Research Output 1975 2019

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2017
3 Citations (Scopus)

Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid

Clulow, A. J., Parrow, A., Hawley, A., Khan, J., Pham, A. C., Larsson, P., Bergström, C. A. S. & Boyd, B. J., 7 Dec 2017, In : Journal of Physical Chemistry B. 121, 48, p. 10869-10881 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Characterization of the Polymyxin D Synthetase Biosynthetic Cluster and Product Profile of Paenibacillus polymyxa ATCC 10401

Galea, C. A., Han, M., Zhu, Y., Roberts, K., Wang, J., Thompson, P. E., Li, J. & Velkov, T., 26 May 2017, In : Journal of Natural Products. 80, 5, p. 1264-1274 11 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Characterizing the time-course of antihypertensive activity and optimal dose range of fimasartan via mechanism-based population modeling

Bulitta, J. B., Paik, S. H., Chi, Y. H., Kim, T. H., Shin, S., Landersdorfer, C. B., Jiao, Y., Yadav, R. & Shin, B. S., 30 Sep 2017, In : European Journal of Pharmaceutical Sciences. 107, p. 32-44 13 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Cofibrillization of Pathogenic and Functional Amyloid Proteins with Gold Nanoparticles against Amyloidogenesis

Javed, I., Sun, Y., Adamcik, J., Wang, B., Kakinen, A., Pilkington, E. H., Ding, F., Mezzenga, R., Davis, T. P. & Ke, P. C., 11 Dec 2017, In : Biomacromolecules. 18, 12, p. 4316-4322 7 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Comb poly(oligo(2-ethyl-2-oxazoline)methacrylate)-peptide conjugates prepared by aqueous Cu(0)-mediated polymerization and reductive amination

Collins, J., Wallis, S. J., Simula, A., Whittaker, M. R., McIntosh, M. P., Wilson, P., Davis, T. P., Haddleton, D. M. & Kempe, K., 1 Jan 2017, In : Macromolecular Rapid Communications. 38, 2, 7 p., 1600534.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Comparison across Three Hybrid Lipid-Based Drug Delivery Systems for Improving the Oral Absorption of the Poorly Water-Soluble Weak Base Cinnarizine

Joyce, P., Yasmin, R., Bhatt, A., Boyd, B. J., Pham, A. & Prestidge, C. A., 6 Nov 2017, In : Molecular Pharmaceutics. 14, 11, p. 4008-4018 11 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Complex multiblock bottle-brush architectures by RAFT polymerization

Kerr, A., Hartlieb, M., Sanchis, J., Smith, T. & Perrier, S., 2017, In : Chemical Communications. 53, 87, p. 11901-11904 4 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids

Birru, W. A., Warren, D., Headey, S. J., Benameur, H., Porter, C., Pouton, C. W. & Chalmers, D. K., 6 Mar 2017, In : Molecular Pharmaceutics. 14, 3, p. 566-579 14 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)
7 Citations (Scopus)

Computational Models of the Intestinal Environment. 3. The Impact of Cholesterol Content and pH on Mixed Micelle Colloids

Suys, E. J. A., Warren, D. B., Porter, C. J. H., Benameur, H., Pouton, C. W. & Chalmers, D. K., 6 Nov 2017, In : Molecular Pharmaceutics. 14, 11, p. 3684-3697 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Copolyampholytes Produced from RAFT Polymerization of Protic Ionic Liquids

Fouillet, C. C. J., Greaves, T. L., Quinn, J. F., Davis, T. P., Adamcik, J., Sani, M. A., Separovic, F., Drummond, C. J. & Mezzenga, R., 28 Nov 2017, In : Macromolecules. 50, 22, p. 8965-8978 14 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Correlating in Vitro Solubilization and Supersaturation Profiles with in Vivo Exposure for Lipid Based Formulations of the CETP Inhibitor CP-532,623

McEvoy, C. L., Trevaskis, N. L., Feeney, O. M., Edwards, G. A., Perlman, M. E., Ambler, C. M. & Porter, C. J. H., 4 Dec 2017, In : Molecular Pharmaceutics. 14, 12, p. 4525-4538 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Design and evaluation of novel polymyxin fluorescent probes

Yun, B., Roberts, K. D., Thompson, P. E., Nation, R. L., Velkov, T. & Li, J., 11 Nov 2017, In : Sensors. 17, 11, 8 p., 2598.

Research output: Contribution to journalArticleResearchpeer-review

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8 Citations (Scopus)

Development of a Gemcitabine-Polymer Conjugate with Prolonged Cytotoxicity against a Pancreatic Cancer Cell Line

Joubert, F., Martin, L., Perrier, S. & Pasparakis, G., 16 May 2017, In : ACS Macro Letters. 6, 5, p. 535-540 6 p.

Research output: Contribution to journalArticleResearchpeer-review

25 Citations (Scopus)

Development of flexible supercapacitors using an inexpensive graphene/PEDOT/MnO2 sponge composite

Moussa, M., Shi, G., Wu, H., Zhao, Z., Voelcker, N. H., Losic, D. & Ma, J., 5 Jul 2017, In : Materials & Design. 125, p. 1-10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Differential effects of silver and iron oxide nanoparticles on IAPP amyloid aggregation

Wang, M., Kakinen, A., Pilkington, E. H., Davis, T. P. & Ke, P-C., 1 Mar 2017, In : Biomaterials Science. 5, 3, p. 485-493 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

DNA-based probes for flow cytometry analysis of endocytosis and recycling

Dumont, C. F. M., Czuba, E., Chen, M., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., 1 Apr 2017, In : Traffic. 18, 4, p. 242-249 8 p.

Research output: Contribution to journalArticleResearchpeer-review

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72 Citations (Scopus)

Dosing guidance for intravenous colistin in critically ill patients

Nation, R. L., Garonzik, S. M., Thamlikitkul, V., Giamarellos-Bourboulis, E. J., Forrest, A., Paterson, D. L., Li, J. & Silveira, F. P., 2017, In : Clinical Infectious Diseases. 64, 5, p. 565-571 7 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Dual-action cancer therapy with targeted porous silicon nanovectors

Cifuentes Rius, A., Ivask, A., Sporleder, E., Kaur, I., Assan, Y., Rao, S., Warther, D., Prestidge, C. A., Durand, J-O. & Voelcker, N., 4 Aug 2017, In : Small. 13, 29, 6 p., 1701201.

Research output: Contribution to journalArticleResearchpeer-review

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4 Citations (Scopus)

Dynamic formation of nanostructured particles from vesicles via invertase hydrolysis for on-demand delivery

Fong, W-K., Sánchez-Ferrer, A., Ortelli, F. G., Sun, W., Boyd, B. J. & Mezzenga, R., 2017, In : RSC Advances. 7, 8, p. 4368-4377 10 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers

Haque, S., McLeod, V. M., Jones, S., Fung, S., Whittaker, M., McIntosh, M., Pouton, C., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Oct 2017, In : European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 408-418 11 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Effects of protein corona on IAPP amyloid aggregation, fibril remodelling, and cytotoxicity

Pilkington, E. H., Xing, Y., Wang, B., Kakinen, A., Wang, M., Davis, T. P., Ding, F. & Ke, P-C., 1 Dec 2017, In : Scientific Reports. 7, 1, 13 p., 2455.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Efficiently specified ventral midbrain dopamine neurons from human pluripotent stem cells under Xeno-free conditions restore motor deficits in Parkinsonian rodents

Niclis, J. C., Gantner, C. W., Alsanie, W. F., McDougall, S. J., Bye, C. R., Elefanty, A. G., Stanley, E. G., Haynes, J. M., Pouton, C. W., Thompson, L. H. & Parish, C. L., 1 Mar 2017, In : Stem Cells Translational Medicine. 6, 3, p. 937-948 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

Electrochemical fingerprints of brominated trihaloacetic acids (HAA3) mixtures in water

Cetó, X., Saint, C., Chow, C. W. K., Voelcker, N. H. & Prieto-Simón, B., 2017, In : Sensors and Actuators B: Chemical. 247, p. 70-77 8 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

To, E. E., Vlahos, R., Luong, R., Halls, M. L., Reading, P. C., King, P. T., Chan, C., Drummond, G. R., Sobey, C. G., Broughton, B. R. S., Starkey, M. R., van der Sluis, R., Lewin, S. R., Bozinovski, S., O'Neill, L. A. J., Quach, T., Porter, C. J. H., Brooks, D. A., O'Leary, J. & Selemidis, S., 1 Dec 2017, In : Nature Communications. 8, 1, 17 p., 69.

Research output: Contribution to journalArticleResearchpeer-review

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38 Citations (Scopus)

Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

Yarwood, R. E., Imlach, W. L., Lieu, T., Veldhuis, N. A., Jensen, D. D., Herenbrink, C. K., Aurelio, L., Cai, Z., Christie, M. J., Poole, D. P., Porter, C. J. H., McLean, P., Hicks, G. A., Geppetti, P., Halls, M. L., Canals, M. & Bunnett, N. W., 14 Nov 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 46, p. 12309-12314 6 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Engineered hydrogen-bonded glycopolymer capsules and their interactions with antigen presenting cells

Kempe, K., Xiang, S. D., Wilson, P., Rahim, M. A., Ju, Y., Whittaker, M. R., Haddleton, D. M., Plebanski, M., Caruso, F. & Davis, T. P., 22 Feb 2017, In : ACS Applied Materials and Interfaces. 9, 7, p. 6444-6452 9 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Evolution of Microphase Separation with Variations of Segments of Sequence-Controlled Multiblock Copolymers

Zhang, J., Deubler, R., Hartlieb, M., Martin, L., Tanaka, J., Patyukova, E., Topham, P. D., Schacher, F. H. & Perrier, S., 26 Sep 2017, In : Macromolecules. 50, 18, p. 7380-7387 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Extending the Excitation Wavelength of Potential Photosensitizers via Appendage of a Kinetically Stable Terbium(III) Macrocyclic Complex for Applications in Photodynamic Therapy

Ung, P., Clerc, M., Huang, H., Qiu, K., Chao, H., Seitz, M., Boyd, B. J., Graham, B. & Gasser, G., 17 Jul 2017, In : Inorganic Chemistry. 56, 14, p. 7960-7974 15 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

From Breast Cancer to Antimicrobial: Combating Extremely Resistant Gram-Negative "superbugs" Using Novel Combinations of Polymyxin B with Selective Estrogen Receptor Modulators

Hussein, M. H., Schneider, E. K., Elliott, A. G., Han, M., Reyes-Ortega, F., Morris, F., Blastovich, M. A. T., Jasim, R., Currie, B. J., Mayo, M., Baker, M., Cooper, M. A., Li, J. & Velkov, T., 1 Jul 2017, In : Microbial Drug Resistance. 23, 5, p. 640-650 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

Alzahrani, K. J. H., Ali, J. A. M., Eze, A. A., Looi, W. L., Tagoe, D. N. A., Creek, D. J., Barrett, M. P. & De Koning, H. P., 1 Aug 2017, In : International Journal for Parasitology: Drugs and Drug Resistance. 7, 2, p. 206-226 21 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Functional characterization of the unique terminal thioesterase domain from polymyxin synthetase

Galea, C., Roberts, K. D., Zhu, Y., Thompson, P. E., Li, J. & Velkov, T., 31 Jan 2017, In : Biochemistry. 56, 4, p. 657-668 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Functional multisite copolymer by one-pot sequential RAFT copolymerization of styrene and maleic anhydride

Moriceau, G., Gody, G., Hartlieb, M., Winn, J., Kim, H., Mastrangelo, A., Smith, T. & Perrier, S., 28 Jul 2017, In : Polymer Chemistry. 8, 28, p. 4152-4161 10 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Garlic-inspired trisulfide linkers for thiol-stimulated H2S release

Ercole, F., Whittaker, M. R., Halls, M. L., Boyd, B. J., Davis, T. P. & Quinn, J. F., 2017, In : Chemical Communications. 53, 57, p. 8030-8033 4 p.

Research output: Contribution to journalArticleResearchpeer-review

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2 Citations (Scopus)

Gelofusine ameliorates colistin-induced nephrotoxicity

Sivanesan, S. S., Azad, M. A. K., Schneider, E. K., Ahmed, M. U., Huang, J., Wang, J., Li, J., Nation, R. L. & Velkov, T., 1 Dec 2017, In : Antimicrobial Agents and Chemotherapy. 61, 12, 7 p., e00985.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia

Murray, G. L., Tsyganov, K., Kostoulias, X. P., Bulach, D. M., Powell, D., Creek, D. J., Boyce, J. D., Paulsen, I. T. & Peleg, A. Y., 15 Feb 2017, In : Journal of Infectious Diseases. 215, 1, p. S52-S57

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Gold-decorated porous silicon nanopillars for targeted hyperthermal treatment of bacterial infections

Alhmoud, H., Cifuentes-Rius, A., Delalat, B. & Voelcker, N. H., 1 Jan 2017, In : ACS Applied Materials and Interfaces. 9, 39, p. 33707-33716 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation

Cifuentes-Rius, A., Ivask, A., Das, S., Pena Auladell, N., Fabregas, L., Fletcher, N., Houston, Z., Thurecht, K. J. & Voelcker, N. H., 29 Nov 2017, In : ACS Applied Materials and Interfaces. 9, 47, p. 41159-41167 9 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Graphene as a photothermal actuator for control of lipid mesophase structure

Quinn, M. D. J., Wang, T., Du, J. D., Boyd, B. J., Hawley, A. & Notley, S. M., 7 Jan 2017, In : Nanoscale. 9, 1, p. 341-348 8 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

High-dose ampicillin-sulbactam combinations combat polymyxin-resistant Acinetobacter baumannii in a hollow-fiber infection model

Lenhard, J. R., Smith, N. M., Bulman, Z. P., Tao, X., Thamlikitkul, V., Shin, B. S., Nation, R. L., Li, J., Bulitta, J. B. & Tsuji, B. T., 1 Mar 2017, In : Antimicrobial Agents and Chemotherapy. 61, 3, 6 p., e01268.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

High-intensity meropenem combinations with polymyxin B: new strategies to overcome carbapenem resistance in Acinetobacter baumannii

Lenhard, J. R., Bulitta, J. B., Connell, T. D., King-Lyons, N., Landersdorfer, C., Cheah, S-E., Thamlikitkul, V., Shin, B. S., Rao, G., Holden, P. N., Walsh, T. J., Forrest, A., Nation, R. L., Li, J. & Tsuji, B. T., 2017, In : Journal of Antimicrobial Chemotherapy. 72, 1, p. 153-165 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

High Tg poly(ester amide)s by melt polycondensation of monomers from renewable resources; citric acid, D-glucono-δ-lactone and amino acids: A DSC study

de Jongh, P. A. J. M., Paul, P. K. C., Khoshdel, E., Wilson, P., Kempe, K. & Haddleton, D. M., 1 Sep 2017, In : European Polymer Journal. 94, p. 11-19 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

High throughput, quantitative analysis of human osteoclast differentiation and activity

Diepenhorst, N., Nowell, C., Rueda, P., Henriksen, K., Pierce, T., Cook, A., Pastoureau, P., Sabatini, M., Charman, W., Christopoulos, A., Summers, R., Sexton, P. & Langmead, C., 15 Feb 2017, In : Analytical Biochemistry. 519, p. 51-56 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Hydrolyzable Poly[Poly(Ethylene Glycol) Methyl Ether Acrylate]-Colistin Prodrugs through Copper-Mediated Photoinduced Living Radical Polymerization

Zhu, C., Schneider, E. K., Nikolaou, V., Klein, T., Li, J., Davis, T. P., Whittaker, M. R., Wilson, P., Kempe, K., Velkov, T. & Haddleton, D. M., 19 Jul 2017, In : Bioconjugate Chemistry. 28, 7, p. 1916-1924 9 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Inclusion of digestible surfactants in solid SMEDDS formulation removes lag time and influences the formation of structured particles during digestion

Vithani, K., Hawley, A., Jannin, V., Pouton, C. & Boyd, B. J., 1 May 2017, In : The AAPS Journal. 19, 3, p. 754-764 11 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Influence of Size and Shape on the Biodistribution of Nanoparticles Prepared by Polymerization-Induced Self-Assembly

Kaga, S., Truong, N. P., Esser, L., Senyschyn, D., Sanyal, A., Sanyal, R., Quinn, J. F., Davis, T. P., Kaminskas, L. M. & Whittaker, M. R., 11 Dec 2017, In : Biomacromolecules. 18, 12, p. 3963-3970 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Instrumental Analytical Techniques for the Characterization of Crystals in Pharmaceutics and Foods

Qiao, Y., Qiao, R., He, Y., Shi, C., Liu, Y., Hao, H., Su, J. & Zhong, J., 1 Nov 2017, In : Crystal Growth and Design. 17, 11, p. 6138-6148 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes

Han, M. L., Shen, H. H., Hansford, K. A., Schneider, E. K., Sivanesan, S., Roberts, K. D., Thompson, P. E., Le Brun, A. P., Zhu, Y., Sani, M-A., Separovic, F., Blaskovich, M. A. T., Baker, M. A., Moskowitz, S. M., Cooper, M. A., Li, J. & Velkov, T., 11 Aug 2017, In : ACS Infectious Diseases. 3, 8, p. 606-619 14 p.

Research output: Contribution to journalArticleResearchpeer-review