Research Output 1975 2019

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1998
227 Citations (Scopus)

Polycation-DNA complexes for gene delivery: A comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids

Pouton, C. W., Lucas, P., Thomas, B. J., Uduehi, A. N., Milroy, D. A. & Moss, S. H., 30 Apr 1998, In : Journal of Controlled Release. 53, 1-3, p. 289-299 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids: J Control Release

Pouton, C. W., Lucas, P., Thomas, B. J., Uduehi, A. N., Milroy, D. A. & Moss, S. H., 1998, In : Journal of Controlled Release. 53, p. 289-299 11 p.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Propranolol elimination by right and left fetal liver: Studies in the intact isolated perfused fetal sheep liver

Ring, J. A., Ghabrial, H., Ching, M. S., Shulkes, A., Smallwood, R. A. & Morgan, D. J., 1998, In : Journal of Pharmacology and Experimental Therapeutics. p. 535 - 541 7 p.

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Relationships among liver and kidney volumes, lean body mass and drug clearance

Narawatne, S., Brien, J-A. E., Seeman, E., Fabiny, R., Zalcberg, J. R., Cosolo, W., Angus, P. W. & Morgan, D. J., 1998, In : British Journal of Clinical Pharmacology. p. 447 - 452 6 p.

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)

The application of capillary electrophoresis for monitoring effects of excipients on protein conformation

McIntosh, K. A., Charman, W. N. & Charman, S. A., Feb 1998, In : Journal of Pharmaceutical and Biomedical Analysis. 16, 6, p. 1097-1105 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Theme title: Transport of macromolecules and viruses - Preface: Advanced Drug Delivery Reviews

Pouton, C. & Seymour, L. W., 1998, In : Advanced Drug Delivery Reviews. 34, p. 1-2 2 p.

Research output: Contribution to journalArticleResearchpeer-review

33 Citations (Scopus)

Transdermal delivery of estradiol in postmenopausal women with a novel topical aerosol

Morgan, T. M., O'Sullivan, H. M. M., Reed, B. L. & Finnin, B. C., 1998, In : Journal of Pharmaceutical Sciences. p. 1226 - 1228 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

A novel prodrug approach for tertiary amines.3. In vivo evaluation of two N-phosphonocoxymethyl prodrugs in rats and dogs

Krise, J. P., Charman, W. N., Charman, S. A. & Stella, V. J., 1999, In : Journal of Pharmaceutical Sciences. p. 928 - 932 5 p.

Research output: Contribution to journalArticleResearchpeer-review

5 Citations (Scopus)

Application of a loading wash-out method for investigating the hepatocellular efflux of a hepatically-generated metabolite, morphine-3-glucuronide

Evans, A. M., O'Brien, J. & Nation, R. L., 1 Jan 1999, In : Journal of Pharmacy and Pharmacology. 51, 11, p. 1289-1297 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cationic lipid-mediated transfection of differentiated Caco-2 cells: a filter culture model of gene delivery to a polarized epithelium: Pharm Res

Uduehi, A. N., Moss, S. H., Nuttall, J. & Pouton, C. W., 1999, In : Pharmaceutical Research. 16, p. 1805-1811 7 p.

Research output: Contribution to journalArticleResearchpeer-review

60 Citations (Scopus)

Clonidine and cardiac surgery: Haemodynamic and metabolic effects, myocardial ischaemia and recovery

Myles, P. S., Hunt, J. O., Holdgaard, H. O., McRae, R., Buckland, M. R., Moloney, J., Hall, J., Bujor, M. A., Esmore, D. S., Davis, B. B. & Morgan, D. J., 1999, In : Anaesthesia and intensive care. p. 137 - 147 11 p.

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Comparative effects of oxygen supplementation of theophylline and acetaminophen clearance in human cirrhosis

Froomes, P. R. A., Morgan, D. J., Smallwood, R. A. & Angus, P. W., 1999, In : Gastroenterology. p. 915 - 920 6 p.

Research output: Contribution to journalArticleResearchpeer-review

57 Citations (Scopus)

Determination of lamotrigine in human plasma by high-performance liquid chromatography

Angelis-Stoforidis, P., Morgan, D. J., O'Brien, T. J. & Vajda, F. J. E., 30 Apr 1999, In : Journal of Chromatography B: Biomedical Sciences and Applications. 727, 1-2, p. 113-118 6 p.

Research output: Contribution to journalArticleResearchpeer-review

18 Citations (Scopus)
41 Citations (Scopus)

Drug delivery: A key factor in realising the full therapeutic potential of drugs

Charman, W. N., Chan, H-K., Finnin, B. C. & Charman, S. A., 1999, In : Drug Development Research. 46, 3-4, p. 316-327 12 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Effect of cirrhosis on sulphation by the isolated perfused rat liver

Choo, E. F., Angus, P. W. & Morgan, D. J., 1999, In : Journal of Hepatology. p. 498 - 502 5 p.

Research output: Contribution to journalArticleResearchpeer-review

88 Citations (Scopus)

Fetal hepatic drug elimination

Ring, J. A., Ghabrial, H., Ching, M. S., Smallwood, R. A. & Morgan, D. J., 1999, In : Pharmacology and Therapeutics. p. 429 - 445 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Gene transfer using a bifunctional peptide

Nwachuku, J. N., Ashford, M. & Pouton, C. W., 1 Jan 1999, In : Proceedings of the Controlled Release Society. 26, p. 531-532 2 p.

Research output: Contribution to journalArticleResearchpeer-review

28 Citations (Scopus)

Hepatic disposition of the acyl glucuronide 1-O-gemfibrozil-β-D- glucuronide: Effects of dibromosulfophthalein on membrane transport and aglycone formation

Sabordo, L., Sallustio, B. C., Evans, A. M. & Nation, R. L., 1 Feb 1999, In : Journal of Pharmacology and Experimental Therapeutics. 288, 2, p. 414-420 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Mechanisms controlling diffusion and release of model proteins through and from partially esterified hyaluronic acid membranes

Simon, L. D., Stella, V. J., Charman, W. N. & Charman, S. A., 20 Sep 1999, In : Journal of Controlled Release. 61, 3, p. 267-279 13 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

Organ perfusion techniques in drug development

Stretch, G. L., Nation, R. L., Evans, A. M. & Milne, R. W., 14 Jun 1999, In : Drug Development Research. 46, 3-4, p. 292-301 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis of porphyrin alpha,omega-bis(methylamino)peptide constructs: New Journal of Chemistry

Matthews, S. E., Pouton, C. W. & Threadgill, M. D., 1999, In : New Journal of Chemistry. 23, p. 1087-1096 10 p.

Research output: Contribution to journalArticleResearchpeer-review

8 Citations (Scopus)

Synthesis of porphyrin α,ω-bis(methylamino)peptide constructs

Matthews, S. E., Pouton, C. W. & Threadgill, M. D., 1 Jan 1999, In : New Journal of Chemistry. 23, 11, p. 1087-1096 10 p.

Research output: Contribution to journalArticleResearchpeer-review

205 Citations (Scopus)

Transdermal penetration enhancers: Applications, limitations, and potential

Finnin, B. C. & Morgan, T. M., 1999, In : Journal of Pharmaceutical Sciences. p. 955 - 958 4 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Uptake and excretion of sodium taurocholate by the isolated perfused neonatal sheep liver

Gow, P. J., Treepongkaruna, S., Ching, M. S., Ghabrial, H., Shulkes, A., Smallwood, R. A. & Morgan, D. J., 1999, In : Journal of Pharmaceutical Sciences. p. 445 - 449 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Variation in the diffusion and release of ribonuclease through and from esterified hyaluronic acid membranes: Effect of changes in matrix characteristics

Simon, L. D., Stella, V. J., Charman, W. N. & Charman, S. A., 27 Aug 1999, In : Journal of Controlled Release. 61, 1-2, p. 159-164 6 p.

Research output: Contribution to journalArticleResearchpeer-review

2000

A biodegradable multiblock co-polymer derived from an alpha, omega-bis(methylamino)peptide and an alpha, omega-bis(oxiranylmethyl)poly(ethylene glycol): J Control Release

Matthews, S. E., Pouton, C. W. & Threadgill, M. D., 2000, In : Journal of Controlled Release. 67, p. 129-139 11 p.

Research output: Contribution to journalArticleResearchpeer-review

12 Citations (Scopus)

A biodegradable multiblock co-polymer derived from an α,ω-bis(methylamino)peptide and an α,ω-bis(oxiranylmethyl)poly(ethylene glycol)

Matthews, S. E., Pouton, C. W. & Threadgill, M. D., 3 Jul 2000, In : Journal of Controlled Release. 67, 2-3, p. 129-139 11 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Conjugation of para-nitrophenol by the isolated perfused neonatal sheep liver

Gow, P. J., Ghabrial, H., Treepongkaruna, S., Shulkes, A., Smallwood, R. A., Morgan, D. J. & Ching, M. S., 2000, In : Journal of Pharmaceutical Sciences. p. 36 - 44 9 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Disposition of l-carnitine and its short-chain esters, acetyl-l-carnitine and propionyl-l-carnitine, in the rat isolated perfused liver

Evans, A. M., Mancinelli, A., Longo, A. & Nation, R. L., 19 Dec 2000, In : Drug Metabolism and Disposition. 28, 12, p. 1401-1404 4 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Effect of uranyl nitrate-induced renal failure on morphine disposition and antinociceptive response in rats

Van Crugten, J. T., Somogyi, A. A. & Nation, R. L., 1 Jan 2000, In : Clinical and Experimental Pharmacology and Physiology. 27, 1-2, p. 74-79 6 p.

Research output: Contribution to journalArticleResearchpeer-review

84 Citations (Scopus)

Hepatic Disposition of Electrophilic Acyl Glucuronide Conjugates

Sallustio, B. C., Sabordo, L., Evans, A. M. & Nation, R. L., 1 Jan 2000, In : Current Drug Metabolism. 1, 2, p. 163-180 18 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Hepatic disposition of the acyl glucuronide 1-O-gemfibrozil-β-D-glucuronide: Effects of clofibric acid, acetaminophen, and acetaminophen glucuronide

Sabordo, L., Sallustio, B. C., Evans, A. M. & Nation, R. L., 16 Oct 2000, In : Journal of Pharmacology and Experimental Therapeutics. 295, 1, p. 44-50 7 p.

Research output: Contribution to journalArticleResearchpeer-review

15 Citations (Scopus)

Impaired elimination of propranolol due to right heart failure:Drug clearance in the isolated liver and its relationship to intrinsic metabolic capacity

Ng, C. Y., Ghabrial, H., Morgan, D. J., Ching, M. S., Smallwood, R. A. & Angus, P. W., 2000, In : Drug Metabolism and Disposition. p. 1217 - 1221 5 p.

Research output: Contribution to journalArticleResearchpeer-review

187 Citations (Scopus)

Lipids, lipophilic drugs,and oral drug delivery-Some emerging concepts

Charman, W. N., 2000, In : Journal of Pharmaceutical Sciences. p. 967 - 978 12 p.

Research output: Contribution to journalArticleResearchpeer-review

168 Citations (Scopus)

Lymphatic transport of proteins after subcutaneous administration

Porter, C. J. H. & Charman, S. A., Mar 2000, In : Journal of Pharmaceutical Sciences. 89, 3, p. 297-310 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Multicentre pilot study of a standard aproach to document clinical pharmacy activity

Dooley, M., McLennan, D. N., Galbraith, K. J. & Burgess, N. G., 2000, In : Australian Journal of Hospital Pharmacy. p. 150 - 156 7 p.

Research output: Contribution to journalArticleResearchpeer-review

16 Citations (Scopus)

National survey of clinical activity documentation practices

McLennan, D. N. & Dooley, M., 2000, In : Australian Journal of Hospital Pharmacy. p. 6 - 9 4 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Neonatal hepatic propranolol elimination:Studies in the isolated perfused neonatal sheep liver

Gow, P. J., Treepongkaruna, S., Ghabrial, H., Shulkes, A., Smallwood, R. A., Morgan, D. J. & Ching, M. S., 2000, In : Journal of Pharmaceutical Sciences. p. 586 - 593 8 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Pharmacokinetics of L-carnitine in patients with end-stage renal disease undergoing long-term hemodialysis

Evans, A. M., Faull, R., Fornasini, G., Lemanowicz, E. F., Longo, A., Pace, S. & Nation, R. L., 5 Oct 2000, In : Clinical Pharmacology and Therapeutics. 68, 3, p. 238-249 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Polyamine-Poly(ethylene-glycol) constructs as potential novel DNA-binding vectors for applications in gene therapy of cancer. Clinical Cancer Research

Garrett, S. W., Davies, O. R., Milroy, D. A., Wood, P. J., Pouton, C. W. & Threadgill, M. D., 2000, In : Clinical Cancer Research. 6, p. 4569s-4569s

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Production of an enterotoxin by a gastro-enteritis-associated Aeromonas strain

Trower, C. J., Abo, S., Majeed, K. & Von Itzstein, M., 2000, In : Journal of Medical Microbiology. p. 121 - 126 6 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Right heart failure impairs hepatic elimination of p-nitrophenol without inducing changes in content or latency of hepatic UDP-glucuronosyltransferases

Ng, C. Y., Ghabrial, H., Morgan, D. J., Ching, M. S., Smallwood, R. A. & Angus, P. W., 2000, In : Journal of Pharmacology and Experimental Therapeutics. p. 830 - 835 6 p.

Research output: Contribution to journalArticleResearchpeer-review

55 Citations (Scopus)

Solvation descriptors for pesticides from the solubility of solids: diuron as an example

Laverty, C. E., Abraham, M. H., Acree Jnr, W. E., De Fina, K. M. & Sharp, T. L., 2000, In : Pest Management Science. 56, 12, p. 1043 - 1053 11 p.

Research output: Contribution to journalArticleResearchpeer-review

70 Citations (Scopus)

Systemic availability and lymphatic transport of human growth hormone administered by subcutaneous injection

Charman, S. A., Segrave, A. M., Edwards, G. A. & Porter, C. J. H., Feb 2000, In : Journal of Pharmaceutical Sciences. 89, 2, p. 168-177 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2001
82 Citations (Scopus)

A conscious dog model for assessing the absorption, enterocyte-based metabolism, and intestinal lymphatic transport of halofantrine

Khoo, S-M., Edwards, G. A., Porter, C. J. H. & Charman, W. N., 2001, In : Journal of Pharmaceutical Sciences. 90, 10, p. 1599 - 1607 9 p.

Research output: Contribution to journalArticleResearchpeer-review