Research Output 1975 2020

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2007
20 Citations (Scopus)

Laser diffraction particle sizing of cohesive lactose powders

Adi, H., Larson, I. C. & Stewart, P. J., 2007, In : Powder Technology. 179, 1-2, p. 90 - 94 5 p.

Research output: Contribution to journalArticleResearchpeer-review

1070 Citations (Scopus)

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

Porter, C. J., Trevaskis, N. & Charman, W. N., 2007, In : Nature Reviews Drug Discovery. 6, 14, p. 231 - 248 18 p.

Research output: Contribution to journalArticleResearchpeer-review

66 Citations (Scopus)

Low dose lipid formulations: effects on gastric emptying and biliary secretion

Kossena, G. A., Charman, W. N., Wilson, C., O'Mahony, B., Lindsay, B., Hempenstall, J., Davidson, C., Crowley, P. & Porter, C. J., 2007, In : Pharmaceutical Research. 24, 11, p. 2084 - 2096 13 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Lymphatic absorption of subcutaneously administered proteins: influence of different injection sites on the absorption of darbepoetin alfa using a sheep model

Kota, J., Machavaram, K. K., McLennan, D. N., Edwards, G. A., Porter, C. J. & Charman, S. A., 2007, In : Drug Metabolism and Disposition. 35, 12, p. 2211 - 2217 7 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Probing the Flexibility of the DsbA Oxidoreductase from Vibrio cholerae-a 15N - 1H Heteronuclear NMR Relaxation Analysis of Oxidized and Reduced Forms of DsbA

Horne, H. J., d'Auvergne, E. J., Coles, M., Velkov, T., Chin, Y., Charman, W. N., Prankerd, R. J., Gooley, P. & Scanlon, M., 2007, In : Journal of Molecular Biology. 371, 3, p. 703 - 716 14 p.

Research output: Contribution to journalArticleResearchpeer-review

56 Citations (Scopus)

Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions: hexosomes are not necessarily flat hexagonal prisms

Boyd, B. J., Rizwan, S., Dong, Y-D., Hook, S. M. & Rades, T., 2007, In : Langmuir: the ACS journal of surfaces and colloids. 23, 25, p. 12461 - 12464 4 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

Single quadrupole mass spectrometry for pre-clinical pharmacokinetic analysis: Quantitation of carvedilol in dog plasma

McIntosh, M. P., Carlson, B. J., Schorno, K. S. & Rajewski, R. A., 2007, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 852, p. 665 - 668 4 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Spiro- and dispiro-1,2-dioxolanes: contribution of iron(II)-mediated one-electron vs two-electron reduction to the activity of antimalarial peroxides

Wang, X., Dong, Y., Wittlin, S., Creek, D., Chollet, J., Charman, S. A., Santo Tomas, J., Scheurer, C., Snyder, C. & Vennerstrom, J., 2007, In : Journal of Medicinal Chemistry. 50, 23, p. 5840 - 5847 8 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Use of milling and wet sieving to produce narrow particle size distributions of lactose monohydrate in the sub-sieve range

Adi, H., Larson, I. C. & Stewart, P. J., 2007, In : Powder Technology. 179, 1-2, p. 95 - 99 5 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides

Tang, Y., Dong, Y., Wittlin, S., Charman, S. A., Chollet, J., Chiu, F. C. K., Charman, W. N., Matile, H., Urwyler, H., Dorn, A., Bajpai, S., Wang, X., Padmanilayam, M., Karle, J. M., Brun, R. & Vennerstrom, J., 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 5, p. 1260 - 1265 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2008
16 Citations (Scopus)
8 Citations (Scopus)

A protocol for the combined sub-fractionation and delipidation of lipid binding proteins using hydrophobic interaction chromatography

Velkov, T., Lim, M. L. R., Capuano, B. & Prankerd, R. J., 2008, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 867, 2, p. 238 - 246 9 p.

Research output: Contribution to journalArticleResearchpeer-review

53 Citations (Scopus)

Characterization of the drug binding specificity of rat liver fatty acid binding protein

Chuang, S., Velkov, T., Horne, J., Porter, C. J. & Scanlon, M., 2008, In : Journal of Medicinal Chemistry. 51, 13, p. 3755 - 3764 10 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277

Zhou, L., Alker, A., Ruf, A., Wang, X., Chiu, F. C. K., Morizzi, J., Charman, S. A., Charman, W. N., Scheurer, C., Wittlin, S., Dong, Y., Hunziker, D. & Vennerstrom, J., 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 5, p. 1555 - 1558 4 p.

Research output: Contribution to journalArticleResearchpeer-review

52 Citations (Scopus)

Cospray dried antibiotics for dry powder lung delivery

Adi, H., Young, P. M., Chan, H-K., Stewart, P. J., Agus, H. & Traini, D., 2008, In : Journal of Pharmaceutical Sciences. 97, p. 3356 - 3366 10 p.

Research output: Contribution to journalArticleResearchpeer-review

459 Citations (Scopus)

Enhancing intestinal drug solubilisation using lipid-based delivery systems

Porter, C. J., Pouton, C. W., Cuine, J. & Charman, W. N., 2008, In : Advanced Drug Delivery Reviews. 60, 6, p. 673 - 691 19 p.

Research output: Contribution to journalArticleResearchpeer-review

132 Citations (Scopus)

Evaluation of the impact of surfactant digestion on the bioavailability of Danazol after oral administration of lipidic self-emulsifying formulations to dogs

Cuine, J., McEvoy, C. L., Charman, W. N., Pouton, C. W., Edwards, G. A., Benameur, H. & Porter, C. J., 2008, In : Journal of Pharmaceutical Sciences. 97, 2, p. 995 - 1012 18 p.

Research output: Contribution to journalArticleResearchpeer-review

492 Citations (Scopus)

Formulation of lipid-based delivery systems for oral administration: Materials, methods and strategies

Pouton, C. W. & Porter, C. J., 2008, In : Advanced Drug Delivery Reviews. 60, 6, p. 625 - 637 13 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Generic construction of single component particles that elicit humoural and cellular immune responses without the need for adjuvants

White, P. J., Anastasopoulos, F., Church, J. E., Kuo, C-Y. J., Boyd, B. J., Hickey, P. LC., Sze Tu, L., Burns, P., Lew, A. M., Heath, W. R., Davey, G. M. & Pouton, C. W., 2008, In : Vaccine. 26, 52, p. 6824 - 6831 8 p.

Research output: Contribution to journalArticleResearchpeer-review

14 Citations (Scopus)

Genistein- and daidzein 7-O-beta-D-glucuronic acid retain the ability to inhibit copper-mediated lipid oxidation of low density lipoprotein

Kgomotso, T., Chiu, F. C. K. & Ng, K., 2008, In : Molecular Nutrition and Food Research. 52, 12, p. 1457 - 1466 10 p.

Research output: Contribution to journalArticleResearchpeer-review

74 Citations (Scopus)

Impurities in commercial phytantriol significantly alter its lyotropic liquid-crystalline phase behavior

Dong, Y-D., Dong, A., Larson, I. C., Rappolt, M., Amenitsch, H., Hanley, T. L. & Boyd, B. J., 2008, In : Langmuir: the ACS journal of surfaces and colloids. 24, 13, p. 6998 - 7003 6 p.

Research output: Contribution to journalArticleResearchpeer-review

236 Citations (Scopus)

Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update

Trevaskis, N., Charman, W. N. & Porter, C. J., 2008, In : Advanced Drug Delivery Reviews. 60, 6, p. 702 - 716 15 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Navigating transdermal diffusion with multiphoton fluorescence lifetime imaging

Bird, D. K., Schneider, A. L., Watkinson, A. C., Finnin, B. C. & Smith, T. A., 2008, In : Journal of Microscopy. 230, 1, p. 61 - 69 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Ni2+-Based Immobilized Metal Ion Affinity Chromatography of Lactose Operon Repressor Protein from Escherichia Coli

Velkov, T., Jones, A. & Lim, M. L. R., 2008, In : Preparative Biochemistry & Biotechnology. 38, 4, p. 422 - 441 20 p.

Research output: Contribution to journalArticleResearchpeer-review

68 Citations (Scopus)

Past and future evolution in colloidal drug delivery systems

Boyd, B. J., 2008, In : Expert Opinion on Drug Delivery. 5, 1, p. 69 - 85 17 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Pharmacokinetics and brain uptake of AM-36, a novel neuroprotective agent, following intravenous administration to rats

Nicolazzo, J., Nguyen, T. T., Katneni, K., Steuten, J. A., Smith, G. D., Jarrott, B., Callaway, J. K. & Charman, S. A., 2008, In : Journal of Pharmacy and Pharmacology. 60, 2, p. 171 - 178 8 p.

Research output: Contribution to journalArticleResearchpeer-review

51 Citations (Scopus)

Pharmacy Education in the Context of Australian Practice

Marriott, J. L., Nation, R. L., Roller, L., Costelloe, M. T., Galbraith, K. J., Stewart, P. J. & Charman, W. N., 2008, In : American Journal of Pharmaceutical Education. 72, 6, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Preparation and in vitro evaluation of novel lipopeptide transfection agents for efficient gene delivery

Tarwadi, T., Jazayeri, J., Prankerd, R. & Pouton, C. W., 2008, In : Bioconjugate Chemistry. 19, 4, p. 940 - 950 11 p.

Research output: Contribution to journalArticleResearchpeer-review

500 Citations (Scopus)

Rapid restoration of cognition in alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

Adlard, P. A., Cherny, R. A., Finklestein, D. I., Gautier, E., Robb, E., Cortes, M., Volitakis, I., Liu, X., Smith, J. P., Perez, K., Laughton, K. M., Lin, Q-X., Charman, S. A., Nicolazzo, J., Wilkins, S. J., Deleva, K., Lynch, T., Kok, G., Ritchie, C. W., Tanzi, R. E. & 4 others, Cappai, R., Masters, C. L., Barnham, K. J. & Bush, A. I., 2008, In : Neuron. 59, p. 43 - 55 13 p.

Research output: Contribution to journalArticleResearchpeer-review

77 Citations (Scopus)

Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials

Creek, D. J., Charman, W. N., Chiu, F. C. K., Prankerd, R. J., Dong, Y., Vennerstrom, J. & Charman, S. A., 2008, In : Antimicrobial Agents and Chemotherapy. 52, 4, p. 1291 - 1296 6 p.

Research output: Contribution to journalArticleResearchpeer-review

27 Citations (Scopus)

Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios

Adi, H., Larson, I. C., Chiou, H., Young, P. M., Traini, D. & Stewart, P. J., 2008, In : Journal of Pharmaceutical Sciences. 97, 1, p. 3140 - 3152 12 p.

Research output: Contribution to journalArticleResearchpeer-review

135 Citations (Scopus)

The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of pegylated poly L-lysine dendrimers

Kaminskas, L. M., Boyd, B. J., Karellas, P., Krippner, G. Y., Lessene, R., Kelly, B. & Porter, C. J., 2008, In : Molecular Pharmaceutics. 5, 3, p. 449 - 463 15 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)
2009
2 Citations (Scopus)

2,5-Dimethyl-2,4-hexadiene induced photodechlorination of 9,10-dichloroanthracene

Saltiel, J., Smothers, W. K., Schanze, K. S., Charman, S. A. & Bonneau, R., 2009, In : Photochemical & Photobiological Sciences. 8, 6, p. 856 - 867 12 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

2nd combined working group and management committee meeting of urine and kidney proteomics COST action 29-30 March 2009, Nafplio, Greece

Vlahou, A., Allmaier, G., Attwood, T., Bongcam-Rudloff, E., Charonis, A., Frokiaer, J., Mischak, H., Schanstra, J., Spasovski, G., Aasberg, A., Allory, Y., Arthur, J., Attwood, T., Banks, R. W., Baumann, M., Benigni, A., Bezerianos, A., Campistol, J. M., Candiano, G., Capasso, G. & 81 others, Carpentier, S., Dadlez, M., Deltas, C., Dijilianov, D., de Zeeuw, D., Decramer, S., Dihazi, H., Domon, B., Endlich, N., d'Alche-Buc, F., D'Haese, P., Edelman, A., Egido, J., El Nahas, M., Farinazzo, A., Fernandez-Llama, P., Feldt-Rasmussen, B., Frokiaer, J., Gansevoort, R. T., Garbis, S., Garin, J., Ghiggeri, G. M., Gimenez, I., Granier, C., Goumenos, D., Haylor, J. L., Hilario, M., Holthofer, H., Kalousis, A., Kaski, S., Knepper, M., Korneti, P., Kossida, S., Langham, R., Loftheim, H., Lopez-Novoa, J., Luider, T., Magni, F., Malats, N., Martin, J. L., Mayrhofer, C., Monsarrat, B., Mueller, G., Nielsen, S., Norling, M., O'Connell, S., Ortiz, J. P. A., Perunicic-Pekovic, G., Planelles, G., Polenakovic, M., Promponas, V., Rasic-Milutinovic, Z., Rehulka, P., Peter, K., Righetti, P. G., Ronco, P., Ryan, M., Sánchez-Carbayo, M., Schanstra, J., Semmes, J., Sheehan, D., Stenman, U. H., Stodkilde-Jorgensen, L., Tasic, V., Theodorescu, D., Thongboonkerd, V., Toncheva, D., Tsillibari, E., Tsiotis, G., Unwin, R., Vanholder, R., Vassilev, D., Vickers, M. E., Verhulst, A., Vilasi, A., Vlahakos, D., Vonk, R., Wright, P. C., Yamamoto, T., Yutaka, Y. & Zielenkiewicz, P., 2009, In : Proteomics - Clinical Applications. 3, 9, p. 1017-1022 6 p.

Research output: Contribution to journalArticleResearchpeer-review

90 Citations (Scopus)

A chitosan-dipotassium orthophosphate hydrogel for the delivery of doxorubicin in the treatment of osteosarcoma

Ta, H. T., Dass, C. R., Larson, I. C., Choong, P. FM. & Dunstan, D. E., 2009, In : Biomaterials. 30, 21, p. 3605 - 3613 9 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy

Ta, H. T., Dass, C. R., Larson, I., Choong, P. F. M. & Dunstan, D. E., Sep 2009, In : Biomaterials. 30, 27, p. 4815-4823 9 p.

Research output: Contribution to journalArticleResearchpeer-review

42 Citations (Scopus)

Advanced fitting algorithms for analysing positron annihilation lifetime spectra

Pascual-Izzara, C., Dong, A., Pas, S. J., Hill, A., Boyd, B. J. & Drummond, C. J., 2009, In : Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. 603, 3, p. 456 - 466 11 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Agglomerate properties and dispersibility changes of salmeterol xinafoate from powders for inhalation after storage at high relative humidity

Das, S. C., Young, P. M., Larson, I. C. & Stewart, P. J., 2009, In : European Journal of Pharmaceutical Sciences. 37, 3-4, p. 442 - 450 9 p.

Research output: Contribution to journalArticleResearchpeer-review

13 Citations (Scopus)

A novel flow through diffusion cell for assessing drug transport across the buccal mucosa in vitro

Lestari, M. L. A. D., Nicolazzo, J. & Finnin, B. C., 2009, In : Journal of Pharmaceutical Sciences. 98, 12, p. 4577 - 4588 12 p.

Research output: Contribution to journalArticleResearchpeer-review

31 Citations (Scopus)
Open Access
25 Citations (Scopus)

Brain penetration of colistin in mice assessed by a novel high-performance liquid chromatographic technique

Jin, L., Li, J., Nation, R. L. & Nicolazzo, J., 2009, In : Antimicrobial Agents and Chemotherapy. 53, 10, p. 4247 - 4251 5 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

Characterization of lipophilic drug binding to rat intestinal fatty acid binding protein

Velkov, T., Hughes, M. L. R., Horne, H. J., Simpson, J. S., Porter, C. J. & Scanlon, M., 2009, In : Molecular and Cellular Biochemistry. 326, 1-2, p. 87 - 95 9 p.

Research output: Contribution to journalArticleResearchpeer-review

49 Citations (Scopus)

Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system

Ta, H. T., Han, H., Larson, I. C., Dass, C. R. & Dunstan, D., 2009, In : International Journal of Pharmaceutics. 371, 1-2, p. 134 - 141 8 p.

Research output: Contribution to journalArticleResearchpeer-review

23 Citations (Scopus)

CYT997: a novel orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo

Burns, C., Fantino, E., Phillips, I. D., Su, S., Harte, M., Bukczynska, P. E., Frazzetto, M., Joffe, M., Kruszelnicki, I., Wang, B., Wang, Y., Wilson, N., Dilley, R. J., Wan, S. S., Charman, S. A., Shackleford, D., Fida, R., Malcontenti-Wilson, C. & Wilks, A. F., 2009, In : Molecular Cancer Therapeutics. 8, 11, p. 3036 - 3045 10 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Discovery of CYT997: a structurally novel orally active microtubule targeting agent

Burns, C., Harte, M., Bu, X., Fantino, E., Joffe, M., Sikanyika, H., Su, S., Tranberg, C. E., Wilson, N., Charman, S. A., Shackleford, D. & Wilks, A. F., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4639 - 4642 4 p.

Research output: Contribution to journalArticleResearchpeer-review

22 Citations (Scopus)

Drug agglomeration and dissolution - What is the influence of powder mixing?

Kale, K. P., Hapgood, K. & Stewart, P. J., 2009, In : European Journal of Pharmaceutics and Biopharmaceutics. 72, 1, p. 156 - 164 9 p.

Research output: Contribution to journalArticleResearchpeer-review

34 Citations (Scopus)

Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2)

Nicolazzo, J. & Katneni, K., 2009, In : Current Topics in Medicinal Chemistry. 9, 2, p. 130 - 147 18 p.

Research output: Contribution to journalArticleResearchpeer-review

11 Citations (Scopus)

GABAergic striatal neurons exhibit caspase-independent, mitochondrially mediated programmed cell death

Diwakarla, S., Mercer, L. D., Kardashsyan, L., Chu, P. W. Y., Shin, Y. S., Lau, C. L., Hughes, M. L. R., Nagley, P. & Beart, P. M., 2009, In : Journal of Neurochemistry. 109, Suppl 1, p. 198 - 206 9 p.

Research output: Contribution to journalArticleResearchpeer-review

150 Citations (Scopus)

Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice

Gujjar, R., Marwaha, A., El Mazouni, F., White, J., White, K. L., Creason, S., Shackleford, D., Baldwin, J., Charman, W. N., Buckner, F. S., Charman, S. A., Rathod, P. & Phillips, M., 2009, In : Journal of Medicinal Chemistry. 52, 7, p. 1864 - 1872 9 p.

Research output: Contribution to journalArticleResearchpeer-review