Research Output 1984 2019

2019

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Kaminskas, L. M., Williams, C. C., Leong, N. J., Chan, L. J., Butcher, N. J., Feeney, O. M., Porter, C. J. H., Tyssen, D., Tachedjian, G. & Ascher, D. B., 1 Apr 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 218-226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Tieu, T., Alba Martin, M., Elnathan, R., Cifuentes-Rius, A. & Voelcker, N. H., Jan 2019, In : Advanced Therapeutics. 2, 1, 25 p., 1800095.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

Patil, R., Mohanty, B., Liu, B., Chandrashekaran, I. R., Headey, S. J., Williams, M. L., Clements, C. S., Ilyichova, O., Doak, B. C., Genissel, P., Weaver, R., Vuillard, L., Halls, M. L., Porter, C. J. H. & Scanlon, M. J., 8 Mar 2019, In : Journal of Biological Chemistry. 294, 10, p. 3720-3734 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., 2019, (Accepted/In press) In : Small. 10 p., 1805166.

Research output: Contribution to journalArticleResearchpeer-review

A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL

Suys, E. J. A., Warren, D. B., Pham, A. C., Nowell, C. J., Clulow, A. J., Benameur, H., Porter, C. J. H., Pouton, C. W. & Chalmers, D. K., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 193-204 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion

Salim, M., Fraser-Miller, S. J., Sutton, J. J., Berzinš, K., Hawley, A., Clulow, A. J., Beilles, S., Gordon, K. C. & Boyd, B. J., 2 May 2019, In : Journal of Physical Chemistry Letters. 10, 9, p. 2258-2263 6 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, V. E., Deveson Lucas, D. S., López-Causapé, C., Huang, Y., Kotsimbos, T., Bulitta, J. B., Rees, M. C., Barugahare, A., Peleg, A. Y., Nation, R. L., Oliver, A., Boyce, J. D. & Landersdorfer, C. B., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02538-18.

Research output: Contribution to journalArticleResearchpeer-review

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Deuterated phytantriol – A versatile compound for probing material distribution in liquid crystalline lipid phases using neutron scattering

Yepuri, N. R., Clulow, A. J., Prentice, R. N., Gilbert, E. P., Hawley, A., Rizwan, S. B., Boyd, B. J. & Darwish, T. A., 15 Jan 2019, In : Journal of Colloid and Interface Science. 534, p. 399-407 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Editorial

Mohd Amin, M. C. I., Kiew, L. V. & Boyd, B., 15 Apr 2019, In : Drug Delivery and Translational Research. 9, 2, p. 417-417 1 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access

Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles

Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., 12 Feb 2019, (Accepted/In press) In : Macromolecular Rapid Communications. 6 p., 1800911.

Research output: Contribution to journalArticleResearchpeer-review

Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria

Salim, M., Khan, J., Ramirez, G., Murshed, M., Clulow, A. J., Hawley, A., Ramachandruni, H., Beilles, S. & Boyd, B. J., 1 Jan 2019, In : Molecular Pharmaceutics. 16, 4, p. 1658-1668 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Nucleation of β-rich oligomers and β-barrels in the early aggregation of human islet amyloid polypeptide

Sun, Y., Kakinen, A., Xing, Y., Pilkington, E. H., Davis, T. P., Ke, P. C. & Ding, F., 1 Feb 2019, In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1865, 2, p. 434-444 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Physical and toxicological profiles of human IAPP amyloids and plaques

Kakinen, A., Sun, Y., Javed, I., Faridi, A., Pilkington, E. H., Faridi, P., Purcell, A. W., Zhou, R., Ding, F., Lin, S., Ke, P. C. & Davis, T. P., 15 Jan 2019, In : Science Bulletin. 64, 1, p. 26-35 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Promoting intestinal lymphatic transport targets a liver-X receptor (LXR) agonist (WAY-252,623) to lymphocytes and enhances immunomodulation

Cao, E., Lindgren, A., Martinsson, S., Hu, L., Lindfors, L., Sigfridsson, K., Skantze, U., Michaëlsson, E., Trevaskis, N. L. & Porter, C. J. H., 28 Feb 2019, In : Journal of Controlled Release. 296, p. 29-39 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Revisiting dispersible milk-drug tablets as a solid lipid formulation in the context of digestion

Binte Abu Bakar, S. Y., Salim, M., Clulow, A. J., Hawley, A. & Boyd, B. J., 10 Jan 2019, In : International Journal of Pharmaceutics. 554, p. 179-189 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Synthesis and identification of novel pryidazinylpyrazolone based diazo compounds as inhibitors of human islet amyloid polypeptide aggregation

Bin Farrukh, S. U., Javed, I., Ather, A. Q., Emwas, A-H., Alazmi, M., Gao, X., Chotana, G. A., Davis, T. P., Ke, P. C. & Saleem, R. S. Z., Mar 2019, In : Bioorganic Chemistry. 84, p. 339-346 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Understanding the Impacts of Surface Compositions on the In-Vitro Dissolution and Aerosolization of Co-Spray-Dried Composite Powder Formulations for Inhalation

Mangal, S., Xu, R., Park, H., Zemlyanov, D., Shetty, N., Lin, Y-W., Morton, D., Chan, H-K., Li, J. & Zhou, T. Q., 1 Jan 2019, In : Pharmaceutical Research. 36, 15 p.

Research output: Contribution to journalArticleResearchpeer-review

2018

A closer look at the behaviour of milk lipids during digestion

Clulow, A. J., Salim, M., Hawley, A. & Boyd, B. J., 1 Mar 2018, In : Chemistry and Physics of Lipids. 211, p. 107-116 10 p.

Research output: Contribution to journalArticleResearchpeer-review

A Comparative Study of Outer Membrane Proteome between Paired Colistin-Susceptible and Extremely Colistin-Resistant Klebsiella pneumoniae Strains

Jasim, R., Baker, M. A., Zhu, Y., Han, M., Schneider-Futschik, E. K., Hussein, M., Hoyer, D., Li, J. & Velkov, T., 1 Jan 2018, (Accepted/In press) In : ACS Infectious Diseases. 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Acute or Delayed Systemic Administration of Human Amnion Epithelial Cells Improves Outcomes in Experimental Stroke

Evans, M. A., Lim, R., Kim, H. A., Chu, H. X., Gardiner-Mann, C. V., Taylor, K. W. E., Chan, C. T., Brait, V. H., Lee, S., Dinh, Q. N., Vinh, A., Phan, T. G., Srikanth, V. K., Ma, H., Arumugam, T. V., Fann, D. Y., Poh, L., Hunt, C. P. J., Pouton, C. W., Haynes, J. M. & 12 othersSelemidis, S., Kwan, W., Teo, L., Bourne, J. A., Neumann, S., Young, S., Gowing, E. K., Drummond, G. R., Clarkson, A. N., Wallace, E. M., Sobey, C. G. & Broughton, B. R. S., 1 Mar 2018, In : Stroke. 49, 3, p. 700-709 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Alterations of Metabolic and Lipid Profiles in Polymyxin-Resistant Pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Anderson, D., Shen, H-H., Tsuji, B., Gutu, A. D., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jun 2018, In : Antimicrobial Agents and Chemotherapy. 62, 6, 14 p., e02656-17.

Research output: Contribution to journalArticleResearchpeer-review

Assessment and modelling of antibacterial combination regimens

Rao, G. G., Li, J., Garonzik, S. M., Nation, R. L. & Forrest, A., Jul 2018, In : Clinical Microbiology and Infection. 24, 7, p. 689-696 8 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

A tunable one-pot three-component synthesis of an 125I and Gd-labelled star polymer nanoparticle for hybrid imaging with MRI and nuclear medicine

Esser, L., Lengkeek, N. A., Moffat, B. A., Vu, M. N., Greguric, I., Quinn, J. F., Davis, T. P. & Whittaker, M. R., 7 Jul 2018, In : Polymer Chemistry. 9, 25, p. 3528-3535 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Bulk and dispersed aqueous behaviour of an endogenous lipid, selachyl alcohol: Effect of Tween 80 and Pluronic F127 on nanostructure

Younus, M., Hawley, A., Boyd, B. J. & Rizwan, S. B., 1 Sep 2018, In : Colloids and Surfaces B: Biointerfaces. 169, p. 135-142 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Clickable Cubosomes for Antibody-Free Drug Targeting and Imaging Applications

Alcaraz, N., Liu, Q., Hanssen, E., Johnston, A. & Boyd, B. J., 17 Jan 2018, In : Bioconjugate Chemistry. 29, 1, p. 149-157 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cognitive benefits of lithium chloride in APP/PS1 mice are associated with enhanced brain clearance of β-amyloid

Pan, Y., Short, J. L., Newman, S. A., Choy, K. H. C., Tiwari, D., Yap, C., Senyschyn, D., Banks, W. A. & Nicolazzo, J. A., 2018, (Accepted/In press) In : Brain, Behavior, and Immunity. 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Combating Carbapenem-Resistant Acinetobacter baumannii by an Optimized Imipenem-plus-Tobramycin Dosage Regimen: Prospective Validation via Hollow-Fiber Infection and Mathematical Modeling

Landersdorfer, C. B., Yadav, R., Rogers, K. E., Kim, T. H., Shin, B. S., Boyce, J. D., Nation, R. L. & Bulitta, J. B., 1 Apr 2018, In : Antimicrobial Agents and Chemotherapy. 62, 4, 8 p., e02053-17.

Research output: Contribution to journalArticleResearchpeer-review

Comparative analysis of phosphoethanolamine transferases involved in polymyxin resistance across 10 clinically relevant Gram-negative bacteria

Huang, J., Zhu, Y., Han, M., Li, M., Song, J., Velkov, T., Li, C. & Li, J., 1 Apr 2018, In : International Journal of Antimicrobial Agents. 51, 4, p. 586-593 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Comparison of the composition and in vitro activity of polymyxin B products

Diep, J. K., Covelli, J., Sharma, R., Ruszaj, D. M., Kaye, K. S., Li, J., Straubinger, R. M. & Rao, G. G., 25 May 2018, (Accepted/In press) In : International Journal of Antimicrobial Agents. 7 p.

Research output: Contribution to journalArticleResearchpeer-review

Continued positive development of JCIS

Bandoz, T., Berti, D., Boyd, B., Eastoe, J., Hubbard, A., Lopez-Quintela, A., Lu, M., Malmsten, M. & Zheng, G., 1 Nov 2018, In : Journal of Colloid and Interface Science. 529, p. A1-A2

Research output: Contribution to journalEditorialOtherpeer-review

Open Access
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Controlling Nanomaterial Size and Shape for Biomedical Applications via Polymerization-Induced Self-Assembly

Khor, S. Y., Quinn, J. F., Whittaker, M. R., Truong, N. P. & Davis, T. P., 1 Jan 2018, (Accepted/In press) In : Macromolecular Rapid Communications. 22 p.

Research output: Contribution to journalArticleResearchpeer-review

Correction to: Polymyxin B causes DNA damage in HK-2 cells and mice (Archives of Toxicology, (2018), 92, 7, (2259-2271), 10.1007/s00204-018-2192-1)

Yun, B., Zhang, T., Azad, M. A. K., Wang, J., Nowell, C. J., Kalitsis, P., Velkov, T., Hudson, D. F. & Li, J., 1 Jul 2018, In : Archives of Toxicology. 92, 7, p. 2273-2274 2 p.

Research output: Contribution to journalComment / DebateOtherpeer-review

Open Access
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Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution

Larnaudie, S. C., Sanchis, J., Nguyen, T. H., Peltier, R., Catrouillet, S., Brendel, J. C., Porter, C. J. H., Jolliffe, K. A. & Perrier, S., 1 Sep 2018, In : Biomaterials. 178, p. 570-582 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Cyclic Peptide-Polymer Nanotubes as Efficient and Highly Potent Drug Delivery Systems for Organometallic Anticancer Complexes

Larnaudie, S. C., Brendel, J. C., Romero-Canelón, I., Sanchez-Cano, C., Catrouillet, S., Sanchis, J., Coverdale, J. P. C., Song, J. I., Habtemariam, A., Sadler, P. J., Jolliffe, K. A. & Perrier, S., 8 Jan 2018, In : Biomacromolecules. 19, 1, p. 239-247 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Differences in suppression of regrowth and resistance despite similar initial bacterial killing for meropenem and piperacillin/tazobactam against Pseudomonas aeruginosa and Escherichia coli

Bergen, P. J., Bulitta, J. B., Sime, F. B., Lipman, J., McGregor, M. J., Millen, N., Paterson, D. L., Kirkpatrick, C. M. J., Roberts, J. A. & Landersdorfer, C. B., 1 May 2018, In : Diagnostic Microbiology and Infectious Disease. 91, 1, p. 69-76 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Distribution of therapeutic proteins into thoracic lymph after intravenous administration is protein size-dependent and primarily occurs within the liver and mesentery

Yadav, P., McLeod, V. M., Nowell, C. J., Selby, L. I., Johnston, A. P. R., Kaminskas, L. M. & Trevaskis, N. L., 28 Feb 2018, In : Journal of Controlled Release. 272, p. 17-28 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Doxorubicin Conjugation and Drug Linker Chemistry Alter the Intravenous and Pulmonary Pharmacokinetics of a PEGylated Generation 4 Polylysine Dendrimer in Rats

Leong, N. J., Mehta, D., McLeod, V. M., Kelly, B. D., Pathak, R., Owen, D. J., Porter, C. J. H. & Kaminskas, L. M., 1 Sep 2018, In : Journal of Pharmaceutical Sciences. 107, 9, p. 2509-2513 5 p.

Research output: Contribution to journalArticleResearchpeer-review

Drug nanocrystallisation within liposomes

Li, T., Cipolla, D., Rades, T. & Boyd, B. J., 28 Oct 2018, In : Journal of Controlled Release. 288, p. 96-110 15 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Effect of Permeation Enhancers on the Buccal Permeability of Nicotine: Ex vivo Transport Studies Complemented by MALDI MS Imaging

Marxen, E., Jin, L., Jacobsen, J., Janfelt, C., Hyrup, B. & Nicolazzo, J. A., 1 Mar 2018, In : Pharmaceutical Research. 35, 3, 12 p., 70.

Research output: Contribution to journalArticleResearchpeer-review

Elucidating the Influences of Size, Surface Chemistry, and Dynamic Flow on Cellular Association of Nanoparticles Made by Polymerization-Induced Self-Assembly

Khor, S. Y., Vu, M. N., Pilkington, E. H., Johnston, A. P. R., Whittaker, M. R., Quinn, J. F., Truong, N. P. & Davis, T. P., 23 Aug 2018, In : Small. 14, 34, 13 p., 1801702.

Research output: Contribution to journalArticleResearchpeer-review

Elucidating the pharmacokinetics/pharmacodynamics of aerosolized colistin against multidrug-resistant acinetobacter baumannii and klebsiella pneumoniae in a mouse lung infection model

Lin, Y-W., Zhou, Q. T., Han, M-L., Chen, K., Onufrak, N. J., Wang, J., Turnidge, J. D., Howden, B. P., Forrest, A., Chan, H. K. & Li, J., 1 Feb 2018, In : Antimicrobial Agents and Chemotherapy. 62, 2, 9 p., e01790.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Elucidation of the pharmacokinetic/pharmacodynamic determinants of fosfomycin activity against Pseudomonas aeruginosa using a dynamic in vitro model

Bilal, H., Peleg, A. Y., McIntosh, M. P., Styles, I. K., Hirsch, E. B., Landersdorfer, C. B. & Bergen, P. J., 1 Jun 2018, In : Journal of Antimicrobial Chemotherapy. 73, 6, p. 1570-1578 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Emergence of high-level colistin resistance in an acinetobacter baumannii clinical isolate mediated by inactivation of the global regulator H-NS

Lucas, D. D., Crane, B., Wright, A., Han, M-L., Moffatt, J., Bulach, D., Gladman, S. L., Powell, D., Aranda, J., Seemann, T., Machado, D., Pacheco, T., Marques, T., Viveiros, M., Nation, R., Li, J., Harper, M. & Boyce, J. D., 1 Jul 2018, In : Antimicrobial Agents and Chemotherapy. 62, 7, 17 p., e02442-17.

Research output: Contribution to journalArticleResearchpeer-review

Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations

Williams, H. D., Ford, L., Han, S., Tangso, K. J., Lim, S., Shackleford, D. M., Vodak, D. T., Benameur, H., Pouton, C. W., Scammells, P. J. & Porter, C. J. H., 1 Jan 2018, In : Molecular Pharmaceutics. 15, 12, p. 5678−5696 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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Experimental study of the deformation and breakage of 3D printed agglomerates: Effects of packing density and inter-particle bond strength

Ge, R., Ghadiri, M., Bonakdar, T., Zhou, Z., Larson, I. & Hapgood, K., 1 Dec 2018, In : Powder Technology. 340, p. 299-310 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Exploiting macromolecular design to optimize the antibacterial activity of alkylated cationic oligomers

Grace, J. L., Schneider-Futschik, E. K., Elliott, A. G., Amado, M., Truong, N. P., Cooper, M. A., Li, J., Davis, T. P., Quinn, J. F., Velkov, T. & Whittaker, M. R., 25 Oct 2018, (Accepted/In press) In : Biomacromolecules. 12 p.

Research output: Contribution to journalArticleResearchpeer-review