A., Hijnen, M., Velkov, T., Dumsday, G. J., McKinstry, W. J. & Johnson, M., 1 Feb 2017, In : PLoS Pathogens. 13, 2, 24 p., e1006221.

Research output: Contribution to journalArticleResearchpeer-review

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The use of microfluidics in cytotoxicity and nanotoxicity experiments

McCormick, S. C., Kriel, F. H., Ivask, A., Tong, Z., Lombi, E., Voelcker, N. H. & Priest, C., 12 Apr 2017, In : Micromachines. 8, 4, 18 p., 124.

Research output: Contribution to journalArticleResearchpeer-review

Thiol-reactive (co)polymer scaffolds comprising organic arsenical acrylamides

Footman, C., De Jongh, P. A. J. M., Tanaka, J., Peltier, R., Kempe, K., Davis, T. P. & Wilson, P., 2017, In : Chemical Communications. 53, 60, p. 8447-8450 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Thiol-Reactive Star Polymers Display Enhanced Association with Distinct Human Blood Components

Glass, J. J., Li, Y., De Rose, R., Johnston, A., Czuba, E. I., Khor, S. Y., Quinn, J. F., Whittaker, M. R., Davis, T. P. & Kent, S. J., 12 Apr 2017, In : ACS Applied Materials and Interfaces. 9, 14, p. 12182-12194 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Tocopheryl phosphate mixture (TPM) as a novel lipid-based transdermal drug delivery carrier: formulation and evaluation

Gavin, P. D., El-Tamimy, M., Keah, H. H. & Boyd, B. J., 1 Feb 2017, In : Drug Delivery and Translational Research. 7, 1, p. 53-65 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii

Mahamad Maifiah, M. H., Creek, D. J., Nation, R. L., Forrest, A., Tsuji, B. T., Velkov, T. & Li, J., 30 Mar 2017, In : Scientific Reports. 7, 12 p., 45527.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Visible-light-mediated cleavage of polymer chains under physiological conditions via quinone photoreduction and trimethyl lock

Truong, V. X., Li, F., Ercole, F. & Forsythe, J. S., 2017, In : Chemical Communications. 53, 89, p. 12076-12079 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Well-defined hyperstar copolymers based on a thiol-yne hyperbranched core and a poly(2-oxazoline) shell for biomedical applications

Hartlieb, M., Floyd, T., Cook, A. B., Sanchez-Cano, C., Catrouillet, S., Burns, J. A. & Perrier, S., 7 Apr 2017, In : Polymer Chemistry. 8, 13, p. 2041-2054 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Zinc-coordination and C-peptide complexation: A potential mechanism for the endogenous inhibition of IAPP aggregation

Ge, X., Kakinen, A., Gurzov, E. N., Yang, W., Pang, L., Pilkington, E. H., Nedumpully-Govindan, P., Chen, P., Separovic, F., Davis, T. P., Ke, P. C. & Ding, F., 2017, In : Chemical Communications. 53, 68, p. 9394-9397 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2016

50 years of oral lipid-based formulations: provenance, progress and future perspectives

Feeney, O. M., Crum, M. F., McEvoy, C., Trevaskis, N., Williams, H., Pouton, C., Charman, W. N., Bergstrom, C. & Porter, C. J. H., 1 Jun 2016, In : Advanced Drug Delivery Reviews. 101, p. 167-194 27 p.

Research output: Contribution to journalArticleResearchpeer-review

Acinetobacter baumannii phenylacetic acid metabolism influences infection outcome through a direct effect on neutrophil chemotaxis

Bhuiyan, M. S., Ellett, F., Murray, G. L., Kostoulias, X., Cerqueira, G. M., Schulze, K. E., Mahamad Maifiah, M. H., Li, J., Creek, D. J., Lieschke, G. J. & Peleg, A. Y., 23 Aug 2016, In : Proceedings of the National Academy of Sciences. 113, 34, p. 9599-9604 6 p., 1523116113.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A comparison of the pharmacokinetics and pulmonary lymphatic exposure of a generation 4 PEGylated dendrimer following intravenous and aerosol administration to rats and sheep

Ryan, G., Bischof, R., Enkhbaatar, P., McLeod, V. M., Chan, L. J., Jones, S. A., Owen, D. J., Porter, C. J. & Kaminskas, L. M., 2016, In : Pharmaceutical Research. 33, 2, p. 510-525 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Addition of 20-kDa PEG to insulin lispro alters absorption and decreases clearance in animals

Knadler, M. P., Nguyen, T. H., Campanale, K., de Veer, M. J., Beals, J. M., Li, S., Hansen, R., Siesky, A., Michael, M. D. & Porter, C. J. H., Dec 2016, In : Pharmaceutical Research. 33, 12, p. 2920-2929 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Adopting an active learning approach to teaching in a research-intensive higher education context transformed staff teaching attitudes and behaviours

White, P. J., Larson, I., Styles, K., Yuriev, E., Evans, D. R., Rangachari, P. K., Short, J. L., Exintaris, B., Malone, D. T., Davie, B., Eise, N., McNamara, K. & Naidu, S., 2016, In : Higher Education Research and Development. 35, 3, p. 619-633 15 p.

Research output: Contribution to journalArticleResearchpeer-review

A highly conserved aspartic acid residue of the chitosanase from Bacillus sp. TS is involved in the substrate binding

Zhou, Z., Zhao, S., Liu, Y., Chang, Z., Ma, Y., Li, J. & Song, J., 1 Nov 2016, In : Applied Biochemistry and Biotechnology - Part A Enzyme Engineering and Biotechnology. 180, 6, p. 1167-1179 13 p.

Research output: Contribution to journalArticleResearchpeer-review

A new in vitro lipid digestion - in vivo absorption model to evaluate the mechanisms of drug absorption from lipid-based formulations

Crum, M., Trevaskis, N., Williams, H. D., Pouton, C. W. & Porter, C. J., 2016, In : Pharmaceutical Research. 33, 4, p. 970-982 13 p.

Research output: Contribution to journalArticleResearchpeer-review

A New Methodology for Assessing Macromolecular Click Reactions and Its Application to Amine-Tertiary Isocyanate Coupling for Polymer Ligation

Gody, G., Roberts, D. A., Maschmeyer, T. & Perrier, S., 20 Apr 2016, In : Journal of the American Chemical Society. 138, 12, p. 4061-4068 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Anhydrate to hydrate solid-state transformations of carbamazepine and nitrofurantoin in biorelevant media studied in situ using time-resolved synchrotron X-ray diffraction

Boetker, J. P., Rantanen, J., Arnfast, L., Doreth, M., Raijada, D., Loebmann, K., Madsen, C., Khan, J., Rades, T., Müllertz, A., Hawley, A., Thomas, D. & Boyd, B. J., 1 Mar 2016, In : European Journal of Pharmaceutics and Biopharmaceutics. 100, p. 119-127 9 p.

Research output: Contribution to journalArticleResearchpeer-review

An oncogenic role for sphingosine kinase 2

Neubauer, H. A., Pham, D. H., Zebol, J. R., Moretti, P. A. B., Peterson, A. L., Leclercq, T. M., Chan, H., Powell, J. A., Pitman, M. R., Samuel, M. S., Bonder, C. S., Creek, D. J., Gliddon, B. L. & Pitson, S. M., 2016, In : Oncotarget. 7, 40, p. 64886-64899 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A novel chemical biology approach for mapping of polymyxin lipopeptide antibody binding epitopes

Velkov, T., Yun, B., Schneider, E. K., Azad, M. A. K., Dolezal, O., Morris, F. C., Nation, R. L., Wang, J., Chen, K., Yu, H., Wang, L., Thompson, P. E., Roberts, K. D. & Li, J., 2016, In : ACS Infectious Diseases. 2, 5, p. 341-351 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Anthelmintic closantel enhances bacterial killing of polymyxin B against multidrug-resistant Acinetobacter baumannii

Tran, T. B., Cheah, S-E., Yu, H. H., Bergen, P. J., Nation, R. L., Creek, D. J., Purcell, A., Forrest, A., Doi, Y., Song, J., Velkov, T. & Li, J., 1 Jun 2016, In : Journal of Antibiotics. 69, 6, p. 415-421 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access