Drug Delivery Disposition & Dynamics

Research Output 1975 2019

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62 Citations (Scopus)

Cubosomes containing the adjuvants imiquimod and monophosphoryl lipid A stimulate robust cellular and humoral immune responses

Rizwan, S. B., McBurney, W. T., Young, K., Hanley, T. L., Boyd, B. J., Rades, T. & Hook, S., 2013, In : Journal of Controlled Release. 165, 1, p. 16 - 21 6 p.

Research output: Contribution to journal › Article › Research › peer-review

17 Citations (Scopus)

Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis

Dai, C., Ciccotosto, G. D., Cappai, R., Tang, S., Li, D., Xie, S., Xiao, X. & Velkov, T., 2018, In : Molecular Neurobiology. 55, 1, p. 421-434 14 p.

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution

Larnaudie, S. C., Sanchis, J., Nguyen, T. H., Peltier, R., Catrouillet, S., Brendel, J. C., Porter, C. J. H., Jolliffe, K. A. & Perrier, S., 1 Sep 2018, In : Biomaterials. 178, p. 570-582 13 p.

Research output: Contribution to journal › Article › Research › peer-review

21 Citations (Scopus)

Cyclic peptide-polymer conjugates: Grafting-to vs grafting-from

Larnaudie, S. C., Brendel, J. C., Jolliffe, K. A. & Perrier, S., 1 Apr 2016, In : Journal of Polymer Science, Part A: Polymer Chemistry. 54, 7, p. 1003-1011 9 p.

Research output: Contribution to journal › Article › Research › peer-review

17 Citations (Scopus)

Cyclic Peptide-Polymer Nanotubes as Efficient and Highly Potent Drug Delivery Systems for Organometallic Anticancer Complexes

Larnaudie, S. C., Brendel, J. C., Romero-Canelón, I., Sanchez-Cano, C., Catrouillet, S., Sanchis, J., Coverdale, J. P. C., Song, J. I., Habtemariam, A., Sadler, P. J., Jolliffe, K. A. & Perrier, S., 8 Jan 2018, In : Biomacromolecules. 19, 1, p. 239-247 9 p.

Research output: Contribution to journal › Article › Research › peer-review

23 Citations (Scopus)

CYT997: a novel orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo

Burns, C., Fantino, E., Phillips, I. D., Su, S., Harte, M., Bukczynska, P. E., Frazzetto, M., Joffe, M., Kruszelnicki, I., Wang, B., Wang, Y., Wilson, N., Dilley, R. J., Wan, S. S., Charman, S. A., Shackleford, D., Fida, R., Malcontenti-Wilson, C. & Wilks, A. F., 2009, In : Molecular Cancer Therapeutics. 8, 11, p. 3036 - 3045 10 p.

Research output: Contribution to journal › Article › Research › peer-review

7 Citations (Scopus)

De-agglomeration of micronized benzodiazepines in dissolution media measured by laser diffraction particle sizing

Zhao, F-Y. & Stewart, P. J., 2003, In : Journal of Pharmacy and Pharmacology. 55, 6, p. 749 - 755 7 p.

Research output: Contribution to journal › Article › Research › peer-review

33 Citations (Scopus)

Deaggregation during the dissolution of benzodiazepines in interactive mixtures

Liu, J. & Stewart, P. J., 1998, In : Journal of Pharmaceutical Sciences. p. 1632 - 1638 7 p.

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Deficiency in outer dense fiber 1 is a marker and potential driver of idiopathic male infertility

Hetherington, L., Schneider, E. K., DeKretser, D., Muller, C. H., Hondermarck, H., Velkov, T. & Baker, M. A., 1 Dec 2016, In : Molecular & Cellular Proteomics. 15, 12, p. 3685-3693 9 p.

Research output: Contribution to journal › Article › Research › peer-review

28 Citations (Scopus)

Defining the mechanisms by which the reactive oxygen species by-product, 4-hydroxynonenal, affects human sperm cell function

Baker, M. A., Weinberg, A. S., Hetherington, L., Villaverde, A-I., Velkov, T., Baell, J. B. & Gordon, C. P., 2015, In : Biology of Reproduction. 92, 4, p. 1 - 10 10 p.

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Degradation of berenil (diminazene aceturate) in acidic aqueous solution

Campbell, M., Prankerd, R. J., Davie, A. S. & Charman, W. N., 2004, In : Journal of Pharmacy and Pharmacology. 56, 10, p. 1327 - 1332 6 p.

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Degradation of recombinant porcine growth hormone in the presence of guanidine hydrochloride

McCrossin, L. E., Charman, W. N. & Charman, S. A., 30 Oct 1998, In : International Journal of Pharmaceutics. 173, 1-2, p. 157-170 14 p.

Research output: Contribution to journal › Article › Research › peer-review

53 Citations (Scopus)

Delivering nitric oxide with nanoparticles

Quinn, J. F., Whittaker, M. R. & Davis, T. P., 2015, In : Journal of Controlled Release. 205, p. 190-205 16 p.

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma

Tong, W. Y., Alnakhli, M., Bhardwaj, R., Apostolou, S., Sinha, S., Fraser, C., Kuchel, T., Kuss, B. & Voelcker, N. H., 13 Apr 2018, In : Journal of Nanobiotechnology. 16, 1, 17 p., 38.

Research output: Contribution to journal › Article › Research › peer-review

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94 Citations (Scopus)

Dendrimer pharmacokinetics: the effect of size, structure and surface characteristics on ADME properties

Kaminskas, L., Boyd, B. & Porter, C., 2011, In : Nanomedicine. 6, 6, p. 1063 - 1084 22 p.

Research output: Contribution to journal › Article › Research › peer-review

Deposition of aminomalononitrile-based films: Kinetics, chemistry, and morphology

Toh, R. J., Evans, R., Thissen, H., Voelcker, N. H., D'ischia, M. & Ball, V., 30 Jul 2019, In : Langmuir. 35, 30, p. 9896-9903 8 p.

Research output: Contribution to journal › Article › Research › peer-review

11 Citations (Scopus)

Desbutylhalofantrine: evaluation of QT prolongation and other cardiovascular effects after intravenous administration in vivo

McIntosh, M. P., Batey, A. J., Porter, C. J. H., Charman, W. N. & Coker, S. J., 2003, In : Journal of Cardiovascular Pharmacology. 41, 3, p. 406 - 413 8 p.

Research output: Contribution to journal › Article › Research › peer-review

29 Citations (Scopus)

Design, synthesis, and evaluation of a new fluorescent probe for measuring polymyxin-lipopolysaccharide binding interactions

Soon, R., Velkov, T., Chiu, F., Thompson, P., Kancharla, R., Roberts, K., Larson, I., Nation, R. & Li, J., 2011, In : Analytical Biochemistry. 409, 2, p. 273 - 283 11 p.

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Design, synthesis and thermal behaviour of a series of well-defined clickable and triggerable sulfonate polymers

Kolomanska, J., Johnston, P., Gregori, A., Fraga-Dominguez, I., Egelhaaf, H-J., Perrier, S., Rivaton, A., Dagron-Lartigau, C. & Topham, P. D., 2015, In : RSC Advances. 5, 82, p. 66554 - 66562 9 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access
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1 Citation (Scopus)

Design and evaluation of novel polymyxin fluorescent probes

Yun, B., Roberts, K. D., Thompson, P. E., Nation, R. L., Velkov, T. & Li, J., 11 Nov 2017, In : Sensors. 17, 11, 8 p., 2598.

Research output: Contribution to journal › Article › Research › peer-review

Open Access
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11 Citations (Scopus)

Designing a multicomponent spray-dried formulation platform for pulmonary delivery of biomacromolecules: The effect of polymers on the formation of an amorphous matrix for glassy state stabilization of biomacromolecules

Sou, T., McIntosh, M. P., Kaminskas, L. M., Prankerd, R. J. & Morton, D. A. V., 2013, In : Drying Technology. 31, 13-14, p. 1451 - 1458 8 p.

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Designing a multi-component spray-dried formulation platform for pulmonary delivery of biopharmaceuticals: the use of polyol, disaccharide, polysaccharide and synthetic polymer to modify solid-state properties for glassy stabilisation

Sou, T., Forbes, R. T., Gray, J., Prankerd, R. J., Kaminskas, L. M., McIntosh, M. P. & Morton, D. A. V., 1 Jan 2016, In : Powder Technology. 287, p. 248-255 8 p.

Research output: Contribution to journal › Article › Research › peer-review

57 Citations (Scopus)

Determination of lamotrigine in human plasma by high-performance liquid chromatography

Angelis-Stoforidis, P., Morgan, D. J., O'Brien, T. J. & Vajda, F. J. E., 30 Apr 1999, In : Journal of Chromatography B: Biomedical Sciences and Applications. 727, 1-2, p. 113-118 6 p.

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Determination of naloxone in blood by high-performance liquid chromatography

Asali, L. A., Nation, R. L. & Brown, K. F., 1 Jan 1983, In : Journal of Chromatography B: Biomedical Sciences and Applications. 278, C, p. 329-335 7 p.

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Determination of physical and chemical stability in pressurised metered dose inhalers: potential new techniques

Ooi, J., Traini, D., Boyd, B. J., Gaisford, S. & Young, P. M., 2015, In : Expert Opinion on Drug Delivery. 12, 10, p. 1661-1675 15 p.

Research output: Contribution to journal › Article › Research › peer-review

28 Citations (Scopus)

Determination of ritodrine in blood and plasma by high-performance liquid chromatography with fluorescence detection

Gross, A. S., Brown, K. F., Baird-Lambert, J. A. & Nation, R. L., 1 Jan 1987, In : Journal of Chromatography B: Biomedical Sciences and Applications. 416, C, p. 400-408 9 p.

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Determination of the dihydrocodeine metabolites, dihydromorphine and nordihydrocodeine, in hepatic microsomal incubations by high-performance liquid chromatography

Kirkwood, L. C., Nation, R. L. & Somogyi, A. A., 7 Nov 1997, In : Journal of Chromatography B: Biomedical Applications. 701, 1, p. 129-134 6 p.

Research output: Contribution to journal › Article › Research › peer-review

49 Citations (Scopus)

Determination of the polar and total surface energy distributions of particulates by inverse gas chromatography

Das, S., Larson, I., Morton, D. & Stewart, P., 2011, In : Langmuir: the ACS journal of surfaces and colloids. 27, 2, p. 521 - 523 3 p.

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Determining the size exclusion for nanoparticles in citrus leaves

Etxeberria, E., Gonzalez, P., Bhattacharya, P., Sharma, P. & Ke, P-C., 1 Jun 2016, In : HortScience. 51, 6, p. 732-737 6 p.

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Deuterated phytantriol – A versatile compound for probing material distribution in liquid crystalline lipid phases using neutron scattering

Yepuri, N. R., Clulow, A. J., Prentice, R. N., Gilbert, E. P., Hawley, A., Rizwan, S. B., Boyd, B. J. & Darwish, T. A., 15 Jan 2019, In : Journal of Colloid and Interface Science. 534, p. 399-407 9 p.

Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)

Developing a framework for objective structured clinical examinations using the nominal group technique

Hussainy, S., Crum, M. F., White, P., Larson, I., Malone, D., Manallack, D., Nicolazzo, J., McDowell, J., Lim, A. & Kirkpatrick, C., 2016, In : American Journal of Pharmaceutical Education. 80, 9, 10 p., 158.

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Development and application of a micro-capillary rheometer for in-vitro evaluation of parenteral injectability

Allahham, A., Mainwaring, D. E., Stewart, P. J. & Marriott, J. L., 2004, In : Journal of Pharmacy and Pharmacology. 56, 6, p. 709 - 716 8 p.

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Development and evaluation of a topical anti-inflammatory preparation containing Dodonaea polyandra extract

Simpson, B. S., Luo, X., Wang, J., Song, Y., Claudie, D. J., Garg, S., Smith, N. M., McKinnon, R. A. & Semple, S. J., 2015, In : Journal of Pharmacy and Pharmaceutical Sciences. 18, 4, p. 578-599 22 p.

Research output: Contribution to journal › Article › Research › peer-review

Open Access
24 Citations (Scopus)

Development and validation of a liquid chromatography-mass spectrometry assay for polymyxin B in bacterial growth media

Cheah, S-E., Bulitta, J. B., Li, J. & Nation, R. L., 2014, In : Journal of Pharmaceutical and Biomedical Analysis. 92, p. 177 - 182 6 p.

Research output: Contribution to journal › Article › Research › peer-review

4 Citations (Scopus)

Development and validation of an in-cell western for quantifying P-glycoprotein expression in human brain microvascular endothelial (hCMEC/D3) cells

McInerney, M. P., Pan, Y., Short, J. L. & Nicolazzo, J. A., Sep 2017, In : Journal of Pharmaceutical Sciences. 106, 9, p. 2614-2624 11 p.

Research output: Contribution to journal › Article › Research › peer-review

8 Citations (Scopus)

Development of a Gemcitabine-Polymer Conjugate with Prolonged Cytotoxicity against a Pancreatic Cancer Cell Line

Joubert, F., Martin, L., Perrier, S. & Pasparakis, G., 16 May 2017, In : ACS Macro Letters. 6, 5, p. 535-540 6 p.

Research output: Contribution to journal › Article › Research › peer-review

19 Citations (Scopus)

Development of an oral formulation for oestrone 3-O-sulphamate, a potent sulphatase inhibitor

Sahm, U. G., Williams, G. J., Purohit, A., Hidalgo Aragones, M. I., Parish, D., Reed, M. J., Potter, B. V. L. & Pouton, C. W., 1 Dec 1996, In : Pharmaceutical Sciences. 2, 1, p. 17-20 4 p.

Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)

Development of a Shape-Controlled H2S Delivery System Using Epoxide-Functional Nanoparticles

Yu, S. H., Esser, L., Khor, S. Y., Senyschyn, D., Veldhuis, N. A., Whittaker, M. R., Ercole, F., Davis, T. P. & Quinn, J. F., 2019, In : Journal of Polymer Science, Part A: Polymer Chemistry. 57, 18, p. 1982–1993 12 p.

Research output: Contribution to journal › Article › Research › peer-review

23 Citations (Scopus)

Development of flexible supercapacitors using an inexpensive graphene/PEDOT/MnO2 sponge composite

Moussa, M., Shi, G., Wu, H., Zhao, Z., Voelcker, N. H., Losic, D. & Ma, J., 5 Jul 2017, In : Materials & Design. 125, p. 1-10 10 p.

Research output: Contribution to journal › Article › Research › peer-review

10 Citations (Scopus)

Development of HPLC and LC–MS/MS methods for the analysis of ivacaftor, its major metabolites and lumacaftor in plasma and sputum of cystic fibrosis patients treated with ORKAMBI or KALYDECO

Schneider, E. K., Reyes Ortega, F., Wilson, J. W., Kotsimbos, T., Keating, D., Li, J. & Velkov, T., 1 Dec 2016, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1038, p. 57-62 6 p.

Research output: Contribution to journal › Article › Research › peer-review

6 Citations (Scopus)

Deviation from the unimolecular micelle paradigm of PAMAM dendrimers induced by strong interligand interactions

Wang, B., Geitner, N. K., Davis, T. P., Ke, P. C., Ladner, D. A. & Ding, F., 2015, In : Journal of Physical Chemistry C. 119, 33, p. 19475-19484 10 p.

Research output: Contribution to journal › Article › Research › peer-review

72 Citations (Scopus)

Dextran-based doxorubicin nanocarriers with improved tumor penetration

Sagnella, S. M., Duong, H. T. T., Macmillan, A., Boyer, C., Whan, R. M., McCarroll, J. A., Davis, T. P. & Kavallaris, M., 2014, In : Biomacromolecules. 15, 1, p. 262 - 275 14 p.

Research output: Contribution to journal › Article › Research › peer-review

3 Citations (Scopus)

Diazepam binding in the plasma of parturient women

Ridd, M. J., Brown, K. F. & Nation, R. L., 1 Jan 1980, In : Australian Journal of Pharmaceutical Sciences. 9, 2, 1 p.

Research output: Contribution to journal › Article › Research › peer-review

15 Citations (Scopus)

Diazepam plasma binding in the perinatal period: Influence of nonesterified fatty acids

Ridd, M. J., Brown, K. F., Moore, R. G., McBride, W. G. & Nation, R. L., 1 Mar 1982, In : European Journal of Clinical Pharmacology. 22, 2, p. 153-160 8 p.

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Dietary docosahexaenoic acid supplementation enhances expression of fatty acid-binding protein 5 at the blood–brain barrier and brain docosahexaenoic acid levels

Pan, Y., Morris, E. R., Scanlon, M. J., Marriott, P. J., Porter, C. J. H. & Nicolazzo, J. A., 1 Jul 2018, In : Journal of Neurochemistry. 146, 2, p. 186-197 12 p.

Research output: Contribution to journal › Article › Research › peer-review

44 Citations (Scopus)

Differences in colloidal structure of PEGylated nanomaterials dictate the likelihood of accelerated blood clearance

Kaminskas, L., McLeod, V., Porter, C. & Boyd, B., 2011, In : Journal of Pharmaceutical Sciences. 11, p. 5069 - 5077 9 p.

Research output: Contribution to journal › Article › Research › peer-review

5 Citations (Scopus)

Differences in pre- and post-prandial plasma lipid profiles affect the extraction efficiency of a model highly lipophilic drug from beagle dog plasma

Porter, C. J. H., Caliph, S. M. & Charman, W. N., 1997, In : Journal of Pharmaceutical and Biomedical Analysis. p. 175 - 180 6 p.

Research output: Contribution to journal › Article › Research › peer-review

1 Citation (Scopus)

Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli

Bergen, P. J., Bulitta, J. B., Sime, F. B., Lipman, J., McGregor, M. J., Millen, N., Paterson, D. L., Kirkpatrick, C. M. J., Roberts, J. A. & Landersdorfer, C. B., 1 May 2018, In : Diagnostic Microbiology and Infectious Disease. 91, 1, p. 69-76 8 p.

Research output: Contribution to journal › Article › Research › peer-review

16 Citations (Scopus)

Differences in the lipoprotein binding profile of halofantrine in fed and fasted human or beagle plasma are dictated by the respective masses of core apolar lipoprotein lipid

McIntosh, M. P., Porter, C. J. H., Wasan, K. M., Ramaswamy, M. & Charman, W. N., 1999, In : Journal of Pharmaceutical Sciences. 88, 3, p. 378 - 384 7 p.

Research output: Contribution to journal › Article › Research › peer-review

22 Citations (Scopus)

Differences in the lipoprotein distribution of halfantrine are regulated by lippoprotein apolar lipid and protein concentration and lipid transfer protein I activity: In vitro studies in normolipidemic and dyslipidemic human plasmas

Wasan, K. M., Ramaswamy, M., McIntosh, M. P., Porter, C. J. H. & Charman, W. N., 1999, In : Journal of Pharmaceutical Sciences. 88, 2, p. 185 - 190 6 p.

Research output: Contribution to journal › Article › Research › peer-review