Research Output 1975 2019

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2004

Modeling the deagglomeration of micronised benzodiazepines from powder mixtures added to dissolution media

Zhao, F-Y. & Stewart, P. J., 2004, In : Journal of Pharmaceutical Sciences. 93, 6, p. 1618 - 1627 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Modification of buccal drug delivery following pretreatment with skin penetration enhancers

Nicolazzo, J. A., Reed, B. L. & Finnin, B. C., 2004, In : Journal of Pharmaceutical Sciences. 93, 8, p. 2054 - 2063 10 p.

Research output: Contribution to journalArticleResearchpeer-review

New manzamine alkaloids from an Indo-Pacific sponge. Pharmacokinetics, oral availability, and the significant activity of several manzamines against HIV-I, AIDS opportunistic infections, and inflammatory diseases

Yousaf, M., Hammond, N. L., Peng, J., Wahyuono, S., McIntosh, K. A., Charman, W. N., Mayer, A. M. S. & Hamann, M. T., 2004, In : Journal of Medicinal Chemistry. 47, 14, p. 3512 - 3517 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Orally active antimalarials: hydrolytically stable derivatives of 10-trifluoromethyl anhydrodihydroartemisinin

Grellepois, F., Chorki, F., Ourevitch, M., Charneau, S., Grellier, P., McIntosh, K. A., Charman, W. N., Pradines, B., Crousse, B., Bonnet-Delpon, D. & Begue, J-P., 2004, In : Journal of Medicinal Chemistry. 47, 6, p. 1423 - 1433 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetics of recombinant human leukemia inhibitory factor in sheep

Segrave, A. M., Mager, D. E., Charman, S. A., Edwards, G. & Porter, C. J. H., Jun 2004, In : Journal of Pharmacology and Experimental Therapeutics. 309, 3, p. 1085-1092 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Probing drug solubilization patterns in the gastrointestinal tract after administration of lipid-based delivery systems: a phase diagram approach

Kossena, G. A., Charman, W. N., Boyd, B. J., Dunstan, D. E. & Porter, C. J. H., 2004, In : Journal of Pharmaceutical Sciences. 93, 2, p. 332 - 348 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Simple method for the assay of linezolid in Brain Heart Infusion broth by high-performance liquid chromatography

Li, J., Rayner, C. R., Dixson, S. D. & Nation, R. L., 2004, In : Biomedical Chromatography. 18, 1, p. 1 - 5 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Susceptibility to lipase-mediated digestion reduces the oral bioavailability of danazol after administration as a medium-chain lipid-based microemulsion formulation

Porter, C. J. H., Kaukonen, A. M., Boyd, B. J., Edwards, G. A. & Charman, W. N., 2004, In : Pharmaceutical Research. 21, 8, p. 1405 - 1412 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The cohesive-adhesive balances in dry powder inhaler formulations I: Direct quantification by atomic force microscopy

Begat, P., Morton, D. A. V., Staniforth, J. N. & Price, R., 2004, In : Pharmaceutical Research. 21, 9, p. 1591 - 1597 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The Cohesive-Adhesive Balances in Dry Powder Inhaler Formulations II: Influence on Fine Particle Delivery Characteristics

Begat, P., Morton, D. A. V., Staniforth, J. N. & Price, R., 2004, In : Pharmaceutical Research. 21, 10, p. 1826 - 1833 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The interaction of the penetration enhancer DDAIP with a phospholipid model membrane

Wolka, A. M., Rytting, J. H., Reed, B. L. & Finnin, B. C., 2004, In : International Journal of Pharmaceutics. 271, 1-Feb, p. 5 - 10 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The transdermal revolution

Thomas, B. J. & Finnin, B. C., 2004, In : Drug Discovery Today. 9, 16, p. 697 - 703 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Use of in vitro lipid digestion data to explain the in vivo performance of triglyceride-based oral lipid formulations of poorly water-soluble drugs: studies with halofantrine

Porter, C. J. H., Kaukonen, A. M., Taillardat-Bertschinger, A., Boyd, B. J., O'Connor, J. M., Edwards, G. A. & Charman, W. N., 2004, In : Journal of Pharmaceutical Sciences. 93, 5, p. 1110 - 1121 12 p.

Research output: Contribution to journalArticleResearchpeer-review

2005

An improved method for the purification of rat liver-type fatty acid binding protein from Escherichia coli

Velkov, T., Chuang, S., Prankerd, R. J., Sakellaris, H. H., Porter, C. J. H. & Scanlon, M. J., 2005, In : Protein Expression and Purification. 44, 1, p. 23 - 31 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Atomic force microscopy and direct surface force measurements (IUPAC technical report)

Ralston, J., Larson, I. C., Rutland, M. W., Feiler, A. A. & Kleijn, M., 2005, In : Pure and Applied Chemistry. 77, 12, p. 2149 - 2170 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Bile increases intestinal lymphatic drug transport in the fasted rat

Trevaskis, N., Porter, C. J. H. & Charman, W. N., 2005, In : Pharmaceutical Research. 22, 11, p. 1863 - 1870 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Buccal Penetration Enhancers - How Do They Really Work?

Nicolazzo, J., Reed, B. L. & Finnin, B. C., 2005, In : Journal of Controlled Release. 105, 18, p. 1 - 15 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Colloidal Drug Delivery

Boyd, B. J., 2005, In : Drug Delivery Report Autumn/Winter 2005. 15, p. 63 - 70 8 p.

Research output: Contribution to journalArticleOther

Enhanced buccal mucosal retention and reduced buccal permeabiltiy of estradiol in the presence of padimate O and Azone(R): A mechanistic study

Nicolazzo, J., Reed, B. L. & Finnin, B. C., 2005, In : Journal of Pharmaceutical Sciences. 94, 4, p. 873 - 882 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhancing the buccal mucosal uptake and retention of triamcinolone acetonide

Nicolazzo, J. A., Reed, B. L. & Finnin, B. C., 2005, In : Journal of Controlled Release. 105, 3, p. 240 - 248 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Factors affecting shear thickening behavior of a concentrated injectable suspension of levodopa

Allahham, A., Stewart, P. J., Marriott, J. L. & Mainwaring, D. E., 2005, In : Journal of Pharmaceutical Sciences. 94, 11, p. 2393 - 2402 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Formulation of poorly water-soluble drugs for oral administration

Pouton, C. W., 2005, In : Bull. Tech. Gattefosse. 98, p. 39-51 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Human bioavailability of propranolol from a matrix-in-cylinder system with a HPMC-Gelucire(R) core

Mehuys, E., Remon, J. P., Korst, A., Van Bortel, L., Mols, R., Augustijns, P., Porter, C. J. H. & Vervaet, C., 2005, In : Journal of Controlled Release. 107, p. 523 - 536 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of the intermediate digestion phases of common formulation lipids on the absorption of a poorly water-soluble drug

Kossena, G. A., Charman, W. N., Boyd, B. J. & Porter, C. J. H., 2005, In : Journal of Pharmaceutical Sciences. 94, 3, p. 481 - 492 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Inter- and intralaboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasi-standardized methods and materials

Chilcott, R. P., Barai, N., Beezer, A. E., Brain, S. I., Brown, M. B., Bunge, A. L., Burgess, S. E., Cross, S., Dalton, C. H., Dias, M., Farinha, A., Finnin, B. C., Gallgher, S. J., Green, D. M., Gunt, H., Gwyther, R. L., Heard, C. M., Jarvis, C. A., Kamiyama, F., Kasting, G. B. & 22 othersLey, E. E., Lim, S. T., Mcnaughton, G. S., Morris, A., Nazemi, M. H., Pellet, M. A., Du Plessis, J., Quan, Y. S., Raghavan, S. L., Roberts, M., Romonchuk, W., Roper, C. S., Schenk, D., Simonsen, L., Simpson, A., Traversa, B. D., Trottet, L., Watkinson, A., Wilkinson, S. C., Williams, F. M., Yamamoto, A. & Hadgraft, J., 2005, In : Journal of Pharmaceutical Sciences. 94, 3, p. 632 - 638 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Kinetics of iron-mediated artemisinin degradation: effect of solvent composition and iron salt

Creek, D. J., Chiu, F. C. K., Prankerd, R. J., Charman, S. A. & Charman, W. N., 2005, In : Journal of Pharmaceutical Sciences. 94, 8, p. 1820 - 1829 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Lymphatic absorption is the primary contributor to the systemic availability of epoetin alfa following subcutaneous administration to sheep

McLennan, D. N., Porter, C. J. H., Edwards, G. A., Martin, S. W., Heatherington, A. C. & Charman, S. A., 2005, In : Journal of Pharmacology and Experimental Therapeutics. 313, 1, p. 345 - 351 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Measurement of lactose crystallinity using Raman spectroscopy

Murphy, B. M., Prescott, S. W. & Larson, I. C., 2005, In : Journal of Pharmaceutical and Biomedical Analysis. 38, 1, p. 186 - 190 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Mechanisms of action of novel skin penetration enhancers: phospholipid versus skin lipid liposomes

El Maghraby, G. M. M., Campbell, M. & Finnin, B. C., 2005, In : International Journal of Pharmaceutics. 305, 1-Feb, p. 90 - 104 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Morphology and gelation of thermosensitive chitosan hydrogels

Crompton, K. E., Prankerd, R. J., Paganin, D. M., Scott, T. F., Horne, M. K., Finkelstein, D. I., Gross, K. A. & Forsythe, J. S., 2005, In : Biophysical Chemistry. 117, 1, p. 47 - 53 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes

Dong, Y., Chollet, J., Matile, H., Charman, S. A., Chiu, F. C. K., Charman, W. N., Scorneaux, B., Urwyler, H., Santo Tomas, J., Scheurer, C., Snyder, C., Dorn, A., Wang, X., Karle, J. M., Tang, Y., Wittlin, S., Brun, R. & Vennerstrom, J. L., 2005, In : Journal of Medicinal Chemistry. 48, 15, p. 4953 - 4961 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Subcutaneous drug delivery and the role of the lymphatics

McLennan, D. N., Porter, C. J. H. & Charman, S. A., 2005, In : Drug Discovery Today: Technologies. 2, 1, p. 89-96 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Submicron dispersions of hexosomes based on novel glycerate surfactants

Fong, C., Krodkiewska, I., Wells, D., Boyd, B. J., Booth, J., Bhargava, S., McDowall, A. & Hartley, P. G., 2005, In : Australian Journal of Chemistry. 58, 9, p. 683 - 687 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Surface roughness contribution to the adhesion force distribution of salmeterol xinafoate on lactose carriers by atomic force microscopy

Islam, M. N., Stewart, P. J., Larson, I. C. & Hartley, P., 2005, In : Journal of Pharmaceutical Sciences. 94, 7, p. 1500 - 1511 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Synergistic enhancement of testosterone transdermal delivery

Nicolazzo, J. A., Morgan, T. M., Reed, B. L. & Finnin, B. C., 2005, In : Journal of Controlled Release. 103, 3, p. 577 - 585 9 p.

Research output: Contribution to journalArticleResearchpeer-review

The application of problem-based learning to the teaching of microbiology for pharmacy students

Jones, K. M., 2005, In : Pharmacy Education. 5, 1, p. 13 - 18 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The Influence of Force Control Agents on the Cohesive-Adhesive Balance in Dry Powder Inhaler Formulations

Begat, P., Price, R., Harris, H., Morton, D. A. V. & Staniforth, J. N., 2005, In : Kona Powder and Particle Journal. 23, p. 109 - 121 13 p.

Research output: Contribution to journalArticleResearchpeer-review

The interaction of lipophilic drugs with intestinal fatty acid-binding protein

Velkov, T., Chuang, S., Wielens, J., Sakellaris, H. H., Charman, W. N., Porter, C. J. & Scanlon, M., 2005, In : Journal of Biological Chemistry. 280, 18, p. 17769 - 17776 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Tumoral drug metabolism: overview and its implications for cancer therapy

Michael, M. & Doherty, M. M., 2005, In : Journal of Clinical Oncology. 23, 1, p. 205 - 229 25 p.

Research output: Contribution to journalArticleResearchpeer-review

2006

Agglomerate strength and dispersion of salmeterol xinafoate from powder mixtures for inhalation

Adi, H., Larson, I. C., Chiou, H., Young, P. M., Traini, D. & Stewart, P. J., 2006, In : Pharmaceutical Research. 23, 11, p. 2556 - 2565 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Alteration of the intravenous pharmacokinetics of a synthetic ozonide antimalarial in the presence of a modified cyclodextrin

Charman, S. A., Perry, C. S., Chiu, F. C. K., McIntosh, K. A., Prankerd, R. J. & Charman, W. N., 2006, In : Journal of Pharmaceutical Sciences. 95, 2, p. 256 - 267 12 p.

Research output: Contribution to journalArticleResearchpeer-review

An acute and coincident increase in FABP expression and lymphatic lipid and drug transport occurs during intestinal infusion of lipid-based drug formulations to rats

Trevaskis, N. L., Lo, C. M., Ma, L. Y., Tso, P., Irving, H. R., Porter, C. J. H. & Charman, W. N., 2006, In : Pharmaceutical Research. 23, 8, p. 1786 - 1796 11 p.

Research output: Contribution to journalArticleResearchpeer-review

An examination of the interplay between enterocyte-based metabolism and lymphatic drug transport in the rat

Trevaskis, N., Porter, C. J. H. & Charman, W. N., 2006, In : Drug Metabolism and Disposition. 34, 5, p. 729 - 733 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine

Padmanilayam, M., Scorneaux, B., Dong, Y., Chollet, J., Matile, H., Charman, S. A., Creek, D. J., Charman, W. N., Santo Tomas, J., Scheurer, C., Wittlin, S., Brun, R. & Vennerstrom, J., 2006, In : Bioorganic and Medicinal Chemistry Letters. 16, 21, p. 5542 - 5545 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Antioxidant activity of hot water extract from the fruit of the Doum palm, Hyphaene thebaica

Hsu, B., Coupar, I. M. & Ng, K., 2006, In : Food Chemistry. 98, 2, p. 317 - 328 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Bulk and dispersed aqueous phase behavior of phytantriol: effect of vitamin E acetate and F127 polymer on liquid crystal nanostructure

Dong, Y-D., Larson, I. C., Hanley, T. L. & Boyd, B. J., 2006, In : Langmuir: the ACS journal of surfaces and colloids. 22, 23, p. 9512 - 9518 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Cationic poly-L-lysine dendrimers: Pharmacokinetics, biodistribution, and evidence for metabolism and bioresorption after intravenous administration to rats

Boyd, B. J., Kaminskas, L. M., Karellas, P., Krippner, G. Y., Lessene, R. & Porter, C. J. H., 2006, In : Molecular Pharmaceutics. 3, 5, p. 614 - 627 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Chemical kinetics and aqueous degradation pathways of a new class of synthetic ozonide antimalarials

Perry, C. S., Charman, S. A., Prankerd, R. J., Chiu, F. C. K., Dong, Y., Vennerstrom, J. L. & Charman, W. N., 2006, In : Journal of Pharmaceutical Sciences. 95, 4, p. 737 - 747 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of functional group polarity on the antimalarial activity of spiro and dispiro-1,2,4-trioxolanes

Dong, Y., Tang, Y., Chollet, J., Matile, H., Wittlin, S., Charman, S. A., Charman, W. N., Santo Tomas, J., Scheurer, C., Snyder, C., Scorneaux, B., Bajpai, S., Alexander, S. A., Wang, X., Padmanilayam, M., Cheruku, S. R., Brun, R. & Vennerstrom, J. L., 2006, In : Bioorganic & Medicinal Chemistry. 14, 18, p. 6368 - 6382 15 p.

Research output: Contribution to journalArticleResearchpeer-review