Research Output 1975 2019

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2018

Tristearin as a Model Cuticle for High-Throughput Screening of Agricultural Adjuvant Systems

Webster, G. R., Bisset, N. B., Cahill, D. M., Jones, P., Killick, A., Hawley, A. & Boyd, B. J., 5 Dec 2018, In : ACS Omega. 3, 12, p. 16672-16680 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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Tumor targeting with pH-responsive poly(2-oxazoline)-based nanogels for metronomic doxorubicin treatment

Hoelzer, D., Leiske, M. N., Hartlieb, M., Bus, T., Pretzel, D., Hoeppener, S., Kempe, K., Thierbach, R. & Schubert, U. S., 27 Apr 2018, In : Oncotarget. 9, 32, p. 22316-22331 16 p.

Research output: Contribution to journalArticleResearchpeer-review

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Tunable 2D binary colloidal alloys for soft nanotemplating

Fernández-Rodríguez, M. Á., Elnathan, R., Ditcovski, R., Grillo, F., Conley, G. M., Timpu, F., Rauh, A., Geisel, K., Ellenbogen, T., Grange, R., Scheffold, F., Karg, M., Richtering, W., Voelcker, N. H. & Isa, L., 21 Dec 2018, In : Nanoscale. 10, 47, p. 22189-22195 7 p.

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Understanding Effects of PAMAM Dendrimer Size and Surface Chemistry on Serum Protein Binding with Discrete Molecular Dynamics Simulations

Wang, B., Sun, Y., Davis, T. P., Ke, P. C., Wu, Y. & Ding, F., 4 Sep 2018, In : ACS Sustainable Chemistry & Engineering. 6, 9, p. 11704-11715 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Unraveling the Spontaneous Zwitterionic Copolymerization Mechanism of Cyclic Imino Ethers and Acrylic Acid

Steinkoenig, J., De Jongh, P. A. J. M., Haddleton, D. M., Goldmann, A. S., Barner-Kowollik, C. & Kempe, K., 23 Jan 2018, In : Macromolecules. 51, 2, p. 318-327 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Uptake and transcytosis of functionalized superparamagnetic iron oxide nanoparticles in an: In vitro blood brain barrier model

Ivask, A., Pilkington, E. H., Blin, T., Käkinen, A., Vija, H., Visnapuu, M., Quinn, J. F., Whittaker, M. R., Qiao, R., Davis, T. P., Ke, P. C. & Voelcker, N. H., 1 Feb 2018, In : Biomaterials Science. 6, 2, p. 314-323 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2017

Aerosolized polymyxin B for treatment of respiratory tract infections: Determination of pharmacokinetic-pharmacodynamic indices for aerosolized polymyxin B against Pseudomonas aeruginosa in a mouse lung infection model

Lin, Y. W., Zhou, Q., Onufrak, N. J., Wirth, V., Chen, K., Wang, J., Forrest, A., Chan, H-K. & Li, J., 1 Aug 2017, In : Antimicrobial Agents and Chemotherapy. 61, 8, 15 p., e00211-17.

Research output: Contribution to journalArticleResearchpeer-review

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Affinity Binding of EMR2 Expressing Cells by Surface-Grafted Chondroitin Sulfate B

Burzava, A. L. S., Jasieniak, M., Cockshell, M. P., Bonder, C. S., Harding, F. J., Griesser, H. J. & Voelcker, N. H., 12 Jun 2017, In : Biomacromolecules. 18, 6, p. 1697-1704 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A fresh shine on cystic fibrosis inhalation therapy: Antimicrobial synergy of polymyxin B in combination with silver nanoparticles

Jasim, R., Schneider, E. K., Han, M., Azad, M. A. K., Hussein, M., Nowell, C., Baker, M. A., Wang, J., Li, J. & Velkov, T., 1 Apr 2017, In : Journal of Biomedical Nanotechnology. 13, 4, p. 447-457 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Age Related Differences in Responsiveness to Sildenafil and Tamsulosin are due to Myogenic Smooth Muscle Tone in the Human Prostate

Lee, S. N., Chakrabarty, B., Wittmer, B., Papargiris, M., Ryan, A., Frydenberg, M., Frydenberg, M., Lawrentschuk, N., Middendorff, R., Risbridger, G. P., Ellem, S. J. & Exintaris, B., 1 Dec 2017, In : Scientific Reports. 7, 1, 9 p., 10150.

Research output: Contribution to journalArticleResearchpeer-review

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A hydrogel-based localized release of colistin for antimicrobial treatment of burn wound infection

Zhu, C., Zhao, J., Kempe, K., Wilson, P., Wang, J., Velkov, T., Li, J., Davis, T. P., Whittaker, M. R. & Haddleton, D. M., 2017, In : Macromolecular Bioscience. 17, 2, 7 p., 1600320.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

A mass spectrometry-based forensic toolbox for imaging and detecting biological fluid evidence in finger marks and fingernail scrapings

Kamanna, S., Henry, J., Voelcker, N. H., Linacre, A. & Paul Kirkbride, K., Sep 2017, In : International Journal of Legal Medicine. 131, 5, p. 1413-1422 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Aminoglycoside concentrations required for synergy with carbapenems against Pseudomonas aeruginosa determined via mechanistic studies and modeling

Yadav, R., Bulitta, J. B., Schneider, E. K., Shin, B. S., Velkov, T., Nation, R. L. & Landersdorfer, C. B., 1 Dec 2017, In : Antimicrobial Agents and Chemotherapy. 61, 12, 16 p., e00722.

Research output: Contribution to journalArticleResearchpeer-review

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A nanomechanical study of the effects of colistin on the Klebsiella pneumoniae AJ218 capsule

Mularski, A., Wilksch, J., Hanssen, E., Li, J., Tomita, T., Pidot, S. J., Stinear, T., Separovic, F. & Strugnell, D., 1 May 2017, In : European Biophysics Journal. 46, 4, p. 351-361 11 p.

Research output: Contribution to journalArticleResearchpeer-review

An Evaluation of Optimal PEGylation Strategies for Maximizing the Lymphatic Exposure and Antiviral Activity of Interferon after Subcutaneous Administration

Chan, L. J., Feeney, O. M., Leong, N. J., McLeod, V. M., Porter, C. J. H., Williams, C. C. & Kaminskas, L. M., 11 Sep 2017, In : Biomacromolecules. 18, 9, p. 2866-2875 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A new lipid excipient, phosphorylated tocopherol mixture, TPM enhances the solubilisation and oral bioavailability of poorly water soluble CoQ10 in a lipid formulation

Pham, A. C., Gavin, P., Libinaki, R., Ramirez, G. & Boyd, B. J., 28 Dec 2017, In : Journal of Controlled Release. 268, p. 400-406 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Anionic multiblock core cross-linked star copolymers: Via RAFT polymerization

Bray, C., Peltier, R., Kim, H., Mastrangelo, A. & Perrier, S., 28 Sep 2017, In : Polymer Chemistry. 8, 36, p. 5513-5524 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Antibody-dependent phagocytosis (ADP) responses following trivalent inactivated influenza vaccination of younger and older adults

Ana-Sosa-Batiz, F., Johnston, A. P. R., Hogarth, P. M., Wines, B. D., Barr, I., Wheatley, A. K. & Kent, S. J., Nov 2017, In : Vaccine. 35, 47, p. 6451-6458 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes

Macri, C., Dumont, C., Panozza, S., Lahoud, M. H., Caminschi, I., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., Jan 2017, In : Molecular Immunology. 81, p. 143-150 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A PITX3-EGFP Reporter Line Reveals Connectivity of Dopamine and Non-dopamine Neuronal Subtypes in Grafts Generated from Human Embryonic Stem Cells

Niclis, J. C., Gantner, C. W., Hunt, C. P. J., Kauhausen, J. A., Durnall, J. C., Haynes, J. M., Pouton, C. W., Parish, C. L. & Thompson, L. H., 12 Sep 2017, In : Stem Cell Reports. 9, 3, p. 868-882 15 p.

Research output: Contribution to journalArticleResearchpeer-review

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Assessing the impact of lithium chloride on the expression of P-glycoprotein at the blood-brain barrier

Newman, S. A., Pan, Y., Short, J. L. & Nicolazzo, J. A., Sep 2017, In : Journal of Pharmaceutical Sciences. 106, 9, p. 2625–2631 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A strategy to evaluate the surface energy of high packing efficiency fine powders via inverse gas chromatography

Tan, G., Qu, L., Morton, D. A. V. & Larson, I., 1 Oct 2017, In : Powder Technology. 320, p. 470-473 4 p.

Research output: Contribution to journalArticleResearchpeer-review

A suicidal strain of Listeria monocytogenes is effective as a DNA vaccine delivery system for oral administration

Sinha, S., Kuo, C. Y., Ho, J. K., White, P. J., Jazayeri, J. A. & Pouton, C. W., 2017, In : Vaccine. 35, 38, 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A traceless reversible polymeric colistin prodrug to combat multidrug-resistant (MDR) gram-negative bacteria

Zhu, C., Schneider, E. K., Wang, J., Kempe, K., Wilson, P., Velkov, T., Li, J., Davis, T., Whittaker, M. R. & Haddleton, D. M., 2017, In : Journal of Controlled Release. 259, 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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"Bottom-up" in situ proteomic differentiation of human and non-human haemoglobins for forensic purposes by matrix-assisted laser desorption/ionization time-of-flight tandem mass spectrometry

Kamanna, S., Henry, J., Voelcker, N., Linacre, A. & Kirkbride, K. P., 30 Nov 2017, In : Rapid Communications in Mass Spectrometry. 31, 22, p. 1927-1937 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Cationic acrylate oligomers comprising amino acid mimic moieties demonstrate improved antibacterial killing efficiency

Grace, J., Elliott, A. G., Huang, J. X., Schneider, E. K., Truong Phuoc, N., Cooper, M. A., Li, J., Davis, T., Quinn, J., Velkov, T. & Whittaker, M. R., 2017, In : Journal of Materials Chemistry B. 5, 3, p. 531-536 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of Solubilizing Nanoaggregates Present in Different Versions of Simulated Intestinal Fluid

Clulow, A. J., Parrow, A., Hawley, A., Khan, J., Pham, A. C., Larsson, P., Bergström, C. A. S. & Boyd, B. J., 7 Dec 2017, In : Journal of Physical Chemistry B. 121, 48, p. 10869-10881 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of the Polymyxin D Synthetase Biosynthetic Cluster and Product Profile of Paenibacillus polymyxa ATCC 10401

Galea, C. A., Han, M., Zhu, Y., Roberts, K., Wang, J., Thompson, P. E., Li, J. & Velkov, T., 26 May 2017, In : Journal of Natural Products. 80, 5, p. 1264-1274 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterizing the time-course of antihypertensive activity and optimal dose range of fimasartan via mechanism-based population modeling

Bulitta, J. B., Paik, S. H., Chi, Y. H., Kim, T. H., Shin, S., Landersdorfer, C. B., Jiao, Y., Yadav, R. & Shin, B. S., 30 Sep 2017, In : European Journal of Pharmaceutical Sciences. 107, p. 32-44 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Cofibrillization of Pathogenic and Functional Amyloid Proteins with Gold Nanoparticles against Amyloidogenesis

Javed, I., Sun, Y., Adamcik, J., Wang, B., Kakinen, A., Pilkington, E. H., Ding, F., Mezzenga, R., Davis, T. P. & Ke, P. C., 11 Dec 2017, In : Biomacromolecules. 18, 12, p. 4316-4322 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Comb poly(oligo(2-ethyl-2-oxazoline)methacrylate)-peptide conjugates prepared by aqueous Cu(0)-mediated polymerization and reductive amination

Collins, J., Wallis, S. J., Simula, A., Whittaker, M. R., McIntosh, M. P., Wilson, P., Davis, T. P., Haddleton, D. M. & Kempe, K., 1 Jan 2017, In : Macromolecular Rapid Communications. 38, 2, 7 p., 1600534.

Research output: Contribution to journalArticleResearchpeer-review

Comparison across Three Hybrid Lipid-Based Drug Delivery Systems for Improving the Oral Absorption of the Poorly Water-Soluble Weak Base Cinnarizine

Joyce, P., Yasmin, R., Bhatt, A., Boyd, B. J., Pham, A. & Prestidge, C. A., 6 Nov 2017, In : Molecular Pharmaceutics. 14, 11, p. 4008-4018 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Complex multiblock bottle-brush architectures by RAFT polymerization

Kerr, A., Hartlieb, M., Sanchis, J., Smith, T. & Perrier, S., 2017, In : Chemical Communications. 53, 87, p. 11901-11904 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids

Birru, W. A., Warren, D., Headey, S. J., Benameur, H., Porter, C., Pouton, C. W. & Chalmers, D. K., 6 Mar 2017, In : Molecular Pharmaceutics. 14, 3, p. 566-579 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Computational Models of the Intestinal Environment. 3. The Impact of Cholesterol Content and pH on Mixed Micelle Colloids

Suys, E. J. A., Warren, D. B., Porter, C. J. H., Benameur, H., Pouton, C. W. & Chalmers, D. K., 6 Nov 2017, In : Molecular Pharmaceutics. 14, 11, p. 3684-3697 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Copolyampholytes Produced from RAFT Polymerization of Protic Ionic Liquids

Fouillet, C. C. J., Greaves, T. L., Quinn, J. F., Davis, T. P., Adamcik, J., Sani, M. A., Separovic, F., Drummond, C. J. & Mezzenga, R., 28 Nov 2017, In : Macromolecules. 50, 22, p. 8965-8978 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Correlating in Vitro Solubilization and Supersaturation Profiles with in Vivo Exposure for Lipid Based Formulations of the CETP Inhibitor CP-532,623

McEvoy, C. L., Trevaskis, N. L., Feeney, O. M., Edwards, G. A., Perlman, M. E., Ambler, C. M. & Porter, C. J. H., 4 Dec 2017, In : Molecular Pharmaceutics. 14, 12, p. 4525-4538 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Curcumin attenuates colistin-induced neurotoxicity in N2a cells via anti-inflammatory activity, suppression of oxidative stress, and apoptosis

Dai, C., Ciccotosto, G. D., Cappai, R., Tang, S., Li, D., Xie, S., Xiao, X. & Velkov, T., 2017, (Accepted/In press) In : Molecular Neurobiology. p. 1-14 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Design and evaluation of novel polymyxin fluorescent probes

Yun, B., Roberts, K. D., Thompson, P. E., Nation, R. L., Velkov, T. & Li, J., 11 Nov 2017, In : Sensors. 17, 11, 8 p., 2598.

Research output: Contribution to journalArticleResearchpeer-review

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Development of a Gemcitabine-Polymer Conjugate with Prolonged Cytotoxicity against a Pancreatic Cancer Cell Line

Joubert, F., Martin, L., Perrier, S. & Pasparakis, G., 16 May 2017, In : ACS Macro Letters. 6, 5, p. 535-540 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Development of flexible supercapacitors using an inexpensive graphene/PEDOT/MnO2 sponge composite

Moussa, M., Shi, G., Wu, H., Zhao, Z., Voelcker, N. H., Losic, D. & Ma, J., 5 Jul 2017, In : Materials & Design. 125, p. 1-10 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential effects of silver and iron oxide nanoparticles on IAPP amyloid aggregation

Wang, M., Kakinen, A., Pilkington, E. H., Davis, T. P. & Ke, P-C., 1 Mar 2017, In : Biomaterials Science. 5, 3, p. 485-493 9 p.

Research output: Contribution to journalArticleResearchpeer-review

DNA-based probes for flow cytometry analysis of endocytosis and recycling

Dumont, C. F. M., Czuba, E., Chen, M., Villadangos, J. A., Johnston, A. P. R. & Mintern, J. D., 1 Apr 2017, In : Traffic. 18, 4, p. 242-249 8 p.

Research output: Contribution to journalArticleResearchpeer-review

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Dosing guidance for intravenous colistin in critically ill patients

Nation, R. L., Garonzik, S. M., Thamlikitkul, V., Giamarellos-Bourboulis, E. J., Forrest, A., Paterson, D. L., Li, J. & Silveira, F. P., 2017, In : Clinical Infectious Diseases. 64, 5, p. 565-571 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Dual-action cancer therapy with targeted porous silicon nanovectors

Cifuentes Rius, A., Ivask, A., Sporleder, E., Kaur, I., Assan, Y., Rao, S., Warther, D., Prestidge, C. A., Durand, J-O. & Voelcker, N., 4 Aug 2017, In : Small. 13, 29, 6 p., 1701201.

Research output: Contribution to journalArticleResearchpeer-review

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Dynamic formation of nanostructured particles from vesicles via invertase hydrolysis for on-demand delivery

Fong, W-K., Sánchez-Ferrer, A., Ortelli, F. G., Sun, W., Boyd, B. J. & Mezzenga, R., 2017, In : RSC Advances. 7, 8, p. 4368-4377 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers

Haque, S., McLeod, V. M., Jones, S., Fung, S., Whittaker, M., McIntosh, M., Pouton, C., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Oct 2017, In : European Journal of Pharmaceutics and Biopharmaceutics. 119, p. 408-418 11 p.

Research output: Contribution to journalArticleResearchpeer-review