Research Output 1975 2019

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2006

Efficacy evaluation of an anti-wrinkle formulation

Schneider, A. L., 2006, In : The AustralAsian Journal of Cosmetic Science. 19, 3, p. 22 - 26 5 p.

Research output: Contribution to journalArticleOther

Hexosomes formed from glycerate surfactants-Formulation as a colloidal carrier for irinotecan

Boyd, B. J., Whittaker, D. V., Khoo, S-M. & Davey, G., 2006, In : International Journal of Pharmaceutics. 318, 1-2, p. 154 - 162 9 p.

Research output: Contribution to journalArticleResearchpeer-review

In vitro assessment of the pharmacodynamic properties and the partitioning of OZ277/RBx-11160 in cultures of Plasmodium falciparum

Maerki, S., Brun, R., Charman, S. A., Dorn, A., Matile, H. & Wittlin, S., 2006, In : Journal of Antimicrobial Chemotherapy. 58, 1, p. 52 - 58 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Lymphatic fatty acids in canines dosed with pharmaceutical formulations containing structured triacylglycerols

Holm, R., Porsgaard, T., Porter, C. J. H., Hoy, C-E., Edwards, G. A., Mullertz, A., Kristensen, H. G. & Charman, W. N., 2006, In : European Journal of Lipid Science and Technology. 108, 9, p. 714 - 722 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Lyotropic liquid crystalline phases formed from glycerate surfactants as sustained release drug delivery systems

Boyd, B. J., Whittaker, D. V., Khoo, S-M. & Davey, G., 2006, In : International Journal of Pharmaceutics. 309, 1-2, p. 218 - 226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Methods to assess drug permeability across the blood-brain barrier

Nicolazzo, J. A., Charman, S. A. & Charman, W. N., 2006, In : Journal of Pharmacy and Pharmacology. 58, 3, p. 281 - 293 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Morphology and gelation of thermosensitive xyloglucan hydrogels

Nisbet, D. R., Crompton, K. E., Hamilton, S. D., Shirakawa, S., Prankerd, R. J., Finkelstein, D. I., Horne, M. K. & Forsythe, J. S., 2006, In : Biophysical Chemistry. 121, 1, p. 14 - 20 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Ongoing In Vivo Studies with Cytoskeletal Drugs in Tau Transgenic Mice

Georg, G., McIntosh, M. P., Rajewski, R. A. & Telikepalli, H., 2006, In : Current Alzheimer Research. 3, 3, p. 215 - 219 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach

Katneni, K., Charman, S. A. & Porter, C. J. H., 2006, In : Journal of Pharmaceutical Sciences. 95, 10, p. 2170 - 2185 16 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmakokinetik und pharmakodynamik der β-lactame

Sörgel, F., Bulitta, J. & Landersdorfer, C., 9 Oct 2006, In : Pharmazie in Unserer Zeit. 35, 5, p. 438-451 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Positional isomers of linear sodium dodecyl benzene sulfonate: solubility, self-assembly, and air/water interfacial activity

Ma, J-G., Boyd, B. J. & Drummond, C. J., 2006, In : Langmuir: the ACS journal of surfaces and colloids. 22, 21, p. 8646 - 8654 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase

Ellis, A. G., Doherty, M. M., Walker, F., Weinstock, J., Nerrie, M., Vitali, A., Murphy, R., Johns, T. G., Scott, A. M., Levitski, A., McLachlan, G., Webster, L. K., Burgess, A. W. & Nice, E., 2006, In : Biochemical Pharmacology. 71, p. 1422 - 1434 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Preliminary evaluation of polymer-based drug composite microparticle production by coacervate desolvation with supercritical carbon dioxide

Yasuji, T., Haslam, J., Kajiyama, A., McIntosh, M. P. & Rajewski, R. A., 2006, In : Journal of Pharmaceutical Sciences. 95, 3, p. 581 - 588 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Preparation and purification of desethylamiodarone hydrochloride

Lucas, A. N., Tanol, M., McIntosh, M. P. & Rajewski, R. A., 2006, In : Synthetic Communications. 36, April, p. 3371 - 3376 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The absorption of darbepoetin alfa occurs predominantly via the lymphatics following subcutaneous administration to sheep.

McLennan, D. N., Porter, C. J. H., Edwards, G. A., Heatherington, A. C., Martin, S. W. & Charman, S. A., 2006, In : Pharmaceutical Research. 23, 9, p. 2060 - 2066 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The binding interaction of synthetic ozonide antimalarials with natural and modified beta-cyclodextrins

Perry, C. S., Charman, S. A., Prankerd, R. J., Chiu, F. C. K., Scanlon, M. J., Chalmers, D. K. & Charman, W. N., 2006, In : Journal of Pharmaceutical Sciences. 95, 1, p. 146 - 158 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The lymph lipid precursor pool is a key determinant of intestinal lymphatic drug transport

Trevaskis, N., Porter, C. J. H. & Charman, W. N., 2006, In : Journal of Pharmacology and Experimental Therapeutics. 316, 2, p. 881 - 891 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Tissue uptake of DDT is independent of chylomicron metabolism

Trevaskis, N. L., Tso, P., Rider, T., Charman, W. N., Porter, C. J. H. & Jandacek, R., 2006, In : Archives of Toxicology. 80, 4, p. 196 - 200 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Transport is not rate-limiting in morphine glucuronidation in the single-pass perfused rat liver preparation

Doherty, M. M., Poon, K., Tsang, C. & Pang, K. S., 2006, In : Journal of Pharmacology and Experimental Therapeutics. 317, 2, p. 890 - 900 11 p.

Research output: Contribution to journalArticleResearchpeer-review

2007

A combined spectroscopic and functional MRI investigation of the dorsal anterior cingulate region in opiate addiction

Yücel, M., Lubman, D. I., Harrison, B. J., Fornito, A., Allen, N. B., Wellard, R. M., Roffel, K., Clarke, K., Wood, S. J. & Forman, S. D., 2007, In : Molecular Psychiatry. 12, 7, p. 691 1 p.

Research output: Contribution to journalArticleResearchpeer-review

Adhesion and redistribution of salmeterol xinafoate particles in sugar-based mixtures for inhalation

Adi, H., Larson, I. C. & Stewart, P. J., 2007, In : International Journal of Pharmaceutics. 337, 1-2, p. 229 - 238 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A lipid-based liquid crystalline matrix that provides sustained release and enhanced oral bioavailability for a model poorly water soluble drug in rats

Boyd, B. J., Khoo, S. M., Whittaker, D. V., Davey, G. & Porter, C. J., 2007, In : International Journal of Pharmaceutics. 340, 1-2, p. 52 - 60 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM)

Rizwan, S. B., Dong, Y-D., Boyd, B. J., Rades, T. & Hook, S., 2007, In : Micron. 38, p. 478 - 485 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of fibrinogen adsorption onto glass microcapillary surfaces by ELISA

Salim, M., 2007, In : Lab on a Chip. 7, p. 64-70

Research output: Contribution to journalArticleResearchpeer-review

Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers)

Dong, Y., Creek, D. J., Chollet, J., Matile, H., Charman, S. A., Wittlin, S., Woods, J. H. & Vennerstrom, J., 2007, In : Antimicrobial Agents and Chemotherapy. 51, 8, p. 3033 - 3035 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhancement of the dissolution of indomethacin in interactive mixtures using added fine lactose

Allahham, A. & Stewart, P. J., 2007, In : European Journal of Pharmaceutics and Biopharmaceutics. 67, 3, p. 732 - 742 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Evaluation of mean arterial blood pressure, heart rate, and sympathetic nerve activity in rabbits after administration of two formulations of etomidate

McIntosh, M. P., Narita, H., Kameyama, Y., Rajewski, R. A. & Goto, H., 2007, In : Veterinary Anaesthesia and Analgesia. 34, 3, p. 149 - 156 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Examination of the role of intestinal fatty acid-binding protein in drug absorption using a parallel artificial membrane permeability assay

Velkov, T., Horne, H. J., Laguerre, A. K., Jones, E. D., Scanlon, M. & Porter, C. J., 2007, In : Chemistry and Biology. 14, 4, p. 453 - 465 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification and quantification of antioxidants in Fructus Lycii

Le, K., Chiu, F. C. K. & Ng, K. F., 2007, In : Food Chemistry. 105, 1, p. 353 - 363 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Impact of surface derivatization of poly-L-lysine dendrimers with anionic arylsulfonate or succinate groups on intravenous pharmacokinetics and disposition

Kaminskas, L. M., Boyd, B. J., Karellas, P., Henderson, S., Giannis, M., Krippner, G. Y. & Porter, C. J., 2007, In : Molecular Pharmaceutics. 4, 6, p. 949 - 961 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Iron-mediated degradation kinetics of substituted dispiro-1,2,4-trioxolane antimalarials

Creek, D. J., Charman, W. N., Chiu, F. C. K., Prankerd, R. J., McCullough, K. J., Dong, Y., Vennerstrom, J. & Charman, S. A., 2007, In : Journal of Pharmaceutical Sciences. 96, 11, p. 2945 - 2956 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Laser diffraction particle sizing of cohesive lactose powders

Adi, H., Larson, I. C. & Stewart, P. J., 2007, In : Powder Technology. 179, 1-2, p. 90 - 94 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs

Porter, C. J., Trevaskis, N. & Charman, W. N., 2007, In : Nature Reviews Drug Discovery. 6, 14, p. 231 - 248 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Low dose lipid formulations: effects on gastric emptying and biliary secretion

Kossena, G. A., Charman, W. N., Wilson, C., O'Mahony, B., Lindsay, B., Hempenstall, J., Davidson, C., Crowley, P. & Porter, C. J., 2007, In : Pharmaceutical Research. 24, 11, p. 2084 - 2096 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Lymphatic absorption of subcutaneously administered proteins: influence of different injection sites on the absorption of darbepoetin alfa using a sheep model

Kota, J., Machavaram, K. K., McLennan, D. N., Edwards, G. A., Porter, C. J. & Charman, S. A., 2007, In : Drug Metabolism and Disposition. 35, 12, p. 2211 - 2217 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Probing the Flexibility of the DsbA Oxidoreductase from Vibrio cholerae-a 15N - 1H Heteronuclear NMR Relaxation Analysis of Oxidized and Reduced Forms of DsbA

Horne, H. J., d'Auvergne, E. J., Coles, M., Velkov, T., Chin, Y., Charman, W. N., Prankerd, R. J., Gooley, P. & Scanlon, M., 2007, In : Journal of Molecular Biology. 371, 3, p. 703 - 716 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Self-assembled geometric liquid-crystalline nanoparticles imaged in three dimensions: hexosomes are not necessarily flat hexagonal prisms

Boyd, B. J., Rizwan, S., Dong, Y-D., Hook, S. M. & Rades, T., 2007, In : Langmuir: the ACS journal of surfaces and colloids. 23, 25, p. 12461 - 12464 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Single quadrupole mass spectrometry for pre-clinical pharmacokinetic analysis: Quantitation of carvedilol in dog plasma

McIntosh, M. P., Carlson, B. J., Schorno, K. S. & Rajewski, R. A., 2007, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 852, p. 665 - 668 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Spiro- and dispiro-1,2-dioxolanes: contribution of iron(II)-mediated one-electron vs two-electron reduction to the activity of antimalarial peroxides

Wang, X., Dong, Y., Wittlin, S., Creek, D., Chollet, J., Charman, S. A., Santo Tomas, J., Scheurer, C., Snyder, C. & Vennerstrom, J., 2007, In : Journal of Medicinal Chemistry. 50, 23, p. 5840 - 5847 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Use of milling and wet sieving to produce narrow particle size distributions of lactose monohydrate in the sub-sieve range

Adi, H., Larson, I. C. & Stewart, P. J., 2007, In : Powder Technology. 179, 1-2, p. 95 - 99 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides

Tang, Y., Dong, Y., Wittlin, S., Charman, S. A., Chollet, J., Chiu, F. C. K., Charman, W. N., Matile, H., Urwyler, H., Dorn, A., Bajpai, S., Wang, X., Padmanilayam, M., Karle, J. M., Brun, R. & Vennerstrom, J., 2007, In : Bioorganic and Medicinal Chemistry Letters. 17, 5, p. 1260 - 1265 6 p.

Research output: Contribution to journalArticleResearchpeer-review

A protocol for the combined sub-fractionation and delipidation of lipid binding proteins using hydrophobic interaction chromatography

Velkov, T., Lim, M. L. R., Capuano, B. & Prankerd, R. J., 2008, In : Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 867, 2, p. 238 - 246 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of the drug binding specificity of rat liver fatty acid binding protein

Chuang, S., Velkov, T., Horne, J., Porter, C. J. & Scanlon, M., 2008, In : Journal of Medicinal Chemistry. 51, 13, p. 3755 - 3764 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of the two major CYP450 metabolites of ozonide (1,2,4-trioxolane) OZ277

Zhou, L., Alker, A., Ruf, A., Wang, X., Chiu, F. C. K., Morizzi, J., Charman, S. A., Charman, W. N., Scheurer, C., Wittlin, S., Dong, Y., Hunziker, D. & Vennerstrom, J., 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 5, p. 1555 - 1558 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Cospray dried antibiotics for dry powder lung delivery

Adi, H., Young, P. M., Chan, H-K., Stewart, P. J., Agus, H. & Traini, D., 2008, In : Journal of Pharmaceutical Sciences. 97, p. 3356 - 3366 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhancing intestinal drug solubilisation using lipid-based delivery systems

Porter, C. J., Pouton, C. W., Cuine, J. & Charman, W. N., 2008, In : Advanced Drug Delivery Reviews. 60, 6, p. 673 - 691 19 p.

Research output: Contribution to journalArticleResearchpeer-review