Central Clinical School

Projects

Projects per year

2000 2028

• 15 Curtailed
• 26 Not started
• 518 Active
• 1140 Finished

Projects per year

Search results

• Cardiorespiratory function as a non-invasive biomarker for detecting seizures with artificial intelligence: Utilising data from long-term patient recordings from an epilepsy monitoring unit

  O'Brien, T., Kwan, P., Sivathamboo, S., Perucca, P., Ge, Z., Le, T., Phung, D., Bonnington, P. & Piccenna, L.

  8/04/19 → 8/04/20

  Project: Research

• An Open-Label Study to Assess The Efficacy and Safety of LM011 In Subjects Diagnosed With Non-Alcoholic Steatohepatitis (NASH).

  Roberts, S.

  16/04/19 → 31/12/19

  Project: Research

• A Randomized, Controlled, Open-Label, Rater-Blinded, Phase 3b Study of the Efficacy, Safety, and Tolerability of 6-Week Extended Interval Dosing of Natalizumab (BG00002) in Subjects With Relapsing-Remitting Multiple Sclerosis Switching from Treatment with 4-Week Natalizumab Standard Interval Dosing (SID) in Relation to Continued SID Treatment.

  Van Der Walt, A.

  16/04/19 → 31/12/24

  Project: Research

• Breath Control Training for Non-Epileptic Seizures

  Winton-Brown, T. & Burn, K.

  30/04/19 → 30/04/20

  Project: Research

• A Cognitive-Mobility Stress Test To Detect MCI and Risk of Conversion to Dementia

  Callisaya, M.

  Dementia Australia Research Foundation Ltd

  1/05/19 → 1/05/21

  Project: Research

• Transforming the treatment landscape in elderly Acute Myeloid Leukaemia (AML)

  Wei, A., Bohlander, S. K., Reynolds, J. & Levis, M.

  1/05/19 → 31/12/22

  Project: Research

• Establishing the current state of teaching and knowledge of Interventional Radiology amongst Australian Medical students

  Clements, W. & Goh, G.

  1/05/19 → …

  Project: Research

• New approaches to detect drug resistant superbugs

  Wood, B., Heraud, P. & Peleg, A.

  3/05/19 → 2/11/20

  Project: Research

• A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study of Durvalumab Monotherapy or in Combination with Bevacizumab as Adjuvant Therapy in Patients with Hepatocellular Carcinoma who are at High Risk of Recurrence After Curative Hepatic Resection or Ablation (EMERALD-2).

  Roberts, S.

  17/05/19 → 31/05/23

  Project: Research

• ATLAS-OLE: An Open-label, Long-term Safety and Efficacy Study of Fitusiran in Patients with Hemophilia A or B, with or without Inhibitory Antibodies to Factor VIII or IX.

  Tran, H. & Kennedy, N.

  20/05/19 → 31/12/24

  Project: Research

• A Phase 3, Double-blind, Randomized, Placebo-controlled, Multicenter Study to Determine the Efficacy and Safety of Luspatercept (ACE-536) Versus Placebo in Adults who Require Regular Red Blood Cell Transfusions Due to Beta -Thalassemia

  Kaplan, Z.

  20/05/19 → 19/05/24

  Project: Research

• A phase 1b, multi-arm, open-label, study of HDM201 in combination with MBG453 or venetoclax in adult subjects with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS).

  Wei, A. & Kennedy, N.

  23/05/19 → 23/05/24

  Project: Research

• A phase 2b randomised, double-blind, parallel-group study of alginate oligosaccharide (OligoG) dry powder inhalation in addition to standard of care compared to placebo in addition to standard of care in patients with Cystic Fibrosis (CF).

  Wilson, J.

  23/05/19 → 31/12/20

  Project: Research

• A phase 1a/1b multicenter, open-label, dose escalation, dose expansion study evaluating the safety, pharmacokinetics and activity of GDC-9545 alone or in combination with palbociclib and/or LHRH agonist in patients with locally advanced or metastatic estrogen receptor-positive breast cancer [GO39932].

  Richardson, G. & Baker, E.

  24/05/19 → 31/12/24

  Project: Research

• Minimal genomics lab for AMR surveillance and diagnostics in provincial low-income settings.

  Okeke, I. & Holt, K.

  27/05/19 → 15/04/21

  Project: Research

• A Phase 1 Study of the Safety, Tolerability, Pharmacokinetics, and Food Effect of Single and Multiple Doses of ABI-H2158 in Healthy Volunteers; and the Multiple-Ascending Dose Pharmacokinetics and Pharmacodynamics in Patients with Chronic Hepatitis B Infection.

  Roberts, S. & Mitchell, J. L.

  29/05/19 → 30/09/19

  Project: Research

• A Phase I Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Immunogenicity of Single and Multiple Doses of AL002 in Healthy Participants and in Participants with Mild to Moderate Alzheimer's Disease.

  O'Brien, T. & Brodtmann, A.

  30/05/19 → 31/12/19

  Project: Research

• A Phase 2, Randomized, Double-blind Study to Evaluate the Efficacy and Safety of VX-561 in Subjects Aged 18 Years and Older With Cystic Fibrosis.

  Wilson, J.

  30/05/19 → 29/02/20

  Project: Research

• How to diagnose ataxia

  Szmulewicz, D.

  1/06/19 → 31/12/20

  Project: Research

• Bazedoxifene – A New Selective Estrogen Receptor Modulator Treatment for People with Schizophrenia

  Kulkarni, J., Gurvich, C., Thomas, N., Sundram, S., Hill, R. & Chu, S.

  1/06/19 → 31/05/22

  Project: Research

• Identification and Forecasting of Seizure from EEG data recorded from rodents in Laboratory settings using QA/QC and Machine Learning Algorithms Stage 2

  O'Brien, T., Casillas-Espinosa, P. & Knight, K.

  Monash University – Internal Faculty Contribution

  1/06/19 → 30/05/21

  Project: Research

• A Phase 2 Clinical Trial Evaluating the Efficacy, Safety, Tolerability, and Pharmacokinetics of PRAX-944 in Adults with Essential Tremor

  Thyagarajan, D., Bertram, K., Fung, V. S. C., Adam, R. J., Lehn, A., Evans, A., Kimber, T. E., Lehn, A. & Burn, K.

  1/06/19 → 30/06/20

  Project: Research

• A Phase 2 Clinical Trial of PRAX-114 to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy in Participants with Major Depressive Disorder.

  Kulkarni, J., De Castella, A. & Gurvich, C.

  1/06/19 → 31/12/20

  Project: Research

• Transforming pulmonary rehabilitation to reduce hospital admissions in COPD

  Holland, A., McDonald, C. F., Mahal, A. S., Lannin, N., Cox, N., Hepworth, G. & OʼHalloran, P. D.

  Department of Health (Australia)

  1/06/19 → 31/08/22

  Project: Research

• A Randomized, Double-Blind, Placebo Controlled Study to Investigate the Efficacy and Safety of High Strength Cranberry (Pacran) in Women with Recurrent Urinary Tract Infections (Cystitis).

  Kulkarni, J., De Castella, A. & Sharp, G.

  1/06/19 → 31/12/20

  Project: Research

• Preferences and cost-effectiveness of case detection and management strategies for chlamydia control in Hong Kong

  Ong, J. & Wong, W. C. W.

  1/06/19 → 31/05/21

  Project: Research

• A Prospective, Single-arm, Multicenter Study to Evaluate the Safety and Performance of the Instylla Hydrogel Embolic System (HES) For Patients Requiring Vascular Embolization Alone or in the Pre-operative Setting for Treatment of Malignant and Benign Hypervascular Tumors, and Select Non-Traumatic End-Organ Infarct.

  Goh, G., Clements, W., Koukounaras, J. & Kavnoudias, H.

  3/06/19 → 31/12/24

  Project: Research

• An open-label, multicenter, extension study to evaluate the safety and efficacy of Padsevonil as adjunctive treatment of focal-onset seizures in adult subjects with drug-resistant epilepsy.

  O'Brien, T., Perucca, P., D'Souza, W. J., Berkovic, S. F., Wijayath, M., Carney, P., Seneviratne, U., Reutens, D. C., Zentner, C., Frasca, J. & Nikpour, A.

  4/06/19 → 31/12/21

  Project: Research

• Improved monitoring of Multiple Sclerosis (MS) using patient-derived and MRI scan information.

  Butzkueven, H.

  6/06/19 → 27/02/23

  Project: Research

• A Randomized Open-Label, Phase 1b Study of the Safety of Pirfenidone Solution for Inhalation (AP01) in Patients with Idiopathic Pulmonary Fibrosis (ATLAS Study)

  Glaspole, I. & Symons, K. M.

  7/06/19 → 1/06/22

  Project: Research

• A Phase 3, randomized, double-blind, parallel-group, placebo controlled multicenter study to evaluate the efficacy and safety of two doses of GLPG1690 in addition to local standard of care for minimum 52 weeks in subjects with idiopathic pulmonary fibrosis.

  Glaspole, I. & Symons, K. M.

  7/06/19 → 1/12/22

  Project: Research

• A Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of GS-4224 in Healthy Volunteers and Subjects with the Chronic Hepatitis B (CHB) Virus

  Roberts, S. & Jones, A.

  19/06/19 → 31/05/21

  Project: Research

• A prospective, cross-sectional, multi-centre study to evaluate the clinical performance of the ColoSTAT In Vitro Diagnostic for the detection and evaluation of Biomarkers associated with the occurrence of colorectal cancer.

  Brown, G.

  21/06/19 → 31/07/20

  Project: Research

• An Adaptive, Open-Label, Dose-Finding, Phase 1/2 Study Investigating the Safety, Pharmacokinetics, and Clinical Activity of PRN1008, an Oral BTK Inhibitor, in Patients with Relapsed Immune Thrombocytopenic Purpura

  Kaplan, Z.

  24/06/19 → 23/06/24

  Project: Research

• CLADIN sub study. Effect of CLADribine on Innate Immune Response (CLADIN). MS Immunity Project.

  Monif, M., Butzkueven, H. & O'Brien, T.

  27/06/19 → 9/09/22

  Project: Research

• A Dose Escalation Study to Evaluate the Effect of RT234 on Cardiopulmonary Hemodynamics in Subjects with Pulmonary Arterial Hypertension.

  Kaye, D.

  27/06/19 → 31/12/20

  Project: Research

• Klebsiella pneumoniae – a key driver in the global spread of antimicrobial resistance and a target for new approaches in diagnostics, surveillance and alternative therapeutics (KLEB-GAP).

  Sundsfjord, A., Hoyland Lohr, I., Samuelsen, O., Sunde, M., Lunestad, B. T., Brisse, S., Giske, C., Bengoechea, J., Holt, K. & Frantzen, C.

  30/06/19 → 31/12/23

  Project: Research

• Immediate and Long-term Health and Psychosocial Outcomes Evaluation for “Treatment Gap” in People with Newly Diagnosed Epilepsy in Australia

  Chen, B., Ademi Delaney, Z., Lawn, N. D., Kwan, P., Dunne, J. & Lee, J.

  30/06/19 → 31/12/20

  Project: Research

• Assessing diagnostic accuracy for melanoma with compared to without access to Melanoma Surveillance Photography in high-risk individuals

  Mar, V., Cust, A. E., Soyer, P., Morton, R., Wolfe, R., Guitera, P., White, P., Janda, M., Fishburn, P. & Kelly, J.

  Department of Health (Australia)

  30/06/19 → 29/10/22

  Project: Research

• A Phase 3, Multicenter, randomized, double-blind Study of the Efficacy and Safety of Rezafungin for Injection versus Intravenous Caspofungin Followed by Optional Oral Fluconazole Step-down in the Treatment of Subjects with Candidemia and /or Invasive Candidiasis (The ReSTORE Study).

  Morrissey, O. & Roney, J.

  1/07/19 → 28/02/21

  Project: Research

• Audit of the technical success and early outcomes of Radiologic insertion of Gastrostomy (RIG)

  Clements, W., Shvarts, Y., Kavnoudias, H., Murnane, L., Phan, T., Lee, R. & Zia, A.

  1/07/19 → 31/12/20

  Project: Research

• Active Participatory Health Monitoring in people with Multiple Sclerosis to improve treatment outcomes (Active-MS)

  Butzkueven, H., Van Der Walt, A., Darby, D., Stankovich, J., Jokubaitis, V., Skibina, O., Marriott, M., Butler, E. & Gresle, M.

  Department of Health (Australia)

  1/07/19 → 30/06/21

  Project: Research

• Assessing the significance of Incidental Liver Lesions on Total Body Emergency CT Scans

  Zhang, B., Clements, W., Ratnakanthan, P. & Shekarforoush, M.

  1/07/19 → 31/12/20

  Project: Research

• Tackling superbugs: an integrated antimicrobial resistance infection prevention genomics service

  Peleg, A.

  1/07/19 → 30/06/21

  Project: Research

• Be Your Best: an innovative, co-designed approach to frailty and care transitions from hospital to home, in people aged 65 years or more.

  Lowthian, J., Mills, A., Cyarto, L., Meyer, C., Dickins, M., Thurgood, L., Boyd, L., Walker, K., Rose, M., De Villiers Smit, P., Newnham, H. & Hutchinson, A. M.

  Department of Health (Australia)

  1/07/19 → 30/06/21

  Project: Research

• The Damian Project

  Kulkarni, J., Gurvich, C., De Castella, A. & Thomas, N.

  The Mohr Family

  1/07/19 → 30/06/28

  Project: Research

• Long term immune function and complication rates after splenic artery emboli zation for blunt abdominal trauma

  Clements, W., Lukies, M. W., Kavnoudias, H., Joseph, T. & Bosco, J. J.

  1/07/19 → 31/12/20

  Project: Research

• Using smart technology to more effectively and efficiently monitor the quality of cancer care

  Zalcberg, J., Evans, S., Bain, C., Aleti, A., Mac Manus, C., Brown, W., Sievert, W., Evans, P., Davis, I., Evans, M., Holland, J. & Brand, M.

  Department of Health (Australia)

  1/07/19 → 30/06/21

  Project: Research

• Preventing suicide in perimenopausal women: Disseminating our new approach

  Kulkarni, J., De Castella, A. & Gurvich, C.

  1/07/19 → 30/06/20

  Project: Research

• Conducting efficacy and implementation trials to improve the evidence-base of stroke rehabilitation to improve participation outcomes

  Lannin, N.

  1/07/19 → 31/12/22

  Project: Research