Research Output 1975 2019

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2001

The impact of P-glycoprotein efflux on enterocyte residence time and enterocyte-based metabolism of verapamil

Johnson, B. M., Charman, W. N. & Porter, C. J. H., 2001, In : Journal of Pharmacy and Pharmacology. 53, 12, p. 1611 - 1619 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Use of discrete element method simulation in studying fluidization characteristics: influence of interparticle force

Rhodes, M. J., Wang, S. S., Nguyen, M., Stewart, P. J. & Liffman, K., 2001, In : Chemical Engineering Science. 56, 1, p. 69 - 76 8 p.

Research output: Contribution to journalArticleResearchpeer-review

A physicochemical basis for the extensive intestinal lymphatic transport of a poorly lipid soluble antimalarial, halofantrine hydrochloride, after postprandial administration to dogs

Khoo, S. M., Prankerd, R. J., Edwards, G. A., Porter, C. J. H. & Charman, W. N., 2002, In : Journal of Pharmaceutical Sciences. 91, 3, p. 647 - 659 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Crushing or altering medications: What's happen residential aged -care faciiities?

Paradiso, L. M., Roughead, E. E., Gilbert, A. L., Cosh, D., Nation, R. L., Barnes, L., Cheek, J. & Batlaniyne, A., 1 Sep 2002, In : Australasian Journal on Ageing. 21, 3, p. 123-127 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of dietary fatty acids on the intestinal permeability of marker drug compounds in excised rat jejunum

Vine, D. F., Charman, S. A., Gibson, P. R., Sinclair, A. J. & Porter, C. J. H., 2002, In : Journal of Pharmacy and Pharmacology. 54, 6, p. 809 - 819 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Evaluation of the in-vitro digestion profiles of long and medium chain glycerides and the phase behaviour of their lipolytic products

Sek, L., Porter, C. J. H., Kaukonen, A. M. & Charman, W. N., 2002, In : Journal of Pharmacy and Pharmacology. 54, 1, p. 29 - 41 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Kupffer cell phagocytosis and malaria. Hepatic kupffer cell phagocytic function in rats with erythrocytic-stage malaria

Nobes, M. S., Ghabrial, H., Simms, K. M., Smallwood, R. A., Morgan, D. J. & Sewell, R. B., 2002, In : Journal of Gastroenterology and Hepatology. 17, 5, p. 598 - 605 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Lipophilicity and other parameters affecting brain penetration

Atkinson, F., Cole, S., Laverty, C. E. & van de Waterbeemd, H., 2002, In : Current Medicinal Chemistry - Central Nervous System Agents. 2, 12, p. 229 - 240 12 p.

Research output: Contribution to journalArticleOther

Particle interactions involved in aerosol dispersion of ternary interactive mixtures

Louey, M. & Stewart, P. J., 2002, In : Pharmaceutical Research. 19, 10, p. 1524 - 1531 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Structure-activity relationships of the antimalarial agent artemisinin. 7. Direct modification of (+)-artemisinin and in vivo antimalarial screening of new, potential preclinical antimalarial candidates

Avery, M. A., Alvim-Gaston, M., Vroman, J. A., Wu, B., Ager, A., Peters, W., Robinson, B. L. & Charman, W. N., 2002, In : Journal of Medicinal Chemistry. 45, 19, p. 4321 - 4335 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Structured triglyceride vehicles for oral delivery of halofantrine: examination of intestinal lymphatic transport and bioavailability in conscious rats

Holm, R., Porter, C. J. H., Mullertz, A., Kristensen, H. G. & Charman, W. N., 2002, In : Pharmaceutical Research. 19, 9, p. 1354 - 1361 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The influence of aggregate microenvironment on the dissolution of oxazepam in ternary surfactant interactive mixtures

Stewart, P. J. & Liu, J., 2002, In : Journal of Pharmacy and Pharmacology. 54, 9, p. 1181 - 1187 7 p.

Research output: Contribution to journalArticleResearchpeer-review

2003

A kinetic evaluation of the absorption, efflux, and metabolism of verapamil in the autoperfused rat jejunum

Johnson, B. M., Chen, W., Borchardt, R. T., Charman, W. N. & Porter, C. J. H., 2003, In : Journal of Pharmacology and Experimental Therapeutics. 305, 1, p. 151 - 158 8 p.

Research output: Contribution to journalArticleResearchpeer-review

An electron momentum spectroscopy and density functional theory study of the outer valence electronic structure of stella-2, 6-dione

Nixon, KL., Wang, F., Campbell, L., Maddern, T., Winkler, D., Gleiter, R., Loeb, P., Weigold, E. & Brunger, M. J., 2003, In : Journal of Physics B: Atomic, Molecular and Optical Physics. 36, 14, p. 3155-3171 17 p.

Research output: Contribution to journalArticleResearchpeer-review

A novel method for determining hepatic sinusoidal oxygen permeability in the isolated perfused rat liver using [15O]O2

Froomes, P. R. A., Sachinidis, J., Ghabrial, H., Tochon-Danguy, H., Scott, A. M., Ching, M. S., Morgan, D. J. & Angus, P. W., 2003, In : Nuclear Medicine and Biology. 30, p. 93 - 100 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Characterisation of drug release from cubosomes using the pressure ultrafiltration method

Boyd, B. J., 2003, In : International Journal of Pharmaceutics. 260, 2, p. 239 - 247 9 p.

Research output: Contribution to journalArticleResearchpeer-review

De-agglomeration of micronized benzodiazepines in dissolution media measured by laser diffraction particle sizing

Zhao, F-Y. & Stewart, P. J., 2003, In : Journal of Pharmacy and Pharmacology. 55, 6, p. 749 - 755 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Desbutylhalofantrine: evaluation of QT prolongation and other cardiovascular effects after intravenous administration in vivo

McIntosh, M. P., Batey, A. J., Porter, C. J. H., Charman, W. N. & Coker, S. J., 2003, In : Journal of Cardiovascular Pharmacology. 41, 3, p. 406 - 413 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Exploring the electronic structure of 2, 6-stelladione from momentum space I: the p-dominant molecular orbitals in the outer valence shell

Wang, F., Brunger, M. J., McCarthy, I. E. & Winkler, D. A., 2003, In : Chemical Physics Letters. 382, 3, p. 217-225 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of the physico-chemical carrier properties on the in vitro aerosol deposition from interactive mixtures

Louey, M. D., Razia, S. & Stewart, P. J., 2003, In : International Journal of Pharmaceutics. 252, p. 87 - 98 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Intestinal lymphatic transport of halofantrine occurs after oral administration of a unit-dose lipid-based formulation to fasted dogs

Khoo, S-M., Shackleford, D. M., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 2003, In : Pharmaceutical Research. 20, 9, p. 1460 - 1465 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Investigating the patient who has hepatitis B

Wong, M-L. & Gibson, P. R., 2003, In : Medicine Today. 4, 5, p. 72 - 82 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Partitioning of halofantrine hydrochloride between water, micellar solutions, and soybean oil: effects on its apparent ionization constant

Taillardat-Bertschinger, A., Perry, C. S., Galland, A., Prankerd, R. J. & Charman, W. N., 2003, In : Journal of Pharmaceutical Sciences. 92, 11, p. 2217 - 2228 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetic model to describe the lymphatic absorption of r-metHu-Leptin after subcutaneous injection to sheep

McLennan, D. N., Porter, C. J. H., Edwards, G. A., Brumm, M., Martin, S. W. & Charman, S. A., 1 Aug 2003, In : Pharmaceutical Research. 20, 8, p. 1156-1162 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Self-micellization of gemfibrozil 1-0- acyl glucuronide in aqueous solution

Shackleford, D. M., Prankerd, R. J., Scanlon, M. J. & Charman, W. N., 2003, In : Pharmaceutical Research. 20, 3, p. 465 - 470 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The effects of phytoestrogenic isoflavones on the formation and disposition of paracetamol sulfate in the isolated perfused rat liver

Lucas, A. N., Nation, R. L., Milne, R. W., Reynolds, G. D. & Evans, A. M., 1 May 2003, In : Journal of Pharmacy and Pharmacology. 55, 5, p. 639-646 8 p.

Research output: Contribution to journalArticleResearchpeer-review

The effects of the phytoestrogenic isoflavone genistein on the hepatic disposition of preformed and hepatically generated gemfibrozil 1-0-acyl glucuronide in the isolated perfused rat liver

Lucas, A. N., Brogan, L. R., Nation, R. L., Milne, R. W., Evans, A. M. & Shackleford, D. M., 2003, In : Journal of Pharmacy and Pharmacology. 55, p. 1433 - 1439 7 p.

Research output: Contribution to journalArticleResearchpeer-review

The effects of various in vitro conditions on the permeability characteristics of the buccal mucosa

Nicolazzo, J., Reed, B. L. & Finnin, B. C., 2003, In : Journal of Pharmaceutical Sciences. 92, 12, p. 2399 - 2410 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Tumoral drug metabolism: perspectives and therapeutic implications

Doherty, M. M. & Michael, M., 2003, In : Current Drug Metabolism. 4, 2, p. 131 - 149 19 p.

Research output: Contribution to journalArticleResearchpeer-review

2004

Active and intelligent inhaler device development

Tobyn, M., Staniforth, J. N., Morton, D. A. V., Harmer, Q. & Newton, M. E., 2004, In : International Journal of Pharmaceutics. 277, 1-2, p. 31 - 37 7 p.

Research output: Contribution to journalArticleResearchpeer-review

A novel cubic phase of medium chain lipid origin for the delivery of poorly water soluble drugs

Kossena, G. A., Charman, W. N., Boyd, B. J. & Porter, C. J. H., 2004, In : Journal of Controlled Release. 99, 2, p. 217 - 229 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Assessment of the effects of sodium dodecyl sulfate on the buccal permeability of caffeine and estradiol

Nicolazzo, J. A., Reed, B. L. & Finnin, B. C., 2004, In : Journal of Pharmaceutical Sciences. 93, 2, p. 431 - 440 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Degradation of berenil (diminazene aceturate) in acidic aqueous solution

Campbell, M., Prankerd, R. J., Davie, A. S. & Charman, W. N., 2004, In : Journal of Pharmacy and Pharmacology. 56, 10, p. 1327 - 1332 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Development and application of a micro-capillary rheometer for in-vitro evaluation of parenteral injectability

Allahham, A., Mainwaring, D. E., Stewart, P. J. & Marriott, J. L., 2004, In : Journal of Pharmacy and Pharmacology. 56, 6, p. 709 - 716 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Drug solubilization behavior during in vitro digestion of simple triglyceride lipid solution formulations

Kaukonen, A. M., Boyd, B. J., Porter, C. J. H. & Charman, W. N., 2004, In : Pharmaceutical Research. 21, 2, p. 245 - 253 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Drug solubilization behaviour during in vitro digestion of suspension formulations of poorly water-soluble drugs in triglyceride lipids

Kaukonen, A. M., Boyd, B. J., Charman, W. N. & Porter, C. J. H., 2004, In : Pharmaceutical Research. 21, 2, p. 254 - 260 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of carrier size on the dispersion of salmeterol xinafoate from interactive mixtures

Islam, M. N., Stewart, P. J., Larson, I. C. & Hartley, P., 2004, In : Journal of Pharmaceutical Sciences. 93, 4, p. 1030 - 1038 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Flow and injection characteristics of pharmaceutical parenteral formulations using a micro-capillary rheometer

Allahham, A., Stewart, P. J., Marriott, J. L. & Mainwaring, D. E., 2004, In : International Journal of Pharmaceutics. 270, 1-2, p. 139 - 148 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Identification of an antimalarial synthetic trioxolane drug development candidate

Vennerstrom, J. L., Arbe-Barnes, S., Brun, R., Charman, S. A., Chiu, F. C. K., Chollet, J., Dong, Y., Dorn, A., Hunziker, D., Matile, H., McIntosh, K. A., Padmanilayam, M., Santo Tomas, J., Scheurer, C., Scorneaux, B., Tang, Y., Urwyler, H., Wittlin, S. & Charman, W. N., 19 Aug 2004, In : Nature. 430, 7002, p. 900-904 5 p.

Research output: Contribution to journalArticleResearchpeer-review

In vitro and in vivo evaluation of a sulfobutyl ether beta-cyclodextrin enabled etomidate formulation

McIntosh, M. P., Schwarting, N. & Rajewski, R. A., 2004, In : Journal of Pharmaceutical Sciences. 93, 10, p. 2585 - 2594 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Lactose surface modification by decantation: are drug-fine lactose ratios the key to better dispersion of slametereol xinafoate from lactose-intercative mixtures?

Islam, M. N., Stewart, P. J., Larson, I. C. & Hartley, P., 2004, In : Pharmaceutical Research. 21, 3, p. 492 - 499 8 p.

Research output: Contribution to journalArticleResearchpeer-review