Research Output

Filter
Article

Drug delivery: A key factor in realising the full therapeutic potential of drugs

Charman, W. N., Chan, H-K., Finnin, B. C. & Charman, S. A., 1999, In : Drug Development Research. 46, 3-4, p. 316-327 12 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Effect of cirrhosis on sulphation by the isolated perfused rat liver

Choo, E. F., Angus, P. W. & Morgan, D. J., 1999, In : Journal of Hepatology. p. 498 - 502 5 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Fetal hepatic drug elimination

Ring, J. A., Ghabrial, H., Ching, M. S., Smallwood, R. A. & Morgan, D. J., 1999, In : Pharmacology and Therapeutics. p. 429 - 445 17 p.

Research output: Contribution to journalArticleResearchpeer-review

92 Citations (Scopus)

Gene transfer using a bifunctional peptide

Nwachuku, J. N., Ashford, M. & Pouton, C. W., 1 Jan 1999, In : Proceedings of the Controlled Release Society. 26, p. 531-532 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Hepatic disposition of the acyl glucuronide 1-O-gemfibrozil-β-D- glucuronide: Effects of dibromosulfophthalein on membrane transport and aglycone formation

Sabordo, L., Sallustio, B. C., Evans, A. M. & Nation, R. L., 1 Feb 1999, In : Journal of Pharmacology and Experimental Therapeutics. 288, 2, p. 414-420 7 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Mechanisms controlling diffusion and release of model proteins through and from partially esterified hyaluronic acid membranes

Simon, L. D., Stella, V. J., Charman, W. N. & Charman, S. A., 20 Sep 1999, In : Journal of Controlled Release. 61, 3, p. 267-279 13 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Organ perfusion techniques in drug development

Stretch, G. L., Nation, R. L., Evans, A. M. & Milne, R. W., 14 Jun 1999, In : Drug Development Research. 46, 3-4, p. 292-301 10 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Synthesis of porphyrin alpha,omega-bis(methylamino)peptide constructs: New Journal of Chemistry

Matthews, S. E., Pouton, C. W. & Threadgill, M. D., 1999, In : New Journal of Chemistry. 23, p. 1087-1096 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis of porphyrin α,ω-bis(methylamino)peptide constructs

Matthews, S. E., Pouton, C. W. & Threadgill, M. D., 1 Jan 1999, In : New Journal of Chemistry. 23, 11, p. 1087-1096 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Transdermal penetration enhancers: Applications, limitations, and potential

Finnin, B. C. & Morgan, T. M., 1999, In : Journal of Pharmaceutical Sciences. p. 955 - 958 4 p.

Research output: Contribution to journalArticleResearchpeer-review

208 Citations (Scopus)

Uptake and excretion of sodium taurocholate by the isolated perfused neonatal sheep liver

Gow, P. J., Treepongkaruna, S., Ching, M. S., Ghabrial, H., Shulkes, A., Smallwood, R. A. & Morgan, D. J., 1999, In : Journal of Pharmaceutical Sciences. p. 445 - 449 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Variation in the diffusion and release of ribonuclease through and from esterified hyaluronic acid membranes: Effect of changes in matrix characteristics

Simon, L. D., Stella, V. J., Charman, W. N. & Charman, S. A., 27 Aug 1999, In : Journal of Controlled Release. 61, 1-2, p. 159-164 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1998

Analytical methods and stability assessment of liquid yeast derived sucrase

McIntosh, K. A., Charman, S. A., Borgen, L. A. & Charman, W. N., 1998, In : Journal of Pharmaceutical and Biomedical Analysis. p. 1037 - 1045 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A priming dose of propranolol reduces the availability of a subsequent dose in the isolated perfused rat liver preparation

Ghabrial, H., Sewell, R. B., Smallwood, R. A. & Morgan, D. J., 1998, In : Clinical and Experimental Pharmacology and Physiology. p. 110 - 113 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state

Humberstone, A. J., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 1998, In : Journal of Pharmaceutical Sciences. p. 936 - 942 7 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

Asthma medications, equipment supplied and sources of information for Australian community pharmacists

Gattera, J. A., Abramson, M. J. & Roller, L., 1998, In : Australian Journal of Pharmacy. p. 840 - 848 9 p.

Research output: Contribution to journalArticleResearch

2 Citations (Scopus)

Compatibility of ketamine and morphine injections

Lau, M-H., Hackman, C. & Morgan, D. J., 1998, In : Pain. 75, p. 389 - 390 2 p.

Research output: Contribution to journalArticleOther

13 Citations (Scopus)

Computer-based course for foreign pharmacists seeking registration in Australia

Pappas, A., Stewart, K., Roller, L., Reed, B. L., Cesnik, B., Hoffman, J. & Sorgetti, L., 1998, In : Pharmaceutical Journal. p. 586 - 587 2 p.

Research output: Contribution to journalArticleOther

Computer-based courses for foreign pharmacists seeking registration in Australia

Pappas, A., Stewart, K., Roller, L., Reed, B. L., Cesnik, B., Hoffman, J. & Sorgetti, L., 1998, In : Pharmaceutical Journal. p. 586 - 587 2 p.

Research output: Contribution to journalArticleOther

Deaggregation during the dissolution of benzodiazepines in interactive mixtures

Liu, J. & Stewart, P. J., 1998, In : Journal of Pharmaceutical Sciences. p. 1632 - 1638 7 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Degradation of recombinant porcine growth hormone in the presence of guanidine hydrochloride

McCrossin, L. E., Charman, W. N. & Charman, S. A., 30 Oct 1998, In : International Journal of Pharmaceutics. 173, 1-2, p. 157-170 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Drug-induced liver disease

Morgan, D. J., 1998, In : Current Practice in Medicine. p. 68 - 70 3 p.

Research output: Contribution to journalArticleOther

Effect of alterd serum lipid concentrations on the IC50 of Halofantrine against Plasmodium Falciparum

Humberstone, A. J., Cowman, A. F., Horton, J. & Charman, W. N., 1998, In : Journal of Pharmaceutical Sciences. p. 256 - 258 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of altered serum lipid concentrations on the IC50 of halofantrine against Plasmodium Falciparum

Humberstone, A. J., Cowman, A. F., Horton, J. & Charman, W. N., 1 Jan 1998, In : Journal of Pharmaceutical Sciences. 87, 2, p. 256-258 3 p.

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)

Effect of cationic drugs on the renal secretion of ranitidine in the rat isolated perfused kidney

Nation, R. L., Evans, A. M., Cabot, J. L., Shanahan, K. M. & Hsyu, P. H., 1 Jan 1998, In : Clinical and Experimental Pharmacology and Physiology. 25, 1, p. 33-37 5 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Effect of filgrastim on the pharmacokinetics of MX2 hydrochloride in patients with advanced malignant disease

Morgan, D. J., Hill, J. S., Clarke, K., Stylli, S. S., Park, S. J., Cebon, J., Basser, R. L., Kaye, A. H., Geldard, H., Maher, D. W. & Green, M. D., 1998, In : Cancer Chemotherapy and Pharmacology. p. 423 - 426 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Enhanced skin permeation of sex hormones with novel topical spray vehicles

Morgan, T. M., Reed, B. L. & Finnin, B. C., 1998, In : Journal of Pharmaceutical Sciences. p. 1213 - 1218 6 p.

Research output: Contribution to journalArticleResearchpeer-review

71 Citations (Scopus)

Enhanced transdermal delivery of sex hormones in swine with a novel topical aerosol

Morgan, T. M., Parr, R. A., Reed, B. L. & Finnin, B. C., 1998, In : Journal of Pharmaceutical Sciences. p. 1219 - 1225 7 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)

Evaluation of a computer-based bridging course by overseas-qualified pharmacists seeking Australian registration

Pappas, A., Stewart, K., Cesnik, B., Reed, B. L., Roller, L., Hoffman, J. & Sorgetti, L., 1998, In : American Journal of Pharmaceutical Education. p. 315 - 323 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine

Khoo, S-M., Humberstone, A. J., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 1998, In : International Journal of Pharmaceutics. p. 155 - 164 10 p.

Research output: Contribution to journalArticleResearchpeer-review

333 Citations (Scopus)

Glucuronidation of dihydrocodeine by human liver microsomes and the effect of inhibitors

Kirkwood, L. C., Nation, R. L. & Somogyi, A. A., 1 Jan 1998, In : Clinical and Experimental Pharmacology and Physiology. 25, 3-4, p. 266-270 5 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Key issues in non-viral gene delivery: Adv Drug Deliv Rev

Pouton, C. W. & Seymour, L. W., 1998, In : Advanced Drug Delivery Reviews. 34, p. 3-19 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Knowledge of asthma symptoms, preventer medications and asthma counselling practices of Australian community pharmacists

Gattera, J. A., Abramson, M. J. & Roller, L., 1998, In : Australian Journal of Pharmacy. p. 976 - 982 7 p.

Research output: Contribution to journalArticleOther

5 Citations (Scopus)

Metabolism of halofantrine to its equipotent metabolite, desbutylhalofantrine, is decreased when orally administered with ketoconazole

Khoo, S-M., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 1998, In : Journal of Pharmaceutical Sciences. p. 1538 - 1541 4 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Myocardial effect compartment modeling of metoprolol and sotalol: Importance of myocardial subsite drug concentration

Ritchie, R. H., Morgan, D. J. & Horowitz, J. D., 1998, In : Journal of Pharmaceutical Sciences. p. 177 - 182 6 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Nuclear import of polypeptides, polynucleotides and supramolecular complexes: Adv Drug Deliv Rev

Pouton, C. W., 1998, In : Advanced Drug Delivery Reviews. 34, p. 51-64 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Phase I and pharmacokinetic study of KRN8602 alone and with filgrastim in patients with advanced cancer

Clarke, K., Basser, R. L., Maher, D. W., Morgan, D. J., Cebon, J., Fox, R. M., Hill, J. S., Alt, C., Bartlett, J., Geldard, H., Kaye, A. H. & Green, M. D., 1998, In : Journal of Clinical Oncology. p. 2181 - 2187 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Polycation-DNA complexes for gene delivery: A comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids

Pouton, C. W., Lucas, P., Thomas, B. J., Uduehi, A. N., Milroy, D. A. & Moss, S. H., 30 Apr 1998, In : Journal of Controlled Release. 53, 1-3, p. 289-299 11 p.

Research output: Contribution to journalArticleResearchpeer-review

229 Citations (Scopus)

Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids: J Control Release

Pouton, C. W., Lucas, P., Thomas, B. J., Uduehi, A. N., Milroy, D. A. & Moss, S. H., 1998, In : Journal of Controlled Release. 53, p. 289-299 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Propranolol elimination by right and left fetal liver: Studies in the intact isolated perfused fetal sheep liver

Ring, J. A., Ghabrial, H., Ching, M. S., Shulkes, A., Smallwood, R. A. & Morgan, D. J., 1998, In : Journal of Pharmacology and Experimental Therapeutics. p. 535 - 541 7 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Relationships among liver and kidney volumes, lean body mass and drug clearance

Narawatne, S., Brien, J-A. E., Seeman, E., Fabiny, R., Zalcberg, J. R., Cosolo, W., Angus, P. W. & Morgan, D. J., 1998, In : British Journal of Clinical Pharmacology. p. 447 - 452 6 p.

Research output: Contribution to journalArticleResearchpeer-review

44 Citations (Scopus)

The application of capillary electrophoresis for monitoring effects of excipients on protein conformation

McIntosh, K. A., Charman, W. N. & Charman, S. A., Feb 1998, In : Journal of Pharmaceutical and Biomedical Analysis. 16, 6, p. 1097-1105 9 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

Theme title: Transport of macromolecules and viruses - Preface: Advanced Drug Delivery Reviews

Pouton, C. & Seymour, L. W., 1998, In : Advanced Drug Delivery Reviews. 34, p. 1-2 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Transdermal delivery of estradiol in postmenopausal women with a novel topical aerosol

Morgan, T. M., O'Sullivan, H. M. M., Reed, B. L. & Finnin, B. C., 1998, In : Journal of Pharmaceutical Sciences. p. 1226 - 1228 3 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)
1997

Accuracy of volume measurement using helical CT

Nawaratne, S., Fabiny, R., Brien, J-A. E., Zalcberg, J. R., Cosolo, W., Whan, A. & Morgan, D. J., 1997, In : Journal of Computer Assisted Tomography. p. 481 - 486 6 p.

Research output: Contribution to journalArticleResearchpeer-review

63 Citations (Scopus)

Characterization of the human cytochrome P450 enzymes involved in the metabolism of dihydrocodeine

Kirkwood, L. C., Nation, R. L. & Somogyi, A. A., 16 Dec 1997, In : British Journal of Clinical Pharmacology. 44, 6, p. 549-555 7 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Comparison of the disposition of hepatically-generated morphine-3-glucuronide and morphine-6-glucuronide in isolated perfused liver from the guinea pig

Milne, R. W., Jensen, R. H., Larsen, C., Evans, A. M. & Nation, R. L., 15 Sep 1997, In : Pharmaceutical Research. 14, 8, p. 1014-1018 5 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Concentration-effect relationships of morphine and morphine-6β- glucuronide in the rat

Van Crugten, J. T., Somogyi, A. A., Nation, R. L. & Reynolds, G., 9 Jun 1997, In : Clinical and Experimental Pharmacology and Physiology. 24, 5, p. 359-364 6 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Determination of the dihydrocodeine metabolites, dihydromorphine and nordihydrocodeine, in hepatic microsomal incubations by high-performance liquid chromatography

Kirkwood, L. C., Nation, R. L. & Somogyi, A. A., 7 Nov 1997, In : Journal of Chromatography B: Biomedical Applications. 701, 1, p. 129-134 6 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)