Research Output 1975 2019

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2001
72 Citations (Scopus)

Animal models for the study of intestinal lymphatic drug transport

Edwards, G. A., Porter, C. J. H., Caliph, S. M., Khoo, S-M. & Charman, W. N., 2001, In : Advanced Drug Delivery Reviews. 50, p. 45 - 60 16 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

A simple and efficient high-performance liquid chromatographic assay for etomidate in plasma

McIntosh, M. P. & Rajewski, R. A., 2001, In : Journal of Pharmaceutical and Biomedical Analysis. 24, 4, p. 689 - 694 6 p.

Research output: Contribution to journalArticleResearchpeer-review

113 Citations (Scopus)
80 Citations (Scopus)

Characterisation of adhesional properties of lactose carriers using atomic force microscopy

Louey, M. D., Mulvaney, P. & Stewart, P. J., 2001, In : Journal of Pharmaceutical and Biomedical Analysis. 25, p. 559 - 567 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Core molecular orbital contribution to N 2 O isomerization as studied using theoretical electron momentum spectroscopy

Wang, F., Larkins, F. P., Brunger, M. J., Michalewicz, M. T. & Winkler, D. A., 2001, In : Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy. 57, 1, p. 9-15 7 p.

Research output: Contribution to journalArticleResearchpeer-review

239 Citations (Scopus)

Intestinal lymphatic drug transport: an update

Porter, C. J. H. & Charman, W. N., 2001, In : Advanced Drug Delivery Reviews. 50, p. 61 - 80 20 p.

Research output: Contribution to journalArticleResearchpeer-review

290 Citations (Scopus)

In vitro assessment of oral lipid based formulations

Porter, C. J. H. & Charman, W. N., 2001, In : Advanced Drug Delivery Reviews. 50, p. 127 - 147 20 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)
45 Citations (Scopus)

Lymphatic absorption is a significant contributor to the subcutaneous bioavailability of insulin in a sheep model

Charman, S. A., McLennan, D. N., Edwards, G. & Porter, C. J. H., 2001, In : Pharmaceutical Research. 18, 11, p. 1620-1626 7 p.

Research output: Contribution to journalArticleResearchpeer-review

78 Citations (Scopus)

Lymphatic transport of proteins after s.c. injection: Implications of animal model selection

Porter, C. J. H., Edwards, G. & Charman, S. A., 23 Aug 2001, In : Advanced Drug Delivery Reviews. 50, 1-2, p. 157-171 15 p.

Research output: Contribution to journalArticleResearchpeer-review

75 Citations (Scopus)

Neonatal hepatic drug elimination

Gow, P. J., Ghabrial, H., Smallwood, R. A., Morgan, D. J. & Ching, M. S., 2001, In : Pharmacology and Toxicology. 88, p. 3 - 15 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Onset of cohesive behaviour in gas fluidized beds: a numerical study using DEM simulation

Rhodes, M. J., Wang, X. S. S., Nguyen, M., Stewart, P. J. & Liffman, K., 2001, In : Chemical Engineering Science. 56, 14, p. 4433 - 4438 6 p.

Research output: Contribution to journalArticleResearchpeer-review

76 Citations (Scopus)

Phase I and pharmacokinetic study of photodynamic therapy for high-grade gliomas using a novel boronated porphyrin

Rosenthal, M. A., Kavar, B., Hill, J. S., Morgan, D. J., Nation, R. L., Stylli, S. S., Basser, R. L., Uren, S., Geldard, H., Green, M. D., Kahl, S. B. & Kaye, A. H., 2001, In : Journal of Clinical Oncology. 19, 2, p. 519 - 524 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymeric materials for advanced drug delivery: Adv Drug Deliv Rev

Pouton, C. W., 2001, In : Advanced Drug Delivery Reviews. 53, p. 1-3 3 p.

Research output: Contribution to journalArticleResearchpeer-review

127 Citations (Scopus)

Study of mixing in gas-fluidized beds using a DEM model

Rhodes, M. J., Wang, X. S., Nguyen, M., Stewart, P. J. & Liffman, K., 2001, In : Chemical Engineering Science. 56, 8, p. 2859 - 2866 8 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

The impact of P-glycoprotein efflux on enterocyte residence time and enterocyte-based metabolism of verapamil

Johnson, B. M., Charman, W. N. & Porter, C. J. H., 2001, In : Journal of Pharmacy and Pharmacology. 53, 12, p. 1611 - 1619 9 p.

Research output: Contribution to journalArticleResearchpeer-review

113 Citations (Scopus)

Use of discrete element method simulation in studying fluidization characteristics: influence of interparticle force

Rhodes, M. J., Wang, S. S., Nguyen, M., Stewart, P. J. & Liffman, K., 2001, In : Chemical Engineering Science. 56, 1, p. 69 - 76 8 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

A physicochemical basis for the extensive intestinal lymphatic transport of a poorly lipid soluble antimalarial, halofantrine hydrochloride, after postprandial administration to dogs

Khoo, S. M., Prankerd, R. J., Edwards, G. A., Porter, C. J. H. & Charman, W. N., 2002, In : Journal of Pharmaceutical Sciences. 91, 3, p. 647 - 659 13 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

Crushing or altering medications: What's happen residential aged -care faciiities?

Paradiso, L. M., Roughead, E. E., Gilbert, A. L., Cosh, D., Nation, R. L., Barnes, L., Cheek, J. & Batlaniyne, A., 1 Sep 2002, In : Australasian Journal on Ageing. 21, 3, p. 123-127 5 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Effect of dietary fatty acids on the intestinal permeability of marker drug compounds in excised rat jejunum

Vine, D. F., Charman, S. A., Gibson, P. R., Sinclair, A. J. & Porter, C. J. H., 2002, In : Journal of Pharmacy and Pharmacology. 54, 6, p. 809 - 819 11 p.

Research output: Contribution to journalArticleResearchpeer-review

207 Citations (Scopus)

Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products

Sek, L., Porter, C. J. H., Kaukonen, A. M. & Charman, W. N., 2002, In : Journal of Pharmacy and Pharmacology. 54, 1, p. 29 - 41 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Kupffer cell phagocytosis and malaria. Hepatic kupffer cell phagocytic function in rats with erythrocytic-stage malaria

Nobes, M. S., Ghabrial, H., Simms, K. M., Smallwood, R. A., Morgan, D. J. & Sewell, R. B., 2002, In : Journal of Gastroenterology and Hepatology. 17, 5, p. 598 - 605 8 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Lipophilicity and other parameters affecting brain penetration

Atkinson, F., Cole, S., Laverty, C. E. & van de Waterbeemd, H., 2002, In : Current Medicinal Chemistry - Central Nervous System Agents. 2, 12, p. 229 - 240 12 p.

Research output: Contribution to journalArticleOther

134 Citations (Scopus)

Particle interactions involved in aerosol dispersion of ternary interactive mixtures

Louey, M. & Stewart, P. J., 2002, In : Pharmaceutical Research. 19, 10, p. 1524 - 1531 8 p.

Research output: Contribution to journalArticleResearchpeer-review

72 Citations (Scopus)

Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates

Avery, M. A., Alvim-Gaston, M., Vroman, J. A., Wu, B., Ager, A., Peters, W., Robinson, B. L. & Charman, W. N., 2002, In : Journal of Medicinal Chemistry. 45, 19, p. 4321 - 4335 15 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats

Holm, R., Porter, C. J. H., Mullertz, A., Kristensen, H. G. & Charman, W. N., 2002, In : Pharmaceutical Research. 19, 9, p. 1354 - 1361 8 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The influence of aggregate microenvironment on the dissolution of oxazepam in ternary surfactant interactive mixtures

Stewart, P. J. & Liu, J., 2002, In : Journal of Pharmacy and Pharmacology. 54, 9, p. 1181 - 1187 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2003
68 Citations (Scopus)

A kinetic evaluation of the absorption, efflux, and metabolism of verapamil in the autoperfused rat jejunum

Johnson, B. M., Chen, W., Borchardt, R. T., Charman, W. N. & Porter, C. J. H., 2003, In : Journal of Pharmacology and Experimental Therapeutics. 305, 1, p. 151 - 158 8 p.

Research output: Contribution to journalArticleResearchpeer-review

An electron momentum spectroscopy and density functional theory study of the outer valence electronic structure of stella-2, 6-dione

Nixon, KL., Wang, F., Campbell, L., Maddern, T., Winkler, D., Gleiter, R., Loeb, P., Weigold, E. & Brunger, M. J., 2003, In : Journal of Physics B: Atomic, Molecular and Optical Physics. 36, 14, p. 3155-3171 17 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

A novel method for determining hepatic sinusoidal oxygen permeability in the isolated perfused rat liver using [15O]O2

Froomes, P. R. A., Sachinidis, J., Ghabrial, H., Tochon-Danguy, H., Scott, A. M., Ching, M. S., Morgan, D. J. & Angus, P. W., 2003, In : Nuclear Medicine and Biology. 30, p. 93 - 100 8 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)
183 Citations (Scopus)

Characterisation of drug release from cubosomes using the pressure ultrafiltration method

Boyd, B. J., 2003, In : International Journal of Pharmaceutics. 260, 2, p. 239 - 247 9 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)
7 Citations (Scopus)

De-agglomeration of micronized benzodiazepines in dissolution media measured by laser diffraction particle sizing

Zhao, F-Y. & Stewart, P. J., 2003, In : Journal of Pharmacy and Pharmacology. 55, 6, p. 749 - 755 7 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Desbutylhalofantrine: evaluation of QT prolongation and other cardiovascular effects after intravenous administration in vivo

McIntosh, M. P., Batey, A. J., Porter, C. J. H., Charman, W. N. & Coker, S. J., 2003, In : Journal of Cardiovascular Pharmacology. 41, 3, p. 406 - 413 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)
117 Citations (Scopus)

Exploring the electronic structure of 2, 6-stelladione from momentum space I: the p-dominant molecular orbitals in the outer valence shell

Wang, F., Brunger, M. J., McCarthy, I. E. & Winkler, D. A., 2003, In : Chemical Physics Letters. 382, 3, p. 217-225 9 p.

Research output: Contribution to journalArticleResearchpeer-review

93 Citations (Scopus)

Influence of the physico-chemical carrier properties on the in vitro aerosol deposition from interactive mixtures

Louey, M. D., Razia, S. & Stewart, P. J., 2003, In : International Journal of Pharmaceutics. 252, p. 87 - 98 12 p.

Research output: Contribution to journalArticleResearchpeer-review

102 Citations (Scopus)

Intestinal lymphatic transport of halofantrine occurs after oral administration of a unit-dose lipid-based formulation to fasted dogs

Khoo, S-M., Shackleford, D. M., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 2003, In : Pharmaceutical Research. 20, 9, p. 1460 - 1465 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigating the patient who has hepatitis B

Wong, M-L. & Gibson, P. R., 2003, In : Medicine Today. 4, 5, p. 72 - 82 11 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Partitioning of halofantrine hydrochloride between water, micellar solutions, and soybean oil: effects on its apparent ionization constant

Taillardat-Bertschinger, A., Perry, C. S., Galland, A., Prankerd, R. J. & Charman, W. N., 2003, In : Journal of Pharmaceutical Sciences. 92, 11, p. 2217 - 2228 12 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Pharmacokinetic model to describe the lymphatic absorption of r-metHu-Leptin after subcutaneous injection to sheep

McLennan, D. N., Porter, C. J. H., Edwards, G. A., Brumm, M., Martin, S. W. & Charman, S. A., 1 Aug 2003, In : Pharmaceutical Research. 20, 8, p. 1156-1162 7 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Self-micellization of gemfibrozil 1-0- acyl glucuronide in aqueous solution

Shackleford, D. M., Prankerd, R. J., Scanlon, M. J. & Charman, W. N., 2003, In : Pharmaceutical Research. 20, 3, p. 465 - 470 6 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

The effects of phytoestrogenic isoflavones on the formation and disposition of paracetamol sulfate in the isolated perfused rat liver

Lucas, A. N., Nation, R. L., Milne, R. W., Reynolds, G. D. & Evans, A. M., 1 May 2003, In : Journal of Pharmacy and Pharmacology. 55, 5, p. 639-646 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

The effects of the phytoestrogenic isoflavone genistein on the hepatic disposition of preformed and hepatically generated gemfibrozil 1-0-acyl glucuronide in the isolated perfused rat liver

Lucas, A. N., Brogan, L. R., Nation, R. L., Milne, R. W., Evans, A. M. & Shackleford, D. M., 2003, In : Journal of Pharmacy and Pharmacology. 55, p. 1433 - 1439 7 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

The effects of various in vitro conditions on the permeability characteristics of the buccal mucosa

Nicolazzo, J., Reed, B. L. & Finnin, B. C., 2003, In : Journal of Pharmaceutical Sciences. 92, 12, p. 2399 - 2410 12 p.

Research output: Contribution to journalArticleResearchpeer-review