Research Output 1975 2019

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2017

Effects of protein corona on IAPP amyloid aggregation, fibril remodelling, and cytotoxicity

Pilkington, E. H., Xing, Y., Wang, B., Kakinen, A., Wang, M., Davis, T. P., Ding, F. & Ke, P-C., 1 Dec 2017, In : Scientific Reports. 7, 1, 13 p., 2455.

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Efficiently specified ventral midbrain dopamine neurons from human pluripotent stem cells under Xeno-free conditions restore motor deficits in Parkinsonian rodents

Niclis, J. C., Gantner, C. W., Alsanie, W. F., McDougall, S. J., Bye, C. R., Elefanty, A. G., Stanley, E. G., Haynes, J. M., Pouton, C. W., Thompson, L. H. & Parish, C. L., 1 Mar 2017, In : Stem Cells Translational Medicine. 6, 3, p. 937-948 12 p.

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Electrochemical fingerprints of brominated trihaloacetic acids (HAA3) mixtures in water

Cetó, X., Saint, C., Chow, C. W. K., Voelcker, N. H. & Prieto-Simón, B., 2017, In : Sensors and Actuators B: Chemical. 247, p. 70-77 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy

To, E. E., Vlahos, R., Luong, R., Halls, M. L., Reading, P. C., King, P. T., Chan, C., Drummond, G. R., Sobey, C. G., Broughton, B. R. S., Starkey, M. R., van der Sluis, R., Lewin, S. R., Bozinovski, S., O'Neill, L. A. J., Quach, T., Porter, C. J. H., Brooks, D. A., O'Leary, J. & Selemidis, S., 1 Dec 2017, In : Nature Communications. 8, 1, 17 p., 69.

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Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission

Yarwood, R. E., Imlach, W. L., Lieu, T., Veldhuis, N. A., Jensen, D. D., Herenbrink, C. K., Aurelio, L., Cai, Z., Christie, M. J., Poole, D. P., Porter, C. J. H., McLean, P., Hicks, G. A., Geppetti, P., Halls, M. L., Canals, M. & Bunnett, N. W., 14 Nov 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 46, p. 12309-12314 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Engineered hydrogen-bonded glycopolymer capsules and their interactions with antigen presenting cells

Kempe, K., Xiang, S. D., Wilson, P., Rahim, M. A., Ju, Y., Whittaker, M. R., Haddleton, D. M., Plebanski, M., Caruso, F. & Davis, T. P., 22 Feb 2017, In : ACS Applied Materials and Interfaces. 9, 7, p. 6444-6452 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Evolution of Microphase Separation with Variations of Segments of Sequence-Controlled Multiblock Copolymers

Zhang, J., Deubler, R., Hartlieb, M., Martin, L., Tanaka, J., Patyukova, E., Topham, P. D., Schacher, F. H. & Perrier, S., 26 Sep 2017, In : Macromolecules. 50, 18, p. 7380-7387 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Extending the Excitation Wavelength of Potential Photosensitizers via Appendage of a Kinetically Stable Terbium(III) Macrocyclic Complex for Applications in Photodynamic Therapy

Ung, P., Clerc, M., Huang, H., Qiu, K., Chao, H., Seitz, M., Boyd, B. J., Graham, B. & Gasser, G., 17 Jul 2017, In : Inorganic Chemistry. 56, 14, p. 7960-7974 15 p.

Research output: Contribution to journalArticleResearchpeer-review

From Breast Cancer to Antimicrobial: Combating Extremely Resistant Gram-Negative "superbugs" Using Novel Combinations of Polymyxin B with Selective Estrogen Receptor Modulators

Hussein, M. H., Schneider, E. K., Elliott, A. G., Han, M., Reyes-Ortega, F., Morris, F., Blastovich, M. A. T., Jasim, R., Currie, B. J., Mayo, M., Baker, M., Cooper, M. A., Li, J. & Velkov, T., 1 Jul 2017, In : Microbial Drug Resistance. 23, 5, p. 640-650 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Functional and genetic evidence that nucleoside transport is highly conserved in Leishmania species: Implications for pyrimidine-based chemotherapy

Alzahrani, K. J. H., Ali, J. A. M., Eze, A. A., Looi, W. L., Tagoe, D. N. A., Creek, D. J., Barrett, M. P. & De Koning, H. P., 1 Aug 2017, In : International Journal for Parasitology: Drugs and Drug Resistance. 7, 2, p. 206-226 21 p.

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Functional characterization of the unique terminal thioesterase domain from polymyxin synthetase

Galea, C., Roberts, K. D., Zhu, Y., Thompson, P. E., Li, J. & Velkov, T., 31 Jan 2017, In : Biochemistry. 56, 4, p. 657-668 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Functional multisite copolymer by one-pot sequential RAFT copolymerization of styrene and maleic anhydride

Moriceau, G., Gody, G., Hartlieb, M., Winn, J., Kim, H., Mastrangelo, A., Smith, T. & Perrier, S., 28 Jul 2017, In : Polymer Chemistry. 8, 28, p. 4152-4161 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Garlic-inspired trisulfide linkers for thiol-stimulated H2S release

Ercole, F., Whittaker, M. R., Halls, M. L., Boyd, B. J., Davis, T. P. & Quinn, J. F., 2017, In : Chemical Communications. 53, 57, p. 8030-8033 4 p.

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Gelofusine ameliorates colistin-induced nephrotoxicity

Sivanesan, S. S., Azad, M. A. K., Schneider, E. K., Ahmed, M. U., Huang, J., Wang, J., Li, J., Nation, R. L. & Velkov, T., 1 Dec 2017, In : Antimicrobial Agents and Chemotherapy. 61, 12, 7 p., e00985.

Research output: Contribution to journalArticleResearchpeer-review

Global Gene Expression Profile of Acinetobacter baumannii During Bacteremia

Murray, G. L., Tsyganov, K., Kostoulias, X. P., Bulach, D. M., Powell, D., Creek, D. J., Boyce, J. D., Paulsen, I. T. & Peleg, A. Y., 15 Feb 2017, In : Journal of Infectious Diseases. 215, 1, p. S52-S57

Research output: Contribution to journalArticleResearchpeer-review

Gold-decorated porous silicon nanopillars for targeted hyperthermal treatment of bacterial infections

Alhmoud, H., Cifuentes-Rius, A., Delalat, B. & Voelcker, N. H., 1 Jan 2017, In : ACS Applied Materials and Interfaces. 9, 39, p. 33707-33716 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Gold Nanocluster-Mediated Cellular Death under Electromagnetic Radiation

Cifuentes-Rius, A., Ivask, A., Das, S., Pena Auladell, N., Fabregas, L., Fletcher, N., Houston, Z., Thurecht, K. J. & Voelcker, N. H., 29 Nov 2017, In : ACS Applied Materials and Interfaces. 9, 47, p. 41159-41167 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Graphene as a photothermal actuator for control of lipid mesophase structure

Quinn, M. D. J., Wang, T., Du, J. D., Boyd, B. J., Hawley, A. & Notley, S. M., 7 Jan 2017, In : Nanoscale. 9, 1, p. 341-348 8 p.

Research output: Contribution to journalArticleResearchpeer-review

High-dose ampicillin-sulbactam combinations combat polymyxin-resistant Acinetobacter baumannii in a hollow-fiber infection model

Lenhard, J. R., Smith, N. M., Bulman, Z. P., Tao, X., Thamlikitkul, V., Shin, B. S., Nation, R. L., Li, J., Bulitta, J. B. & Tsuji, B. T., 1 Mar 2017, In : Antimicrobial Agents and Chemotherapy. 61, 3, 6 p., e01268.

Research output: Contribution to journalArticleResearchpeer-review

High-intensity meropenem combinations with polymyxin B: new strategies to overcome carbapenem resistance in Acinetobacter baumannii

Lenhard, J. R., Bulitta, J. B., Connell, T. D., King-Lyons, N., Landersdorfer, C., Cheah, S-E., Thamlikitkul, V., Shin, B. S., Rao, G., Holden, P. N., Walsh, T. J., Forrest, A., Nation, R. L., Li, J. & Tsuji, B. T., 2017, In : Journal of Antimicrobial Chemotherapy. 72, 1, p. 153-165 13 p.

Research output: Contribution to journalArticleResearchpeer-review

High Tg poly(ester amide)s by melt polycondensation of monomers from renewable resources; citric acid, D-glucono-δ-lactone and amino acids: A DSC study

de Jongh, P. A. J. M., Paul, P. K. C., Khoshdel, E., Wilson, P., Kempe, K. & Haddleton, D. M., 1 Sep 2017, In : European Polymer Journal. 94, p. 11-19 9 p.

Research output: Contribution to journalArticleResearchpeer-review

High throughput, quantitative analysis of human osteoclast differentiation and activity

Diepenhorst, N., Nowell, C., Rueda, P., Henriksen, K., Pierce, T., Cook, A., Pastoureau, P., Sabatini, M., Charman, W., Christopoulos, A., Summers, R., Sexton, P. & Langmead, C., 15 Feb 2017, In : Analytical Biochemistry. 519, p. 51-56 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Hydrolyzable Poly[Poly(Ethylene Glycol) Methyl Ether Acrylate]-Colistin Prodrugs through Copper-Mediated Photoinduced Living Radical Polymerization

Zhu, C., Schneider, E. K., Nikolaou, V., Klein, T., Li, J., Davis, T. P., Whittaker, M. R., Wilson, P., Kempe, K., Velkov, T. & Haddleton, D. M., 19 Jul 2017, In : Bioconjugate Chemistry. 28, 7, p. 1916-1924 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Inclusion of digestible surfactants in solid SMEDDS formulation removes lag time and influences the formation of structured particles during digestion

Vithani, K., Hawley, A., Jannin, V., Pouton, C. & Boyd, B. J., 1 May 2017, In : The AAPS Journal. 19, 3, p. 754-764 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of Size and Shape on the Biodistribution of Nanoparticles Prepared by Polymerization-Induced Self-Assembly

Kaga, S., Truong, N. P., Esser, L., Senyschyn, D., Sanyal, A., Sanyal, R., Quinn, J. F., Davis, T. P., Kaminskas, L. M. & Whittaker, M. R., 11 Dec 2017, In : Biomacromolecules. 18, 12, p. 3963-3970 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes

Han, M. L., Shen, H. H., Hansford, K. A., Schneider, E. K., Sivanesan, S., Roberts, K. D., Thompson, P. E., Le Brun, A. P., Zhu, Y., Sani, M-A., Separovic, F., Blaskovich, M. A. T., Baker, M. A., Moskowitz, S. M., Cooper, M. A., Li, J. & Velkov, T., 11 Aug 2017, In : ACS Infectious Diseases. 3, 8, p. 606-619 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigation of donor-acceptor Stenhouse adducts as new visible wavelength-responsive switching elements for lipid-based liquid crystalline systems

Jia, S., Du, J. D., Hawley, A., Fong, W-K., Graham, B. & Boyd, B. J., 7 Mar 2017, In : Langmuir: the ACS journal of surfaces and colloids. 33, 9, p. 2215-2221 7 p.

Research output: Contribution to journalArticleResearchpeer-review

In vivo fate of carbon nanotubes with different physicochemical properties for gene delivery applications

Cifuentes-Rius, A., Boase, N. R. B., Font, I., Coronas, N., Ramos-Perez, V., Thurecht, K. J. & Borrós, S., 5 Apr 2017, In : ACS Applied Materials and Interfaces. 9, 13, p. 11461-11471 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies

Sahbaz, Y., Nguyen, T. H., Ford, L., McEvoy, C. L., Williams, H. D., Scammells, P. J. & Porter, C. J. H., 6 Nov 2017, In : Molecular Pharmaceutics. 14, 11, p. 3669-3683 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Isoform-specific biased agonism of histamine H3 receptor agonists

Riddy, D. M., Cook, A. E., Diepenhorst, N. A., Bosnyak, S., Brady, R., La Cour, C. M., Mocaer, E., Summers, R. J., Charman, W. N., Sexton, P. M., Christopoulos, A. & Langmead, C. J., 1 Feb 2017, In : Molecular Pharmacology. 91, 2, p. 87-99 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Life under the Microscope: Quantifying Live Cell Interactions to Improve Nanoscale Drug Delivery

Johnston, A. P. R., 27 Jan 2017, In : ACS Sensors. 2, 1, p. 4-9 6 p.

Research output: Contribution to journalArticleResearchpeer-review

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Light-Mediated Atom Transfer Radical Polymerization of Semi-Fluorinated (Meth)acrylates: Facile Access to Functional Materials

Discekici, E. H., Anastasaki, A., Kaminker, R., Willenbacher, J., Truong, N. P., Fleischmann, C., Oschmann, B., Lunn, D. J., Read De Alaniz, J., Davis, T. P., Bates, C. M. & Hawker, C. J., 26 Apr 2017, In : Journal of the American Chemical Society. 139, 16, p. 5939-5945 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipidated polymers for the stabilization of cubosomes: Nanostructured drug delivery vehicles

Grace, J. L., Alcaraz, N., Truong, N. P., Davis, T. P., Boyd, B. J., Quinn, J. F. & Whittaker, M. R., 2017, In : Chemical Communications. 53, 76, p. 10552-10555 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Lithium in paediatric patients with bipolar disorder: implications for selection of dosage regimens via population pharmacokinetics/pharmacodynamics

Landersdorfer, C. B., Findling, R. L., Frazier, J. A., Kafantaris, V. & Kirkpatrick, C. M. J., Jan 2017, In : Clinical Pharmacokinetics. 56, 1, p. 77-90 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Looped flow RAFT polymerization for multiblock copolymer synthesis

Kuroki, A., Martinez-Botella, I., Hornung, C. H., Martin, L., Williams, E. G. L., Locock, K. E. S., Hartlieb, M. & Perrier, S., 2017, In : Polymer Chemistry. 8, 21, p. 3249-3254 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site

Ryan, G. M., McLeod, V. M., Mehta, D., Kelly, B. D., Stanislawski, P. C., Owen, D. J., Kaminskas, L. M. & Porter, C. J. H., 1 Nov 2017, In : Nanomedicine-Nanotechnology Biology and Medicine. 13, 8, p. 2485-2494 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Lysine to arginine mutagenesis of chlorotoxin enhances its cellular uptake

Ojeda, P. G., Henriques, S. T., Pan, Y., Nicolazzo, J. A., Craik, D. J. & Wang, C. K., 1 Sep 2017, In : Biopolymers. 108, 5, 10 p., e23025.

Research output: Contribution to journalArticleResearchpeer-review

Lysophosphatidylcholine modulates the aggregation of human islet amyloid polypeptide

Xing, Y., Pilkington, E. H., Wang, M., Nowell, C. J., Kakinen, A., Sun, Y., Wang, B., Davis, T. P., Ding, F. & Ke, P. C., 7 Dec 2017, In : Physical Chemistry Chemical Physics. 19, 45, p. 30627-30635 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolite mapping by consecutive nanostructure and silver-assisted mass spectrometry imaging on tissue sections

Gustafsson, O. J. R., Guinan, T. M., Rudd, D., Kobus, H., Benkendorff, K. & Voelcker, N. H., 30 Jun 2017, In : Rapid Communications in Mass Spectrometry. 31, 12, p. 991-1000 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolomics-based elucidation of active metabolic pathways in erythrocytes and HSC-derived reticulocytes

Srivastava, A., Evans, K. J., Sexton, A. E., Schofield, L. D. & Creek, D. J., 7 Apr 2017, In : Journal of Proteome Research. 16, 4, p. 1492-1505 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Methacrylic block copolymers by sulfur free RAFT (SF RAFT) free radical emulsion polymerisation

Nurumbetov, G., Engelis, N., Godfrey, J., Hand, R., Anastasaki, A., Simula, A., Nikolaou, V. & Haddleton, D. M., 14 Feb 2017, In : Polymer Chemistry. 8, 6, p. 1084-1094 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Microcontainers as an oral delivery system for spray dried cubosomes containing ovalbumin

Nielsen, L. H., Rades, T., Boyd, B. & Boisen, A., Sep 2017, In : European Journal of Pharmaceutics and Biopharmaceutics. 118, p. 13-20 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Minocycline attenuates colistin-induced neurotoxicity via suppression of apoptosis, mitochondrial dysfunction and oxidative stress

Dai, C., Ciccotosto, G. D., Cappai, R., Wang, Y., Tang, S., Xiao, X. & Velkov, T., 2017, In : Journal of Antimicrobial Chemotherapy. 72, 6, p. 1635-1645 11 p., dkx037.

Research output: Contribution to journalArticleResearchpeer-review

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Modular photo-induced RAFT polymerised hydrogels: Via thiol-ene click chemistry for 3D cell culturing

Tan, V. T. G., Nguyen, D. H. T., Utama, R. H., Kahram, M., Ercole, F., Quinn, J. F., Whittaker, M. R., Davis, T. P. & Justin Gooding, J., 21 Oct 2017, In : Polymer Chemistry. 8, 39, p. 6123-6133 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Modulating protein amyloid aggregation with nanomaterials

Wang, B., Pilkington, E. H., Sun, Y., Davis, T. P. T., Ke, P. C. & Ding, F., 1 Sep 2017, In : Environmental Science: Nano. 4, 9, p. 1772-1783 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Multi-omics based identification of specific biochemical changes associated with PfKelch13-mutant artemisinin-resistant Plasmodium falciparum

Siddiqui, G., Srivastava, A., Russell, A. S. & Creek, D. J., 1 May 2017, In : Journal of Infectious Diseases. 215, 9, p. 1435-1444 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Mutations in DCC cause isolated agenesis of the corpus callosum with incomplete penetrance

Marsh, A. P. L., Heron, D., Edwards, T. J., Quartier, A., Galea, C., Nava, C., Rastetter, A., Moutard, M. L., Anderson, V., Bitoun, P., Bunt, J., Faudet, A., Garel, C., Gillies, G., Gobius, I., Guegan, J., Heide, S., Keren, B., Lesne, F., Lukic, V. & 33 othersMandelstam, S. A., McGillivray, G., McIlroy, A., Méneret, A., Mignot, C., Morcom, L. R., Odent, S., Paolino, A., Pope, K., Riant, F., Robinson, G. A., Spencer-Smith, M., Srour, M., Stephenson, S. E. M., Tankard, R., Trouillard, O., Welniarz, Q., Wood, A., Brice, A., Rouleau, G., Attié-Bitach, T., Delatycki, M. B., Mandel, J. L., Amor, D. J., Roze, E., Piton, A., Bahlo, M., Billette De Villemeur, T., Sherr, E. H., Leventer, R. J., Richards, L. J., Lockhart, P. J. & Depienne, C., Apr 2017, In : Nature Genetics. 49, 4, p. 511-514 4 p.

Research output: Contribution to journalArticleResearchpeer-review

NanoEHS beyond toxicity-focusing on biocorona

Lin, S., Mortimer, M., Chen, R., Kakinen, A., Riviere, J. E., Davis, T. P., Ding, F. & Ke, P-C., 2017, In : Environmental Science: Nano. 4, 7, p. 1433-1454 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanotopography mediated osteogenic differentiation of human dental pulp derived stem cells

Bachhuka, A., Delalat, B., Ghaemi, S. R., Gronthos, S., Voelcker, N. H. & Vasilev, K., 7 Oct 2017, In : Nanoscale. 9, 37, p. 14248-14258 11 p.

Research output: Contribution to journalArticleResearchpeer-review

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