Research Output 1975 2019

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1997

Effects of acute myocardial infarction on theophylline elimination in rats

Ng, C. Y., Ghabrial, H., Morgan, D. J., Smallwood, R. A. & Angus, P. W., 1997, In : Drug Metabolism and Disposition. p. 61 - 65 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of albumin on the disposition of morphine and morphine-3-glucuronidine in the rat isolated perfused liver

O'Brien, J. A., Evans, A. M. & Nation, R. L., 1 Jan 1997, In : Clinical and Experimental Pharmacology and Physiology. 24, 2, p. 143-148 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Formulation of self-emulsifying drug delivery systems: Advanced Drug Delivery Reviews

Pouton, C. W., 1997, In : Advanced Drug Delivery Reviews. 25, p. 47-58 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of lipolysis on drug absorption from the gastro-intestinal tract: Advanced Drug Delivery Reviews

MacGregor, K. J., Embleton, J. K., Lacy, J. E., Perry, E. A., Solomon, L. J., Seager, H. & Pouton, C. W., 1997, In : Advanced Drug Delivery Reviews. 25, p. 33-46 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Influence of renal failure on the disposition of morphine, morphine-3- glucuronide and morphine-6-glucuronide in sheep during intravenous infusion with morphine

Milne, R. W., McLean, C. F., Mather, L. E., Nation, R. L., Runciman, W. B., Rutten, A. J. & Somogyi, A. A., 1 Aug 1997, In : Journal of Pharmacology and Experimental Therapeutics. 282, 2, p. 779-786 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Optimization of the MTT assay for B16 murine melanoma cells and its application in assessing growth inhibition by polyamines and novel polyamine conjugates

Qarawi, M. A., Carrington, S., Blagbrough, I. S., Moss, S. H. & Pouton, C. W., 1 Dec 1997, In : Pharmaceutical Sciences. 3, 5-6, p. 235-239 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Pharmacokinetics and pharmacodynamics of MX2 hydrochloride in patients with advanced malignant disease

Morgan, D. J., Hill, J. S., Clarke, K., Stylli, S. S., Park, S. J., Cebon, J., Basser, R. L., Kaye, A. H., Geldard, H., Maher, D. W. & Green, M. D., 1997, In : Cancer Chemotherapy and Pharmacology. p. 202 - 208 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Physicochemical and physiological mechanisms for the effects of food on drug absorption: The role of lipids and pH

Charman, W. N., Porter, C. J. H., Mithani, S. & Dressman, J. B., 1997, In : Journal of Pharmaceutical Sciences. p. 269 - 282 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Polyamino acid/DNA complexes for gene therapy: Particle characterisation and biological activity

Thomas, B. J., Lucas, P., Moss, S. H. & Pouton, C. W., 1 Jan 1997, In : Proceedings of the Controlled Release Society. 24, p. 643-644 2 p.

Research output: Contribution to journalArticleResearchpeer-review

The effect of old age on the disposition and antinociceptive response of morphine and morphine-6β-glucuronide in the rat

Van Crugten, J. T., Somogyi, A. A., Nation, R. L. & Reynolds, G., 1 Jun 1997, In : Pain. 71, 2, p. 199-205 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Uptake of drugs into the intestinal lymphatics after oral administration

Porter, C. J. H. & Charman, W. N., 1997, In : Advanced Drug Delivery Reviews. p. 71 - 89 19 p.

Research output: Contribution to journalArticleResearchpeer-review

1998

Analytical methods and stability assessment of liquid yeast derived sucrase

McIntosh, K. A., Charman, S. A., Borgen, L. A. & Charman, W. N., 1998, In : Journal of Pharmaceutical and Biomedical Analysis. p. 1037 - 1045 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A priming dose of propranolol reduces the availability of a subsequent dose in the isolated perfused rat liver preparation

Ghabrial, H., Sewell, R. B., Smallwood, R. A. & Morgan, D. J., 1998, In : Clinical and Experimental Pharmacology and Physiology. p. 110 - 113 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Association of halofantrine with postprandially derived plasma lipoproteins decreases its clearance relative to administration in the fasted state

Humberstone, A. J., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 1998, In : Journal of Pharmaceutical Sciences. p. 936 - 942 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Asthma medications, equipment supplied and sources of information for Australian community pharmacists

Gattera, J. A., Abramson, M. J. & Roller, L., 1998, In : The Australian Journal of Pharmacy. p. 840 - 848 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Compatibility of ketamine and morphine injections

Lau, M-H., Hackman, C. & Morgan, D. J., 1998, In : Pain. 75, p. 389 - 390 2 p.

Research output: Contribution to journalArticleOther

Computer-based course for foreign pharmacists seeking registration in Australia

Pappas, A., Stewart, K., Roller, L., Reed, B. L., Cesnik, B., Hoffman, J. & Sorgetti, L., 1998, In : Pharmaceutical Journal. p. 586 - 587 2 p.

Research output: Contribution to journalArticleOther

Computer-based courses for foreign pharmacists seeking registration in Australia

Pappas, A., Stewart, K., Roller, L., Reed, B. L., Cesnik, B., Hoffman, J. & Sorgetti, L., 1998, In : Pharmaceutical Journal. p. 586 - 587 2 p.

Research output: Contribution to journalArticleOther

Deaggregation during the dissolution of benzodiazepines in interactive mixtures

Liu, J. & Stewart, P. J., 1998, In : Journal of Pharmaceutical Sciences. p. 1632 - 1638 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Degradation of recombinant porcine growth hormone in the presence of guanidine hydrochloride

McCrossin, L. E., Charman, W. N. & Charman, S. A., 30 Oct 1998, In : International Journal of Pharmaceutics. 173, 1-2, p. 157-170 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Drug-induced liver disease

Morgan, D. J., 1998, In : Current Practice in Medicine. p. 68 - 70 3 p.

Research output: Contribution to journalArticleOther

Effect of alterd serum lipid concentrations on the IC50 of Halofantrine against Plasmodium Falciparum

Humberstone, A. J., Cowman, A. F., Horton, J. & Charman, W. N., 1998, In : Journal of Pharmaceutical Sciences. p. 256 - 258 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of altered serum lipid concentrations on the IC50 of halofantrine against Plasmodium Falciparum

Humberstone, A. J., Cowman, A. F., Horton, J. & Charman, W. N., 1 Jan 1998, In : Journal of Pharmaceutical Sciences. 87, 2, p. 256-258 3 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of cationic drugs on the renal secretion of ranitidine in the rat isolated perfused kidney

Nation, R. L., Evans, A. M., Cabot, J. L., Shanahan, K. M. & Hsyu, P. H., 1 Jan 1998, In : Clinical and Experimental Pharmacology and Physiology. 25, 1, p. 33-37 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of filgrastim on the pharmacokinetics of MX2 hydrochloride in patients with advanced malignant disease

Morgan, D. J., Hill, J. S., Clarke, K., Stylli, S. S., Park, S. J., Cebon, J., Basser, R. L., Kaye, A. H., Geldard, H., Maher, D. W. & Green, M. D., 1998, In : Cancer Chemotherapy and Pharmacology. p. 423 - 426 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhanced skin permeation of sex hormones with novel topical spray vehicles

Morgan, T. M., Reed, B. L. & Finnin, B. C., 1998, In : Journal of Pharmaceutical Sciences. p. 1213 - 1218 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Enhanced transdermal delivery of sex hormones in swine with a novel topical aerosol

Morgan, T. M., Parr, R. A., Reed, B. L. & Finnin, B. C., 1998, In : Journal of Pharmaceutical Sciences. p. 1219 - 1225 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Evaluation of a computer-based bridging course by overseas-qualified pharmacists seeking Australian registration

Pappas, A., Stewart, K., Cesnik, B., Reed, B. L., Roller, L., Hoffman, J. & Sorgetti, L., 1998, In : American Journal of Pharmaceutical Education. p. 315 - 323 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Formulation design and bioavailability assessment of lipidic self-emulsifying formulations of halofantrine

Khoo, S-M., Humberstone, A. J., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 1998, In : International Journal of Pharmaceutics. p. 155 - 164 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Glucuronidation of dihydrocodeine by human liver microsomes and the effect of inhibitors

Kirkwood, L. C., Nation, R. L. & Somogyi, A. A., 1 Jan 1998, In : Clinical and Experimental Pharmacology and Physiology. 25, 3-4, p. 266-270 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Key issues in non-viral gene delivery: Adv Drug Deliv Rev

Pouton, C. W. & Seymour, L. W., 1998, In : Advanced Drug Delivery Reviews. 34, p. 3-19 17 p.

Research output: Contribution to journalArticleResearchpeer-review

Knowledge of asthma symptoms, preventer medications and asthma counselling practices of Australian community pharmacists

Gattera, J. A., Abramson, M. J. & Roller, L., 1998, In : The Australian Journal of Pharmacy. p. 976 - 982 7 p.

Research output: Contribution to journalArticleOther

Metabolism of halofantrine to its equipotent metabolite, desbutylhalofantrine, is decreased when orally administered with ketoconazole

Khoo, S-M., Porter, C. J. H., Edwards, G. A. & Charman, W. N., 1998, In : Journal of Pharmaceutical Sciences. p. 1538 - 1541 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Myocardial effect compartment modeling of metoprolol and sotalol: Importance of myocardial subsite drug concentration

Ritchie, R. H., Morgan, D. J. & Horowitz, J. D., 1998, In : Journal of Pharmaceutical Sciences. p. 177 - 182 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Nuclear import of polypeptides, polynucleotides and supramolecular complexes: Adv Drug Deliv Rev

Pouton, C. W., 1998, In : Advanced Drug Delivery Reviews. 34, p. 51-64 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Phase I and pharmacokinetic study of KRN8602 alone and with filgrastim in patients with advanced cancer

Clarke, K., Basser, R. L., Maher, D. W., Morgan, D. J., Cebon, J., Fox, R. M., Hill, J. S., Alt, C., Bartlett, J., Geldard, H., Kaye, A. H. & Green, M. D., 1998, In : Journal of Clinical Oncology. p. 2181 - 2187 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycation-DNA complexes for gene delivery: A comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids

Pouton, C. W., Lucas, P., Thomas, B. J., Uduehi, A. N., Milroy, D. A. & Moss, S. H., 30 Apr 1998, In : Journal of Controlled Release. 53, 1-3, p. 289-299 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Polycation-DNA complexes for gene delivery: a comparison of the biopharmaceutical properties of cationic polypeptides and cationic lipids: J Control Release

Pouton, C. W., Lucas, P., Thomas, B. J., Uduehi, A. N., Milroy, D. A. & Moss, S. H., 1998, In : Journal of Controlled Release. 53, p. 289-299 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Propranolol elimination by right and left fetal liver: Studies in the intact isolated perfused fetal sheep liver

Ring, J. A., Ghabrial, H., Ching, M. S., Shulkes, A., Smallwood, R. A. & Morgan, D. J., 1998, In : Journal of Pharmacology and Experimental Therapeutics. p. 535 - 541 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Relationships among liver and kidney volumes, lean body mass and drug clearance

Narawatne, S., Brien, J-A. E., Seeman, E., Fabiny, R., Zalcberg, J. R., Cosolo, W., Angus, P. W. & Morgan, D. J., 1998, In : British Journal of Clinical Pharmacology. p. 447 - 452 6 p.

Research output: Contribution to journalArticleResearchpeer-review

The application of capillary electrophoresis for monitoring effects of excipients on protein conformation

McIntosh, K. A., Charman, W. N. & Charman, S. A., Feb 1998, In : Journal of Pharmaceutical and Biomedical Analysis. 16, 6, p. 1097-1105 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Theme title: Transport of macromolecules and viruses - Preface: Advanced Drug Delivery Reviews

Pouton, C. & Seymour, L. W., 1998, In : Advanced Drug Delivery Reviews. 34, p. 1-2 2 p.

Research output: Contribution to journalArticleResearchpeer-review

Transdermal delivery of estradiol in postmenopausal women with a novel topical aerosol

Morgan, T. M., O'Sullivan, H. M. M., Reed, B. L. & Finnin, B. C., 1998, In : Journal of Pharmaceutical Sciences. p. 1226 - 1228 3 p.

Research output: Contribution to journalArticleResearchpeer-review

1999

A novel prodrug approach for tertiary amines.3. In vivo evaluation of two N-phosphonocoxymethyl prodrugs in rats and dogs

Krise, J. P., Charman, W. N., Charman, S. A. & Stella, V. J., 1999, In : Journal of Pharmaceutical Sciences. p. 928 - 932 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Application of a loading wash-out method for investigating the hepatocellular efflux of a hepatically-generated metabolite, morphine-3-glucuronide

Evans, A. M., O'Brien, J. & Nation, R. L., 1 Jan 1999, In : Journal of Pharmacy and Pharmacology. 51, 11, p. 1289-1297 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cationic lipid-mediated transfection of differentiated Caco-2 cells: a filter culture model of gene delivery to a polarized epithelium: Pharm Res

Uduehi, A. N., Moss, S. H., Nuttall, J. & Pouton, C. W., 1999, In : Pharmaceutical Research. 16, p. 1805-1811 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Clonidine and cardiac surgery: Haemodynamic and metabolic effects, myocardial ischaemia and recovery

Myles, P. S., Hunt, J. O., Holdgaard, H. O., McRae, R., Buckland, M. R., Moloney, J., Hall, J., Bujor, M. A., Esmore, D. S., Davis, B. B. & Morgan, D. J., 1999, In : Anaesthesia and intensive care. p. 137 - 147 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparative effects of oxygen supplementation of theophylline and acetaminophen clearance in human cirrhosis

Froomes, P. R. A., Morgan, D. J., Smallwood, R. A. & Angus, P. W., 1999, In : Gastroenterology. p. 915 - 920 6 p.

Research output: Contribution to journalArticleResearchpeer-review