Research Output 1975 2019

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2017

Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

Marsh, A. P. L., Heron, D., Edwards, T. J., Quartier, A., Galea, C., Nava, C., Rastetter, A., Moutard, M. L., Anderson, V., Bitoun, P., Bunt, J., Faudet, A., Garel, C., Gillies, G., Gobius, I., Guegan, J., Heide, S., Keren, B., Lesne, F., Lukic, V. & 33 othersMandelstam, S. A., McGillivray, G., McIlroy, A., Méneret, A., Mignot, C., Morcom, L. R., Odent, S., Paolino, A., Pope, K., Riant, F., Robinson, G. A., Spencer-Smith, M., Srour, M., Stephenson, S. E. M., Tankard, R., Trouillard, O., Welniarz, Q., Wood, A., Brice, A., Rouleau, G., Attié-Bitach, T., Delatycki, M. B., Mandel, J. L., Amor, D. J., Roze, E., Piton, A., Bahlo, M., Billette De Villemeur, T., Sherr, E. H., Leventer, R. J., Richards, L. J., Lockhart, P. J. & Depienne, C., Apr 2017, In : Nature Genetics. 49, 4, p. 511-514 4 p.

Research output: Contribution to journalArticleResearchpeer-review

NanoEHS beyond toxicity-focusing on biocorona

Lin, S., Mortimer, M., Chen, R., Kakinen, A., Riviere, J. E., Davis, T. P., Ding, F. & Ke, P-C., 2017, In : Environmental Science: Nano. 4, 7, p. 1433-1454 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanotopography mediated osteogenic differentiation of human dental pulp derived stem cells

Bachhuka, A., Delalat, B., Ghaemi, S. R., Gronthos, S., Voelcker, N. H. & Vasilev, K., 7 Oct 2017, In : Nanoscale. 9, 37, p. 14248-14258 11 p.

Research output: Contribution to journalArticleResearchpeer-review

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Nephrotoxicity of polymyxins: is there any difference between colistimethate and polymyxin B?

Zavascki, A. P. & Nation, R. L., 1 Mar 2017, In : Antimicrobial Agents and Chemotherapy. 61, 3, 10 p., e02319-16.

Research output: Contribution to journalArticleResearchpeer-review

Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief

Jensen, D. D., Lieu, T., Halls, M. L., Veldhuis, N. A., Imlach, W. L., Mai, Q. N., Poole, D. P., Quach, T., Aurelio, L., Conner, J., Klein Herenbrink, C., Barlow, N., Simpson, J. S., Scanlon, M. J., Graham, B., McCluskey, A., Robinson, P. J., Escriou, V., Nassini, R., Materazzi, S. & 6 othersGeppetti, P., Hicks, G. A., Christie, M. J., Porter, C. J. H., Canals, M. & Bunnett, N. W., 31 May 2017, In : Science Translational Medicine. 9, 392, 15 p., aal3447.

Research output: Contribution to journalArticleResearchpeer-review

Neurovascular Alterations in Alzheimer’s Disease: Transporter Expression Profiles and CNS Drug Access

McInerney, M. P., Short, J. L. & Nicolazzo, J. A., 1 Jul 2017, In : The AAPS Journal. 19, 4, p. 940-956 17 p.

Research output: Contribution to journalArticleResearchpeer-review

New polymyxin B dosing strategies to fortify old allies in the war against KPC-2-producing Klebsiella pneumoniae

Bulman, Z. P., Satlin, M. J., Chen, L., Kreiswirth, B. N., Shin, B. S., Walsh, T. J., Holden, P. N., Forrest, A., Nation, R. L., Li, J. & Tsuji, B., 1 Apr 2017, In : Antimicrobial Agents and Chemotherapy. 61, 4, 9 p., e02023-16.

Research output: Contribution to journalArticleResearchpeer-review

Nitric oxide-sensing actuators for modulating structure in lipid-based liquid crystalline drug delivery systems

Liu, Q., Hu, J., Whittaker, M. R., Davis, T. P. & Boyd, B. J., 15 Dec 2017, In : Journal of Colloid and Interface Science. 508, p. 517-524 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Novel Gd-Loaded Silicon Nanohybrid: A Potential Epidermal Growth Factor Receptor Expressing Cancer Cell Targeting Magnetic Resonance Imaging Contrast Agent

Sinha, S., Tong, W. Y., Williamson, N. H., McInnes, S. J. P., Puttick, S., Cifuentes-Rius, A., Bhardwaj, R., Plush, S. E. & Voelcker, N. H., 13 Dec 2017, In : ACS Applied Materials and Interfaces. 9, 49, p. 42601-42611 11 p.

Research output: Contribution to journalArticleResearchpeer-review

On-demand Antimicrobial Treatment with Antibiotic-Loaded Porous Silicon Capped with a pH-Responsive Dual Plasma Polymer Barrier

Vasani, R. B., Szili, E. J., Rajeev, G. & Voelcker, N. H., 4 Jul 2017, In : Chemistry - An Asian Journal. 12, 13, p. 1605-1614 10 p.

Research output: Contribution to journalArticleResearchpeer-review

One-Pot Synthesis of ABCDE Multiblock Copolymers with Hydrophobic, Hydrophilic, and Semi-Fluorinated Segments

Anastasaki, A., Oschmann, B., Willenbacher, J., Melker, A., Van Son, M. H. C., Truong, N. P., Schulze, M. W., Discekici, E. H., McGrath, A. J., Davis, T. P., Bates, C. M. & Hawker, C. J., 13 Nov 2017, In : Angewandte Chemie - International Edition. 56, 46, p. 14483-14487 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Optimisation of selective laser melting parameters for the Ni-based superalloy IN-738 LC using Doehlert's design

Perevoshchikova, N., Rigaud, J., Sha, Y., Heilmaier, M., Finnin, B., Labelle, E. & Wu, X., 2017, In : Rapid Prototyping Journal. 23, 5, p. 881-892 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Optimized HPLC-MS method for the high-throughput analysis of clinical samples of ivacaftor, its major metabolites, and lumacaftor in biological fluids of cystic fibrosis patients

Schneider, E. K., Reyes-Ortega, F., Li, J. & Velkov, T., 15 Oct 2017, In : Journal of Visualized Experiments. 2017, 128, e56084.

Research output: Contribution to journalArticleResearchpeer-review

Oral Mucosal Epithelial Cells Grown on Porous Silicon Membrane for Transfer to the Rat Eye

Irani, Y. D., Klebe, S., Mcinnes, S. J. P., Jasieniak, M., Voelcker, N. H. & Williams, K. A., 1 Dec 2017, In : Scientific Reports. 7, 1, 11 p., 10042.

Research output: Contribution to journalArticleResearchpeer-review

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Oxygen-Releasing Coatings for Improved Tissue Preservation

Forget, A., Staehly, C., Ninan, N., Harding, F. J., Vasilev, K., Voelcker, N. H. & Blencowe, A., 9 Oct 2017, In : ACS Biomaterials Science and Engineering. 3, 10, p. 2384-2390 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Parallel and antiparallel cyclic d/l peptide nanotubes

Silk, M. R., Newman, J., Ratcliffe, J. C., White, J. F., Caradoc-Davies, T., Price, J. R., Perrier, S., Thompson, P. E. & Chalmers, D. K., 2017, In : Chemical Communications. 53, 49, p. 6613-6616 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacodynamics of colistin and fosfomycin: A 'treasure trove' combination combats KPC-producing Klebsiella pneumoniae

Zhao, M., Bulman, Z. P., Lenhard, J. R., Satlin, M. J., Kreiswirth, B. N., Walsh, T. J., Marrocco, A., Bergen, P. J., Nation, R. L., Li, J., Zhang, J. & Tsuji, B., 1 Jul 2017, In : Journal of Antimicrobial Chemotherapy. 72, 7, p. 1985-1990 6 p., dkx070.

Research output: Contribution to journalArticleResearchpeer-review

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Pharmacodynamics of dose-escalated ‘front-loading’ polymyxin B regimens against polymyxin-resistant mcr-1-harbouring Escherichia coli

Smith, N. M., Bulman, Z. P., Sieron, A. O., Bulitta, J. B., Holden, P. N., Nation, R. L., Li, J., Wright, G. D. & Tsuji, B., 1 Aug 2017, In : Journal of Antimicrobial Chemotherapy. 72, 8, p. 2297-2303 7 p., dkx121.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetic/toxicodynamic analysis of colistin-associated acute kidney injury in critically Ill patients

Forrest, A., Garonzik, S. M., Thamlikitkul, V., Giamarellos-Bourboulis, E. J., Paterson, D. L., Li, J., Silveira, F. P. & Nation, R. L., 1 Nov 2017, In : Antimicrobial Agents and Chemotherapy. 61, 11, 5 p., e01367.

Research output: Contribution to journalArticleResearchpeer-review

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Pharmacokinetics/pharmacodynamics of pulmonary delivery of colistin against Pseudomonas aeruginosa in a mouse lung infection model

Lin, Y. W., Zhou, Q. T., Cheah, S-E., Zhao, J., Chen, K., Wang, J., Chan, H-K. & Li, J., 1 Mar 2017, In : Antimicrobial Agents and Chemotherapy. 61, 3, 11 p., e02025-16.

Research output: Contribution to journalArticleResearchpeer-review

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Pharmacokinetics and relative bioavailability of an oral amoxicillin-apramycin combination in pigs

Dai, C., Zhao, T., Yang, X., Xiao, X., Velkov, T. & Tang, S., 1 Apr 2017, In : PLoS ONE. 12, 4, 12 p., e0176149.

Research output: Contribution to journalArticleResearchpeer-review

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Pharmacokinetics of the individual major components of polymyxin B and colistin in rats

Sivanesan, S., Roberts, K., Wang, J., Cheah, S-E., Thompson, P. E., Li, J., Nation, R. & Velkov, T., 27 Jan 2017, In : Journal of Natural Products. 80, 1, p. 225-229 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmakokinetik und Pharmakodynamik von Antibiotika in der Intensivmedizin

Sorgel, F., Höhl, R., Glaser, R., Stelzer, C., Munz, M., Vormittag, M., Kinzig, M., Bulitta, J., Landersdorfer, C., Junger, A., Christ, M., Wilhelm, M. & Holzgrabe, U., Feb 2017, In : Medizinische Klinik - Intensivmedizin und Notfallmedizin. 112, 1, p. 11-22 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Photo-Switchable Self-Assemblies Based on Thymine-Containing Bolaamphiphiles

Al-Shereiqi, A. S., Boyd, B. J. & Saito, K., 4 Jul 2017, In : ChemPlusChem. 82, p. 1135-1144 10 p.

Research output: Contribution to journalArticleResearchpeer-review

pH-Responsive, Amphiphilic Core-Shell Supramolecular Polymer Brushes from Cyclic Peptide-Polymer Conjugates

Larnaudie, S. C., Brendel, J. C., Jolliffe, K. A. & Perrier, S., 19 Dec 2017, In : ACS Macro Letters. 6, 12, p. 1347-1351 5 p.

Research output: Contribution to journalArticleResearchpeer-review

pH-Responsive Transferrin-pHlexi particles capable of targeting cells in vitro

Wong, A. S. M., Czuba, E., Chen, M. Z., Yuen, D., Cupic, K. I., Yang, S., Hodgetts, R. Y., Selby, L. I., Johnston, A. P. R. & Such, G. K., 2017, In : ACS Macro Letters. 6, 3, p. 315-320 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin

Schneider, E. K., Huang, J. X., Carbone, V., Han, M., Zhu, Y., Nang, S., Khoo, K. K., Mak, J., Cooper, M. A., Li, J. & Velkov, T., 1 Feb 2017, In : ACS Infectious Diseases. 3, 3, p. 249-258 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasma Proteome Association and Catalytic Activity of Stealth Polymer-Grafted Iron Oxide Nanoparticles

Wang, M., Siddiqui, G., Gustafsson, O. J. R., Käkinen, A., Javed, I., Voelcker, N. H., Creek, D. J., Ke, P. C. & Davis, T. P., 27 Sep 2017, In : Small. 13, 36, 1701528.

Research output: Contribution to journalArticleResearchpeer-review

Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate

Counihan, N. A., Chisholm, S. A., Bullen, H. E., Srivastava, A., Sanders, P. R., Jonsdottir, T. K., Weiss, G. E., Ghosh, S., Crabb, B. S., Creek, D. J., Gilson, P. R. & De Koning-Ward, T. F., 2 Mar 2017, In : eLife. 6, 31 p., e23217.

Research output: Contribution to journalArticleResearchpeer-review

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Poly(2-oxazoline)-based micro- and nanoparticles: a review

Wilson, P., Ke, P. C., Davis, T. P. & Kempe, K., 1 Mar 2017, In : European Polymer Journal. 88, p. 486-515 30 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymerization induced self-assembly: tuning of morphology using ionic strength and pH

Zhou, D., Dong, S., Kuchel, R. P., Perrier, S. & Zetterlund, P. B., 28 May 2017, In : Polymer Chemistry. 8, 20, p. 3082-3089 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymers with acyl-protected perthiol chain termini as convenient building blocks for doubly responsive H2S-donating nanoparticles

Yu, S. H., Ercole, F., Veldhuis, N. A., Whittaker, M. R., Davis, T. P. & Quinn, J. F., 7 Nov 2017, In : Polymer Chemistry. 8, 41, p. 6362-6367 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymyxin B in combination with meropenem against carbapenemase-producing Klebsiella pneumoniae: pharmacodynamics and morphological changes

Sharma, R., Patel, S., Abboud, C., Diep, J., Ly, N. S., Pogue, J. M., Kaye, K. S., Li, J. & Rao, G. G., 1 Feb 2017, In : International Journal of Antimicrobial Agents. 49, 2, p. 224-232 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymyxin combinations combat Escherichia coli harboring mcr-1 and blaNDM-5: Preparation for a postantibiotic Era

Bulman, Z. P., Chen, L., Walsh, T. J., Satlin, M. J., Qian, Y., Bulitta, J. B., Peloquin, C. A., Holden, P. N., Nation, R. L., Li, J., Kreiswirth, B. N. & Tsuji, B. T., 1 Jul 2017, In : mBio. 8, 4, 10 p., e00540-17.

Research output: Contribution to journalArticleResearchpeer-review

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Polymyxin-resistant, carbapenem-resistant Acinetobacter baumannii is eradicated by a triple combination of agents that lack individual activity

Lenhard, J. R., Thamlikitkul, V., Silveira, F. P., Garonzik, S. M., Tao, X., Forrest, A., Shin, B. S., Kaye, K. S., Bulitta, J. B., Nation, R., Li, J. & Tsuji, B., 2017, In : Journal of Antimicrobial Chemotherapy. 72, 5, p. 1415-1420 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Porous conducting polymer prepared through liquid crystal template for drug delivery

Uppalapati, D., Boyd, B., Travas-Sejdic, J. & Svirskis, D., 2017, In : International Journal of Nanotechnology. 14, 1-6, p. 422-431 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Potential toxicity of polymyxins in human lung epithelial cells

Ahmed, M. U., Velkov, T., Lin, Y-W., Yun, B., Nowell, C. J., Zhou, F., Zhou, Q. T., Chan, K., Azad, M. A. K. & Li, J., 1 Jun 2017, In : Antimicrobial Agents and Chemotherapy. 61, 6, 12 p., e02690-16.

Research output: Contribution to journalArticleResearchpeer-review

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Practical chain-end reduction of polymers obtained with ATRP

Gutekunst, W. R., Anastasaki, A., Lunn, D. J., Truong, N. P., Whitfield, R., Jones, G. R., Treat, N. J., Abdilla, A., Barton, B. E., Clark, P. G., Haddleton, D. M., Davis, T. P. & Hawker, C. J., Sep 2017, In : Macromolecular Chemistry and Physics. 218, 18, 7 p., 1700107.

Research output: Contribution to journalArticleResearchpeer-review

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Precise control of drug loading and release of an NSAID-polymer conjugate for long term osteoarthritis intra-articular drug delivery

Sulistio, A., Reyes-Ortega, F., D'Souza, A. M., Ng, S. M. Y., Valade, D., Quinn, J. F., Donohue, A. C., Mansfeld, F., Blencowe, A., Qiao, G., Prankerd, R., Quirk, S., Whittaker, M. R., Davis, T. P. & Tait, R. J., 1 Jan 2017, In : Journal of Materials Chemistry B. 5, 31, p. 6221-6226 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Prevention of postpartum haemorrhage by community-based auxiliary midwives in hard-to-reach areas of Myanmar: A qualitative inquiry into acceptability and feasibility of task shifting

Than, K. K., Mohamed, Y., Oliver, V., Myint, T., La, T., Beeson, J. G. & Luchters, S., 17 May 2017, In : BMC Pregnancy and Childbirth. 17, 1, 10 p., 146.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Probing Endosomal Escape Using pHlexi Nanoparticles

Kongkatigumjorn, N., Cortez-Jugo, C., Czuba, E., Wong, A. S. M., Hodgetts, R. Y., Johnston, A. P. R. & Such, G. K., 1 Apr 2017, In : Macromolecular Bioscience. 17, 4, 11 p., 1600248.

Research output: Contribution to journalArticleResearchpeer-review

Probing the Dynamic Nature of Self-Assembling Cyclic Peptide-Polymer Nanotubes in Solution and in Mammalian Cells

Rho, J. Y., Brendel, J. C., Macfarlane, L. R., Mansfield, E. D. H., Peltier, R., Rogers, S., Hartlieb, M. & Perrier, S., 2017, (Accepted/In press) In : Advanced Functional Materials. 11 p., 1704569.

Research output: Contribution to journalArticleResearchpeer-review

Pulmonary Pharmacokinetics of colistin following administration of dry powder aerosols in rats

Lin, Y. W., Zhou, Q. T., Hu, Y., Onufrak, N. J., Sun, S., Wang, J., Forrest, A., Chan, H. K. & Li, J., 1 Nov 2017, In : Antimicrobial Agents and Chemotherapy. 61, 11, 12 p., e00973.

Research output: Contribution to journalArticleResearchpeer-review

Pulsed-voltage atom probe tomography of low conductivity and insulator materials by application of ultrathin metallic coating on nanoscale specimen geometry

Adineh, V. R., Marceau, R. K. W., Chen, Y., Si, K. J., Velkov, T., Cheng, W., Li, J. & Fu, J., 1 Oct 2017, In : Ultramicroscopy. 181, p. 150-159 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Purification and characterization of adenovirus core protein VII: A histone-like protein that is critical for adenovirus core formation

Sharma, G., Moria, N., Williams, M., Krishnarjuna, B. & Pouton, C. W., 1 Jul 2017, In : Journal of General Virology. 98, 7, p. 1785-1794 10 p., 000817.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Rapid detection of nicotine from breath using desorption ionisation on porous silicon

Guinan, T. M., Abdelmaksoud, H. & Voelcker, N. H., 2017, In : Chemical Communications. 53, 37, p. 5224-5226 3 p.

Research output: Contribution to journalArticleResearchpeer-review