Research Output 1975 2019

Filter
Article
2009
25 Citations (Scopus)

Influence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation

Das, S. C., Larson, I. C., Young, P. M. & Stewart, P. J., 2009, In : Journal of Pharmaceutical Sciences. 98, p. 1015 - 1027 12 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Influence of the polydispersity of the added fine lactose on the dispersion of salmeterol xinafoate from mixtures for inhalation

Adi, H., Larson, I. C. & Stewart, P. J., 2009, In : European Journal of Pharmaceutical Sciences. 36, 2-3, p. 265 - 274 10 p.

Research output: Contribution to journalArticleResearchpeer-review

32 Citations (Scopus)

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism

Trevaskis, N., Shackleford, D., Charman, W. N., Edwards, G. A., Gardin, A., Appel-Dingemanse, S., Kretz, O., Galli, B. & Porter, C. J., 2009, In : Pharmaceutical Research. 26, 6, p. 1486 - 1495 10 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Liquid crystalline coated drug particles as a potential route to long acting intravitreal steroids

Tilley, A. J., Morton, D. A. V., Hanley, T. & Boyd, B. J., 2009, In : Current Drug Delivery. 6, 4, p. 322 - 331 10 p.

Research output: Contribution to journalArticleResearchpeer-review

89 Citations (Scopus)

Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: characterisation, swelling and release kinetics

Rizwan, S. B., Hanley, T., Boyd, B. J., Rades, T. & Hook, S., 2009, In : Journal of Pharmaceutical Sciences. 98, 11, p. 4191 - 4204 14 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)
98 Citations (Scopus)

Miniature inhalation therapy platform using surface acoustic wave microfluidic atomization

Qi, A., Friend, J., Yeo, L. Y-M., Morton, D. A. V., McIntosh, M. P. & Spiccia, L., 2009, In : Lab on a Chip. 9, p. 2184 - 2193 10 p.

Research output: Contribution to journalArticleResearchpeer-review

138 Citations (Scopus)

Nanostructure of liquid crystalline matrix determines in vitro sustained release and in vivo oral absorption kinetics for hydrophilic model drugs

Lee, K. W-Y., Nguyen, T-H., Hanley, T. & Boyd, B. J., 2009, In : International Journal of Pharmaceutics. 365, 1-2, p. 190 - 199 10 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Nonlamellar liquid crystalline nanostructured particles: advances in materials and structure determination

Boyd, B. J., Dong, Y-D. & Rades, T., 2009, In : Journal of Liposome Research. 19, 1, p. 12 - 28 17 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Oral bioavailability assessment and intestinal lymphatic transport of org 45697 and org 46035, two highly lipophilic novel immunomodulator analogues

Caliph, S. M., Faassen, W. A., Vogel, G. M. & Porter, C. J., 2009, In : Current Drug Delivery. 6, 4, p. 359 - 366 8 p.

Research output: Contribution to journalArticleResearchpeer-review

35 Citations (Scopus)

Overcoming biological barriers to in vivo efficacy of antisense oligonucleotides.

White, P. J., Anastasopoulos, F., Pouton, C. W. & Boyd, B. J., 2009, In : Expert Reviews in Molecular Medicine. 11, e10, p. 1 - 19 19 p.

Research output: Contribution to journalArticleResearchpeer-review

26 Citations (Scopus)

Partly-PEGylated poly-L-lysine dendrimers have reduced plasma stability and circulation times compared with fully PEGylated dendrimers

Kaminskas, L. M., Wu, Z., Barlow, N., Krippner, G. Y., Boyd, B. J. & Porter, C. J. H., 2009, In : Journal of Pharmaceutical Sciences. 98, 10, p. 3871 - 3875 5 p.

Research output: Contribution to journalArticleResearchpeer-review

79 Citations (Scopus)

PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats

Kaminskas, L. M., Kota, J., McLeod, V. M., Kelly, B. D., Karellas, P. & Porter, C. J., 2009, In : Journal of Controlled Release. 140, 2, p. 108 - 116 9 p.

Research output: Contribution to journalArticleResearchpeer-review

108 Citations (Scopus)

Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly-L-lysine dendrimers

Kaminskas, L. M., Kelly, B. D., McLeod, V. M., Boyd, B. J., Krippner, G. Y., Williams, E. & Porter, C. J., 2009, In : Molecular Pharmaceutics. 6, 4, p. 1190 - 1204 15 p.

Research output: Contribution to journalArticleResearchpeer-review

50 Citations (Scopus)

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)

Burns, C., Bourke, D. G., Andrau, L., Bu, X., Charman, S. A., Donohue, A. C., Fantino, E., Farrugia, M., Feutrill, J. T., Joffe, M., Kling, R. M., Kurek, M., Nero, T. L., Nguyen, T., Palmer, J. T., Phillips, I. D., Shackleford, D., Sikanyika, H., Styles, M., Su, S. & 3 others, Treutlein, H. R., Zeng, J. & Wilks, A. F., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 20, p. 5887 - 5892 6 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Positron annihilation lifetime spectroscopy (PALS) as a characterization technique for nanostructured self-assembled amphiphile systems

Dong, A., Pascual-Izzara, C., Pas, S. J., Hill, A., Boyd, B. J. & Drummond, C. J., 2009, In : Journal of Physical Chemistry B. 113, 1, p. 84 - 91 8 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Probing the fibrate binding specificity of rat liver fatty acid binding protein

Chuang, S., Velkov, T., Horne, H. J., Wielens, J., Chalmers, D. K., Porter, C. J. & Scanlon, M., 2009, In : Journal of Medicinal Chemistry. 52, 17, p. 5344 - 5355 12 p.

Research output: Contribution to journalArticleResearchpeer-review

40 Citations (Scopus)

S-glycosyl primary sulfonamides - A new structural class for selective inhibition of cancer-associated carbonic anhydrases

Lopez, M., Paul, B., Hofmann, A., Morizzi, J., Wu, Q. K., Charman, S. A., Innocenti, A., Vullo, D., Supuran, C. T. & Poulsen, S. A., 22 Oct 2009, In : Journal of Medicinal Chemistry. 52, 20, p. 6421-6432 12 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Short-term changes in drug agglomeration within interactive mixtures following blending

Andreou, J., Stewart, P. & Morton, D., 2009, In : International Journal of Pharmaceutics. 372, 1-2, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)
21 Citations (Scopus)

Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: Relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity

Wang, X., Creek, D. J., Schiaffo, C. E., Dong, Y., Chollet, J., Scheurer, C., Wittlin, S., Charman, S. A., Dussault, P. H., Wood, J. K. & Vennerstrom, J., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4542 - 4545 4 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Stability of peroxide antimalarials in the presence of human hemoglobin

Creek, D. J., Ryan, E., Charman, W. N., Chiu, F. C. K., Prankerd, R., Vennerstrom, J. & Charman, S. A., 2009, In : Antimicrobial Agents and Chemotherapy. 53, 8, p. 3496 - 3500 5 p.

Research output: Contribution to journalArticleResearchpeer-review

203 Citations (Scopus)

Stimuli responsive liquid crystals provide 'on-demand' drug delivery in vitro and in vivo

Fong, W. K., Hanley, T. L. & Boyd, B. J., 2009, In : Journal of Controlled Release. 135, 3, p. 218 - 226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Surface energy changes and their relationship with the dispersibility of salmeterol xinafoate powders for inhalation after storage at high RH

Das, S. C., Larson, I. C., Young, P. M. & Stewart, P. J., 2009, In : European Journal of Pharmaceutical Sciences. 38, 4, p. 347 - 354 8 p.

Research output: Contribution to journalArticleResearchpeer-review

45 Citations (Scopus)

The role of force control agents in high-dose dry powder inhaler formulations

Begat, P., Morton, D. A. V., Shur, J., Kippax, P., Staniforth, J. N. & Price, R., 2009, In : Journal of Pharmaceutical Sciences. 98, 8, p. 2770 - 2783 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2010
77 Citations (Scopus)

Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins

Rizwan, S., Boyd, B., Rades, T. & Hook, S., 2010, In : Expert Opinion on Drug Delivery. 7, 10, p. 1133 - 1144 12 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Brain uptake of diazepam and phenytoin in a genetic animal model of absence epilepsy

Nicolazzo, J., Steuten, J. A., Charman, S. A., Taylor, N., Davies, P. & Petrou, S., 2010, In : Clinical and Experimental Pharmacology and Physiology. 37, p. 647 - 649 3 p.

Research output: Contribution to journalArticleResearchpeer-review

126 Citations (Scopus)
36 Citations (Scopus)

Discovery of novel benzo[ a ]phenoxazine SSJ-183 as a drug candidate for malaria

Ge, J-F., Arai, C., Yang, M., Bakar, A., Lu, J., Ismail, N. S. M., Wittlin, S., Kaiser, M., Brun, R., Charman, S. A., Nguyen, T., Morizzi, J., Itoh, I. & Ihara, M., 2010, In : ACS Medicinal Chemistry Letters. 1, 7, p. 360 - 364 5 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)

Diverse ordered 3D nanostructured amphiphile self-assembly materials found in protic ionic liquids

Mulet, X., Kennedy, D., Greaves, T., Waddington, L., Hawley, A., Kirby, N. & Drummond, C., 2010, In : Journal of Physical Chemistry Letters. 1, 18, p. 2651 - 2654 4 p.

Research output: Contribution to journalArticleResearchpeer-review

103 Citations (Scopus)

Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution

Dube, A., Ng, K., Nicolazzo, J. & Larson, I. C., 2010, In : Food Chemistry. 122, p. 662 - 667 6 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Effect of electroacupuncture on the third lumbar transverse process syndrome: A randomized controlled trial

Miao, E. & Miao, M., 2010, In : Medical Acupuncture. 22, 4, p. 249 - 255 7 p.

Research output: Contribution to journalArticleResearchpeer-review

30 Citations (Scopus)

Efficacy of antimicrobial polymer coatings in an animal model of bacterial infection associated with foreign body implants

Hart, E., Azzopardi, K., Taing, H., Graichen, F., Jeffery, J., Mayadunne, R., Wickramaratna, M., OShea, M., Nijagal, B., Watkinson, R., OLeary, S., Finnin, B., Tait, R. & Robins-Browne, R., 2010, In : Journal of Antimicrobial Chemotherapy. 65, 5, p. 974 - 980 7 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

High throughput preparation and characterisation of amphiphilic nanostructured nanoparticulate drug delivery vehicles

Mulet, X., Kennedy, D., Conn, C., Hawley, A. & Drummond, C., 2010, In : International Journal of Pharmaceutics. 395, 1-2, p. 290 - 297 8 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Impact of chlorpromazine self-association on its apparent binding constants with cyclodextrins: Effect of SBE7-beta-CD on the disposition of chlorpromazine in the rat

McIntosh, M. P., Leong, N., Katneni, K., Morizzi, J., Shackleford, D. M. & Prankerd, R. J., 2010, In : Journal of Pharmaceutical Sciences. 99, 7, p. 2999 - 3008 10 p.

Research output: Contribution to journalArticleResearchpeer-review

69 Citations (Scopus)

Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach

Zhou, Q., Qu, L., Larson, I. C., Stewart, P. J. & Morton, D. A. V., 2010, In : International Journal of Pharmaceutics. 394, 1-Feb, p. 50 - 59 10 p.

Research output: Contribution to journalArticleResearchpeer-review

61 Citations (Scopus)

Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating

Zhou, Q., Armstrong, B., Larson, I. C., Stewart, P. J. & Morton, D. A. V., 2010, In : Journal of Pharmaceutical Sciences. 99, 2, p. 969 - 981 13 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in biabetic mice

Urban, M., Li, C., Yu, C., Lu, Y., Krise, J., McIntosh, M. P., Rajewski, R. A., Blagg, B. & Dobrowsky, R. T., 2010, In : ASN Neuro. 2, 4, p. 189 - 199 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Ligand-enhanced expression and in-cell assay of human peroxisome proliferator-activated receptor alpha ligand binding domain

Velkov, T., Rimmer, K. & Headey, S., 2010, In : Protein Expression and Purification. 70, 2, p. 260 - 269 10 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism?

Tay, T., Das, S. C. & Stewart, P. J., 2010, In : International Journal of Pharmaceutics. 383, p. 62 - 69 8 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Monodisperse nonionic phytanyl ethylene oxide surfactants: High throughput lyotropic liquid crystalline phase determination and the formation of liposomes, hexosomes and cubosomes

Fong, C., Weerawardena, A., Sagnella, S., Mulet, X., Waddington, L., Krodkiewska, I. & Drummond, C., 2010, In : Soft Matter. 6, 19, p. 4727 - 4741 15 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Nanostructured nonionic thymidine nucleolipid self-assembly materials

Mulet, X., Kaasgaard, T., Conn, C., Waddington, L., Kennedy, D., Weerawardena, A. & Drummond, C., 2010, In : Langmuir: the ACS journal of surfaces and colloids. 26, 23, p. 18415 - 18423 9 p.

Research output: Contribution to journalArticleResearchpeer-review

48 Citations (Scopus)

Nonequilibrium effects in self-assembled mesophase materials: unexpected supercooling effects for cubosomes and hexosomes

Dong, C. Y-D., Tilley, A. J., Larson, I. C., Lawrence, J., Amenitsch, H., Rappolt, M., Hanley, T. L. & Boyd, B. J., 2010, In : Langmuir: the ACS journal of surfaces and colloids. 26, 11, p. 9000 - 9010 11 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)
64 Citations (Scopus)

Plasmonic nanorods provide reversible control over nanostructure of self-assembled drug delivery materials

Fong, W. K., Hanley, T. L., Thierry, B., Kirby, N. & Boyd, B. J., 2010, In : Langmuir: the ACS journal of surfaces and colloids. 26, 9, p. 6136 - 6139 4 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Preclinical comparison of intravenous melphalan pharmacokinetics administered in formulations containing either (SBE)7m-beta-cyclodextrin or a co-solvent system

Koltun, M., Morizzi, J., Katneni, K., Charman, S. A., Shackleford, D. & McIntosh, M. P., 2010, In : Biopharmaceutics and Drug Disposition. 31, 8-9, p. 450 - 454 5 p.

Research output: Contribution to journalArticleResearchpeer-review

37 Citations (Scopus)

Self-assembly behavior of colistin and its prodrug colistin methanesulfonate: implications for solution stability and solubilization

Wallace, S. J., Li, J., Nation, R. L., Prankerd, R. J., Velkov, T. & Boyd, B. J., 2010, In : Journal of Physical Chemistry B. 114, p. 4836 - 4840 5 p.

Research output: Contribution to journalArticleResearchpeer-review

71 Citations (Scopus)

Silica nanoparticles to control the lipase-mediated digestion of lipid-based oral delivery systems

Tan, A., Simovic, S., Davey, A., Rades, T., Boyd, B. J. & Prestidge, C. A., 2010, In : Molecular Pharmaceutics. 7, 2, p. 522 - 532 11 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Sulfonamide linked neoglycoconjugates-A new class of inhibitors for cancer-associated carbonic anhydrases

Lopez, M., Bornaghi, L. F., Innocenti, A., Vullo, D., Charman, S. A., Supuran, C. T. & Poulsen, S-A., 2010, In : Journal of Medicinal Chemistry. 53, p. 2913 - 2926 14 p.

Research output: Contribution to journalArticleResearchpeer-review