Research Output 1975 2019

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2008

Evaluation of the impact of surfactant digestion on the bioavailability of Danazol after oral administration of lipidic self-emulsifying formulations to dogs

Cuine, J., McEvoy, C. L., Charman, W. N., Pouton, C. W., Edwards, G. A., Benameur, H. & Porter, C. J., 2008, In : Journal of Pharmaceutical Sciences. 97, 2, p. 995 - 1012 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Formulation of lipid-based delivery systems for oral administration: Materials, methods and strategies

Pouton, C. W. & Porter, C. J., 2008, In : Advanced Drug Delivery Reviews. 60, 6, p. 625 - 637 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Generic construction of single component particles that elicit humoural and cellular immune responses without the need for adjuvants

White, P. J., Anastasopoulos, F., Church, J. E., Kuo, C-Y. J., Boyd, B. J., Hickey, P. LC., Sze Tu, L., Burns, P., Lew, A. M., Heath, W. R., Davey, G. M. & Pouton, C. W., 2008, In : Vaccine. 26, 52, p. 6824 - 6831 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Genistein- and daidzein 7-O-beta-D-glucuronic acid retain the ability to inhibit copper-mediated lipid oxidation of low density lipoprotein

Kgomotso, T., Chiu, F. C. K. & Ng, K., 2008, In : Molecular Nutrition and Food Research. 52, 12, p. 1457 - 1466 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Impurities in commercial phytantriol significantly alter its lyotropic liquid-crystalline phase behavior

Dong, Y-D., Dong, A., Larson, I. C., Rappolt, M., Amenitsch, H., Hanley, T. L. & Boyd, B. J., 2008, In : Langmuir: the ACS journal of surfaces and colloids. 24, 13, p. 6998 - 7003 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update

Trevaskis, N., Charman, W. N. & Porter, C. J., 2008, In : Advanced Drug Delivery Reviews. 60, 6, p. 702 - 716 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Navigating transdermal diffusion with multiphoton fluorescence lifetime imaging

Bird, D. K., Schneider, A. L., Watkinson, A. C., Finnin, B. C. & Smith, T. A., 2008, In : Journal of Microscopy. 230, 1, p. 61 - 69 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Ni2+-Based Immobilized Metal Ion Affinity Chromatography of Lactose Operon Repressor Protein from Escherichia Coli

Velkov, T., Jones, A. & Lim, M. L. R., 2008, In : Preparative Biochemistry & Biotechnology. 38, 4, p. 422 - 441 20 p.

Research output: Contribution to journalArticleResearchpeer-review

Past and future evolution in colloidal drug delivery systems

Boyd, B. J., 2008, In : Expert Opinion on Drug Delivery. 5, 1, p. 69 - 85 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetics and brain uptake of AM-36, a novel neuroprotective agent, following intravenous administration to rats

Nicolazzo, J., Nguyen, T. T., Katneni, K., Steuten, J. A., Smith, G. D., Jarrott, B., Callaway, J. K. & Charman, S. A., 2008, In : Journal of Pharmacy and Pharmacology. 60, 2, p. 171 - 178 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacy Education in the Context of Australian Practice

Marriott, J. L., Nation, R. L., Roller, L., Costelloe, M. T., Galbraith, K. J., Stewart, P. J. & Charman, W. N., 2008, In : American Journal of Pharmaceutical Education. 72, 6, p. 1 - 12 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Preparation and in vitro evaluation of novel lipopeptide transfection agents for efficient gene delivery

Tarwadi, T., Jazayeri, J., Prankerd, R. & Pouton, C. W., 2008, In : Bioconjugate Chemistry. 19, 4, p. 940 - 950 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Rapid restoration of cognition in alzheimer's transgenic mice with 8-hydroxy quinoline analogs is associated with decreased interstitial Abeta

Adlard, P. A., Cherny, R. A., Finklestein, D. I., Gautier, E., Robb, E., Cortes, M., Volitakis, I., Liu, X., Smith, J. P., Perez, K., Laughton, K. M., Lin, Q-X., Charman, S. A., Nicolazzo, J., Wilkins, S. J., Deleva, K., Lynch, T., Kok, G., Ritchie, C. W., Tanzi, R. E. & 4 othersCappai, R., Masters, C. L., Barnham, K. J. & Bush, A. I., 2008, In : Neuron. 59, p. 43 - 55 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Relationship between antimalarial activity and heme alkylation for spiro- and dispiro-1,2,4-trioxolane antimalarials

Creek, D. J., Charman, W. N., Chiu, F. C. K., Prankerd, R. J., Dong, Y., Vennerstrom, J. & Charman, S. A., 2008, In : Antimicrobial Agents and Chemotherapy. 52, 4, p. 1291 - 1296 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Role of agglomeration in the dispersion of salmeterol xinafoate from mixtures for inhalation with differing drug to fine lactose ratios

Adi, H., Larson, I. C., Chiou, H., Young, P. M., Traini, D. & Stewart, P. J., 2008, In : Journal of Pharmaceutical Sciences. 97, 1, p. 3140 - 3152 12 p.

Research output: Contribution to journalArticleResearchpeer-review

The impact of molecular weight and PEG chain length on the systemic pharmacokinetics of pegylated poly L-lysine dendrimers

Kaminskas, L. M., Boyd, B. J., Karellas, P., Krippner, G. Y., Lessene, R., Kelly, B. & Porter, C. J., 2008, In : Molecular Pharmaceutics. 5, 3, p. 449 - 463 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2009

2,5-Dimethyl-2,4-hexadiene induced photodechlorination of 9,10-dichloroanthracene

Saltiel, J., Smothers, W. K., Schanze, K. S., Charman, S. A. & Bonneau, R., 2009, In : Photochemical & Photobiological Sciences. 8, 6, p. 856 - 867 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2nd combined working group and management committee meeting of urine and kidney proteomics COST action 29-30 March 2009, Nafplio, Greece

Vlahou, A., Allmaier, G., Attwood, T., Bongcam-Rudloff, E., Charonis, A., Frokiaer, J., Mischak, H., Schanstra, J., Spasovski, G., Aasberg, A., Allory, Y., Arthur, J., Attwood, T., Banks, R. W., Baumann, M., Benigni, A., Bezerianos, A., Campistol, J. M., Candiano, G., Capasso, G. & 81 othersCarpentier, S., Dadlez, M., Deltas, C., Dijilianov, D., de Zeeuw, D., Decramer, S., Dihazi, H., Domon, B., Endlich, N., d'Alche-Buc, F., D'Haese, P., Edelman, A., Egido, J., El Nahas, M., Farinazzo, A., Fernandez-Llama, P., Feldt-Rasmussen, B., Frokiaer, J., Gansevoort, R. T., Garbis, S., Garin, J., Ghiggeri, G. M., Gimenez, I., Granier, C., Goumenos, D., Haylor, J. L., Hilario, M., Holthofer, H., Kalousis, A., Kaski, S., Knepper, M., Korneti, P., Kossida, S., Langham, R., Loftheim, H., Lopez-Novoa, J., Luider, T., Magni, F., Malats, N., Martin, J. L., Mayrhofer, C., Monsarrat, B., Mueller, G., Nielsen, S., Norling, M., O'Connell, S., Ortiz, J. P. A., Perunicic-Pekovic, G., Planelles, G., Polenakovic, M., Promponas, V., Rasic-Milutinovic, Z., Rehulka, P., Peter, K., Righetti, P. G., Ronco, P., Ryan, M., Sánchez-Carbayo, M., Schanstra, J., Semmes, J., Sheehan, D., Stenman, U. H., Stodkilde-Jorgensen, L., Tasic, V., Theodorescu, D., Thongboonkerd, V., Toncheva, D., Tsillibari, E., Tsiotis, G., Unwin, R., Vanholder, R., Vassilev, D., Vickers, M. E., Verhulst, A., Vilasi, A., Vlahakos, D., Vonk, R., Wright, P. C., Yamamoto, T., Yutaka, Y. & Zielenkiewicz, P., 2009, In : Proteomics - Clinical Applications. 3, 9, p. 1017-1022 6 p.

Research output: Contribution to journalArticleResearchpeer-review

A chitosan-dipotassium orthophosphate hydrogel for the delivery of doxorubicin in the treatment of osteosarcoma

Ta, H. T., Dass, C. R., Larson, I. C., Choong, P. FM. & Dunstan, D. E., 2009, In : Biomaterials. 30, 21, p. 3605 - 3613 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A chitosan hydrogel delivery system for osteosarcoma gene therapy with pigment epithelium-derived factor combined with chemotherapy

Ta, H. T., Dass, C. R., Larson, I., Choong, P. F. M. & Dunstan, D. E., Sep 2009, In : Biomaterials. 30, 27, p. 4815-4823 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Advanced fitting algorithms for analysing positron annihilation lifetime spectra

Pascual-Izzara, C., Dong, A., Pas, S. J., Hill, A., Boyd, B. J. & Drummond, C. J., 2009, In : Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors, and Associated Equipment. 603, 3, p. 456 - 466 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Agglomerate properties and dispersibility changes of salmeterol xinafoate from powders for inhalation after storage at high relative humidity

Das, S. C., Young, P. M., Larson, I. C. & Stewart, P. J., 2009, In : European Journal of Pharmaceutical Sciences. 37, 3-4, p. 442 - 450 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A novel flow through diffusion cell for assessing drug transport across the buccal mucosa in vitro

Lestari, M. L. A. D., Nicolazzo, J. & Finnin, B. C., 2009, In : Journal of Pharmaceutical Sciences. 98, 12, p. 4577 - 4588 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Brain penetration of colistin in mice assessed by a novel high-performance liquid chromatographic technique

Jin, L., Li, J., Nation, R. L. & Nicolazzo, J., 2009, In : Antimicrobial Agents and Chemotherapy. 53, 10, p. 4247 - 4251 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of lipophilic drug binding to rat intestinal fatty acid binding protein

Velkov, T., Hughes, M. L. R., Horne, H. J., Simpson, J. S., Porter, C. J. & Scanlon, M., 2009, In : Molecular and Cellular Biochemistry. 326, 1-2, p. 87 - 95 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Chitosan-dibasic orthophosphate hydrogel: a potential drug delivery system

Ta, H. T., Han, H., Larson, I. C., Dass, C. R. & Dunstan, D., 2009, In : International Journal of Pharmaceutics. 371, 1-2, p. 134 - 141 8 p.

Research output: Contribution to journalArticleResearchpeer-review

CYT997: a novel orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo

Burns, C., Fantino, E., Phillips, I. D., Su, S., Harte, M., Bukczynska, P. E., Frazzetto, M., Joffe, M., Kruszelnicki, I., Wang, B., Wang, Y., Wilson, N., Dilley, R. J., Wan, S. S., Charman, S. A., Shackleford, D., Fida, R., Malcontenti-Wilson, C. & Wilks, A. F., 2009, In : Molecular Cancer Therapeutics. 8, 11, p. 3036 - 3045 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Discovery of CYT997: a structurally novel orally active microtubule targeting agent

Burns, C., Harte, M., Bu, X., Fantino, E., Joffe, M., Sikanyika, H., Su, S., Tranberg, C. E., Wilson, N., Charman, S. A., Shackleford, D. & Wilks, A. F., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 16, p. 4639 - 4642 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Drug agglomeration and dissolution - What is the influence of powder mixing?

Kale, K. P., Hapgood, K. & Stewart, P. J., 2009, In : European Journal of Pharmaceutics and Biopharmaceutics. 72, 1, p. 156 - 164 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2)

Nicolazzo, J. & Katneni, K., 2009, In : Current Topics in Medicinal Chemistry. 9, 2, p. 130 - 147 18 p.

Research output: Contribution to journalArticleResearchpeer-review

GABAergic striatal neurons exhibit caspase-independent, mitochondrially mediated programmed cell death

Diwakarla, S., Mercer, L. D., Kardashsyan, L., Chu, P. W. Y., Shin, Y. S., Lau, C. L., Hughes, M. L. R., Nagley, P. & Beart, P. M., 2009, In : Journal of Neurochemistry. 109, Suppl 1, p. 198 - 206 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in mice

Gujjar, R., Marwaha, A., El Mazouni, F., White, J., White, K. L., Creason, S., Shackleford, D., Baldwin, J., Charman, W. N., Buckner, F. S., Charman, S. A., Rathod, P. & Phillips, M., 2009, In : Journal of Medicinal Chemistry. 52, 7, p. 1864 - 1872 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of storage relative humidity on the dispersion of salmeterol xinafoate powders for inhalation

Das, S. C., Larson, I. C., Young, P. M. & Stewart, P. J., 2009, In : Journal of Pharmaceutical Sciences. 98, p. 1015 - 1027 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of the polydispersity of the added fine lactose on the dispersion of salmeterol xinafoate from mixtures for inhalation

Adi, H., Larson, I. C. & Stewart, P. J., 2009, In : European Journal of Pharmaceutical Sciences. 36, 2-3, p. 265 - 274 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Intestinal lymphatic transport enhances the post-prandial oral bioavailability of a novel cannabinoid receptor agonist via avoidance of first-pass metabolism

Trevaskis, N., Shackleford, D., Charman, W. N., Edwards, G. A., Gardin, A., Appel-Dingemanse, S., Kretz, O., Galli, B. & Porter, C. J., 2009, In : Pharmaceutical Research. 26, 6, p. 1486 - 1495 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Liquid crystalline coated drug particles as a potential route to long acting intravitreal steroids

Tilley, A. J., Morton, D. A. V., Hanley, T. & Boyd, B. J., 2009, In : Current Drug Delivery. 6, 4, p. 322 - 331 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: characterisation, swelling and release kinetics

Rizwan, S. B., Hanley, T., Boyd, B. J., Rades, T. & Hook, S., 2009, In : Journal of Pharmaceutical Sciences. 98, 11, p. 4191 - 4204 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Miniature inhalation therapy platform using surface acoustic wave microfluidic atomization

Qi, A., Friend, J., Yeo, L. Y-M., Morton, D. A. V., McIntosh, M. P. & Spiccia, L., 2009, In : Lab on a Chip. 9, p. 2184 - 2193 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Nanostructure of liquid crystalline matrix determines in vitro sustained release and in vivo oral absorption kinetics for hydrophilic model drugs

Lee, K. W-Y., Nguyen, T-H., Hanley, T. & Boyd, B. J., 2009, In : International Journal of Pharmaceutics. 365, 1-2, p. 190 - 199 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Nonlamellar liquid crystalline nanostructured particles: advances in materials and structure determination

Boyd, B. J., Dong, Y-D. & Rades, T., 2009, In : Journal of Liposome Research. 19, 1, p. 12 - 28 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Oral bioavailability assessment and intestinal lymphatic transport of org 45697 and org 46035, two highly lipophilic novel immunomodulator analogues

Caliph, S. M., Faassen, W. A., Vogel, G. M. & Porter, C. J., 2009, In : Current Drug Delivery. 6, 4, p. 359 - 366 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Overcoming biological barriers to in vivo efficacy of antisense oligonucleotides.

White, P. J., Anastasopoulos, F., Pouton, C. W. & Boyd, B. J., 2009, In : Expert Reviews in Molecular Medicine. 11, e10, p. 1 - 19 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Partly-PEGylated poly-L-lysine dendrimers have reduced plasma stability and circulation times compared with fully PEGylated dendrimers

Kaminskas, L. M., Wu, Z., Barlow, N., Krippner, G. Y., Boyd, B. J. & Porter, C. J. H., 2009, In : Journal of Pharmaceutical Sciences. 98, 10, p. 3871 - 3875 5 p.

Research output: Contribution to journalArticleResearchpeer-review

PEGylation of polylysine dendrimers improves absorption and lymphatic targeting following SC administration in rats

Kaminskas, L. M., Kota, J., McLeod, V. M., Kelly, B. D., Karellas, P. & Porter, C. J., 2009, In : Journal of Controlled Release. 140, 2, p. 108 - 116 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetics and tumor disposition of PEGylated, methotrexate conjugated poly-L-lysine dendrimers

Kaminskas, L. M., Kelly, B. D., McLeod, V. M., Boyd, B. J., Krippner, G. Y., Williams, E. & Porter, C. J., 2009, In : Molecular Pharmaceutics. 6, 4, p. 1190 - 1204 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Phenylaminopyrimidines as inhibitors of Janus kinases (JAKs)

Burns, C., Bourke, D. G., Andrau, L., Bu, X., Charman, S. A., Donohue, A. C., Fantino, E., Farrugia, M., Feutrill, J. T., Joffe, M., Kling, R. M., Kurek, M., Nero, T. L., Nguyen, T., Palmer, J. T., Phillips, I. D., Shackleford, D., Sikanyika, H., Styles, M., Su, S. & 3 othersTreutlein, H. R., Zeng, J. & Wilks, A. F., 2009, In : Bioorganic and Medicinal Chemistry Letters. 19, 20, p. 5887 - 5892 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Positron annihilation lifetime spectroscopy (PALS) as a characterization technique for nanostructured self-assembled amphiphile systems

Dong, A., Pascual-Izzara, C., Pas, S. J., Hill, A., Boyd, B. J. & Drummond, C. J., 2009, In : Journal of Physical Chemistry B. 113, 1, p. 84 - 91 8 p.

Research output: Contribution to journalArticleResearchpeer-review