Research Output 1975 2019

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2018
4 Citations (Scopus)

Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations

Williams, H. D., Ford, L., Han, S., Tangso, K. J., Lim, S., Shackleford, D. M., Vodak, D. T., Benameur, H., Pouton, C. W., Scammells, P. J. & Porter, C. J. H., 1 Jan 2018, In : Molecular Pharmaceutics. 15, 12, p. 5678−5696 19 p.

Research output: Contribution to journalArticleResearchpeer-review

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4 Citations (Scopus)

Experimental study of the deformation and breakage of 3D printed agglomerates: Effects of packing density and inter-particle bond strength

Ge, R., Ghadiri, M., Bonakdar, T., Zhou, Z., Larson, I. & Hapgood, K., 1 Dec 2018, In : Powder Technology. 340, p. 299-310 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Exploiting macromolecular design to optimize the antibacterial activity of alkylated cationic oligomers

Grace, J. L., Schneider-Futschik, E. K., Elliott, A. G., Amado, M., Truong, N. P., Cooper, M. A., Li, J., Davis, T. P., Quinn, J. F., Velkov, T. & Whittaker, M. R., 10 Dec 2018, In : Biomacromolecules. 19, 12, p. 4629-4640 12 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Fatty Acid-Binding Protein 5 Mediates the Uptake of Fatty Acids, but not Drugs, Into Human Brain Endothelial Cells

Lee, G. S., Pan, Y., Scanlon, M. J., Porter, C. J. H. & Nicolazzo, J. A., Apr 2018, In : Journal of Pharmaceutical Sciences. 107, 4, p. 1185-1193 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers

Jiao, Y., Kim, T. H., Tao, X., Kinzig, M., Landersdorfer, C. B., Drescher, S. K., Sutaria, D. S., Moya, B., Holzgrabe, U., Sörgel, F. & Bulitta, J. B., 15 Oct 2018, In : European Journal of Pharmaceutical Sciences. 123, p. 416-428 13 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Functional hydrophobic and hetero-grafted block comb polymers: Via a combination of spontaneous zwitterionic copolymerisation and redox-initiated RAFT polymerisation

Mahmoud, A. M., Rajakanthan, A. & Kempe, K., 7 Apr 2018, In : Polymer Chemistry. 9, 13, p. 1562-1566 5 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug Delivery

Ma, Y., Björnmalm, M., Wise, A. K., Cortez-Jugo, C., Revalor, E., Ju, Y., Feeney, O. M., Richardson, R. T., Hanssen, E., Shepherd, R. K., Porter, C. J. H. & Caruso, F., 19 Sep 2018, In : ACS Applied Materials and Interfaces. 10, 37, p. 31019-31031 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Genome-scale metabolic modeling of responses to polymyxins in Pseudomonas aeruginosa

Zhu, Y., Czauderna, T., Zhao, J., Klapperstueck, M., Mahamad Maifiah, M. H. B., Han, M-L., Lu, J., Sommer, B., Velkov, T., Lithgow, T., Song, J., Schreiber, F. & Li, J., 1 Apr 2018, In : GigaScience. 7, 4, 18 p., giy021.

Research output: Contribution to journalArticleResearchpeer-review

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10 Citations (Scopus)

Graphene quantum dots against human IAPP aggregation and toxicity in vivo

Wang, M., Sun, Y., Cao, X., Peng, G., Javed, I., Kakinen, A., Davis, T. P., Lin, S., Liu, J., Ding, F. & Ke, P. C., 14 Nov 2018, In : Nanoscale. 10, 42, p. 19995-20006 12 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

High-Throughput Assessment and Modeling of a Polymer Library Regulating Human Dental Pulp-Derived Stem Cell Behavior

Rasi Ghaemi, S., Delalat, B., Gronthos, S., Alexander, M. R., Winkler, D. A., Hook, A. L. & Voelcker, N. H., 14 Nov 2018, In : ACS Applied Materials and Interfaces. 10, 45, p. 38739-38748 10 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Human plasma proteome association and cytotoxicity of nano-graphene oxide grafted with stealth polyethylene glycol and poly(2-ethyl-2-oxazoline)

Wang, M., Gustafsson, O. J. R., Siddiqui, G., Javed, I., Kelly, H. G., Blin, T., Yin, H., Kent, S. J., Creek, D. J., Kempe, K., Ke, P. C. & Davis, T. P., 21 Jun 2018, In : Nanoscale. 10, 23, p. 10863-10875 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Hyaluronic Acid-Modified Porous Silicon Films for the Electrochemical Sensing of Bacterial Hyaluronidase

Tücking, K. S., Vasani, R. B., Cavallaro, A. A., Voelcker, N. H., Schönherr, H. & Prieto-Simon, B., Oct 2018, In : Macromolecular Rapid Communications. 39, 19, 7 p., 1800178.

Research output: Contribution to journalArticleResearchpeer-review

Identification and In Vitro Expansion of Buccal Epithelial Cells

Ghaemi, S. R., Delalat, B., Harding, F. J., Irani, Y. D., Williams, K. A. & Voelcker, N. H., 1 Jun 2018, In : Cell Transplantation. 27, 6, p. 957-966 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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1 Citation (Scopus)

Imaging Proton Transport in Giant Vesicles through Cyclic Peptide–Polymer Conjugate Nanotube Transmembrane Ion Channels

Binfield, J. G., Brendel, J. C., Cameron, N. R., Eissa, A. M. & Perrier, S., 1 Oct 2018, In : Macromolecular Rapid Communications. 39, 19, 6 p., 1700831.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Impact of aging, Alzheimer's disease and Parkinson's disease on the blood-brain barrier transport of therapeutics

Pan, Y. & Nicolazzo, J. A., Oct 2018, In : Advanced Drug Delivery Reviews. 135, p. 62-74 13 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations

Alskär, L. C., Keemink, J., Johannesson, J., Porter, C. J. H. & Bergström, C. A. S., 1 Oct 2018, In : Molecular Pharmaceutics. 15, 10, p. 4733-4744 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Induced pluripotent stem cell-derived podocyte-like cells as models for assessing mechanisms underlying heritable disease phenotype: Initial studies using two alport syndrome patient lines indicate impaired potassium channel activity

Haynes, J. M., Selby, J. N., Vandekolk, T. H., Abad, I. P. L., Ho, J. K., Lieuw, W-L., Leach, K., Savige, J., Saini, S., Fisher, C. L. & Ricardo, S. D., 1 Nov 2018, In : Journal of Pharmacology and Experimental Therapeutics. 367, 2, p. 335-347 13 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Induction of vaginal-resident HIV-specific CD8 T cells with mucosal prime-boost immunization

Tan, H. X., Wheatley, A. K., Esterbauer, R., Jegaskanda, S., Glass, J. J., Masopust, D., De Rose, R. & Kent, S. J., 1 May 2018, In : Mucosal Immunology. 11, 3, p. 994-1007 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Influence of charge on hemocompatibility and immunoreactivity of polymeric nanoparticles

Chen, L., Glass, J. J., De Rose, R., Sperling, C., Kent, S. J., Houston, Z. H., Fletcher, N. L., Rolfe, B. E. & Thurecht, K. J., Sep 2018, In : ACS Applied Bio Materials. 1, 3, p. 756-767 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Interactions of artefenomel (OZ-439) with milk during digestion: insights into digestion-driven solubilization and polymorphic transformations

Salim, M., Khan, J., Ramirez, G., Clulow, A. J., Hawley, A., Ramachandruni, H. & Boyd, B. J., 22 Jun 2018, In : Molecular Pharmaceutics. 15, 8, p. 3535-3544 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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10 Citations (Scopus)

In Vivo Mitigation of Amyloidogenesis through Functional-Pathogenic Double-Protein Coronae

Javed, I., Yu, T., Peng, G., Sánchez-Ferrer, A., Faridi, A., Kakinen, A., Zhao, M., Mezzenga, R., Davis, T. P., Lin, S. & Ke, P. C., 12 Sep 2018, In : Nano Letters. 18, 9, p. 5797-5804 8 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Ionophore and Biometal Modulation of P-glycoprotein Expression and Function in Human Brain Microvascular Endothelial Cells

McInerney, M. P., Volitakis, I., Bush, A. I., Banks, W. A., Short, J. L. & Nicolazzo, J. A., 1 Apr 2018, In : Pharmaceutical Research. 35, 4, 12 p., 83.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

Journey to the centre of the cell: Virtual reality immersion into scientific data

Johnston, A. P. R., Rae, J., Ariotti, N., Bailey, B., Lilja, A., Webb, R., Ferguson, C., Maher, S., Davis, T. P., Webb, R. I., McGhee, J. & Parton, R. G., 1 Feb 2018, In : Traffic. 19, 2, p. 105-110 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Knowledge, perception and practice towards oxytocin stability and quality: A qualitative study of stakeholders in three resourcelimited countries

Oliver, V. L., Lambert, P. A., Than, K. K., Mohamed, Y., Luchters, S., Verma, S., Yadav, R., Kumar, V., Teklu, A. M., Tolera, M., Minaye, A. & McIntosh, M. P., 1 Sep 2018, In : PLoS ONE. 13, 9, e0203810.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Large Hexosomes from Emulsion Droplets: Particle Shape and Mesostructure Control

Wang, H., Zetterlund, P. B., Boyer, C., Boyd, B. J., Atherton, T. J. & Spicer, P. T., 15 Oct 2018, In : Langmuir. 34, 45, p. 13662-13671 10 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD)

Montagnat, O. D., Webster, G. R., Bulitta, J. B., Landersdorfer, C., Wyber, R., Sheel, M., Carapetis, J. R. & Boyd, B. J., 5 Feb 2018, In : Drug Delivery and Translational Research. 8, 3, p. 729-739 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Linker chemistry dictates the delivery of a phototoxic organometallic rhenium(i) complex to human cervical cancer cells from core crosslinked star polymer nanoparticles

Yu, S. H., Patra, M., Ferrari, S., Ramirez Garcia, P., Veldhuis, N. A., Kaminskas, L. M., Graham, B., Quinn, J. F., Whittaker, M. R., Gasser, G. & Davis, T. P., 29 Oct 2018, In : Journal of Materials Chemistry B. 6, 47, p. 7805-7810 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Lipidomic analysis of the outer membrane vesicles from paired polymyxin-susceptible and -resistant Klebsiella pneumoniae clinical isolates

Jasim, R., Han, M-L., Zhu, Y., Hu, X., Hussein, M. H., Lin, Y-W., Zhou, T. Q., Dong, C. Y. D., Li, J. & Velkov, T., 10 Aug 2018, In : International Journal of Molecular Sciences. 19, 8, 13 p., 2356.

Research output: Contribution to journalArticleResearchpeer-review

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2 Citations (Scopus)

Macrocyclic Side-Chain Monomers for Photoinduced ATRP: Synthesis and Properties versus Long-Chain Linear Isomers

Barbon, S. M., Rolland, M., Anastasaki, A., Truong, N. P., Schulze, M. W., Bates, C. M. & Hawker, C. J., 11 Sep 2018, In : Macromolecules. 51, 17, p. 6901-6910 10 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Magnetic nanoparticles coated with a thermosensitive polymer with hyperthermia properties

Reyes-Ortega, F., Delgado, Á. V., Schneider, E. K., Checa Fernández, B. L. & Iglesias, G. R., 2018, In : Polymers. 10, 1, 15 p., 10.

Research output: Contribution to journalArticleResearchpeer-review

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6 Citations (Scopus)

Manipulating human dendritic cell phenotype and function with targeted porous silicon nanoparticles

Stead, S. O., McInnes, S. J. P., Kireta, S., Rose, P. D., Jesudason, S., Rojas-Canales, D., Warther, D., Cunin, F., Durand, J. O., Drogemuller, C. J., Carroll, R. P., Coates, P. T. & Voelcker, N. H., 1 Feb 2018, In : Biomaterials. 155, p. 92-102 11 p.

Research output: Contribution to journalArticleResearchpeer-review

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3 Citations (Scopus)

Mechanism-based pharmacokinetic/pharmacodynamic modeling of aerosolized colistin in a mouse lung infection model

Lin, Y-W., Zhou, Q. T., Han, M-L., Onufrak, N. J., Chen, K., Wang, J., Forrest, A., Chan, H-K. & Li, J., 1 Mar 2018, In : Antimicrobial Agents and Chemotherapy. 62, 3, 14 p., e01965-17.

Research output: Contribution to journalArticleResearchpeer-review

Mechanistic Insights From Global Metabolomics Studies into Synergistic Bactericidal Effect of a Polymyxin B Combination With Tamoxifen Against Cystic Fibrosis MDR Pseudomonas aeruginosa

Hussein, M., Han, M-L., Zhu, Y., Schneider-Futschik, E. K., Hu, X., Zhou, Q. T., Lin, Y-W., Anderson, D., Creek, D. J., Hoyer, D., Li, J. & Velkov, T., 1 Jan 2018, In : Computational and Structural Biotechnology Journal. 16, p. 587-599 13 p.

Research output: Contribution to journalArticleResearchpeer-review

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3 Citations (Scopus)

Meropenem Combined with Ciprofloxacin Combats Hypermutable Pseudomonas aeruginosa from Respiratory Infections of Cystic Fibrosis Patients

Rees, V. E., Yadav, R., Rogers, K. E., Bulitta, J. B., Wirth, V., Oliver, A., Boyce, J. D., Peleg, A. Y., Nation, R. L. & Landersdorfer, C. B., 1 Nov 2018, In : Antimicrobial Agents and Chemotherapy. 62, 11, 12 p., e01150-18.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Metabolic Analyses Revealed Time-Dependent Synergistic Killing by Colistin and Aztreonam Combination Against Multidrug-Resistant Acinetobacter baumannii

Han, M-L., Liu, X., Velkov, T., Lin, Y-W., Zhu, Y., Li, M., Yu, H. H., Zhou, Z., Creek, D. J., Zhang, J. & Li, J., 16 Nov 2018, In : Frontiers in Microbiology. 9, 12 p., 2776.

Research output: Contribution to journalArticleResearchpeer-review

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7 Citations (Scopus)

Methionine ameliorates polymyxin-induced nephrotoxicity by attenuating cellular oxidative stress

Azad, M. A. K., Sivanesan, S., Wang, J., Chen, K., Nation, R. L., Thompson, P. E., Roberts, K. D., Velkov, T. & Li, J., 1 Jan 2018, In : Antimicrobial Agents and Chemotherapy. 62, 1, 9 p., e01254.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Micelle directed chemical polymerization of polypyrrole particles for the electrically triggered release of dexamethasone base and dexamethasone phosphate

Uppalapati, D., Sharma, M., Aqrawe, Z., Coutinho, F., Rupenthal, I. D., Boyd, B. J., Travas-Sejdic, J. & Svirskis, D., 30 May 2018, In : International Journal of Pharmaceutics. 543, 1-2, p. 38-45 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Microengineered Bioartificial Liver Chip for Drug Toxicity Screening

Delalat, B., Cozzi, C., Rasi Ghaemi, S., Polito, G., Kriel, F. H., Michl, T. D., Harding, F. J., Priest, C., Barillaro, G. & Voelcker, N. H., 11 Jul 2018, In : Advanced Functional Materials. 28, 28, 10 p., 1801825.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Microfluidic Cell Microarray Platform for High Throughput Analysis of Particle-Cell Interactions

Tong, Z., Rajeev, G., Guo, K., Ivask, A., McCormick, S., Lombi, E., Priest, C. & Voelcker, N. H., 3 Apr 2018, In : Analytical Chemistry. 90, 7, p. 4338-4347 10 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Microfluidic Examination of the "hard" Biomolecular Corona Formed on Engineered Particles in Different Biological Milieu

Weiss, A. C. G., Kempe, K., Förster, S. & Caruso, F., 9 Jul 2018, In : Biomacromolecules. 19, 7, p. 2580-2594 15 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Microfluidic Mass Production of Stabilized and Stealthy Liquid Metal Nanoparticles

Tang, S. Y., Qiao, R., Yan, S., Yuan, D., Zhao, Q., Yun, G., Davis, T. P. & Li, W., 24 May 2018, In : Small. 14, 21, 8 p., 1800118.

Research output: Contribution to journalArticleResearchpeer-review

59 Citations (Scopus)

Minimum information reporting in bio–nano experimental literature

Faria, M., Björnmalm, M., Thurecht, K. J., Kent, S. J., Parton, R. G., Kavallaris, M., Johnston, A. P. R., Gooding, J. J., Corrie, S. R., Boyd, B. J., Thordarson, P., Whittaker, A. K., Stevens, M. M., Prestidge, C. A., Porter, C. J. H., Parak, W. J., Davis, T. P., Crampin, E. J. & Caruso, F., 1 Sep 2018, In : Nature Nanotechnology. 13, 9, p. 777-785 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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10 Citations (Scopus)

Mitigating Human IAPP Amyloidogenesis In Vivo with Chiral Silica Nanoribbons

Faridi, A., Sun, Y., Okazaki, Y., Peng, G., Gao, J., Kakinen, A., Faridi, P., Zhao, M., Javed, I., Purcell, A. W., Davis, T. P., Lin, S., Oda, R., Ding, F. & Ke, P. C., 22 Nov 2018, In : Small. 14, 47, 13 p., 1802825.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Mitochondrial imaging in live or fixed tissues using a luminescent iridium complex

Sorvina, A., Bader, C. A., Darby, J. R. T., Lock, M. C., Soo, J. Y., Johnson, I. R. D., Caporale, C., Voelcker, N. H., Stagni, S., Massi, M., Morrison, J. L., Plush, S. E. & Brooks, D. A., 1 Dec 2018, In : Scientific Reports. 8, 1, 8 p., 8191.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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4 Citations (Scopus)

Murine and Non-Human Primate Dendritic Cell Targeting Nanoparticles for in Vivo Generation of Regulatory T-Cells

Stead, S. O., Kireta, S., McInnes, S. J. P., Kette, F. D., Sivanathan, K. N., Kim, J., Cueto-Diaz, E. J., Cunin, F., Durand, J. O., Drogemuller, C. J., Carroll, R. P., Voelcker, N. H. & Coates, P. T., 24 Jul 2018, In : ACS Nano. 12, 7, p. 6637-6647 11 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Mutations in the pantothenate kinase of Plasmodium falciparum confer diverse sensitivity profiles to antiplasmodial pantothenate analogues

Tjhin, E. T., Spry, C., Sewell, A. L., Hoegl, A., Barnard, L., Sexton, A. E., Siddiqui, G., Howieson, V. M., Maier, A. G., Creek, D. J., Strauss, E., Marquez, R., Auclair, K. & Saliba, K. J., 1 Apr 2018, In : PLoS Pathogens. 14, 4, 30 p., e1006918.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

Nano-assemblies of cationic mPEG brush block copolymers with gadolinium polyoxotungstate [Gd(W5O18)2]9- form stable, high relaxivity MRI contrast agents

Ly, J., Li, Y., Vu, M. N., Moffat, B. A., Jack, K. S., Quinn, J. F., Whittaker, M. R. & Davis, T. P., 21 Apr 2018, In : Nanoscale. 10, 15, p. 7270-7280 11 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Nanoscale inhibition of polymorphic and ambidextrous IAPP amyloid aggregation with small molecules

Kakinen, A., Adamcik, J., Wang, B., Ge, X., Mezzenga, R., Davis, T. P., Ding, F. & Ke, P. C., Jul 2018, In : Nano Research. 11, 7, p. 3636-3647 12 p.

Research output: Contribution to journalArticleResearchpeer-review