Research Output 1975 2019

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2019

3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity

Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 others, Price, R. N., Marfurt, J., Charman, S. A., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Edstein, M. D., Avery, V. M. & Baell, J. B., 1 Jan 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2485-2498 14 p.

Research output: Contribution to journalArticleResearchpeer-review

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Kaminskas, L. M., Williams, C. C., Leong, N. J., Chan, L. J., Butcher, N. J., Feeney, O. M., Porter, C. J. H., Tyssen, D., Tachedjian, G. & Ascher, D. B., 1 Apr 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 218-226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A fluorogenic probe based on chelation-hydrolysis-enhancement mechanism for visualizing Zn2+ in Parkinson's disease models

Zhang, G., Zhao, Y., Peng, B., Li, Z., Xu, C., Liu, Y., Zhang, C., Voelcker, N. H., Li, L. & Huang, W., 14 Apr 2019, In : Journal of Materials Chemistry B. 7, 14, p. 2252-2260 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

Patil, R., Mohanty, B., Liu, B., Chandrashekaran, I. R., Headey, S. J., Williams, M. L., Clements, C. S., Ilyichova, O., Doak, B. C., Genissel, P., Weaver, R., Vuillard, L., Halls, M. L., Porter, C. J. H. & Scanlon, M. J., 8 Mar 2019, In : Journal of Biological Chemistry. 294, 10, p. 3720-3734 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore

Sun, Y., Kakinen, A., Zhang, C., Yang, Y., Faridi, A., Davis, T. P., Cao, W., Ke, P. C. & Ding, F., 28 Jun 2019, In : Nanoscale. 11, 24, p. 11933-11945 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., May 2019, In : Small. 15, 18, 10 p., 1805166.

Research output: Contribution to journalArticleResearchpeer-review

A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL

Suys, E. J. A., Warren, D. B., Pham, A. C., Nowell, C. J., Clulow, A. J., Benameur, H., Porter, C. J. H., Pouton, C. W. & Chalmers, D. K., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 193-204 12 p.

Research output: Contribution to journalArticleResearchpeer-review

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A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M. S., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 others, Failes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 Jan 2019, In : Oncogene. 38, 20, p. 3824-3842 19 p.

Research output: Contribution to journalArticleResearchpeer-review

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Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion

Salim, M., Fraser-Miller, S. J., Sutton, J. J., Berzinš, K., Hawley, A., Clulow, A. J., Beilles, S., Gordon, K. C. & Boyd, B. J., 2 May 2019, In : Journal of Physical Chemistry Letters. 10, 9, p. 2258-2263 6 p.

Research output: Contribution to journalArticleResearchpeer-review

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A Proof of Concept for 3D Printing of Solid Lipid-Based Formulations of Poorly Water-Soluble Drugs to Control Formulation Dispersion Kinetics

Vithani, K., Goyanes, A., Jannin, V., Basit, A. W., Gaisford, S. & Boyd, B. J., 1 Jul 2019, In : Pharmaceutical Research. 36, 7, 13 p., 102.

Research output: Contribution to journalArticleResearchpeer-review

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, V. E., Deveson Lucas, D. S., López-Causapé, C., Huang, Y., Kotsimbos, T., Bulitta, J. B., Rees, M. C., Barugahare, A., Peleg, A. Y., Nation, R. L., Oliver, A., Boyce, J. D. & Landersdorfer, C. B., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02538-18.

Research output: Contribution to journalArticleResearchpeer-review

Co-delivery of RNAi and chemokine by polyarginine nanocapsules enables the modulation of myeloid-derived suppressor cells

Ledo, A. M., Sasso, M. S., Bronte, V., Marigo, I., Boyd, B. J., Garcia-Fuentes, M. & Alonso, M. J., 10 Feb 2019, In : Journal of Controlled Release. 295, p. 60-73 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Colloidal aspects of dispersion and digestion of self-dispersing lipid-based formulations for poorly water-soluble drugs

Vithani, K., Jannin, V., Pouton, C. W. & Boyd, B. J., 2019, In : Advanced Drug Delivery Reviews. 142, p. 16-34 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

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Controlling Nanomaterial Size and Shape for Biomedical Applications via Polymerization-Induced Self-Assembly

Khor, S. Y., Quinn, J. F., Whittaker, M. R., Truong, N. P. & Davis, T. P., Jan 2019, In : Macromolecular Rapid Communications. 40, 2, 22 p., 1800438.

Research output: Contribution to journalArticleResearchpeer-review

Deposition of aminomalononitrile-based films: Kinetics, chemistry, and morphology

Toh, R. J., Evans, R., Thissen, H., Voelcker, N. H., D'ischia, M. & Ball, V., 30 Jul 2019, In : Langmuir. 35, 30, p. 9896-9903 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Deuterated phytantriol – A versatile compound for probing material distribution in liquid crystalline lipid phases using neutron scattering

Yepuri, N. R., Clulow, A. J., Prentice, R. N., Gilbert, E. P., Hawley, A., Rizwan, S. B., Boyd, B. J. & Darwish, T. A., 15 Jan 2019, In : Journal of Colloid and Interface Science. 534, p. 399-407 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Development of a Shape-Controlled H2S Delivery System Using Epoxide-Functional Nanoparticles

Yu, S. H., Esser, L., Khor, S. Y., Senyschyn, D., Veldhuis, N. A., Whittaker, M. R., Ercole, F., Davis, T. P. & Quinn, J. F., 2019, In : Journal of Polymer Science, Part A: Polymer Chemistry. 57, 18, p. 1982–1993 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential functionalisation of the internal and external surfaces of carbon-stabilised nanoporous silicon

Alba, M., Robin, M., Menzies, D., Gengenbach, T. R., Prieto-Simon, B. & Voelcker, N. H., 15 Jun 2019, In : Chemical Communications. 55, 55, p. 8001-8004 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Differentiation of Rat Mesenchymal Stem Cells toward Osteogenic Lineage on Extracellular Matrix Protein Gradients

Rasi Ghaemi, S., Delalat, B., Cavallaro, A., Mierczynska-Vasilev, A., Vasilev, K. & Voelcker, N. H., 1 Sep 2019, In : Advanced Healthcare Materials. 8, 17, 11 p., 1900595.

Research output: Contribution to journalArticleResearchpeer-review

Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes

Li, T., Nowell, C. J., Cipolla, D., Rades, T. & Boyd, B. J., 1 Apr 2019, In : Molecular Pharmaceutics. 16, 4, p. 1775-1781 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Experimental and theoretical demonstrations of ultraviolet absorption enhancement in porous nano-membrane graphene

Kasry, A., Fadlallah, M. M., Voelcker, N. H. & Maarouf, A. A., 1 Dec 2019, In : Carbon. 155, p. 65-70 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis

Bulitta, J. B., Jiao, Y., Drescher, S. K., Oliver, A., Louie, A., Moya, B., Tao, X., Wittau, M., Tsuji, B. T., Zavascki, A. P., Shin, B. S., Drusano, G. L., Sörgel, F. & Landersdorfer, C. B., 6 Feb 2019, In : Clinical Pharmacokinetics. 58, 2, p. 143-156 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles

Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., May 2019, In : Macromolecular Rapid Communications. 40, 10, 6 p., 1800911.

Research output: Contribution to journalArticleResearchpeer-review

Functional Liquid Metal Nanoparticles Produced by Liquid-Based Nebulization

Tang, S. Y., Qiao, R., Lin, Y., Li, Y., Zhao, Q., Yuan, D., Yun, G., Guo, J., Dickey, M. D., Huang, T. J., Davis, T. P., Kalantar-Zadeh, K. & Li, W., Feb 2019, In : Advanced Materials Technologies. 4, 2, 9 p., 1800420.

Research output: Contribution to journalArticleResearchpeer-review

Gold microneedles fabricated by casting of gold ink used for urea sensing

Senel, M., Dervisevic, M. & Voelcker, N. H., 15 May 2019, In : Materials Letters. 243, p. 50-53 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria

Salim, M., Khan, J., Ramirez, G., Murshed, M., Clulow, A. J., Hawley, A., Ramachandruni, H., Beilles, S. & Boyd, B. J., 1 Jan 2019, In : Molecular Pharmaceutics. 16, 4, p. 1658-1668 11 p.

Research output: Contribution to journalArticleResearchpeer-review

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Improvement in the Predicted Partitioning of Alcohol and Polyethylene Oxide Groups Between Water and Octanol (logP) in Molecular Dynamics Simulations

Warren, D. B., McPhee, E., Birru, W. A., Benameur, H., Chalmers, D. K. & Pouton, C. W., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 214-222 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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Increased Expression of Renal Drug Transporters in a Mouse Model of Familial Alzheimer's Disease

Pan, Y., Omori, K., Ali, I., Tachikawa, M., Terasaki, T., Brouwer, K. L. R. & Nicolazzo, J. A., Jul 2019, In : Journal of Pharmaceutical Sciences. 108, 7, p. 2484-2489 6 p.

Research output: Contribution to journalArticleResearchpeer-review

In Situ Characterization of Protein Corona Formation on Silica Microparticles Using Confocal Laser Scanning Microscopy Combined with Microfluidics

Weiss, A. C. G., Krüger, K., Besford, Q. A., Schlenk, M., Kempe, K., Förster, S. & Caruso, F., 2019, In : ACS Applied Materials and Interfaces. 11, 2, p. 2459-2469 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Interfacial forces at layered surfaces: substrate electrical double-layer forces acting through ultrathin polymer coatings

Wang, H., Evans, D., Voelcker, N. H., Griesser, H. J. & Meagher, L., 10 Sep 2019, In : Langmuir : the ACS journal of surfaces and colloids. 35, 36, p. 11679-11689 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Jellyfish-Based Smart Wound Dressing Devices Containing In Situ Synthesized Antibacterial Nanoparticles

Nudelman, R., Alhmoud, H., Delalat, B., Fleicher, S., Fine, E., Guliakhmedova, T., Elnathan, R., Nyska, A., Voelcker, N. H., Gozin, M. & Richter, S., 2019, In : Advanced Functional Materials. 29, 38, 11 p., 1902783.

Research output: Contribution to journalArticleResearchpeer-review

Label-Free Bacterial Toxin Detection in Water Supplies Using Porous Silicon Nanochannel Sensors

Reta, N., Michelmore, A., Saint, C. P., Prieto-Simon, B. & Voelcker, N. H., 28 Jun 2019, In : ACS Sensors. 4, 6, p. 1515-1523 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Local inflammation alters the lung disposition of a drug loaded pegylated liposome after pulmonary dosing to rats

Haque, S., Feeney, O., Meeusen, E., Boyd, B. J., McIntosh, M. P., Pouton, C. W., Whittaker, M. & Kaminskas, L. M., 10 Aug 2019, In : Journal of Controlled Release. 307, p. 32-43 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Location of Solvated Probe Molecules Within Nonionic Surfactant Micelles Using Molecular Dynamics

Warren, D. B., McPhee, E., Birru, W. A., Benameur, H., Chalmers, D. K. & Pouton, C. W., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 205-213 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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Magnetic nanoparticles enhance pore blockage-based electrochemical detection of a wound biomarker

Rajeev, G., Cowin, A. J., Voelcker, N. H. & Simon, B. P., 12 Jun 2019, In : Frontiers in Chemistry. 7, JUN, 11 p., 438.

Research output: Contribution to journalArticleResearchpeer-review

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Mapping insoluble indole metabolites in the gastrointestinal environment of a murine colorectal cancer model using desorption/ionisation on porous silicon imaging

Rudd, D., Benkendorff, K., Chahal, C., Guinan, T., Gustafsson, O. J. R., Esmaeelian, B., Krysinska, H., Pogson, L., Voelcker, N. H. & Abbott, C. A., 1 Dec 2019, In : Scientific Reports. 9, 1, 12342.

Research output: Contribution to journalArticleResearchpeer-review

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Maximizing RNA Loading for Gene Silencing Using Porous Silicon Nanoparticles

Tieu, T., Dhawan, S., Haridas, V., Butler, L. M., Thissen, H., Cifuentes-Rius, A. & Voelcker, N. H., 5 Jun 2019, In : ACS Applied Materials and Interfaces. 11, 26, p. 22993-23005 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Microfluidic preparation of drug-loaded PEGylated liposomes, and the impact of liposome size on tumour retention and penetration

Dong, Y. D., Tchung, E., Nowell, C., Kaga, S., Leong, N., Mehta, D., Kaminskas, L. M. & Boyd, B. J., 2019, In : Journal of Liposome Research. 29, 1, p. 1-9 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Milk Lipids: A Complex Nutrient Delivery System

German, J. B., Argov-Argaman, N. & Boyd, B. J., 1 Jan 2019, In : Nestle Nutrition Institute Workshop Series. 90, p. 217-225 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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Modulating Targeting of Poly(ethylene glycol) Particles to Tumor Cells Using Bispecific Antibodies

Cui, J., Ju, Y., Houston, Z. H., Glass, J. J., Fletcher, N. L., Alcantara, S., Dai, Q., Howard, C. B., Mahler, S. M., Wheatley, A. K., De Rose, R., Brannon, P. T., Paterson, B. M., Donnelly, P. S., Thurecht, K. J., Caruso, F. & Kent, S. J., 9 May 2019, In : Advanced Healthcare Materials. 8, 9, 10 p., 1801607.

Research output: Contribution to journalArticleResearchpeer-review

Multiparameter toxicity screening on a chip: Effects of UV radiation and titanium dioxide nanoparticles on HaCaT cells

McCormick, S., Smith, L. E., Holmes, A. M., Tong, Z., Lombi, E., Voelcker, N. H. & Priest, C., 1 Jul 2019, In : Biomicrofluidics. 13, 4, 8 p., 044112.

Research output: Contribution to journalArticleResearchpeer-review

Open Access

Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide

Sun, Y., Kakinen, A., Xing, Y., Pilkington, E. H., Davis, T. P., Ke, P. C. & Ding, F., 1 Feb 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 2, p. 434-444 11 p.

Research output: Contribution to journalArticleResearchpeer-review

PD-L1– and calcitriol-dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease

Galea, R., Nel, H. J., Talekar, M., Liu, X., Ooi, J. D., Huynh, M., Hadjigol, S., Robson, K. J., Ting, Y. T., Cole, S., Cochlin, K., Hitchcock, S., Zeng, B., Yekollu, S., Boks, M., Goh, N., Roberts, H., Rossjohn, J., Reid, H. H., Boyd, B. J. & 7 others, Malaviya, R., Shealy, D. J., Baker, D. G., Madakamutil, L., Richard Kitching, A., O’Sullivan, B. J. & Thomas, R., 19 Sep 2019, In : JCI Insight. 4, 18, 21 p., e126025.

Research output: Contribution to journalArticleResearchpeer-review

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PEGylation and surface functionalization of liposomes containing drug nanocrystals for cell-targeted delivery

Xiao, Y., Liu, Q., Clulow, A. J., Li, T., Manohar, M., Gilbert, E. P., de Campo, L., Hawley, A. & Boyd, B. J., 1 Oct 2019, In : Colloids and Surfaces B: Biointerfaces. 182, 10 p., 110362.

Research output: Contribution to journalArticleResearchpeer-review

Photo-crosslinked coatings based on 2-hydroxypropyl acrylamide for the prevention of biofouling

Yoshikawa, C., Delalat, B., Huang, F., Braun, S., Nishijima, N., Voelcker, N. H., Kingshott, P. & Thissen, H., 16 Apr 2019, In : Journal of Materials Chemistry B. 7, 22, p. 3520-3527 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Physical and toxicological profiles of human IAPP amyloids and plaques

Kakinen, A., Sun, Y., Javed, I., Faridi, A., Pilkington, E. H., Faridi, P., Purcell, A. W., Zhou, R., Ding, F., Lin, S., Ke, P. C. & Davis, T. P., 15 Jan 2019, In : Science Bulletin. 64, 1, p. 26-35 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Pointing in the right direction: Controlling the orientation of proteins on nanoparticles improves targeting efficiency

Yong, K. W., Yuen, D., Chen, M. Z., Porter, C. J. H. & Johnston, A. P. R., 13 Mar 2019, In : Nano Letters. 19, 3, p. 1827−1831 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Polydimethylsiloxane-based giant glycosylated polymersomes with tunable bacterial affinity

Martin, L., Gurnani, P., Zhang, J., Hartlieb, M., Cameron, N. R., Eissa, A. M. & Perrier, S., 11 Mar 2019, In : Biomacromolecules. 20, 3, p. 1297-1307 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Porous Silicon Nanostructures as Effective Faradaic Electrochemical Sensing Platforms

Guo, K., Sharma, A., Toh, R. J., Alvárez de Eulate, E., Gengenbach, T. R., Cetó, X., Voelcker, N. H. & Prieto-Simón, B., 13 Jun 2019, In : Advanced Functional Materials. 29, 24, 12 p., 1809206.

Research output: Contribution to journalArticleResearchpeer-review