Research Output 1975 2019

Filter
Article
2019

Local inflammation alters the lung disposition of a drug loaded pegylated liposome after pulmonary dosing to rats

Haque, S., Feeney, O., Meeusen, E., Boyd, B. J., McIntosh, M. P., Pouton, C. W., Whittaker, M. & Kaminskas, L. M., 10 Aug 2019, In : Journal of Controlled Release. 307, p. 32-43 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Location of Solvated Probe Molecules Within Nonionic Surfactant Micelles Using Molecular Dynamics

Warren, D. B., McPhee, E., Birru, W. A., Benameur, H., Chalmers, D. K. & Pouton, C. W., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 205-213 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Lymphatic Uptake of Liposomes after Intraperitoneal Administration Primarily Occurs via the Diaphragmatic Lymphatics and is Dependent on Liposome Surface Properties

Lee, G., Han, S., Inocencio, I., Cao, E., Hong, J., Phillips, A. R. J., Windsor, J. A., Porter, C. & Trevaskis, N., 2019, (Accepted/In press) In : Molecular Pharmaceutics.

Research output: Contribution to journalArticleResearchpeer-review

Magnetic nanoparticles enhance pore blockage-based electrochemical detection of a wound biomarker

Rajeev, G., Cowin, A. J., Voelcker, N. H. & Simon, B. P., 12 Jun 2019, In : Frontiers in Chemistry. 7, JUN, 11 p., 438.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging

Rudd, D., Benkendorff, K., Chahal, C., Guinan, T., Gustafsson, O. J. R., Esmaeelian, B., Krysinska, H., Pogson, L., Voelcker, N. H. & Abbott, C. A., 1 Dec 2019, In : Scientific Reports. 9, 1, 12342.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Maximizing RNA Loading for Gene Silencing Using Porous Silicon Nanoparticles

Tieu, T., Dhawan, S., Haridas, V., Butler, L. M., Thissen, H., Cifuentes-Rius, A. & Voelcker, N. H., 5 Jun 2019, In : ACS Applied Materials and Interfaces. 11, 26, p. 22993-23005 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Metabolomics study of the synergistic killing of polymyxin B in combination with amikacin against polymyxin-susceptible and resistant Pseudomonas aeruginosa

Hussein, M., Han, M-L., Zhu, Y., Zhou, Q. T., Lin, Y-W., Hancock, R. E. W., Hoyer, D., Creek, D. J., Li, J. & Velkov, T., 24 Sep 2019, (Accepted/In press) In : Antimicrobial Agents and Chemotherapy.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Metal-dependent inhibition of amyloid fibril formation: Synergistic effects of cobalt-tannic acid networks

Zhang, W., Christofferson, A. J., Besford, Q. A., Richardson, J. J., Guo, J., Ju, Y., Kempe, K., Yarovsky, I. & Caruso, F., 28 Jan 2019, In : Nanoscale. 11, 4, p. 1921-1928 8 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration

Dong, Y. D., Tchung, E., Nowell, C., Kaga, S., Leong, N., Mehta, D., Kaminskas, L. M. & Boyd, B. J., 2019, In : Journal of Liposome Research. 29, 1, p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Milk Lipids: A Complex Nutrient Delivery System

German, J. B., Argov-Argaman, N. & Boyd, B. J., 1 Jan 2019, In : Nestle Nutrition Institute Workshop Series. 90, p. 217-225 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
6 Citations (Scopus)

Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies

Cui, J., Ju, Y., Houston, Z. H., Glass, J. J., Fletcher, N. L., Alcantara, S., Dai, Q., Howard, C. B., Mahler, S. M., Wheatley, A. K., De Rose, R., Brannon, P. T., Paterson, B. M., Donnelly, P. S., Thurecht, K. J., Caruso, F. & Kent, S. J., 9 May 2019, In : Advanced Healthcare Materials. 8, 9, 10 p., 1801607.

Research output: Contribution to journalArticleResearchpeer-review

Multiparameter toxicity screening on a chip: Effects of UV radiation and titanium dioxide nanoparticles on HaCaT cells

McCormick, S., Smith, L. E., Holmes, A. M., Tong, Z., Lombi, E., Voelcker, N. H. & Priest, C., 1 Jul 2019, In : Biomicrofluidics. 13, 4, 8 p., 044112.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
7 Citations (Scopus)

Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide

Sun, Y., Kakinen, A., Xing, Y., Pilkington, E. H., Davis, T. P., Ke, P. C. & Ding, F., 1 Feb 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 2, p. 434-444 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

PD-L1– and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease

Galea, R., Nel, H. J., Talekar, M., Liu, X., Ooi, J. D., Huynh, M., Hadjigol, S., Robson, K. J., Ting, Y. T., Cole, S., Cochlin, K., Hitchcock, S., Zeng, B., Yekollu, S., Boks, M., Goh, N., Roberts, H., Rossjohn, J., Reid, H. H., Boyd, B. J. & 7 others, Malaviya, R., Shealy, D. J., Baker, D. G., Madakamutil, L., Richard Kitching, A., O’Sullivan, B. J. & Thomas, R., 19 Sep 2019, In : JCI Insight. 4, 18, 21 p., e126025.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

PEGylation and surface functionalization of liposomes containing drug nanocrystals for cell-targeted delivery

Xiao, Y., Liu, Q., Clulow, A. J., Li, T., Manohar, M., Gilbert, E. P., de Campo, L., Hawley, A. & Boyd, B. J., 1 Oct 2019, In : Colloids and Surfaces B: Biointerfaces. 182, 10 p., 110362.

Research output: Contribution to journalArticleResearchpeer-review

Photo-crosslinked coatings based on 2-hydroxypropyl acrylamide for the prevention of biofouling

Yoshikawa, C., Delalat, B., Huang, F., Braun, S., Nishijima, N., Voelcker, N. H., Kingshott, P. & Thissen, H., 16 Apr 2019, In : Journal of Materials Chemistry B. 7, 22, p. 3520-3527 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Physical and toxicological profiles of human IAPP amyloids and plaques

Kakinen, A., Sun, Y., Javed, I., Faridi, A., Pilkington, E. H., Faridi, P., Purcell, A. W., Zhou, R., Ding, F., Lin, S., Ke, P. C. & Davis, T. P., 15 Jan 2019, In : Science Bulletin. 64, 1, p. 26-35 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
2 Citations (Scopus)

Pointing in the right direction: Controlling the orientation of proteins on nanoparticles improves targeting efficiency

Yong, K. W., Yuen, D., Chen, M. Z., Porter, C. J. H. & Johnston, A. P. R., 13 Mar 2019, In : Nano Letters. 19, 3, p. 1827−1831 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Polydimethylsiloxane-based giant glycosylated polymersomes with tunable bacterial affinity

Martin, L., Gurnani, P., Zhang, J., Hartlieb, M., Cameron, N. R., Eissa, A. M. & Perrier, S., 11 Mar 2019, In : Biomacromolecules. 20, 3, p. 1297-1307 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Polymeric arsenicals as scaffolds for functional and responsive hydrogels

Tanaka, J., Song, J. I., Lunn, A. M., Hand, R. A., Häkkinen, S., Schiller, T. L., Perrier, S., Davis, T. P. & Wilson, P., 1 Jan 2019, In : Journal of Materials Chemistry B. 7, 27, p. 4263-4271 9 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Polymyxin acute kidney injury: Dosing and other strategies to reduce toxicity

Nation, R. L., Maria, M. H., Falci, D. R. & Zavascki, A. P., 1 Mar 2019, In : Antibiotics. 8, 1, 24.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Population pharmacokinetics of intravenous colistin in pediatric patients: Implications for selection of dosage regimens

Ooi, M. H., Ngu, S. J., Chor, Y. K., Li, J., Landersdorfer, C. B. & Nation, R. L., 26 Jan 2019, (Accepted/In press) In : Clinical Infectious Diseases. 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms

Guo, K., Sharma, A., Toh, R. J., Alvárez de Eulate, E., Gengenbach, T. R., Cetó, X., Voelcker, N. H. & Prieto-Simón, B., 13 Jun 2019, In : Advanced Functional Materials. 29, 24, 12 p., 1809206.

Research output: Contribution to journalArticleResearchpeer-review

Post-Genomic Approaches to Understanding Malaria Parasite Biology: Linking Genes to Biological Functions

Sexton, A. E., Doerig, C., Creek, D. J. & Carvalho, T. G., 9 Aug 2019, In : ACS Infectious Diseases. 5, 8, p. 1269-1278 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Probing cell-nanoparticle (cubosome) interactions at the endothelial interface: do tissue dimension and flow matter?

Tan, A., Lam, Y. Y., Pacot, O., Hawley, A. & Boyd, B. J., 1 Aug 2019, In : Biomaterials Science. 7, 8, p. 3460-3470 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Probing the Aggregation and Immune Response of Human Islet Amyloid Polypeptides with Ligand-Stabilized Gold Nanoparticles

Javed, I., He, J., Kakinen, A., Faridi, A., Yang, W., Davis, T. P., Ke, P. C. & Chen, P., 20 Mar 2019, In : ACS Applied Materials and Interfaces. 11, 11, 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Promoting intestinal lymphatic transport targets a liver-X receptor (LXR) agonist (WAY-252,623) to lymphocytes and enhances immunomodulation

Cao, E., Lindgren, A., Martinsson, S., Hu, L., Lindfors, L., Sigfridsson, K., Skantze, U., Michaëlsson, E., Trevaskis, N. L. & Porter, C. J. H., 28 Feb 2019, In : Journal of Controlled Release. 296, p. 29-39 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Protein Adsorption and Coordination-Based End-Tethering of Functional Polymers on Metal-Phenolic Network Films

Tardy, B. L., Richardson, J. J., Nithipipat, V., Kempe, K., Guo, J., Cho, K. L., Rahim, M. A., Ejima, H. & Caruso, F., 11 Mar 2019, In : Biomacromolecules. 20, 3, p. 1421-1428 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Qualitative formative implementation research to inform introduction of a new essential medicine

Oliver, V. L., Tolera, M., Teklu, A. M., Minaye, A., Lambert, P. & McIntosh, M. P., 1 Jan 2019, (Accepted/In press) In : Research in Social and Administrative Pharmacy.

Research output: Contribution to journalArticleResearchpeer-review

Rapid Assessment of Nanoparticle Extravasation in a Microfluidic Tumor Model

Vu, N. M., Rajasekhar, P., Poole, D. P., Khor, S. Y., Truong Phuoc, N., Nowell, C., Quinn, J. F., Whittaker, M., Veldhuis, N. & Davis, T. P., 29 Mar 2019, In : ACS Applied Nano Materials. 2, 4, p. 1844-1856 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
4 Citations (Scopus)

Rational Management of Photons for Enhanced Photocatalysis in Structurally-Colored Nanoporous Anodic Alumina Photonic Crystals

Lim, S. Y., Law, C. S., Markovic, M., Marsal, L. F., Voelcker, N. H., Abell, A. D. & Santos, A., 25 Feb 2019, In : ACS Applied Energy Materials. 2, 2, p. 1169-1184 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Removal of interstitial hyaluronan with recombinant human hyaluronidase improves the systemic and lymphatic uptake of cetuximab in rats

Styles, I. K., Feeney, O. M., Nguyen, T-H., Brundel, D., Kang, D. W., Clift, R., McIntosh, M. P. & Porter, C. J. H., 10 Dec 2019, In : Journal of Controlled Release. 315, p. 85-96 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Replica moulded poly(dimethylsiloxane) microwell arrays induce localized endothelial cell immobilization for coculture with pancreatic islets

Burzava, A. L. S., Forget, A., Harding, F. J., Cockshell, M. P., Penko, D., Rouzaud, C., Ahmadi, V., Marina, P. F., Rojas-Canales, D., Bonder, C. S., Coates, P. T. H., Waibel, M., Thomas, H. E., Kay, T. W., Loudovaris, T., Blencowe, A. & Voelcker, N. H., 30 Jan 2019, In : Biointerphases. 14, 1, 8 p., 011002.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Replication of a Tissue Microenvironment by Thermal Scanning Probe Lithography

Tang, S. W., Uddin, M. H., Tong, W. Y., Pasic, P., Yuen, W., Thissen, H., Lam, Y. W. & Voelcker, N. H., 3 May 2019, In : ACS Applied Materials and Interfaces. 11, 21, p. 18988-18994 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Revisiting cell–particle association in vitro: A quantitative method to compare particle performance

Faria, M., Noi, K. F., Dai, Q., Björnmalm, M., Johnston, S. T., Kempe, K., Caruso, F. & Crampin, E. J., 10 Aug 2019, In : Journal of Controlled Release. 307, p. 355-367 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
5 Citations (Scopus)

Revisiting dispersible milk-drug tablets as a solid lipid formulation in the context of digestion

Binte Abu Bakar, S. Y., Salim, M., Clulow, A. J., Hawley, A. & Boyd, B. J., 10 Jan 2019, In : International Journal of Pharmaceutics. 554, p. 179-189 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Self-Assembling Protein-Polymer Bioconjugates for Surfaces with Antifouling Features and Low Nonspecific Binding

Liu, Y., Nevanen, T. K., Paananen, A., Kempe, K., Wilson, P., Johansson, L. S., Joensuu, J. J., Linder, M. B., Haddleton, D. M. & Milani, R., 23 Jan 2019, In : ACS Applied Materials and Interfaces. 11, 3, p. 3599-3608 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Single-Molecular Heteroamyloidosis of Human Islet Amyloid Polypeptide

Kakinen, A., Xing, Y., Hegoda Arachchi, N., Javed, I., Feng, L., Faridi, A., Douek, A. M., Sun, Y., Kaslin, J., Davis, T. P., Higgins, M. J., Ding, F. & Ke, P. C., 11 Sep 2019, In : Nano Letters. 19, 9, p. 6535-6546 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Soft and Condensed Nanoparticles and Nanoformulations for Cancer Drug Delivery and Repurpose

Yang, W., Veroniaina, H., Qi, X., Chen, P., Li, F. & Ke, P. C., 2019, (Accepted/In press) In : Advanced Therapeutics.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
1 Citation (Scopus)

Solid-State Behavior and Solubilization of Flash Nanoprecipitated Clofazimine Particles during the Dispersion and Digestion of Milk-Based Formulations

Salim, M., Ramirez, G., Clulow, A. J., Zhang, Y., Ristroph, K. D., Feng, J., McManus, S. A., Hawley, A., Prud'Homme, R. K. & Boyd, B. J., 3 Jun 2019, In : Molecular Pharmaceutics. 16, 6, p. 2755-2765 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Solid State Characterization of Ciprofloxacin Liposome Nanocrystals

Li, T., Mudie, S., Cipolla, D., Rades, T. & Boyd, B. J., 7 Jan 2019, In : Molecular Pharmaceutics. 16, 1, p. 184-194 11 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Spatially Controlled Surface Modification of Porous Silicon for Sustained Drug Delivery Applications

Zhang, D. X., Yoshikawa, C., Welch, N. G., Pasic, P., Thissen, H. & Voelcker, N. H., 4 Feb 2019, In : Scientific Reports. 9, 1, 11 p., 1367.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Stimulus-Responsive Antibiotic Releasing Systems for the Treatment of Wound Infections

Schultz, H. B., Vasani, R. B., Holmes, A. M., Roberts, M. S. & Voelcker, N. H., 18 Feb 2019, In : ACS Applied Bio Materials. 2, 2, p. 704-716 13 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

Boyd, B. J., Bergström, C. A. S., Vinarov, Z., Kuentz, M., Brouwers, J., Augustijns, P., Brandl, M., Bernkop-Schnürch, A., Shrestha, N., Préat, V., Müllertz, A., Bauer-Brandl, A. & Jannin, V., 1 Sep 2019, In : European Journal of Pharmaceutical Sciences. 137, 27 p., 104967.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Surface radio-mineralisation mediates chelate-free radiolabelling of iron oxide nanoparticles

Patrick, P. S., Bogart, L. K., Macdonald, T. J., Southern, P., Powell, M. J., Zaw-Thin, M., Voelcker, N. H., Parkin, I. P., Pankhurst, Q. A., Lythgoe, M. F., Kalber, T. L. & Bear, J. C., 9 Jan 2019, In : Chemical Science. 10, 9, p. 2592-2597 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Synergistic Combination of Polymyxin B and Enrofloxacin Induced Metabolic Perturbations in Extensive Drug-resistant Pseudomonas aeruginosa

Lin, Y-W., Han, M-L., Zhao, J., Zhu, Y., Rao, G., Forrest, A., Song, J., Kaye, K. S., Hertzog, P., Purcell, A., Creek, D., Zhou, T. Q., Velkov, T. & Li, J., 3 Oct 2019, In : Frontiers in Pharmacology. 10, 11 p., 1146.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File
1 Citation (Scopus)

Synthesis and identification of novel pryidazinylpyrazolone based diazo compounds as inhibitors of human islet amyloid polypeptide aggregation

Bin Farrukh, S. U., Javed, I., Ather, A. Q., Emwas, A-H., Alazmi, M., Gao, X., Chotana, G. A., Davis, T. P., Ke, P. C. & Saleem, R. S. Z., Mar 2019, In : Bioorganic Chemistry. 84, p. 339-346 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Systematic Evaluation of Transferrin-Modified Porous Silicon Nanoparticles for Targeted Delivery of Doxorubicin to Glioblastoma

Luo, M., Lewik, G., Ratcliffe, J. C., Choi, C. H. J., Mäkilä, E., Tong, W. Y. & Voelcker, N. H., 1 Jan 2019, In : ACS Applied Materials and Interfaces. 11, 37, p. 33637−33649 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Tailor-made solvents for pharmaceutical use? Experimental and computational approach for determining solubility in deep eutectic solvents (DES)

Palmelund, H., Andersson, M. P., Asgreen, C. J., Boyd, B. J., Rantanen, J. & Löbmann, K., 1 Dec 2019, In : International Journal of Pharmaceutics: X. 1, p. 1-9 9 p., 100034.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File

Temperature stability of oxytocin ampoules labelled for storage at 2°C-8°C and below 25°C: an observational assessment under controlled accelerated and temperature cycling conditions

Nguyen, T-H., Lambert, P., Minhas, R. S., McEvoy, C., Deadman, K., Wright, P., Prankerd, R. J., Mogatle, S. & McIntosh, M. P., 26 Jul 2019, In : BMJ Open. 9, 7, p. 1-7 7 p., e029083.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
File