Research Output 1975 2019

2019

3,3′-Disubstituted 5,5′-Bi(1,2,4-triazine) Derivatives with Potent in Vitro and in Vivo Antimalarial Activity

Xue, L., Shi, D. H., Harjani, J. R., Huang, F., Beveridge, J. G., Dingjan, T., Ban, K., Diab, S., Duffy, S., Lucantoni, L., Fletcher, S., Chiu, F. C. K., Blundell, S., Ellis, K., Ralph, S. A., Wirjanata, G., Teguh, S., Noviyanti, R., Chavchich, M., Creek, D. & 10 others, Price, R. N., Marfurt, J., Charman, S. A., Cuellar, M. E., Strasser, J. M., Dahlin, J. L., Walters, M. A., Edstein, M. D., Avery, V. M. & Baell, J. B., 1 Jan 2019, In : Journal of Medicinal Chemistry. 62, 5, p. 2485-2498 14 p.

Research output: Contribution to journalArticleResearchpeer-review

A 30 kDa polyethylene glycol-enfuvirtide complex enhances the exposure of enfuvirtide in lymphatic viral reservoirs in rats

Kaminskas, L. M., Williams, C. C., Leong, N. J., Chan, L. J., Butcher, N. J., Feeney, O. M., Porter, C. J. H., Tyssen, D., Tachedjian, G. & Ascher, D. B., 1 Apr 2019, In : European Journal of Pharmaceutics and Biopharmaceutics. 137, p. 218-226 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Advances in Microfluidic Blood–Brain Barrier (BBB) Models

Oddo, A., Peng, B., Tong, Z., Wei, Y., Tong, W. Y., Thissen, H. & Voelcker, N. H., 23 May 2019, (Accepted/In press) In : Trends in Biotechnology. 20 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Advances in Porous Silicon–Based Nanomaterials for Diagnostic and Therapeutic Applications

Tieu, T., Alba Martin, M., Elnathan, R., Cifuentes-Rius, A. & Voelcker, N. H., Jan 2019, In : Advanced Therapeutics. 2, 1, 25 p., 1800095.

Research output: Contribution to journalReview ArticleResearchpeer-review

Open Access
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1 Citation (Scopus)

A fluorogenic probe based on chelation-hydrolysis-enhancement mechanism for visualizing Zn2+ in Parkinson's disease models

Zhang, G., Zhao, Y., Peng, B., Li, Z., Xu, C., Liu, Y., Zhang, C., Voelcker, N. H., Li, L. & Huang, W., 14 Apr 2019, In : Journal of Materials Chemistry B. 7, 14, p. 2252-2260 9 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

A ligand-induced structural change in fatty acid-binding protein 1 is associated with potentiation of peroxisome proliferator-activated receptor α agonists

Patil, R., Mohanty, B., Liu, B., Chandrashekaran, I. R., Headey, S. J., Williams, M. L., Clements, C. S., Ilyichova, O., Doak, B. C., Genissel, P., Weaver, R., Vuillard, L., Halls, M. L., Porter, C. J. H. & Scanlon, M. J., 8 Mar 2019, In : Journal of Biological Chemistry. 294, 10, p. 3720-3734 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Amphiphilic surface chemistry of fullerenols is necessary for inhibiting the amyloid aggregation of alpha-synuclein NACore

Sun, Y., Kakinen, A., Zhang, C., Yang, Y., Faridi, A., Davis, T. P., Cao, W., Ke, P. C. & Ding, F., 28 Jun 2019, In : Nanoscale. 11, 24, p. 11933-11945 13 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Amyloid Self-Assembly of hIAPP8-20 via the Accumulation of Helical Oligomers, α-Helix to β-Sheet Transition, and Formation of β-Barrel Intermediates

Sun, Y., Kakinen, A., Xing, Y., Faridi, P., Nandakumar, A., Purcell, A. W., Davis, T. P., Ke, P. C. & Ding, F., May 2019, In : Small. 15, 18, 10 p., 1805166.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL

Suys, E. J. A., Warren, D. B., Pham, A. C., Nowell, C. J., Clulow, A. J., Benameur, H., Porter, C. J. H., Pouton, C. W. & Chalmers, D. K., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 193-204 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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An optimised Cu(0)-RDRP approach for the synthesis of lipidated oligomeric vinyl azlactone: toward a versatile antimicrobial materials screening platform

Grace, J. L., Amado, M., Reid, J. C., Elliott, A. G., Landersdorfer, C. B., Truong, N. P., Kempe, K., Cooper, M. A., Davis, T. P., Montembault, V., Pascual, S., Fontaine, L., Velkov, T., Quinn, J. F. & Whittaker, M. R., 21 Nov 2019, In : Journal of Materials Chemistry B. 7, 43, p. 6796-6809 14 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M. S., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 others, Failes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 Jan 2019, In : Oncogene. 38, 20, p. 3824-3842 19 p.

Research output: Contribution to journalArticleResearchpeer-review

Open Access
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15 Citations (Scopus)

An Overview of 3D Printing Technologies for Soft Materials and Potential Opportunities for Lipid-based Drug Delivery Systems

Vithani, K., Goyanes, A., Jannin, V., Basit, A. W., Gaisford, S. & Boyd, B. J., 1 Jan 2019, In : Pharmaceutical Research. 36, 1, 20 p., 4.

Research output: Contribution to journalReview ArticleResearchpeer-review

A pH-responsive nanoparticle targets the neurokinin 1 receptor in endosomes to prevent chronic pain

Ramirez Garcia, P. D., Retamal, J. S., Shenoy, P., Imlach, W., Sykes, M., Truong, N., Constandil, L., Pelissier, T., Nowell, C. J., Khor, S. Y., Layani, L. M., Lumb, C., Poole, D. P., Lieu, T., Stewart, G. D., Mai, Q. N., Jensen, D. D., Latorre, R., Scheff, N. N., Schmidt, B. L. & 5 others, Quinn, J. F., Whittaker, M. R., Veldhuis, N. A., Davis, T. P. & Bunnett, N. W., 4 Nov 2019, (Accepted/In press) In : Nature Nanotechnology. 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Application of Low-Frequency Raman Scattering Spectroscopy to Probe in Situ Drug Solubilization in Milk during Digestion

Salim, M., Fraser-Miller, S. J., Sutton, J. J., Berzinš, K., Hawley, A., Clulow, A. J., Beilles, S., Gordon, K. C. & Boyd, B. J., 2 May 2019, In : Journal of Physical Chemistry Letters. 10, 9, p. 2258-2263 6 p.

Research output: Contribution to journalArticleResearchpeer-review

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3 Citations (Scopus)

A Proof of Concept for 3D Printing of Solid Lipid-Based Formulations of Poorly Water-Soluble Drugs to Control Formulation Dispersion Kinetics

Vithani, K., Goyanes, A., Jannin, V., Basit, A. W., Gaisford, S. & Boyd, B. J., 1 Jul 2019, In : Pharmaceutical Research. 36, 7, 13 p., 102.

Research output: Contribution to journalArticleResearchpeer-review

A sequential native chemical ligation-thiol-Michael addition strategy for polymer-polymer ligation

Rajakanthan, A., Jongh, P. A. J. M. D., Town, J. S., Wilson, P. & Kempe, K., 14 Oct 2019, In : Polymer Chemistry. 10, 38, p. 5242-5250 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Carboxylated Cy5-Labeled Comb Polymers Passively Diffuse the Cell Membrane and Target Mitochondria

Mahmoud, A. M., De Jongh, P. A. J. M., Briere, S., Chen, M., Nowell, C. J., Johnston, A. P. R., Davis, T. P., Haddleton, D. M. & Kempe, K., 28 Aug 2019, In : ACS Applied Materials and Interfaces. 11, 34, p. 31302-31310 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Cellular Deformations Induced by Conical Silicon Nanowire Arrays Facilitate Gene Delivery

Chen, Y., Aslanoglou, S., Gervinskas, G., Abdelmaksoud, H., Voelcker, N. H. & Elnathan, R., 10 Oct 2019, (Accepted/In press) In : Small. 1904819.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Characterization of Hypermutator Pseudomonas aeruginosa Isolates from Patients with Cystic Fibrosis in Australia

Rees, V. E., Deveson Lucas, D. S., López-Causapé, C., Huang, Y., Kotsimbos, T., Bulitta, J. B., Rees, M. C., Barugahare, A., Peleg, A. Y., Nation, R. L., Oliver, A., Boyce, J. D. & Landersdorfer, C. B., 1 Apr 2019, In : Antimicrobial Agents and Chemotherapy. 63, 4, 11 p., e02538-18.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Co-delivery of RNAi and chemokine by polyarginine nanocapsules enables the modulation of myeloid-derived suppressor cells

Ledo, A. M., Sasso, M. S., Bronte, V., Marigo, I., Boyd, B. J., Garcia-Fuentes, M. & Alonso, M. J., 10 Feb 2019, In : Journal of Controlled Release. 295, p. 60-73 14 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Colloidal aspects of dispersion and digestion of self-dispersing lipid-based formulations for poorly water-soluble drugs

Vithani, K., Jannin, V., Pouton, C. W. & Boyd, B. J., 2019, In : Advanced Drug Delivery Reviews. 142, p. 16-34 19 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in pseudomonas aeruginosa

Han, M-L., Zhu, Y., Creek, D. J., Lin, Y-W., Gutu, A. D., Hertzog, P., Purcell, T., Shen, H-H., Moskowitz, S. M., Velkov, T. & Li, J., 1 Jan 2019, In : mSystems. 4, 1, 18 p., e00149-18.

Research output: Contribution to journalArticleResearchpeer-review

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Comparative metabolomics reveals key pathways associated with the synergistic killing of colistin and sulbactam combination against multidrug-resistant Acinetobacter baumannii

Han, M-L., Liu, X., Velkov, T., Lin, Y-W., Zhu, Y., Creek, D. J., Barlow, C. K., Yu, H. H., Zhou, Z., Zhang, J. & Li, J., 4 Jul 2019, In : Frontiers in Pharmacology. 10, 11 p., 754.

Research output: Contribution to journalArticleResearchpeer-review

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13 Citations (Scopus)

Controlling Nanomaterial Size and Shape for Biomedical Applications via Polymerization-Induced Self-Assembly

Khor, S. Y., Quinn, J. F., Whittaker, M. R., Truong, N. P. & Davis, T. P., Jan 2019, In : Macromolecular Rapid Communications. 40, 2, 22 p., 1800438.

Research output: Contribution to journalArticleResearchpeer-review

Controlling the size and shape of liposomal ciprofloxacin nanocrystals by varying the lipid bilayer composition and drug to lipid ratio

Li, T., Clulow, A. J., Nowell, C. J., Hawley, A., Cipolla, D., Rades, T. & Boyd, B. J., 1 Nov 2019, In : Journal of Colloid and Interface Science. 555, p. 361-372 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Deposition of aminomalononitrile-based films: Kinetics, chemistry, and morphology

Toh, R. J., Evans, R., Thissen, H., Voelcker, N. H., D'ischia, M. & Ball, V., 30 Jul 2019, In : Langmuir. 35, 30, p. 9896-9903 8 p.

Research output: Contribution to journalArticleResearchpeer-review

6 Citations (Scopus)

Deuterated phytantriol – A versatile compound for probing material distribution in liquid crystalline lipid phases using neutron scattering

Yepuri, N. R., Clulow, A. J., Prentice, R. N., Gilbert, E. P., Hawley, A., Rizwan, S. B., Boyd, B. J. & Darwish, T. A., 15 Jan 2019, In : Journal of Colloid and Interface Science. 534, p. 399-407 9 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Development of a Shape-Controlled H2S Delivery System Using Epoxide-Functional Nanoparticles

Yu, S. H., Esser, L., Khor, S. Y., Senyschyn, D., Veldhuis, N. A., Whittaker, M. R., Ercole, F., Davis, T. P. & Quinn, J. F., 2019, In : Journal of Polymer Science, Part A: Polymer Chemistry. 57, 18, p. 1982–1993 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential Effects of TPM, A Phosphorylated Tocopherol Mixture, and Other Tocopherol Derivatives as Excipients for Enhancing the Solubilization of Co-Enzyme Q10 as a Lipophilic Drug During Digestion of Lipid- Based Formulations

Pham, A., Gavin, P. D., Libinaki, R., Ramirez, G., Khan, J. T. & Boyd, B. J., 1 Jan 2019, In : Current Drug Delivery. 16, 7, p. 628-636 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential functionalisation of the internal and external surfaces of carbon-stabilised nanoporous silicon

Alba, M., Robin, M., Menzies, D., Gengenbach, T. R., Prieto-Simon, B. & Voelcker, N. H., 15 Jun 2019, In : Chemical Communications. 55, 55, p. 8001-8004 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Differential Roles of Plasma Protein Corona on Immune Cell Association and Cytokine Secretion of Oligomeric and Fibrillar Beta-Amyloid

Faridi, A., Yang, W., Kelly, H. G., Wang, C., Faridi, P., Purcell, A. W., Davis, T. P., Chen, P., Kent, S. J. & Ke, P. C., 11 Nov 2019, In : Biomacromolecules. 20, 11, p. 4208-4217 10 p.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Differentiation of Rat Mesenchymal Stem Cells toward Osteogenic Lineage on Extracellular Matrix Protein Gradients

Rasi Ghaemi, S., Delalat, B., Cavallaro, A., Mierczynska-Vasilev, A., Vasilev, K. & Voelcker, N. H., 1 Sep 2019, In : Advanced Healthcare Materials. 8, 17, 11 p., 1900595.

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Direct Comparison of Standard Transmission Electron Microscopy and Cryogenic-TEM in Imaging Nanocrystals Inside Liposomes

Li, T., Nowell, C. J., Cipolla, D., Rades, T. & Boyd, B. J., 1 Apr 2019, In : Molecular Pharmaceutics. 16, 4, p. 1775-1781 7 p.

Research output: Contribution to journalArticleResearchpeer-review

7 Citations (Scopus)

Discovery and Validation of Clinical Biomarkers of Cancer: A Review Combining Metabolomics and Proteomics

Srivastava, A. & Creek, D. J., May 2019, In : Proteomics. 19, 10, 9 p., 1700448.

Research output: Contribution to journalArticleResearchpeer-review

Editorial

Mohd Amin, M. C. I., Kiew, L. V. & Boyd, B., 15 Apr 2019, In : Drug Delivery and Translational Research. 9, 2, p. 417-417 1 p.

Research output: Contribution to journalEditorialOtherpeer-review

Open Access

Engineered nano-bio interfaces for intracellular delivery and sampling: Applications, agency and artefacts

Lestrell, E., Patolsky, F., Voelcker, N. H. & Elnathan, R., 2019, (Accepted/In press) In : Materials Today. p. 1-18 18 p.

Research output: Contribution to journalReview ArticleResearchpeer-review

Engineering Biocoatings to Prolong Drug Release from Supraparticles

Ma, Y., Cortez-Jugo, C., Li, J., Lin, Z., Richardson, R. T., Han, Y., Zhou, J., Björnmalm, M., Feeney, O. M., Zhong, Q. Z., Porter, C. J. H., Wise, A. K. & Caruso, F., 1 Jan 2019, In : Biomacromolecules. 20, 9, p. 3425-3434 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Engineering Organic/Inorganic Nanohybrids through RAFT Polymerization for Biomedical Applications

Huang, X., Hu, J., Li, Y., Xin, F., Qiao, R. & Davis, T. P., 1 Jan 2019, (Accepted/In press) In : Biomacromolecules.

Research output: Contribution to journalArticleResearchpeer-review

Experimental and theoretical demonstrations of ultraviolet absorption enhancement in porous nano-membrane graphene

Kasry, A., Fadlallah, M. M., Voelcker, N. H. & Maarouf, A. A., 1 Dec 2019, In : Carbon. 155, p. 65-70 6 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Four Decades of β-Lactam Antibiotic Pharmacokinetics in Cystic Fibrosis

Bulitta, J. B., Jiao, Y., Drescher, S. K., Oliver, A., Louie, A., Moya, B., Tao, X., Wittau, M., Tsuji, B. T., Zavascki, A. P., Shin, B. S., Drusano, G. L., Sörgel, F. & Landersdorfer, C. B., 6 Feb 2019, In : Clinical Pharmacokinetics. 58, 2, p. 143-156 14 p.

Research output: Contribution to journalArticleResearchpeer-review

3 Citations (Scopus)

Functional Brush Poly(2-ethyl-2-oxazine)s: Synthesis by CROP and RAFT, Thermoresponsiveness and Grafting onto Iron Oxide Nanoparticles

Klein, T., Parkin, J., de Jongh, P. A. J. M., Esser, L., Sepehrizadeh, T., Zheng, G., De Veer, M., Alt, K., Hagemeyer, C. E., Haddleton, D. M., Davis, T. P., Thelakkat, M. & Kempe, K., May 2019, In : Macromolecular Rapid Communications. 40, 10, 6 p., 1800911.

Research output: Contribution to journalArticleResearchpeer-review

9 Citations (Scopus)

Functional Liquid Metal Nanoparticles Produced by Liquid-Based Nebulization

Tang, S. Y., Qiao, R., Lin, Y., Li, Y., Zhao, Q., Yuan, D., Yun, G., Guo, J., Dickey, M. D., Huang, T. J., Davis, T. P., Kalantar-Zadeh, K. & Li, W., Feb 2019, In : Advanced Materials Technologies. 4, 2, 9 p., 1800420.

Research output: Contribution to journalArticleResearchpeer-review

Global Metabolic Analyses of Acinetobacter baumannii

Maifiah, M. H. M., Velkov, T., Creek, D. J. & Li, J., 1 Jan 2019, Acinetobacter baumannii: Methods and Protocols. Biswas, I. & Rather, P. N. (eds.). 1 ed. Humana Press, p. 321-328 8 p. (Methods in Molecular Biology; vol. 1946).

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Researchpeer-review

4 Citations (Scopus)

Gold microneedles fabricated by casting of gold ink used for urea sensing

Senel, M., Dervisevic, M. & Voelcker, N. H., 15 May 2019, In : Materials Letters. 243, p. 50-53 4 p.

Research output: Contribution to journalArticleResearchpeer-review

Graphene quantum dots rescue protein dysregulation of pancreatic β-cells exposed to human islet amyloid polypeptide

Faridi, A., Sun, Y., Mortimer, M., Aranha, R. R., Nandakumar, A., Li, Y., Javed, I., Kakinen, A., Fan, Q., Purcell, A. W., Davis, T. P., Ding, F., Faridi, P. & Ke, P. C., Nov 2019, In : Nano Research. 12, 11, p. 2827-2834 8 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Impact of Ferroquine on the Solubilization of Artefenomel (OZ439) during in Vitro Lipolysis in Milk and Implications for Oral Combination Therapy for Malaria

Salim, M., Khan, J., Ramirez, G., Murshed, M., Clulow, A. J., Hawley, A., Ramachandruni, H., Beilles, S. & Boyd, B. J., 1 Jan 2019, In : Molecular Pharmaceutics. 16, 4, p. 1658-1668 11 p.

Research output: Contribution to journalArticleResearchpeer-review

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Impact of reduced P-glycoprotein function on digoxin concentrations in patients with dementia

Ali, I., Guidone, D., Nicolazzo, J. A. & Brouwer, K. L. R., 1 Jan 2019, In : British Journal of Clinical Pharmacology. 85, 10, p. 2351-2359 9 p.

Research output: Contribution to journalArticleResearchpeer-review

4 Citations (Scopus)

Importance of Thermally Induced Aggregation on 19 F Magnetic Resonance Imaging of Perfluoropolyether-Based Comb-Shaped Poly(2-oxazoline)s

Zhang, C., Sanchez, R. J. P., Fu, C., Clayden-Zabik, R., Peng, H., Kempe, K. & Whittaker, A. K., 14 Jan 2019, In : Biomacromolecules. 20, 1, p. 365-374 10 p.

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Improvement in the Predicted Partitioning of Alcohol and Polyethylene Oxide Groups Between Water and Octanol (logP) in Molecular Dynamics Simulations

Warren, D. B., McPhee, E., Birru, W. A., Benameur, H., Chalmers, D. K. & Pouton, C. W., 1 Jan 2019, In : Journal of Pharmaceutical Sciences. 108, 1, p. 214-222 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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