Research Output 1975 2019

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2009

Probing the fibrate binding specificity of rat liver fatty acid binding protein

Chuang, S., Velkov, T., Horne, H. J., Wielens, J., Chalmers, D. K., Porter, C. J. & Scanlon, M., 2009, In : Journal of Medicinal Chemistry. 52, 17, p. 5344 - 5355 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Short-term changes in drug agglomeration within interactive mixtures following blending

Andreou, J., Stewart, P. & Morton, D., 2009, In : International Journal of Pharmaceutics. 372, 1-2, p. 1 - 11 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Spiroadamantyl 1,2,4-trioxolane, 1,2,4-trioxane, and 1,2,4-trioxepane pairs: Relationship between peroxide bond iron(II) reactivity, heme alkylation efficiency, and antimalarial activity

Wang, X., Creek, D. J., Schiaffo, C. E., Dong, Y., Chollet, J., Scheurer, C., Wittlin, S., Charman, S. A., Dussault, P. H., Wood, J. K. & Vennerstrom, J., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4542 - 4545 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Stability of peroxide antimalarials in the presence of human hemoglobin

Creek, D. J., Ryan, E., Charman, W. N., Chiu, F. C. K., Prankerd, R., Vennerstrom, J. & Charman, S. A., 2009, In : Antimicrobial Agents and Chemotherapy. 53, 8, p. 3496 - 3500 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Stimuli responsive liquid crystals provide 'on-demand' drug delivery in vitro and in vivo

Fong, W. K., Hanley, T. L. & Boyd, B. J., 2009, In : Journal of Controlled Release. 135, 3, p. 218 - 226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Surface energy changes and their relationship with the dispersibility of salmeterol xinafoate powders for inhalation after storage at high RH

Das, S. C., Larson, I. C., Young, P. M. & Stewart, P. J., 2009, In : European Journal of Pharmaceutical Sciences. 38, 4, p. 347 - 354 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The role of force control agents in high-dose dry powder inhaler formulations

Begat, P., Morton, D. A. V., Shur, J., Kippax, P., Staniforth, J. N. & Price, R., 2009, In : Journal of Pharmaceutical Sciences. 98, 8, p. 2770 - 2783 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2010

Bicontinuous cubic liquid crystals as sustained delivery systems for peptides and proteins

Rizwan, S., Boyd, B., Rades, T. & Hook, S., 2010, In : Expert Opinion on Drug Delivery. 7, 10, p. 1133 - 1144 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Brain uptake of diazepam and phenytoin in a genetic animal model of absence epilepsy

Nicolazzo, J., Steuten, J. A., Charman, S. A., Taylor, N., Davies, P. & Petrou, S., 2010, In : Clinical and Experimental Pharmacology and Physiology. 37, p. 647 - 649 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Discovery of novel benzo[ a ]phenoxazine SSJ-183 as a drug candidate for malaria

Ge, J-F., Arai, C., Yang, M., Bakar, A., Lu, J., Ismail, N. S. M., Wittlin, S., Kaiser, M., Brun, R., Charman, S. A., Nguyen, T., Morizzi, J., Itoh, I. & Ihara, M., 2010, In : A C S Medicinal Chemistry Letters. 1, 7, p. 360 - 364 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Diverse ordered 3D nanostructured amphiphile self-assembly materials found in protic ionic liquids

Mulet, X., Kennedy, D., Greaves, T., Waddington, L., Hawley, A., Kirby, N. & Drummond, C., 2010, In : Journal of Physical Chemistry Letters. 1, 18, p. 2651 - 2654 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution

Dube, A., Ng, K., Nicolazzo, J. & Larson, I. C., 2010, In : Food Chemistry. 122, p. 662 - 667 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of electroacupuncture on the third lumbar transverse process syndrome: A randomized controlled trial

Miao, E. & Miao, M., 2010, In : Medical Acupuncture. 22, 4, p. 249 - 255 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Efficacy of antimicrobial polymer coatings in an animal model of bacterial infection associated with foreign body implants

Hart, E., Azzopardi, K., Taing, H., Graichen, F., Jeffery, J., Mayadunne, R., Wickramaratna, M., OShea, M., Nijagal, B., Watkinson, R., OLeary, S., Finnin, B., Tait, R. & Robins-Browne, R., 2010, In : Journal of Antimicrobial Chemotherapy. 65, 5, p. 974 - 980 7 p.

Research output: Contribution to journalArticleResearchpeer-review

High throughput preparation and characterisation of amphiphilic nanostructured nanoparticulate drug delivery vehicles

Mulet, X., Kennedy, D., Conn, C., Hawley, A. & Drummond, C., 2010, In : International Journal of Pharmaceutics. 395, 1-2, p. 290 - 297 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Impact of chlorpromazine self-association on its apparent binding constants with cyclodextrins: Effect of SBE7-beta-CD on the disposition of chlorpromazine in the rat

McIntosh, M. P., Leong, N., Katneni, K., Morizzi, J., Shackleford, D. M. & Prankerd, R. J., 2010, In : Journal of Pharmaceutical Sciences. 99, 7, p. 2999 - 3008 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach

Zhou, Q., Qu, L., Larson, I. C., Stewart, P. J. & Morton, D. A. V., 2010, In : International Journal of Pharmaceutics. 394, 1-Feb, p. 50 - 59 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Improving powder flow properties of a cohesive lactose monohydrate powder by intensive mechanical dry coating

Zhou, Q., Armstrong, B., Larson, I. C., Stewart, P. J. & Morton, D. A. V., 2010, In : Journal of Pharmaceutical Sciences. 99, 2, p. 969 - 981 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in biabetic mice

Urban, M., Li, C., Yu, C., Lu, Y., Krise, J., McIntosh, M. P., Rajewski, R. A., Blagg, B. & Dobrowsky, R. T., 2010, In : ASN Neuro. 2, 4, p. 189 - 199 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Ligand-enhanced expression and in-cell assay of human peroxisome proliferator-activated receptor alpha ligand binding domain

Velkov, T., Rimmer, K. & Headey, S., 2010, In : Protein Expression and Purification. 70, 2, p. 260 - 269 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Magnesium stearate increases salbutamol sulphate dispersion: what is the mechanism?

Tay, T., Das, S. C. & Stewart, P. J., 2010, In : International Journal of Pharmaceutics. 383, p. 62 - 69 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Monodisperse nonionic phytanyl ethylene oxide surfactants: High throughput lyotropic liquid crystalline phase determination and the formation of liposomes, hexosomes and cubosomes

Fong, C., Weerawardena, A., Sagnella, S., Mulet, X., Waddington, L., Krodkiewska, I. & Drummond, C., 2010, In : Soft Matter. 6, 19, p. 4727 - 4741 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanostructured nonionic thymidine nucleolipid self-assembly materials

Mulet, X., Kaasgaard, T., Conn, C., Waddington, L., Kennedy, D., Weerawardena, A. & Drummond, C., 2010, In : Langmuir: the ACS journal of surfaces and colloids. 26, 23, p. 18415 - 18423 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Nonequilibrium effects in self-assembled mesophase materials: unexpected supercooling effects for cubosomes and hexosomes

Dong, C. Y-D., Tilley, A. J., Larson, I. C., Lawrence, J., Amenitsch, H., Rappolt, M., Hanley, T. L. & Boyd, B. J., 2010, In : Langmuir: the ACS journal of surfaces and colloids. 26, 11, p. 9000 - 9010 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Plasmonic nanorods provide reversible control over nanostructure of self-assembled drug delivery materials

Fong, W. K., Hanley, T. L., Thierry, B., Kirby, N. & Boyd, B. J., 2010, In : Langmuir: the ACS journal of surfaces and colloids. 26, 9, p. 6136 - 6139 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Preclinical comparison of intravenous melphalan pharmacokinetics administered in formulations containing either (SBE)7m-beta-cyclodextrin or a co-solvent system

Koltun, M., Morizzi, J., Katneni, K., Charman, S. A., Shackleford, D. & McIntosh, M. P., 2010, In : Biopharmaceutics and Drug Disposition. 31, 8-9, p. 450 - 454 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Self-assembly behavior of colistin and its prodrug colistin methanesulfonate: implications for solution stability and solubilization

Wallace, S. J., Li, J., Nation, R. L., Prankerd, R. J., Velkov, T. & Boyd, B. J., 2010, In : Journal of Physical Chemistry B. 114, p. 4836 - 4840 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Silica nanoparticles to control the lipase-mediated digestion of lipid-based oral delivery systems

Tan, A., Simovic, S., Davey, A., Rades, T., Boyd, B. J. & Prestidge, C. A., 2010, In : Molecular Pharmaceutics. 7, 2, p. 522 - 532 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Sulfonamide linked neoglycoconjugates-A new class of inhibitors for cancer-associated carbonic anhydrases

Lopez, M., Bornaghi, L. F., Innocenti, A., Vullo, D., Charman, S. A., Supuran, C. T. & Poulsen, S-A., 2010, In : Journal of Medicinal Chemistry. 53, p. 2913 - 2926 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Synthesis and Biological Evaluation of Polysulfated Oligosaccharide Glycosides as Inhibitors of Angiogenesis and Tumor Growth

Johnstone, K. D., Karoli, T., Liu, L., Dredge, K., Copeman, E., Li, C. P., Davis, K., Hammond, E., Bytheway, I., Kostewicz, E. S., Chiu, F. C. K., Shackleford, D., Charman, S. A., Charman, W. N., Harenberg, J., Gonda, T. & Ferro, V., 2010, In : Journal of Medicinal Chemistry. 53, 4, p. 1686 - 1699 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation?

Trevaskis, N., Charman, W. & Porter, C., 2010, In : Molecular Pharmaceutics. 7, 6, p. 2297 - 2309 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The buccal mucosa as an alternative route for the systemic delivery of risperidone

Heemstra, L. B., Finnin, B. C. & Nicolazzo, J., 2010, In : Journal of Pharmaceutical Sciences. 99, 11, p. 4584 - 4592 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The comparative antimalarial properties of weak base and neutral synthetic ozonides

Tang, Y., Wittlin, S., Charman, S. A., Chollet, J., Chiu, F. C. K., Morizzi, J., Johnson, L., Santo Tomas, J., Scheurer, C., Snyder, C., Zhou, L., Dong, Y., Charman, W. N., Matile, H., Urwyler, H., Dorn, A. & Vennerstrom, J., 2010, In : Bioorganic and Medicinal Chemistry Letters. 20, 2, p. 563 - 566 4 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of sucrose and salts in combination on the drug release behaviour of an HPMC matrix

Williams, H., Ward, R., Hardy, I. & Melia, C., 2010, In : European Journal of Pharmaceutics and Biopharmaceutics. 76, 3, p. 433 - 436 4 p.

Research output: Contribution to journalArticleOther

The role of the intestinal lymphatics in the absorption of two highly lipophilic cholesterol ester transfer protein inhibitors (CP524,515 and CP532,623)

Trevaskis, N., McEvoy, C. L., McIntosh, M. P., Edwards, G. A., Shanker, R., Charman, W. N. & Porter, C. J., 2010, In : Pharmaceutical Research. 27, p. 878 - 893 16 p.

Research output: Contribution to journalArticleResearchpeer-review

The structure - activity relationship of the antimalarial ozonide arterolane (OZ277)

Dong, Y., Wittlin, S., Sriraghavan, K., Chollet, J., Charman, S. A., Charman, W. N., Scheurer, C., Urwyler, H., Santo Tomas, J., Snyder, C., Creek, D. J., Morizzi, J., Koltun, M., Matile, H., Wang, X., Padmanilayam, M., Tang, Y., Dorn, A., Brun, R. & Vennerstrom, J., 2010, In : Journal of Medicinal Chemistry. 53, p. 481 - 491 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Transport of drugs across the blood-brain barrier in Alzheimer's disease

Nicolazzo, J. & Mehta, D., 2010, In : Therapeutic Delivery. 1, 4, p. 595 - 611 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Ultrasonic nebulization platforms for pulmonary drug delivery

Yeo, L., Friend, J., McIntosh, M. P., Meeusen, E. & Morton, D., 2010, In : Expert Opinion on Drug Delivery. 7, 6, p. 663 - 679 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Understanding lactose behaviour during storage by monitoring surface energy change using inverse gas chromatography

Das, S., Larson, I., Young, P. & Stewart, P., Mar 2010, In : Dairy Science Technologies. 90, 2-3, p. 271-285 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders

Zhou, Q., Armstrong, B., Larson, I., Stewart, P. & Morton, D., 2010, In : European Journal of Pharmaceutical Sciences. 40, 5, p. 412 - 421 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility

Warren, D., Benameur, H., Porter, C. J. & Pouton, C. W., 2010, In : Journal of Drug Targeting. 18, 10, p. 704 - 731 28 p.

Research output: Contribution to journalArticleResearchpeer-review

2011

Activities of colistin- and minocycline-based combinations against extensive drug resistant acinetobacter baumannii isolates from intensive care unit patients

Liang, W., Liu, X-F., Huang, J., Zhu, D., Li, J. & Zhang, J., 2011, In : BMC Infectious Diseases. 11, 109, p. e1 - e7 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Adsorption of nonlamellar nanostructured liquid-crystalline particles to biorelevant surfaces for improved delivery of bioactive compounds.

Dong, Y., Larson, I., Barnes, T., Prestidge, C. & Boyd, B., 2011, In : ACS Applied Materials and Interfaces. 3, 5, p. 1771 - 1780 10 p.

Research output: Contribution to journalArticleResearchpeer-review