Research Output 1975 2019

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2018
6 Citations (Scopus)

Sonication-enabled rapid production of stable liquid metal nanoparticles grafted with poly(1-octadecene-: Alt -maleic anhydride) in aqueous solutions

Lin, Y., Genzer, J., Li, W., Qiao, R., Dickey, M. D. & Tang, S. Y., 14 Nov 2018, In : Nanoscale. 10, 42, p. 19871-19878 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Spontaneous zwitterionic copolymerisation: An undervalued and efficacious technique for the synthesis of functional degradable oligomers and polymers

de Jongh, P. A. J. M., Haddleton, D. M. & Kempe, K., 2018, In : Progress in Polymer Science. 87, p. 228-246 19 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation

von Halling Laier, C., Gibson, B., van de Weert, M., Boyd, B. J., Rades, T., Boisen, A., Hook, S. & Nielsen, L. H., 25 Oct 2018, In : International Journal of Pharmaceutics. 550, 1-2, p. 35-44 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Sputum Active Polymyxin Lipopeptides: Activity against Cystic Fibrosis Pseudomonas aeruginosa Isolates and Their Interactions with Sputum Biomolecules

Schneider-Futschik, E. K., Paulin, O. K. A., Hoyer, D., Roberts, K. D., Ziogas, J., Baker, M. A., Karas, J., Li, J. & Velkov, T., 11 May 2018, In : ACS Infectious Diseases. 4, 5, p. 646-655 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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6 Citations (Scopus)

Stable White Light-Emitting Biocomposite Films

Gotta, J., Shalom, T. B., Aslanoglou, S., Cifuentes-Rius, A., Voelcker, N. H., Elnathan, R., Shoseyov, O. & Richter, S., 13 Jun 2018, In : Advanced Functional Materials. 28, 24, 9 p., 1706967.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria

Velkov, T., Gallardo-Godoy, A., Swarbrick, J. D., Blaskovich, M. A. T., Elliott, A. G., Han, M., Thompson, P. E., Roberts, K. D., Huang, J. X., Becker, B., Butler, M. S., Lash, L. H., Henriques, S. T., Nation, R. L., Sivanesan, S., Sani, M. A., Separovic, F., Mertens, H., Bulach, D., Seemann, T. & 3 others, Owen, J., Li, J. & Cooper, M. A., 19 Apr 2018, In : Cell Chemical Biology. 25, 4, p. 380-391 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Structured Multi-Stakeholder Workshops to Advance a Global Transformative Roadmap for Pharmaceutical Workforce

Bruno, A. F., Bader, L., Bates, I., Brock, T., Galbraith, K. J., Anderson, C., Larson, I. C., Paulino, E., Rouse, M., Tofade, T., Boone, J., Carrasqueira, J., James, S. & Whitley, Y., 3 Nov 2018, In : Innovations in Pharmacy. 9, 3, 9 p., 13.

Research output: Contribution to journalArticleResearchpeer-review

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2 Citations (Scopus)
1 Citation (Scopus)

Synergistic killing of polymyxin B in combination with the antineoplastic drug mitotane against polymyxin-susceptible and -resistant Acinetobacter baumannii: A metabolomic study

Tran, T. B., Bergen, P. J., Creek, D. J., Velkov, T. & Li, J., 16 Apr 2018, In : Frontiers in Pharmacology. 9, 14 p., 359.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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8 Citations (Scopus)

Synthesis, aggregation and responsivity of block copolymers containing organic arsenicals

Tanaka, J., Tani, S., Peltier, R., Pilkington, E. H., Kerr, A., Davis, T. P. & Wilson, P., 7 Apr 2018, In : Polymer Chemistry. 9, 13, p. 1551-1556 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Synthesis and Pharmacological Evaluation of Noscapine-Inspired 5-Substituted Tetrahydroisoquinolines as Cytotoxic Agents

Devine, S. M., Yong, C., Amenuvegbe, D., Aurelio, L., Muthiah, D., Pouton, C., Callaghan, R., Capuano, B. & Scammells, P. J., 27 Sep 2018, In : Journal of Medicinal Chemistry. 61, 18, p. 8444-8456 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Synthesis of Sub-100 nm Glycosylated Nanoparticles via a One Step, Free Radical, and Surfactant Free Emulsion Polymerization

Lunn, A. M. & Perrier, S., 2018, In : Macromolecular Rapid Communications. 39, 19, 5 p., 1800122.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Systematic study of the structural parameters affecting the self-assembly of cyclic peptide-poly(ethylene glycol) conjugates

Mansfield, E. D. H., Hartlieb, M., Catrouillet, S., Rho, J. Y., Larnaudie, S. C., Rogers, S. E., Sanchis, J., Brendel, J. C. & Perrier, S., 1 Jan 2018, In : Soft Matter. 14, 30, p. 6320-6326 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The Applications of 3D Printing in Pulmonary Drug Delivery and Treatment of Respiratory Disorders

Haque, S., Md, S., Whittaker, M. & Kaminskas, L. M., 1 Jan 2018, In : Current Pharmaceutical Design. 24, 42, p. 5072-5080 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

The Curious Case of the OZ439 Mesylate Salt: An Amphiphilic Antimalarial Drug with Diverse Solution and Solid State Structures

Clulow, A. J., Salim, M., Hawley, A., Gilbert, E. P. & Boyd, B. J., 7 May 2018, In : Molecular Pharmaceutics. 15, 5, p. 2027-2035 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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7 Citations (Scopus)

The Essential Elements of a Risk Governance Framework for Current and Future Nanotechnologies

Stone, V., Führ, M., Feindt, P. H., Bouwmeester, H., Linkov, I., Sabella, S., Murphy, F., Bizer, K., Tran, L., Ågerstrand, M., Fito, C., Andersen, T., Anderson, D., Bergamaschi, E., Cherrie, J. W., Cowan, S., Dalemcourt, J. F., Faure, M., Gabbert, S., Gajewicz, A. & 17 others, Fernandes, T. F., Hristozov, D., Johnston, H. J., Lansdown, T. C., Linder, S., Marvin, H. J. P., Mullins, M., Purnhagen, K., Puzyn, T., Sanchez Jimenez, A., Scott-Fordsmand, J. J., Streftaris, G., van Tongeren, M., Voelcker, N. H., Voyiatzis, G., Yannopoulos, S. N. & Poortvliet, P. M., 1 Jul 2018, In : Risk Analysis. 38, 7, p. 1321-1331 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The flavonoid, 2′-methoxy-6-methylflavone, affords neuroprotection following focal cerebral ischaemia

Clarkson, A. N., Boothman-Burrell, L., Dósa, Z., Nagaraja, R. Y., Jin, L., Parker, K., van Nieuwenhuijzen, P. S., Neumann, S., Gowing, E. K., Gavande, N., Ahring, P. K., Holm, M. M., Hanrahan, J. R., Nicolazzo, J. A., Jensen, K. & Chebib, M., 29 Jan 2018, In : Journal of Cerebral Blood Flow and Metabolism. 39, 7, p. 1266-1282 17 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

The impact of digestion is essential to the understanding of milk as a drug delivery system for poorly water soluble drugs

Boyd, B. J., Salim, M., Clulow, A. J., Ramirez, G., Pham, A. C. & Hawley, A., 28 Dec 2018, In : Journal of Controlled Release. 292, p. 13-17 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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5 Citations (Scopus)

The inhibitory effects of eighteen front-line antibiotics on the substrate uptake mediated by human Organic anion/cation transporters, Organic anion transporting polypeptides and Oligopeptide transporters in in vitro models

Lu, X., Chan, T., Zhu, L., Bao, X., Velkov, T., Zhou, Q. T., Li, J., Chan, H. K. & Zhou, F., 30 Mar 2018, In : European Journal of Pharmaceutical Sciences. 115, p. 132-143 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites

Schneider, E. K., McQuade, R. M., Carbone, V. C., Reyes-Ortega, F., Wilson, J. W., Button, B., Saito, A., Poole, D. P., Hoyer, D. & Li, J., 1 Jan 2018, In : ERJ Open Research. 4, 1, 10 p., 00127-2017.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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13 Citations (Scopus)

The role of algal organic matter in the separation of algae and cyanobacteria using the novel “Posi” - Dissolved air flotation process

Rao, N. R. H., Yap, R., Whittaker, M., Stuetz, R. M., Jefferson, B., Peirson, W. L., Granville, A. M. & Henderson, R. K., 1 Mar 2018, In : Water Research. 130, p. 20-30 11 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Transformation of Biopharmaceutical Classification System Class I and III Drugs Into Ionic Liquids and Lipophilic Salts for Enhanced Developability Using Lipid Formulations

Williams, H. D., Ford, L., Lim, S., Han, S., Baumann, J., Sullivan, H., Vodak, D., Igonin, A., Benameur, H., Pouton, C. W., Scammells, P. J. & Porter, C. J. H., 2018, In : Journal of Pharmaceutical Sciences. 107, 1, p. 203–216 14 p.

Research output: Contribution to journalArticleResearchpeer-review

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Tristearin as a Model Cuticle for High-Throughput Screening of Agricultural Adjuvant Systems

Webster, G. R., Bisset, N. B., Cahill, D. M., Jones, P., Killick, A., Hawley, A. & Boyd, B. J., 5 Dec 2018, In : ACS Omega. 3, 12, p. 16672-16680 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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2 Citations (Scopus)

Tumor targeting with pH-responsive poly(2-oxazoline)-based nanogels for metronomic doxorubicin treatment

Hoelzer, D., Leiske, M. N., Hartlieb, M., Bus, T., Pretzel, D., Hoeppener, S., Kempe, K., Thierbach, R. & Schubert, U. S., 27 Apr 2018, In : Oncotarget. 9, 32, p. 22316-22331 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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6 Citations (Scopus)

Tunable 2D binary colloidal alloys for soft nanotemplating

Fernández-Rodríguez, M. Á., Elnathan, R., Ditcovski, R., Grillo, F., Conley, G. M., Timpu, F., Rauh, A., Geisel, K., Ellenbogen, T., Grange, R., Scheffold, F., Karg, M., Richtering, W., Voelcker, N. H. & Isa, L., 21 Dec 2018, In : Nanoscale. 10, 47, p. 22189-22195 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Understanding Effects of PAMAM Dendrimer Size and Surface Chemistry on Serum Protein Binding with Discrete Molecular Dynamics Simulations

Wang, B., Sun, Y., Davis, T. P., Ke, P. C., Wu, Y. & Ding, F., 4 Sep 2018, In : ACS Sustainable Chemistry & Engineering. 6, 9, p. 11704-11715 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Unraveling the Spontaneous Zwitterionic Copolymerization Mechanism of Cyclic Imino Ethers and Acrylic Acid

Steinkoenig, J., De Jongh, P. A. J. M., Haddleton, D. M., Goldmann, A. S., Barner-Kowollik, C. & Kempe, K., 23 Jan 2018, In : Macromolecules. 51, 2, p. 318-327 10 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Uptake and transcytosis of functionalized superparamagnetic iron oxide nanoparticles in an: In vitro blood brain barrier model

Ivask, A., Pilkington, E. H., Blin, T., Käkinen, A., Vija, H., Visnapuu, M., Quinn, J. F., Whittaker, M. R., Qiao, R., Davis, T. P., Ke, P. C. & Voelcker, N. H., 1 Feb 2018, In : Biomaterials Science. 6, 2, p. 314-323 10 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)
2017
10 Citations (Scopus)

Aerosolized polymyxin B for treatment of respiratory tract infections: Determination of pharmacokinetic-pharmacodynamic indices for aerosolized polymyxin B against Pseudomonas aeruginosa in a mouse lung infection model

Lin, Y. W., Zhou, Q., Onufrak, N. J., Wirth, V., Chen, K., Wang, J., Forrest, A., Chan, H-K. & Li, J., 1 Aug 2017, In : Antimicrobial Agents and Chemotherapy. 61, 8, 15 p., e00211-17.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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2 Citations (Scopus)

Affinity Binding of EMR2 Expressing Cells by Surface-Grafted Chondroitin Sulfate B

Burzava, A. L. S., Jasieniak, M., Cockshell, M. P., Bonder, C. S., Harding, F. J., Griesser, H. J. & Voelcker, N. H., 12 Jun 2017, In : Biomacromolecules. 18, 6, p. 1697-1704 8 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

A fresh shine on cystic fibrosis inhalation therapy: Antimicrobial synergy of polymyxin B in combination with silver nanoparticles

Jasim, R., Schneider, E. K., Han, M., Azad, M. A. K., Hussein, M., Nowell, C., Baker, M. A., Wang, J., Li, J. & Velkov, T., 1 Apr 2017, In : Journal of Biomedical Nanotechnology. 13, 4, p. 447-457 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate

Lee, S. N., Chakrabarty, B., Wittmer, B., Papargiris, M., Ryan, A., Frydenberg, M., Frydenberg, M., Lawrentschuk, N., Middendorff, R., Risbridger, G. P., Ellem, S. J. & Exintaris, B., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 10150.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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19 Citations (Scopus)

A hydrogel-based localized release of colistin for antimicrobial treatment of burn wound infection

Zhu, C., Zhao, J., Kempe, K., Wilson, P., Wang, J., Velkov, T., Li, J., Davis, T. P., Whittaker, M. R. & Haddleton, D. M., 2017, In : Macromolecular Bioscience. 17, 2, 7 p., 1600320.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
6 Citations (Scopus)

A mass spectrometry-based forensic toolbox for imaging and detecting biological fluid evidence in finger marks and fingernail scrapings

Kamanna, S., Henry, J., Voelcker, N. H., Linacre, A. & Paul Kirkbride, K., Sep 2017, In : International Journal of Legal Medicine. 131, 5, p. 1413-1422 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Aminoglycoside concentrations required for synergy with carbapenems against Pseudomonas aeruginosa determined via mechanistic studies and modeling

Yadav, R., Bulitta, J. B., Schneider, E. K., Shin, B. S., Velkov, T., Nation, R. L. & Landersdorfer, C. B., 1 Dec 2017, In : Antimicrobial Agents and Chemotherapy. 61, 12, 16 p., e00722.

Research output: Contribution to journalArticleResearchpeer-review

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2 Citations (Scopus)

A nanomechanical study of the effects of colistin on the Klebsiella pneumoniae AJ218 capsule

Mularski, A., Wilksch, J., Hanssen, E., Li, J., Tomita, T., Pidot, S. J., Stinear, T., Separovic, F. & Strugnell, D., 1 May 2017, In : European Biophysics Journal. 46, 4, p. 351-361 11 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration

Chan, L. J., Feeney, O. M., Leong, N. J., McLeod, V. M., Porter, C. J. H., Williams, C. C. & Kaminskas, L. M., 11 Sep 2017, In : Biomacromolecules. 18, 9, p. 2866-2875 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

A new lipid excipient, phosphorylated tocopherol mixture, TPM enhances the solubilisation and oral bioavailability of poorly water soluble CoQ10 in a lipid formulation

Pham, A. C., Gavin, P., Libinaki, R., Ramirez, G. & Boyd, B. J., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 400-406 7 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Anionic multiblock core cross-linked star copolymers: Via RAFT polymerization

Bray, C., Peltier, R., Kim, H., Mastrangelo, A. & Perrier, S., 28 Sep 2017, In : Polymer Chemistry. 8, 36, p. 5513-5524 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Antibody-dependent phagocytosis (ADP) responses following trivalent inactivated influenza vaccination of younger and older adults

Ana-Sosa-Batiz, F., Johnston, A. P. R., Hogarth, P. M., Wines, B. D., Barr, I., Wheatley, A. K. & Kent, S. J., Nov 2017, In : Vaccine. 35, 47, p. 6451-6458 8 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes

Macri, C., Dumont, C., Panozza, S., Lahoud, M. H., Caminschi, I., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., Jan 2017, In : Molecular Immunology. 81, p. 143-150 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

Niclis, J. C., Gantner, C. W., Hunt, C. P. J., Kauhausen, J. A., Durnall, J. C., Haynes, J. M., Pouton, C. W., Parish, C. L. & Thompson, L. H., 12 Sep 2017, In : Stem Cell Reports. 9, 3, p. 868-882 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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3 Citations (Scopus)

Assessing the impact of lithium chloride on the expression of P-glycoprotein at the blood-brain barrier

Newman, S. A., Pan, Y., Short, J. L. & Nicolazzo, J. A., Sep 2017, In : Journal of Pharmaceutical Sciences. 106, 9, p. 2625–2631 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A strategy to evaluate the surface energy of high packing efficiency fine powders via inverse gas chromatography

Tan, G., Qu, L., Morton, D. A. V. & Larson, I., 1 Oct 2017, In : Powder Technology. 320, p. 470-473 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A suicidal strain of Listeria monocytogenes is effective as a DNA vaccine delivery system for oral administration

Sinha, S., Kuo, C. Y., Ho, J. K., White, P. J., Jazayeri, J. A. & Pouton, C. W., 2017, In : Vaccine. 35, 38, 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

A traceless reversible polymeric colistin prodrug to combat multidrug-resistant (MDR) gram-negative bacteria

Zhu, C., Schneider, E. K., Wang, J., Kempe, K., Wilson, P., Velkov, T., Li, J., Davis, T., Whittaker, M. R. & Haddleton, D. M., 2017, In : Journal of Controlled Release. 259, 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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7 Citations (Scopus)

"Bottom-up" in situ proteomic differentiation of human and non-human haemoglobins for forensic purposes by matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry

Kamanna, S., Henry, J., Voelcker, N., Linacre, A. & Kirkbride, K. P., 30 Nov 2017, In : Rapid Communications in Mass Spectrometry. 31, 22, p. 1927-1937 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Cationic acrylate oligomers comprising amino acid mimic moieties demonstrate improved antibacterial killing efficiency

Grace, J., Elliott, A. G., Huang, J. X., Schneider, E. K., Truong Phuoc, N., Cooper, M. A., Li, J., Davis, T., Quinn, J., Velkov, T. & Whittaker, M. R., 2017, In : Journal of Materials Chemistry B. 5, 3, p. 531-536 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid

Clulow, A. J., Parrow, A., Hawley, A., Khan, J., Pham, A. C., Larsson, P., Bergström, C. A. S. & Boyd, B. J., 7 Dec 2017, In : Journal of Physical Chemistry B. 121, 48, p. 10869-10881 13 p.

Research output: Contribution to journalArticleResearchpeer-review