Research Output 1975 2019

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2003
13 Citations (Scopus)

Tumoral drug metabolism: perspectives and therapeutic implications

Doherty, M. M. & Michael, M., 2003, In : Current Drug Metabolism. 4, 2, p. 131 - 149 19 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)
2004
46 Citations (Scopus)

Active and intelligent inhaler device development

Tobyn, M., Staniforth, J. N., Morton, D. A. V., Harmer, Q. & Newton, M. E., 2004, In : International Journal of Pharmaceutics. 277, 1-2, p. 31 - 37 7 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

A novel cubic phase of medium chain lipid origin for the delivery of poorly water soluble drugs

Kossena, G. A., Charman, W. N., Boyd, B. J. & Porter, C. J. H., 2004, In : Journal of Controlled Release. 99, 2, p. 217 - 229 13 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol

Nicolazzo, J. A., Reed, B. L. & Finnin, B. C., 2004, In : Journal of Pharmaceutical Sciences. 93, 2, p. 431 - 440 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Degradation of berenil (diminazene aceturate) in acidic aqueous solution

Campbell, M., Prankerd, R. J., Davie, A. S. & Charman, W. N., 2004, In : Journal of Pharmacy and Pharmacology. 56, 10, p. 1327 - 1332 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Development and application of a micro-capillary rheometer for in-vitro evaluation of parenteral injectability

Allahham, A., Mainwaring, D. E., Stewart, P. J. & Marriott, J. L., 2004, In : Journal of Pharmacy and Pharmacology. 56, 6, p. 709 - 716 8 p.

Research output: Contribution to journalArticleResearchpeer-review

148 Citations (Scopus)

Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations

Kaukonen, A. M., Boyd, B. J., Porter, C. J. H. & Charman, W. N., 2004, In : Pharmaceutical Research. 21, 2, p. 245 - 253 9 p.

Research output: Contribution to journalArticleResearchpeer-review

93 Citations (Scopus)

Drug solubilization behaviour during in vitro digestion of suspension formulations of poorly water-soluble drugs in triglyceride lipids

Kaukonen, A. M., Boyd, B. J., Charman, W. N. & Porter, C. J. H., 2004, In : Pharmaceutical Research. 21, 2, p. 254 - 260 7 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures

Islam, M. N., Stewart, P. J., Larson, I. C. & Hartley, P., 2004, In : Journal of Pharmaceutical Sciences. 93, 4, p. 1030 - 1038 9 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
10 Citations (Scopus)

Flow and injection characteristics of pharmaceutical parenteral formulations using a micro-capillary rheometer

Allahham, A., Stewart, P. J., Marriott, J. L. & Mainwaring, D. E., 2004, In : International Journal of Pharmaceutics. 270, 1-2, p. 139 - 148 10 p.

Research output: Contribution to journalArticleResearchpeer-review

516 Citations (Scopus)

Identification of an antimalarial synthetic trioxolane drug development candidate

Vennerstrom, J. L., Arbe-Barnes, S., Brun, R., Charman, S. A., Chiu, F. C. K., Chollet, J., Dong, Y., Dorn, A., Hunziker, D., Matile, H., McIntosh, K. A., Padmanilayam, M., Santo Tomas, J., Scheurer, C., Scorneaux, B., Tang, Y., Urwyler, H., Wittlin, S. & Charman, W. N., 19 Aug 2004, In : Nature. 430, 7002, p. 900-904 5 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

In vitro and in vivo evaluation of a sulfobutyl ether beta-cyclodextrin enabled etomidate formulation

McIntosh, M. P., Schwarting, N. & Rajewski, R. A., 2004, In : Journal of Pharmaceutical Sciences. 93, 10, p. 2585 - 2594 10 p.

Research output: Contribution to journalArticleResearchpeer-review

93 Citations (Scopus)

Lactose surface modification by decantation: are drug-fine lactose ratios the key to better dispersion of slametereol xinafoate from lactose-intercative mixtures?

Islam, M. N., Stewart, P. J., Larson, I. C. & Hartley, P., 2004, In : Pharmaceutical Research. 21, 3, p. 492 - 499 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Modeling the deagglomeration of micronised benzodiazepines from powder mixtures added to dissolution media

Zhao, F-Y. & Stewart, P. J., 2004, In : Journal of Pharmaceutical Sciences. 93, 6, p. 1618 - 1627 10 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Modification of buccal drug delivery following pretreatment with skin penetration enhancers

Nicolazzo, J. A., Reed, B. L. & Finnin, B. C., 2004, In : Journal of Pharmaceutical Sciences. 93, 8, p. 2054 - 2063 10 p.

Research output: Contribution to journalArticleResearchpeer-review

71 Citations (Scopus)

New manzamine alkaloids from an Indo-Pacific sponge. Pharmacokinetics, oral availability, and the significant activity of several manzamines against HIV-I, AIDS opportunistic infections, and inflammatory diseases

Yousaf, M., Hammond, N. L., Peng, J., Wahyuono, S., McIntosh, K. A., Charman, W. N., Mayer, A. M. S. & Hamann, M. T., 2004, In : Journal of Medicinal Chemistry. 47, 14, p. 3512 - 3517 6 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin

Grellepois, F., Chorki, F., Ourevitch, M., Charneau, S., Grellier, P., McIntosh, K. A., Charman, W. N., Pradines, B., Crousse, B., Bonnet-Delpon, D. & Begue, J-P., 2004, In : Journal of Medicinal Chemistry. 47, 6, p. 1423 - 1433 11 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Pharmacokinetics of recombinant human leukemia inhibitory factor in sheep

Segrave, A. M., Mager, D. E., Charman, S. A., Edwards, G. & Porter, C. J. H., Jun 2004, In : Journal of Pharmacology and Experimental Therapeutics. 309, 3, p. 1085-1092 8 p.

Research output: Contribution to journalArticleResearchpeer-review

106 Citations (Scopus)

Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: a phase diagram approach

Kossena, G. A., Charman, W. N., Boyd, B. J., Dunstan, D. E. & Porter, C. J. H., 2004, In : Journal of Pharmaceutical Sciences. 93, 2, p. 332 - 348 17 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Simple method for the assay of linezolid in Brain Heart Infusion broth by high-performance liquid chromatography

Li, J., Rayner, C. R., Dixson, S. D. & Nation, R. L., 2004, In : Biomedical Chromatography. 18, 1, p. 1 - 5 5 p.

Research output: Contribution to journalArticleResearchpeer-review

205 Citations (Scopus)

Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation

Porter, C. J. H., Kaukonen, A. M., Boyd, B. J., Edwards, G. A. & Charman, W. N., 2004, In : Pharmaceutical Research. 21, 8, p. 1405 - 1412 8 p.

Research output: Contribution to journalArticleResearchpeer-review

138 Citations (Scopus)

The cohesive-adhesive balances in dry powder inhaler formulations I: Direct quantification by atomic force microscopy

Begat, P., Morton, D. A. V., Staniforth, J. N. & Price, R., 2004, In : Pharmaceutical Research. 21, 9, p. 1591 - 1597 7 p.

Research output: Contribution to journalArticleResearchpeer-review

88 Citations (Scopus)

The Cohesive-Adhesive Balances in Dry Powder Inhaler Formulations II: Influence on Fine Particle Delivery Characteristics

Begat, P., Morton, D. A. V., Staniforth, J. N. & Price, R., 2004, In : Pharmaceutical Research. 21, 10, p. 1826 - 1833 8 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

The interaction of the penetration enhancer DDAIP with a phospholipid model membrane

Wolka, A. M., Rytting, J. H., Reed, B. L. & Finnin, B. C., 2004, In : International Journal of Pharmaceutics. 271, 1-Feb, p. 5 - 10 6 p.

Research output: Contribution to journalArticleResearchpeer-review

185 Citations (Scopus)

The transdermal revolution

Thomas, B. J. & Finnin, B. C., 2004, In : Drug Discovery Today. 9, 16, p. 697 - 703 7 p.

Research output: Contribution to journalArticleResearchpeer-review

164 Citations (Scopus)

Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: studies with halofantrine

Porter, C. J. H., Kaukonen, A. M., Taillardat-Bertschinger, A., Boyd, B. J., O'Connor, J. M., Edwards, G. A. & Charman, W. N., 2004, In : Journal of Pharmaceutical Sciences. 93, 5, p. 1110 - 1121 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2005
12 Citations (Scopus)

An improved method for the purification of rat liver-type fatty acid binding protein from Escherichia coli

Velkov, T., Chuang, S., Prankerd, R. J., Sakellaris, H. H., Porter, C. J. H. & Scanlon, M. J., 2005, In : Protein Expression and Purification. 44, 1, p. 23 - 31 9 p.

Research output: Contribution to journalArticleResearchpeer-review

121 Citations (Scopus)

Atomic force microscopy and direct surface force measurements (IUPAC technical report)

Ralston, J., Larson, I. C., Rutland, M. W., Feiler, A. A. & Kleijn, M., 2005, In : Pure and Applied Chemistry. 77, 12, p. 2149 - 2170 22 p.

Research output: Contribution to journalArticleResearchpeer-review

36 Citations (Scopus)

Bile increases intestinal lymphatic drug transport in the fasted rat

Trevaskis, N., Porter, C. J. H. & Charman, W. N., 2005, In : Pharmaceutical Research. 22, 11, p. 1863 - 1870 8 p.

Research output: Contribution to journalArticleResearchpeer-review

131 Citations (Scopus)

Buccal Penetration Enhancers - How Do They Really Work?

Nicolazzo, J., Reed, B. L. & Finnin, B. C., 2005, In : Journal of Controlled Release. 105, 18, p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Colloidal Drug Delivery

Boyd, B. J., 2005, In : Drug Delivery Report Autumn/Winter 2005. 15, p. 63 - 70 8 p.

Research output: Contribution to journalArticleOther

13 Citations (Scopus)

Enhanced buccal mucosal retention and reduced buccal permeabiltiy of estradiol in the presence of padimate O and Azone(R): A mechanistic study

Nicolazzo, J., Reed, B. L. & Finnin, B. C., 2005, In : Journal of Pharmaceutical Sciences. 94, 4, p. 873 - 882 10 p.

Research output: Contribution to journalArticleResearchpeer-review

38 Citations (Scopus)

Enhancing the buccal mucosal uptake and retention of triamcinolone acetonide

Nicolazzo, J. A., Reed, B. L. & Finnin, B. C., 2005, In : Journal of Controlled Release. 105, 3, p. 240 - 248 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Factors affecting shear thickening behavior of a concentrated injectable suspension of levodopa

Allahham, A., Stewart, P. J., Marriott, J. L. & Mainwaring, D. E., 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2393 - 2402 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Formulation of poorly water-soluble drugs for oral administration

Pouton, C. W., 2005, In : Bull. Tech. Gattefosse. 98, p. 39-51 13 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Human bioavailability of propranolol from a matrix-in-cylinder system with a HPMC-Gelucire(R) core

Mehuys, E., Remon, J. P., Korst, A., Van Bortel, L., Mols, R., Augustijns, P., Porter, C. J. H. & Vervaet, C., 2005, In : Journal of Controlled Release. 107, p. 523 - 536 14 p.

Research output: Contribution to journalArticleResearchpeer-review

79 Citations (Scopus)

Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug

Kossena, G. A., Charman, W. N., Boyd, B. J. & Porter, C. J. H., 2005, In : Journal of Pharmaceutical Sciences. 94, 3, p. 481 - 492 12 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Inter- and intralaboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasi-standardized methods and materials

Chilcott, R. P., Barai, N., Beezer, A. E., Brain, S. I., Brown, M. B., Bunge, A. L., Burgess, S. E., Cross, S., Dalton, C. H., Dias, M., Farinha, A., Finnin, B. C., Gallgher, S. J., Green, D. M., Gunt, H., Gwyther, R. L., Heard, C. M., Jarvis, C. A., Kamiyama, F., Kasting, G. B. & 22 others, Ley, E. E., Lim, S. T., Mcnaughton, G. S., Morris, A., Nazemi, M. H., Pellet, M. A., Du Plessis, J., Quan, Y. S., Raghavan, S. L., Roberts, M., Romonchuk, W., Roper, C. S., Schenk, D., Simonsen, L., Simpson, A., Traversa, B. D., Trottet, L., Watkinson, A., Wilkinson, S. C., Williams, F. M., Yamamoto, A. & Hadgraft, J., 2005, In : Journal of Pharmaceutical Sciences. 94, 3, p. 632 - 638 7 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Kinetics of iron-mediated artemisinin degradation: effect of solvent composition and iron salt

Creek, D. J., Chiu, F. C. K., Prankerd, R. J., Charman, S. A. & Charman, W. N., 2005, In : Journal of Pharmaceutical Sciences. 94, 8, p. 1820 - 1829 10 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Lymphatic absorption is the primary contributor to the systemic availability of epoetin alfa following subcutaneous administration to sheep

McLennan, D. N., Porter, C. J. H., Edwards, G. A., Martin, S. W., Heatherington, A. C. & Charman, S. A., 2005, In : Journal of Pharmacology and Experimental Therapeutics. 313, 1, p. 345 - 351 7 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Measurement of lactose crystallinity using Raman spectroscopy

Murphy, B. M., Prescott, S. W. & Larson, I. C., 2005, In : Journal of Pharmaceutical and Biomedical Analysis. 38, 1, p. 186 - 190 5 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

Mechanisms of action of novel skin penetration enhancers: phospholipid versus skin lipid liposomes

El Maghraby, G. M. M., Campbell, M. & Finnin, B. C., 2005, In : International Journal of Pharmaceutics. 305, 1-Feb, p. 90 - 104 15 p.

Research output: Contribution to journalArticleResearchpeer-review

74 Citations (Scopus)

Morphology and gelation of thermosensitive chitosan hydrogels

Crompton, K. E., Prankerd, R. J., Paganin, D. M., Scott, T. F., Horne, M. K., Finkelstein, D. I., Gross, K. A. & Forsythe, J. S., 2005, In : Biophysical Chemistry. 117, 1, p. 47 - 53 7 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes

Dong, Y., Chollet, J., Matile, H., Charman, S. A., Chiu, F. C. K., Charman, W. N., Scorneaux, B., Urwyler, H., Santo Tomas, J., Scheurer, C., Snyder, C., Dorn, A., Wang, X., Karle, J. M., Tang, Y., Wittlin, S., Brun, R. & Vennerstrom, J. L., 2005, In : Journal of Medicinal Chemistry. 48, 15, p. 4953 - 4961 9 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

Subcutaneous drug delivery and the role of the lymphatics

McLennan, D. N., Porter, C. J. H. & Charman, S. A., 2005, In : Drug Discovery Today: Technologies. 2, 1, p. 89-96 8 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Submicron dispersions of hexosomes based on novel glycerate surfactants

Fong, C., Krodkiewska, I., Wells, D., Boyd, B. J., Booth, J., Bhargava, S., McDowall, A. & Hartley, P. G., 2005, In : Australian Journal of Chemistry. 58, 9, p. 683 - 687 5 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Surface roughness contribution to the adhesion force distribution of salmeterol xinafoate on lactose carriers by atomic force microscopy

Islam, M. N., Stewart, P. J., Larson, I. C. & Hartley, P., 2005, In : Journal of Pharmaceutical Sciences. 94, 7, p. 1500 - 1511 12 p.

Research output: Contribution to journalArticleResearchpeer-review