Research Output 1975 2019

Filter
Article
2018
1 Citation (Scopus)

Nano-assemblies of cationic mPEG brush block copolymers with gadolinium polyoxotungstate [Gd(W5O18)2]9- form stable, high relaxivity MRI contrast agents

Ly, J., Li, Y., Vu, M. N., Moffat, B. A., Jack, K. S., Quinn, J. F., Whittaker, M. R. & Davis, T. P., 21 Apr 2018, In : Nanoscale. 10, 15, p. 7270-7280 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Nanoscale inhibition of polymorphic and ambidextrous IAPP amyloid aggregation with small molecules

Kakinen, A., Adamcik, J., Wang, B., Ge, X., Mezzenga, R., Davis, T. P., Ding, F. & Ke, P. C., Jul 2018, In : Nano Research. 11, 7, p. 3636-3647 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Naphthalocyanine as a New Photothermal Actuator for Lipid-Based Drug Delivery Systems

Du, J. D., Hong, L., Tan, A. & Boyd, B. J., 8 Feb 2018, In : Journal of Physical Chemistry B. 122, 5, p. 1766-1770 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Near-field mapping of localized plasmon resonances in metal-free, nano-membrane graphene for mid-infrared sensing applications

Desouky, M., Anisur, M. R., Alba, M., Singh Raman, R. K., Swillam, M. A., Voelcker, N. H. & Kasry, A., 1 Jan 2018, In : ACS Applied Nano Materials. 1, 11, p. 6454-6462 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Norbornane-based cationic antimicrobial peptidomimetics targeting the bacterial membrane

Hickey, S. M., Ashton, T. D., Boer, G., Bader, C. A., Thomas, M., Elliott, A. G., Schmuck, C., Yu, H. Y., Li, J., Nation, R. L., Cooper, M. A., Plush, S. E., Brooks, D. A. & Pfeffer, F. M., 5 Dec 2018, In : European Journal of Medicinal Chemistry. 160, p. 9-22 14 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

NormalizeMets: assessing, selecting and implementing statistical methods for normalizing metabolomics data

De Livera, A. M., Olshansky, G., Simpson, J. A. & Creek, D. J., 1 May 2018, In : Metabolomics. 14, 5, 5 p., 54.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Novel agrochemical conjugates with self-assembling behaviour

Liu, Q., Graham, B., Hawley, A., Dong, Y. D. & Boyd, B. J., 15 Feb 2018, In : Journal of Colloid and Interface Science. 512, p. 369-378 10 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Novel peptidylated surfaces for interference-free electrochemical detection of cardiac troponin I

Dhawan, S., Sadanandan, S., Haridas, V., Voelcker, N. H. & Prieto-Simón, B., 15 Jan 2018, In : Biosensors and Bioelectronics. 99, p. 486-492 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Novel polymyxin combination with antineoplastic mitotane improved the bacterial killing against polymyxin-resistant multidrug-resistant gram-negative pathogens

Tran, T. B., Wang, J., Doi, Y., Velkov, T., Bergen, P. J. & Li, J., 12 Apr 2018, In : Frontiers in Microbiology. 9, 11 p., 721.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Novel self-assembling conjugates as vectors for agrochemical delivery

Nadiminti, P. P., Liu, Q., Vanjari, L. K., Dong, Y. D., Boyd, B. J. & Cahill, D. M., 21 Nov 2018, In : Journal of Nanobiotechnology. 16, 1, 15 p., 94.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Optimization and evaluation of piperacillin-tobramycin combination dosage regimens against Pseudomonas aeruginosa for patients with altered pharmacokinetics via the hollow-fiber infection model and mechanism-based modeling

Yadav, R., Rogers, K. E., Bergen, P. J., Bulitta, J. B., Kirkpatrick, C. M. J., Wallis, S. C., Paterson, D. L., Nation, R. L., Lipman, J., Roberts, J. A. & Landersdorfer, C. B., 1 May 2018, In : Antimicrobial Agents and Chemotherapy. 62, 5, 12 p., e00078.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Optimization of a meropenem-tobramycin combination dosage regimen against hypermutable and nonhypermutable pseudomonas aeruginosa via mechanism-based modeling and the hollow-fiber infection model

Landersdorfer, C. B., Rees, V. E., Yadav, R., Rogers, K. E., Kim, T. H., Bergen, P. J., Cheah, S-E., Boyce, J. D., Peleg, A. Y., Oliver, A., Shin, B. S., Nation, R. L. & Bulitta, J. B., 1 Apr 2018, In : Antimicrobial Agents and Chemotherapy. 62, 4, 13 p., e02055-17.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Optimization of binding B-lymphocytes in a microfluidic channel: Surface modification, stasis time and shear response

McCormick, S., Tong, Z., Ivask, A., Morozesk, M., Voelcker, N. H., Lombi, E. & Priest, C., 1 Jan 2018, In : Biofabrication. 10, 1, 10 p., 014101.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Overcoming Surfactant-Induced Morphology Instability of Noncrosslinked Diblock Copolymer Nano-Objects Obtained by RAFT Emulsion Polymerization

Truong, N. P., Zhang, C., Nguyen, T. A. H., Anastasaki, A., Schulze, M. W., Quinn, J. F., Whittaker, A. K., Hawker, C. J., Whittaker, M. R. & Davis, T. P., 20 Feb 2018, In : ACS Macro Letters. 7, 2, p. 159-165 7 p.

Research output: Contribution to journalArticleResearchpeer-review

24 Citations (Scopus)

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases

Furtado, D., Björnmalm, M., Ayton, S., Bush, A. I., Kempe, K. & Caruso, F., 15 Nov 2018, In : Advanced Materials. 30, 46, 66 p., 1801362.

Research output: Contribution to journalArticleResearchpeer-review

Oxygen-permeable microwell device maintains islet mass and integrity during shipping

Rojas-Canales, D. M., Waibel, M., Forget, A., Penko, D., Nitschke, J., Harding, F. J., Delalat, B., Blencowe, A., Loudovaris, T., Grey, S. T., Thomas, H. E., Kay, T. W. H., Drogemuller, C. J., Voelcker, N. H. & Coates, P. T., 1 Mar 2018, In : Endocrine Connections. 7, 3, p. 490-503 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
3 Citations (Scopus)

Parasite-mediated degradation of synthetic ozonide antimalarials impacts in vitro antimalarial activity

Giannangelo, C., Stingelin, L., Yang, T., Tilley, L., Charman, S. A. & Creek, D. J., 1 Mar 2018, In : Antimicrobial Agents and Chemotherapy. 62, 3, 14 p., e01566-17.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Performance optimisation of porous silicon rugate filter biosensor for the detection of insulin

Chhasatia, R., Sweetman, M. J., Prieto-Simon, B. & Voelcker, N. H., 10 Nov 2018, In : Sensors and Actuators B: Chemical. 273, p. 1313-1322 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Personalizing Polymyxin B dosing using an adaptive feedback control algorithm

Lakota, E. A., Landersdorfer, C. B., Nation, R. L., Li, J., Kaye, K. S., Rao, G. G. & Forrest, A., 1 Jul 2018, In : Antimicrobial Agents and Chemotherapy. 62, 7, 9 p., e00483-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
19 Citations (Scopus)

Pharmacokinetics/pharmacodynamics of systemically administered polymyxin B against Klebsiella pneumoniae in mouse thigh and lung infection models

Landersdorfer, C. B., Wang, J., Wirth, V., Chen, K., Kaye, K. S., Tsuji, B., Li, J. & Nation, R. L., 1 Feb 2018, In : Journal of Antimicrobial Chemotherapy. 73, 2, p. 462-468 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
3 Citations (Scopus)

pH-Responsive Polyacetal–Protein Conjugates Designed for Polymer Masked–Unmasked Protein Therapy (PUMPT)

Escalona, G. R., Sanchis, J. & Vicent, M. J., 1 Jan 2018, In : Macromolecular Bioscience. 18, 1, 11 p., 1700302.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

PI3K activation in neural stem cells drives tumorigenesis which can be ameliorated by targeting the cAMP response element binding protein

Daniel, P. M., Filiz, G., Brown, D. V., Christie, M., Waring, P. M., Zhang, Y., Haynes, J. M., Pouton, C., Flanagan, D., Vincan, E., Johns, T. G., Montgomery, K., Phillips, W. A. & Mantamadiotis, T., 1 Jan 2018, In : Neuro-Oncology. 20, 10, p. 1344-1355 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)
Open Access
File
1 Citation (Scopus)

Polymorphism rs1385129 within glut1 gene SLC2A1 is linked to poor CD4+ T cell recovery in antiretroviral-treated HIV+ individuals

Masson, J. J. R., Cherry, C. L., Murphy, N. M., Sada-Ovalle, I., Hussain, T., Palchaudhuri, R., Martinson, J., Landay, A. L., Billah, B., Crowe, S. M. & Palmer, C. S., 17 May 2018, In : Frontiers in Immunology. 9, MAY, 13 p., 900.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Polymyxin B and fosfomycin thwart KPC-producing Klebsiella pneumoniae in the hollow-fibre infection model

Bulman, Z. P., Zhao, M., Satlin, M. J., Chen, L., Kreiswirth, B. N., Walsh, T. J., Nation, R. L., Li, J. & Tsuji, B. T., 1 Jul 2018, In : International Journal of Antimicrobial Agents. 52, 1, p. 114-118 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Polymyxin B causes DNA damage in HK-2 cells and mice

Yun, B., Zhang, T., Azad, M. A. K., Wang, J., Nowell, C. J., Kalitsis, P., Velkov, T., Hudson, D. F. & Li, J., Jul 2018, In : Archives of Toxicology. 92, 7, p. 2259-2271 13 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Polymyxin-Induced Lipid A Deacylation in Pseudomonas aeruginosa Perturbs Polymyxin Penetration and Confers High-Level Resistance

Han, M-L., Velkov, T., Zhu, Y., Roberts, K. D., Le Brun, A. P., Chow, S. H., Gutu, A. D., Moskowitz, S. M., Shen, H-H. & Li, J., 19 Jan 2018, In : ACS Chemical Biology. 13, 1, p. 121-130 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Population pharmacokinetic analyses for ertapenem in subjects with a wide range of body sizes

Lakota, E. A., Landersdorfer, C. B., Zhang, L., Nafziger, A. N., Bertino, J. S., Bhavnani, S. M. & Forrest, A., 1 Oct 2018, In : Antimicrobial Agents and Chemotherapy. 62, 10, 11 p., e00784.

Research output: Contribution to journalArticleResearchpeer-review

Porous silicon-poly(ε-caprolactone) film composites: evaluation of drug release and degradation behavior

Bodiford, N. K., McInnes, S. J. P., Voelcker, N. H. & Coffer, J. L., 1 Sep 2018, In : Biomedical Microdevices. 20, 3, 9 p., 71.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Probing the Dynamic Nature of Self-Assembling Cyclic Peptide-Polymer Nanotubes in Solution and in Mammalian Cells

Rho, J. Y., Brendel, J. C., Macfarlane, L. R., Mansfield, E. D. H., Peltier, R., Rogers, S., Hartlieb, M. & Perrier, S., 2018, In : Advanced Functional Materials. 28, 24, 11 p., 1704569.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Profiling the Serum Protein Corona of Fibrillar Human Islet Amyloid Polypeptide

Pilkington, E. H., Gustafsson, O. J. R., Xing, Y., Hernandez-Fernaud, J., Zampronio, C., Kakinen, A., Faridi, A., Ding, F., Wilson, P., Ke, P. C. & Davis, T. P., 26 Jun 2018, In : ACS Nano. 12, 6, p. 6066-6078 13 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Prolonged and continuous antibacterial and anti-biofilm activities of thin films embedded with gentamicin-loaded mesoporous silica nanoparticles

Tamanna, T., Landersdorfer, C. B., Ng, H. J., Bulitta, J., Wood, P. & Yu, A., 1 Aug 2018, In : Applied Nanoscience. 8, 6, p. 1471-1482 12 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Proof-of-principle study in a murine lung infection model of antipseudomonal activity of phage PEV20 in a dry-powder formulation

Chang, R. Y. K., Chen, K., Wang, J., Wallin, M., Britton, W., Morales, S., Kutter, E., Li, J. & Chan, H. K., 1 Feb 2018, In : Antimicrobial Agents and Chemotherapy. 62, 2, 8 p., e01714-17.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome

Jimenez-Vargas, N. N., Pattison, L. A., Zhao, P., Lieu, T., Latorre, R., Jensen, D. D., Castro, J., Aurelio, L., Le, G. T., Flynn, B., Herenbrink, C. K., Yeatman, H. R., Edgington-Mitchell, L., Porter, C. J. H., Halls, M. L., Canals, M., Veldhuis, N. A., Poole, D. P., McLean, P., Hicks, G. A. & 7 others, Scheff, N., Chen, E., Bhattacharya, A., Schmidt, B. L., Brierley, S. M., Vanner, S. J. & Bunnett, N. W., 31 Jul 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 31, p. E7438-E7447 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Pseudomonas infection responsive liquid crystals for glycoside hydrolase and antibiotic combination

Thorn, C. R., Prestidge, C. A., Boyd, B. J. & Thomas, N., 1 Jan 2018, In : ACS Applied Bio Materials. 1, 2, p. 281-288 8 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)
2 Citations (Scopus)

Quality of oxytocin ampoules available in health care facilities in the Democratic Republic of Congo: an exploratory study in five provinces

Lambert, P., Nguyen, T. H., McEvoy, C., Minhas, R. S., Wright, P., Deadman, K., Masururu, L. M. & McIntosh, M. P., 1 Dec 2018, In : Journal of Global Health. 8, 2, p. 1-6 6 p., 020415.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Quantifying cellular internalization with a fluorescent click sensor

Selby, L. I., Aurelio, L., Yuen, D., Graham, B. & Johnston, A. P. R., 22 Jun 2018, In : ACS Sensors. 3, 6, p. 1182-1189 8 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Rapamycin Confers Neuroprotection against Colistin-Induced Oxidative Stress, Mitochondria Dysfunction, and Apoptosis through the Activation of Autophagy and mTOR/Akt/CREB Signaling Pathways

Dai, C., Ciccotosto, G. D., Cappai, R., Wang, Y., Tang, S., Hoyer, D., Schneider, E. K., Velkov, T. & Xiao, X., 18 Apr 2018, In : ACS Chemical Neuroscience. 9, 4, p. 824-837 14 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker

Mehta, D., Leong, N., McLeod, V. M., Kelly, B. D., Pathak, R., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Oct 2018, In : Molecular Pharmaceutics. 15, 10, p. 4568-4576 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Repurposing existing medications as cancer therapy: Design and feasibility of a randomized pilot investigating propranolol administration in patients receiving hematopoietic cell transplantation

Knight, J. M., Kerswill, S. A., Hari, P., Cole, S. W., Logan, B. R., D'Souza, A., Shah, N. N., Horowitz, M. M., Stolley, M. R., Sloan, E. K., Giles, K. E., Costanzo, E. S., Hamadani, M., Chhabra, S., Dhakal, B. & Rizzo, J. D., 24 May 2018, In : BMC Cancer. 18, 1, 12 p., 593.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
10 Citations (Scopus)

Secondary Self-Assembly of Supramolecular Nanotubes into Tubisomes and Their Activity on Cells

Brendel, J. C., Sanchis, J., Catrouillet, S., Czuba, E., Chen, M. Z., Long, B. M., Nowell, C., Johnston, A., Jolliffe, K. A. & Perrier, S., 17 Dec 2018, In : Angewandte Chemie - International Edition. 57, 51, p. 16678-16682 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Self-Crosslinking Lipopeptide/DNA/PEGylated Particles: A New Platform for DNA Vaccination Designed for Assembly in Aqueous Solution

Ho, J. K., White, P. J. & Pouton, C. W., 7 Sep 2018, In : Molecular Therapy - Nucleic Acids. 12, p. 504-517 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
7 Citations (Scopus)

Serum albumin impedes the amyloid aggregation and hemolysis of human islet amyloid polypeptide and alpha synuclein

Kakinen, A., Javed, I., Faridi, A., Davis, T. P. & Ke, P. C., Sep 2018, In : Biochimica et Biophysica Acta - Biomembranes. 1860, 9, p. 1803-1809 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

Solubilisation behaviour of poorly water-soluble drugs during digestion of solid SMEDDS

Vithani, K., Hawley, A., Jannin, V., Pouton, C. & Boyd, B. J., 1 Sep 2018, In : European Journal of Pharmaceutics and Biopharmaceutics. 130, p. 236-246 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Sonication-enabled rapid production of stable liquid metal nanoparticles grafted with poly(1-octadecene-: Alt -maleic anhydride) in aqueous solutions

Lin, Y., Genzer, J., Li, W., Qiao, R., Dickey, M. D. & Tang, S. Y., 14 Nov 2018, In : Nanoscale. 10, 42, p. 19871-19878 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Spontaneous zwitterionic copolymerisation: An undervalued and efficacious technique for the synthesis of functional degradable oligomers and polymers

de Jongh, P. A. J. M., Haddleton, D. M. & Kempe, K., 2018, In : Progress in Polymer Science. 87, p. 228-246 19 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Spray dried cubosomes with ovalbumin and Quil-A as a nanoparticulate dry powder vaccine formulation

von Halling Laier, C., Gibson, B., van de Weert, M., Boyd, B. J., Rades, T., Boisen, A., Hook, S. & Nielsen, L. H., 25 Oct 2018, In : International Journal of Pharmaceutics. 550, 1-2, p. 35-44 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Sputum Active Polymyxin Lipopeptides: Activity against Cystic Fibrosis Pseudomonas aeruginosa Isolates and Their Interactions with Sputum Biomolecules

Schneider-Futschik, E. K., Paulin, O. K. A., Hoyer, D., Roberts, K. D., Ziogas, J., Baker, M. A., Karas, J., Li, J. & Velkov, T., 11 May 2018, In : ACS Infectious Diseases. 4, 5, p. 646-655 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File