Research Output 1975 2019

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2019

Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)

Palmelund, H., Andersson, M. P., Asgreen, C. J., Boyd, B. J., Rantanen, J. & Löbmann, K., 1 Dec 2019, In : International Journal of Pharmaceutics: X. 1, p. 1-9 9 p., 100034.

Research output: Contribution to journalArticleResearchpeer-review

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Temperature stability of oxytocin ampoules labelled for storage at 2°C-8°C and below 25°C: an observational assessment under controlled accelerated and temperature cycling conditions

Nguyen, T-H., Lambert, P., Minhas, R. S., McEvoy, C., Deadman, K., Wright, P., Prankerd, R. J., Mogatle, S. & McIntosh, M. P., 26 Jul 2019, In : BMJ Open. 9, 7, p. 1-7 7 p., e029083.

Research output: Contribution to journalArticleResearchpeer-review

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The Development Process for Discovery and Clinical Advancement of Modern Antimalarials

Ashton, T. D., Devine, S., Mohrle, J., Laleu, B., Burrows, J. N., Charman, S., Creek, D. & Sleebs, B. E., Aug 2019, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The distribution of cell-penetrating peptides on polymeric nanoparticles prepared using microfluidics and elucidated with small angle X-ray scattering

Streck, S., Clulow, A. J., Nielsen, H. M., Rades, T., Boyd, B. J. & McDowell, A., 1 Nov 2019, In : Journal of Colloid and Interface Science. 555, p. 438-448 11 p.

Research output: Contribution to journalArticleResearchpeer-review

The Effects of Clioquinol on P-glycoprotein Expression and Biometal Distribution in the Mouse Brain Microvasculature

McInerney, M. P., Pan, Y., Volitakis, I., Bush, A. I., Short, J. L. & Nicolazzo, J. A., Dec 2019, In : Journal of Pharmaceutical Sciences. 108, 7, p. 2247-2255 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

The mechanisms of pharmacokinetic food-drug interactions – A perspective from the UNGAP group

Koziolek, M., Alcaro, S., Augustijns, P., Basit, A. W., Grimm, M., Hens, B., Hoad, C. L., Jedamzik, P., Madla, C. M., Maliepaard, M., Marciani, L., Maruca, A., Parrott, N., Pávek, P., Porter, C. J. H., Reppas, C., van Riet-Nales, D., Rubbens, J., Statelova, M., Trevaskis, N. L. & 4 others, Valentová, K., Vertzoni, M., Čepo, D. V. & Corsetti, M., 15 Jun 2019, In : European Journal of Pharmaceutical Sciences. 134, p. 31-59 29 p.

Research output: Contribution to journalArticleResearchpeer-review

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1 Citation (Scopus)

Thinking about critical thinking: An industry perspective

Pearl, A. O., Rayner, G. M., Larson, I. & Orlando, L., 2019, In : Industry and Higher Education. 33, 2, p. 116-126 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Tuning the Structure, Stability, and Responsivity of Polymeric Arsenical Nanoparticles Using Polythiol Cross-Linkers

Tanaka, J., Moriceau, G., Cook, A., Kerr, A., Zhang, J., Peltier, R., Perrier, S., Davis, T. P. & Wilson, P., 12 Feb 2019, In : Macromolecules. 52, 3, p. 992-1003 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Understanding the Impacts of Surface Compositions on the In-Vitro Dissolution and Aerosolization of Co-Spray-Dried Composite Powder Formulations for Inhalation

Mangal, S., Xu, R., Park, H., Zemlyanov, D., Shetty, N., Lin, Y-W., Morton, D., Chan, H-K., Li, J. & Zhou, T. Q., 1 Jan 2019, In : Pharmaceutical Research. 36, 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Understanding the kinetic mixing between liquid crystalline nanoparticles and agrochemical actives

Bisset, N. B., Webster, G. R., Dong, Y. D. & Boyd, B. J., 1 Mar 2019, In : Colloids and Surfaces B: Biointerfaces. 175, p. 324-332 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Unlocking the full potential of lipid-based formulations using lipophilic salt/ionic liquid forms

Williams, H. D., Ford, L., Igonin, A., Shan, Z., Botti, P., Morgen, M. M., Hu, G., Pouton, C. W., Scammells, P. J., Porter, C. J. H. & Benameur, H., 2019, In : Advanced Drug Delivery Reviews. 142, 16 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Uptake, depuration and sublethal effects of the neonicotinoid, imidacloprid, exposure in Sydney rock oysters

Ewere, E. E., Powell, D., Rudd, D., Reichelt-Brushett, A., Mouatt, P., Voelcker, N. H. & Benkendorff, K., 1 Sep 2019, In : Chemosphere. 230, p. 1-13 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Utilization of 4-(trifluoromethyl)benzenesulfonates as Counter Ions Tunes the Initiator Efficiency of Sophisticated Initiators for the Preparation of Well-Defined poly(2-oxazoline)s

Engel, N., Dirauf, M., Seupel, S., Leiske, M. N., Schubert, S. & Schubert, U. S., 1 Jan 2019, In : Macromolecular Rapid Communications. 40, 12, 7 p., 1900094.

Research output: Contribution to journalArticleResearchpeer-review

Visible light-triggered cargo release from donor acceptor Stenhouse adduct (DASA)-doped lyotropic liquid crystalline nanoparticles

Jia, S., Tan, A., Hawley, A., Graham, B. & Boyd, B. J., 15 Jul 2019, In : Journal of Colloid and Interface Science. 548, p. 151-159 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2018
11 Citations (Scopus)

A closer look at the behaviour of milk lipids during digestion

Clulow, A. J., Salim, M., Hawley, A. & Boyd, B. J., 1 Mar 2018, In : Chemistry and Physics of Lipids. 211, p. 107-116 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A Comparative Study of Outer Membrane Proteome between Paired Colistin-Susceptible and Extremely Colistin-Resistant Klebsiella pneumoniae Strains

Jasim, R., Baker, M. A., Zhu, Y., Han, M., Schneider-Futschik, E. K., Hussein, M., Hoyer, D., Li, J. & Velkov, T., 2018, In : ACS Infectious Diseases. 4, 12, p. 1692-1704 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

A complementary forensic ‘proteo-genomic’ approach for the direct identification of biological fluid traces under fingernails

Kamanna, S., Henry, J., Voelcker, N., Linacre, A. & Paul Kirkbride, K., 1 Sep 2018, In : Analytical and Bioanalytical Chemistry. 410, 24, p. 6165-6175 11 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

Evans, M. A., Lim, R., Kim, H. A., Chu, H. X., Gardiner-Mann, C. V., Taylor, K. W. E., Chan, C. T., Brait, V. H., Lee, S., Dinh, Q. N., Vinh, A., Phan, T. G., Srikanth, V. K., Ma, H., Arumugam, T. V., Fann, D. Y., Poh, L., Hunt, C. P. J., Pouton, C. W., Haynes, J. M. & 12 others, Selemidis, S., Kwan, W., Teo, L., Bourne, J. A., Neumann, S., Young, S., Gowing, E. K., Drummond, G. R., Clarkson, A. N., Wallace, E. M., Sobey, C. G. & Broughton, B. R. S., 1 Mar 2018, In : Stroke. 49, 3, p. 700-709 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)
5 Citations (Scopus)

A high parasite density environment induces transcriptional changes and cell death in Plasmodium falciparum blood stages

Chou, E. S., Abidi, S. Z., Teye, M., Leliwa-Sytek, A., Rask, T. S., Cobbold, S. A., Tonkin-Hill, G. Q., Subramaniam, K. S., Sexton, A. E., Creek, D. J., Daily, J. P., Duffy, M. F. & Day, K. P., 1 Mar 2018, In : FEBS Journal. 285, 5, p. 848-870 23 p.

Research output: Contribution to journalArticleResearchpeer-review

10 Citations (Scopus)

A label-free optical biosensor based on nanoporous anodic alumina for tumour necrosis factor-alpha detection in chronic wounds

Rajeev, G., Xifre-Perez, E., Prieto Simon, B., Cowin, A. J., Marsal, L. F. & Voelcker, N. H., 1 Mar 2018, In : Sensors and Actuators B: Chemical. 257, p. 116-123 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Alterations of Metabolic and Lipid Profiles in Polymyxin-Resistant Pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Anderson, D., Shen, H-H., Tsuji, B., Gutu, A. D., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jun 2018, In : Antimicrobial Agents and Chemotherapy. 62, 6, 14 p., e02656-17.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Altered Expression of Small Intestinal Drug Transporters and Hepatic Metabolic Enzymes in a Mouse Model of Familial Alzheimer's Disease

Pan, Y., Omori, K., Ali, I., Tachikawa, M., Terasaki, T., Brouwer, K. L. R. & Nicolazzo, J. A., 4 Sep 2018, In : Molecular Pharmaceutics. 15, 9, p. 4073-4083 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes

Cadet, F., Fontaine, N., Li, G., Sanchis, J., Ng Fuk Chong, M., Pandjaitan, R., Vetrivel, I., Offmann, B. & Reetz, M. T., 1 Dec 2018, In : Scientific Reports. 8, 1, 16757.

Research output: Contribution to journalArticleResearchpeer-review

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20 Citations (Scopus)

Arginine-Rich Manganese Silicate Nanobubbles as a Ferroptosis-Inducing Agent for Tumor-Targeted Theranostics

Wang, S., Li, F., Qiao, R., Hu, X., Liao, H., Chen, L., Wu, J., Wu, H., Zhao, M., Liu, J., Chen, R., Ma, X., Kim, D., Sun, J., Davis, T. P., Chen, C., Tian, J., Hyeon, T. & Ling, D., 26 Dec 2018, In : ACS Nano. 12, 12, p. 12380-12392 13 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

A tunable one-pot three-component synthesis of an 125I and Gd-labelled star polymer nanoparticle for hybrid imaging with MRI and nuclear medicine

Esser, L., Lengkeek, N. A., Moffat, B. A., Vu, M. N., Greguric, I., Quinn, J. F., Davis, T. P. & Whittaker, M. R., 7 Jul 2018, In : Polymer Chemistry. 9, 25, p. 3528-3535 8 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Benzoxaborole treatment perturbs S-adenosyl-L-methionine metabolism in Trypanosoma brucei

Steketee, P. C., Vincent, I. M., Achcar, F., Giordani, F., Kim, D. H., Creek, D., Freund, Y., Jacobs, R., Rattigan, K., Horn, D., Field, M. C., MacLeod, A. & Barrett, M. P., 14 May 2018, In : PLoS Neglected Tropical Diseases. 12, 5, 24 p., e0006450.

Research output: Contribution to journalArticleResearchpeer-review

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3 Citations (Scopus)

Bioconjugation and Fluorescence Labeling of Iron Oxide Nanoparticles Grafted with Bromomaleimide-Terminal Polymers

Qiao, R., Esser, L., Fu, C., Zhang, C., Hu, J., Ramírez-arcía, P., Li, Y., Quinn, J. F., Whittaker, M. R., Whittaker, A. K. & Davis, T. P., 12 Nov 2018, In : Biomacromolecules. 19, 11, p. 4423-4429 7 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Bulk and dispersed aqueous behaviour of an endogenous lipid, selachyl alcohol: Effect of Tween 80 and Pluronic F127 on nanostructure

Younus, M., Hawley, A., Boyd, B. J. & Rizwan, S. B., 1 Sep 2018, In : Colloids and Surfaces B: Biointerfaces. 169, p. 135-142 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Clickable Cubosomes for Antibody-Free Drug Targeting and Imaging Applications

Alcaraz, N., Liu, Q., Hanssen, E., Johnston, A. & Boyd, B. J., 17 Jan 2018, In : Bioconjugate Chemistry. 29, 1, p. 149-157 9 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid

Pan, Y., Short, J. L., Newman, S. A., Choy, K. H. C., Tiwari, D., Yap, C., Senyschyn, D., Banks, W. A. & Nicolazzo, J. A., May 2018, In : Brain, Behavior, and Immunity. 70, p. 36-47 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Combating Carbapenem-Resistant Acinetobacter baumannii by an Optimized Imipenem-plus-Tobramycin Dosage Regimen: Prospective Validation via Hollow-Fiber Infection and Mathematical Modeling

Landersdorfer, C. B., Yadav, R., Rogers, K. E., Kim, T. H., Shin, B. S., Boyce, J. D., Nation, R. L. & Bulitta, J. B., 1 Apr 2018, In : Antimicrobial Agents and Chemotherapy. 62, 4, 8 p., e02053-17.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Comparative analysis of phosphoethanolamine transferases involved in polymyxin resistance across 10 clinically relevant Gram-negative bacteria

Huang, J., Zhu, Y., Han, M., Li, M., Song, J., Velkov, T., Li, C. & Li, J., 1 Apr 2018, In : International Journal of Antimicrobial Agents. 51, 4, p. 586-593 8 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Comparison of the composition and in vitro activity of polymyxin B products

Diep, J. K., Covelli, J., Sharma, R., Ruszaj, D. M., Kaye, K. S., Li, J., Straubinger, R. M. & Rao, G. G., 2018, In : International Journal of Antimicrobial Agents. 52, 3, p. 365-371 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Concentration-dependent plasma protein binding: Expect the unexpected

On behalf of the International Society of Anti-Infective Pharmacology (ISAP), 15 Sep 2018, In : European Journal of Pharmaceutical Sciences. 122, p. 341-346 6 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Curcumin Attenuates Colistin-Induced Neurotoxicity in N2a Cells via Anti-inflammatory Activity, Suppression of Oxidative Stress, and Apoptosis

Dai, C., Ciccotosto, G. D., Cappai, R., Tang, S., Li, D., Xie, S., Xiao, X. & Velkov, T., 2018, In : Molecular Neurobiology. 55, 1, p. 421-434 14 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution

Larnaudie, S. C., Sanchis, J., Nguyen, T. H., Peltier, R., Catrouillet, S., Brendel, J. C., Porter, C. J. H., Jolliffe, K. A. & Perrier, S., 1 Sep 2018, In : Biomaterials. 178, p. 570-582 13 p.

Research output: Contribution to journalArticleResearchpeer-review

17 Citations (Scopus)

Cyclic Peptide-Polymer Nanotubes as Efficient and Highly Potent Drug Delivery Systems for Organometallic Anticancer Complexes

Larnaudie, S. C., Brendel, J. C., Romero-Canelón, I., Sanchez-Cano, C., Catrouillet, S., Sanchis, J., Coverdale, J. P. C., Song, J. I., Habtemariam, A., Sadler, P. J., Jolliffe, K. A. & Perrier, S., 8 Jan 2018, In : Biomacromolecules. 19, 1, p. 239-247 9 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Delivery of siRNA in vitro and in vivo using PEI-capped porous silicon nanoparticles to silence MRP1 and inhibit proliferation in glioblastoma

Tong, W. Y., Alnakhli, M., Bhardwaj, R., Apostolou, S., Sinha, S., Fraser, C., Kuchel, T., Kuss, B. & Voelcker, N. H., 13 Apr 2018, In : Journal of Nanobiotechnology. 16, 1, 17 p., 38.

Research output: Contribution to journalArticleResearchpeer-review

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2 Citations (Scopus)
1 Citation (Scopus)

Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli

Bergen, P. J., Bulitta, J. B., Sime, F. B., Lipman, J., McGregor, M. J., Millen, N., Paterson, D. L., Kirkpatrick, C. M. J., Roberts, J. A. & Landersdorfer, C. B., 1 May 2018, In : Diagnostic Microbiology and Infectious Disease. 91, 1, p. 69-76 8 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery

Yadav, P., McLeod, V. M., Nowell, C. J., Selby, L. I., Johnston, A. P. R., Kaminskas, L. M. & Trevaskis, N. L., 28 Feb 2018, In : Journal of Controlled Release. 272, p. 17-28 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Doxorubicin Conjugation and Drug Linker Chemistry Alter the Intravenous and Pulmonary Pharmacokinetics of a PEGylated Generation 4 Polylysine Dendrimer in Rats

Leong, N. J., Mehta, D., McLeod, V. M., Kelly, B. D., Pathak, R., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Sep 2018, In : Journal of Pharmaceutical Sciences. 107, 9, p. 2509-2513 5 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

Marxen, E., Jin, L., Jacobsen, J., Janfelt, C., Hyrup, B. & Nicolazzo, J. A., 1 Mar 2018, In : Pharmaceutical Research. 35, 3, 12 p., 70.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Efficient Binding, Protection, and Self-Release of dsRNA in Soil by Linear and Star Cationic Polymers

Whitfield, R., Anastasaki, A., Truong, N. P., Cook, A. B., Omedes-Pujol, M., Loczenski Rose, V., Nguyen, T. A. H., Burns, J. A., Perrier, S., Davis, T. P. & Haddleton, D. M., 21 Aug 2018, In : ACS Macro Letters. 7, 8, p. 909-915 7 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Electrochemical deposition of aminomalonitrile based films

Ball, V., Toh, R. J., Voelcker, N. H., Thissen, H. & Evans, R. A., 5 Sep 2018, In : Colloids and Surfaces A: Physicochemical and Engineering Aspects. 552, p. 124-129 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Electrospun composites of polycaprolactone and porous silicon nanoparticles for the tunable delivery of small therapeutic molecules

McInnes, S. J. P., Macdonald, T. J., Parkin, I. P., Nann, T. & Voelcker, N. H., 1 Apr 2018, In : Nanomaterials. 8, 4, 12 p., 205.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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11 Citations (Scopus)

Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly

Khor, S. Y., Vu, M. N., Pilkington, E. H., Johnston, A. P. R., Whittaker, M. R., Quinn, J. F., Truong, N. P. & Davis, T. P., 23 Aug 2018, In : Small. 14, 34, 13 p., 1801702.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Elucidating the pharmacokinetics/pharmacodynamics of aerosolized colistin against multidrug-resistant acinetobacter baumannii and klebsiella pneumoniae in a mouse lung infection model

Lin, Y-W., Zhou, Q. T., Han, M-L., Chen, K., Onufrak, N. J., Wang, J., Turnidge, J. D., Howden, B. P., Forrest, A., Chan, H. K. & Li, J., 1 Feb 2018, In : Antimicrobial Agents and Chemotherapy. 62, 2, 9 p., e01790.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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