Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2008 2020

Research Output 1994 2017

Antimalarial efficacy of MMV390048, an inhibitor of Plasmodium phosphatidylinositol 4-kinase

Paquet, T. , Le Manach, C. , Cabrera, D. G. , Younis, Y. , Henrich, P. P. , Abraham, T. S. , Lee, M. C. S. , Basak, R. , Ghidelli-Disse, S. , Lafuente-Monasterio, M. J. , Bantscheff, M. , Ruecker, A. , Blagborough, A. M. , Zakutansky, S. E. , Zeeman, A-M. , White, K. L. , Shackleford, D. M. , Mannila, J. , Morizzi, J. , Scheurer, C. & 1 others Charman, S. A. 26 Apr 2017 In : Science Translational Medicine. 9, 387, 14 p., eaad9735

Research output: Contribution to journalArticle

Antimalarial Inhibitors Targeting Serine Hydroxymethyltransferase (SHMT) with in Vivo Efficacy and Analysis of their Binding Mode Based on X-ray Cocrystal Structures

Schwertz, G. , Witschel, M. C. , Rottmann, M. , Bonnert, R. , Leartsakulpanich, U. , Chitnumsub, P. , Jaruwat, A. , Ittarat, W. , Schäfer, A. , Aponte, R. A. , Charman, S. A. , White, K. L. , Kundu, A. , Sadhukhan, S. , Lloyd, M. , Freiberg, G. M. , Srikumaran, M. , Siggel, M. , Zwyssig, A. , Chaiyen, P. & 1 others Diederich, F. 22 Jun 2017 In : Journal of Medicinal Chemistry. 60, 12, p. 4840-4860 21 p.

Research output: Contribution to journalArticle

A tetraoxane-based antimalarial drug candidate that overcomes PfK13-C580Y dependent artemisinin resistance

O'Neill, P. M. , Amewu, R. K. , Charman, S. A. , Sabbani, S. , Gnädig, N. F. , Straimer, J. , Fidock, D. A. , Shore, E. R. , Roberts, N. L. , Wong, M. H. L. , Hong, W. D. , Pidathala, C. , Riley, C. , Murphy, B. , Aljayyoussi, G. , Gamo, F. J. , Sanz, L. , Rodrigues, J. , Cortes, C. G. , Herreros, E. & 2 others Ryan, E. & Shackleford, D. M. 24 May 2017 In : Nature Communications. 8, 10 p., 15159

Research output: Contribution to journalArticle

Open Access
File

Activities 2011 2011

  • 4 Submissions to industry or govt committees, commissions and inquiries

Centre for Drug Candidate Optimisation

Karen White (Member)
1 Dec 2011

Activity: Submissions to industry or govt committees, commissions and inquiries

Centre for Drug Candidate Optimisation

Shackleford, D. (Member)
30 Nov 2011

Activity: Submissions to industry or govt committees, commissions and inquiries

Centre for Drug Candidate Optimisation

Chiu, F. C. K. (Member)
29 Nov 2011

Activity: Submissions to industry or govt committees, commissions and inquiries