Central Clinical School

Projects

Projects per year 2000 2028

• 15 Curtailed
• 28 Not started
• 533 Active
• 1148 Finished

Projects per year

Search results

• The Damian Project

  Kulkarni, J., Gurvich, C., De Castella, A. & Thomas, N.

  The Mohr Family

  1/07/19 → 30/06/28

  Project: Research

• Monash-Roche Meaningful Data at Scale Collaboration for MS

  Van Der Walt, A. & Butzkueven, H.

  Hoffmann-La Roche Switzerland

  6/12/19 → 31/12/27

  Project: Research

• A Phase Ib/II Study, Evaluating the Safety and Efficacy of Idasanutlin in Combination with Cytarabine and Daunorubicin in Patients Newly Diagnosed with Acute Myeloid Leukemia (AML) and the Safety and Efficacy of Idasanutlin in the Maintenance of First AML Complete Remission.

  Wei, A. & Kennedy, N.

  17/07/19 → 31/12/26

  Project: Research

• A Study to Evaluate the Feasibility and Safety of the Millipede Transcatheter Annuloplasty Ring System in Patients with Functional Mitral Regurgitation (Millipede Feasibility Study).

  Walton, T. & Holland, S.

  29/07/20 → 31/12/26

  Project: Research

• Collaboration on Roche Managed Primary Data Collection NIS and RWD Analytics Activities

  Butzkueven, H. & Van Der Walt, A.

  Hoffmann-La Roche Switzerland

  6/12/19 → 1/12/26

  Project: Research

• Quantifying myocardial inflammation in acute rheumatic fever and rheumatic heart disease

  O'Brien, J. & Taylor, A.

  23/03/20 → 22/03/26

  Project: Research

• ARC Research Hub to Combat Antimicrobial Resistance

  Guy, R. J., Broom, A., Whiley, D., Bradshaw, C., Applegate, T., Treloar, C., Wiseman, V., Huston, W., Williamson, D. A., Kaldor, J., Vallely, A., Hocking, J. S., Regan, D. G., Donovan, B., Kelly-Hanku, A. M., Mokany, E., Todd, A. V., Persing, D., Tenover, F., Graham, J., Phillips, J., Boulos, R., Field, P., Thistlethwaite, J., Chomley, P., Fairley, C., Lewis, D. A., McNulty, A., Lahra, M. M., Murray, G. L., Pomat, W. S. & Phanuphak, N.

  16/02/21 → 16/02/26

  Project: Research

• The Meydan Family Foundation Diabetes Complications Research Hub

  Cooper, M., Jane, S. & Mitchell, C.

  31/12/16 → 31/12/25

  Project: Research

• An Open-Label, Phase 2a/2b Study of KRT-232 in Subjects With Primary Myelofibrosis (PMF), Post–Polycythemia Vera MF (Post-PV-MF), Or Post–Essential Thrombocythemia MF(Post–ET-MF) Who Have Failed Prior Treatment with a JAK Inhibitor (KRT-232-101)

  Perkins, A. & Kennedy, N.

  20/01/20 → 31/12/25

  Project: Research

• A Phase I/II, Open-Label, Multicentre 2-Part Study to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of AZD2811 as Monotherapy or in Combination in Treatment-Naïve or Relapsed/Refractory Acute Myeloid Leukaemia Patients Not Eligible for Intensive Induction Therapy.

  Wei, A. & Kennedy, N.

  6/10/20 → 31/12/25

  Project: Research

• An Open-Label, Multi-Center, Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7283420 as a Single Agent in Hematologic and Molecular Relapsed/Refractory Acute Myeloid Leukaemia.

  Wei, A., Bajel, A. & Kennedy, N.

  20/10/20 → 31/12/25

  Project: Research

• A Phase 2 Open-Label Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination with Ruxolitinib in Subjects with Myelofibrosis

  Perkins, A.

  6/03/20 → 31/12/25

  Project: Research

• Efficacy and Safety of Concizumab prophylaxis in patients with haemophilia A or B without inhibitors (Explorer8)

  Tran, H. & Kennedy, N.

  20/01/20 → 31/12/25

  Project: Research

• ENZA-p: A randomised phase II trial using PSMA as a therapeutic agent and prognostic indicator in men with metastatic castration-resistant prostate cancer treated with enzalutamide.

  Voskoboynik, M. & Hawkins, C.

  22/09/20 → 31/12/25

  Project: Research

• An open-label, multi-center, long-term extension study of Zanubrutinib (BGB-3111) in patients with B-cell malignancies

  Kenealy, M. & Baker, E.

  13/02/20 → 31/12/25

  Project: Research

• A Phase 3, Randomized, Double-Blind Study of Adjuvant Immunotherapy with Nivolumab versus Placebo after Complete Resection of Stage IIB/C Melanoma.

  Haydon, A. & Hawkins, C.

  12/02/20 → 31/12/25

  Project: Research

• A 46-week, Double-blind, Placebo-controlled, Phase 3 Study with a 6-week Randomized-withdrawal Period to Evaluate the Safety and Efficacy of Relamorelin in Patients with Diabetic Gastroparesis.

  Burgell, R. & McKenzie, J.

  26/03/20 → 31/12/25

  Project: Research

• Gene-transfer, open-label, dose escalation study of SPK-8011 [adeno-associated viral vector with B-domain-deleted human factor VIII gene] in individuals with haemophilia A

  Tran, H. & Kennedy, N.

  14/02/20 → 31/12/25

  Project: Research

• Screening/Observational Protocol to Determine Patient Eligibility for Inclusion in AAV Gene Therapy Clinical Trials (ECLIPSE)

  Tran, H. & Kennedy, N.

  20/02/20 → 31/12/25

  Project: Research

• A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Clinical Outcomes, Antiviral Activity, Safety, Tolerability, Pharmacokinetics, and Pharmacokinetics/Pharmacodynamics of JNJ-53718678 in Adult and Adolescent Hematopoietic Stem Cell Transplant Recipients with Respiratory Syncytial Virus Infection of the Upper Respiratory Tract (FREESIA)

  Kliman, D., Kennedy, N. & Thompson, K.

  15/01/20 → 31/12/25

  Project: Research

• A Phase 3b, Single Arm, Open-label Study to Evaluate the Efficacy and Safety of BMN 270, an Adeno-Associated Virus Vector-Mediated Gene Transfer of Human Factor VIII, with Prophylactic Corticosteroids in Hemophilia A Patients.

  Tran, H. & Kennedy, N.

  2/12/20 → 31/12/25

  Project: Research

• An open-label extension of Study M15-741 to evaluate the safety and tolerability of 24-hour daily exposure of continuous subcutaneous infusion of ABBV-951 in subjects with Parkinson's disease.

  Bertram, K., Fung, V. S. C., Hayes, M., Stell, R., Kimber, T. E. & Bonke, V.

  6/10/20 → 31/12/25

  Project: Research

• Efficacy and Safety of Concizumab prophylaxis in patients with haemophilia A or B with inhibitors (Explorer7).

  Tran, H. & Kennedy, N.

  20/01/20 → 31/12/25

  Project: Research

• A Phase 3, multicenter, open-label, randomized study to evaluate the efficacy and safety of Fedratinib compared to best available therapy in subjects with DIPSS-Intermediate or High-Risk Primary Myelofibrosis, Post-Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis and previously treated with ruxolitinib (The FREEDOM 2 trial)

  Perkins, A. & Kennedy, N.

  16/12/19 → 31/12/25

  Project: Research

• A Multicenter, Open-Label, Randomized Phase III Study to Evaluate the Efficacy and Safety of the Combination of Belantamab Mafodotin, Bortezomib, and Dexamethasone (B-Vd) Compared with the Combination of Daratumumab, Bortezomib and Dexamethasone (D-Vd) in Participants with Relapsed/Refractory Multiple Myeloma – DREAMM 7.

  Spencer, A. & Kennedy, N.

  22/09/20 → 31/12/25

  Project: Research

• A Phase III, Open Label, Randomized Study to Evaluate the Efficacy and Safety of Single Agent Belantamab Mafodotin Compared to Pomalidomide plus Lowdose Dexamethasone (pom/dex) in Participants with Relapsed/Refractory Multiple Myeloma (RRMM) (DREAMM 3).

  Spencer, A. & Kennedy, N.

  17/09/20 → 31/12/25

  Project: Research

• Leaving no one behind: community-driven approaches to eliminate HIV in Australia

  Ong, J.

  1/01/21 → 31/12/25

  Project: Research

• Phase I/II, international, multicentre, open-label, non-randomised, non-comparative, study evaluating the safety, tolerability and clinical activity of intravenously administered S64315, a selective Mcl-1 inhibitor, in combination with azacitidine in patients with acute myeloid leukaemia (AML).

  Wei, A. & Kennedy, N.

  6/10/20 → 31/12/25

  Project: Research

• A Phase 1b/III study of Ipatasertib plus Palbociclib and Fulvestrant versus placebo plus Palbociclib and Fulvestrant in hormone receptor positive and Her2 negative locally advanced unresectable or metastatic breast cancer [Ipatunity150] [CO41012]

  Antill, Y., Baker, E. & Thompson, K.

  13/02/20 → 31/12/25

  Project: Research

• A Phase 1b, Multi-center, Randomized, Double blind, Placebo-controlled Study to Investigate the Efficacy, Safety and Pharmacokinetics of CSL312 in the Prevention of Peripherally Inserted Central Catheter (PICC)-associated Thrombosis in Subjects with Cancer

  Tran, H., Chunilal, S., Casey, J., Sanmugarajah, J. & Kennedy, N.

  10/02/20 → 31/12/25

  Project: Research

• A Phase 1 Study of Oral LY3410738 in Patients with Advanced Hematologic Malignancies with IDH1 or IDH2 Mutations.

  Wei, A. & Kennedy, N.

  2/12/20 → 31/12/25

  Project: Research

• An Open-Label Study in Adolescent and Adult Severe (Coagulation Factor Activity <1%) Hemophilia A or B Patients With or Without Inhibitors Comparing Standard Treatment to PF-06741086 Prophylaxis.

  Tran, H. & Kennedy, N.

  6/10/20 → 31/12/25

  Project: Research

• A Randomized, Double-Blind, Phase 3 Study to Evaluate the Activity of Momelotinib (MMB) versus Danazol (DAN) in Symptomatic, Anemic Subjects with Primary Myelofibrosis (PMF), Post-Polycythemia Vera (PV) Myelofibrosis, or Post Essential Thrombocythemia (ET) Myelofibrosis who were Previously Treated with JAK Inhibitor Therapy

  Perkins, A., Leahy, M. F., Ross, D., Prasad, R. & Kennedy, N.

  5/02/20 → 31/12/25

  Project: Research

• A Two-Part, Randomized, Open-label, Multicenter, Phase 2a/2b Study of the Efficacy, Safety, and Pharmacokinetics of KRT-232 Compared to Ruxolitinib in Patients with Phlebotomy-Dependent Polycythemia Vera (KRT-232-102)

  Perkins, A., Burbury, K. L. & Kennedy, N.

  20/01/20 → 31/12/25

  Project: Research

• CARTITUDE-4: A Phase 3 Randomized Study Comparing JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA, versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd) in Subjects with Relapsed and Lenalidomide-Refractory Multiple Myeloma

  Spencer, A. & Kennedy, N.

  18/03/20 → 31/12/25

  Project: Research

• Multi-dimensional monitoring of cognition and cerebellar function to prospectively define disease progression in multiple sclerosis

  Van Der Walt, A.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/21 → 31/12/25

  Project: Research

• ENHANCE: A Randomized, Double-blind, Multicenter Study Comparing Magrolimab in Combination with Azacitidine versus Azacitidine Plus Placebo in Treatment-naïve Patients with Higher Risk Myelodysplastic Syndrome.

  Wei, A., Kennedy, N., Fong, C. Y., Kenealy, M., D'Rozario, J., Forsyth, C. J., Shortt, J., Hertzberg, M. S., Bajel, A. & Kwan, J.

  1/09/20 → 31/12/25

  Project: Research

• Optimising patient & health system outcomes in chronic respiratory disease

  Holland, A.

  1/01/21 → 31/12/25

  Project: Research

• Brain stimulation therapeutics for mental health disorders: from concept to clinical application

  Fitzgerald, P.

  1/01/21 → 31/12/25

  Project: Research

• The role of a low emulsifier diet to treat Crohn's disease

  Halmos, E.

  1/01/21 → 31/12/25

  Project: Research

• A Phase 1, Open-label, Multiple-Ascending Dose Study of the Safety and Tolerability of T3011 in Advanced Cutaneous or Subcutaneous Malignancies

  Haydon, A. & Hawkins, C.

  20/01/20 → 31/12/25

  Project: Research

• A Phase 3 Open Label Extension Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia (C-935788-058).

  Tran, H. & Kennedy, N.

  31/03/20 → 31/12/25

  Project: Research

• A Randomized, Open-Label, Phase 3 Study Evaluating Efficacy and Safety of Navitoclax in Combination with Ruxolitinib Versus Best Available Therapy in Subjects with Relapsed/Refractory Myelofibrosis (TRANSFORM-2).

  Perkins, A., Kennedy, N., Hamad, N. & Chuah, H.

  12/10/20 → 31/12/25

  Project: Research

• CERPASS: A Randomized, Controlled, Open-Label, Phase 2 Study of Cemiplimab as a Single Agent and in Combination with RP1 in Patients with Advanced Cutaneous Squamous Cell Carcinoma.

  Haydon, A. & Hawkins, C.

  12/12/19 → 31/12/25

  Project: Research

• A Phase 3, Randomized, Double-blind, Controlled Study Evaluating the Efficacy and Safety of VX-445 Combination Therapy in Subjects with Cystic Fibrosis Who Are Heterozygous for the F508del Mutation and a Gating or Residual Function Mutation (F/G and F/RF Genotypes).

  Keating, D.

  21/10/19 → 31/12/25

  Project: Research

• Revolutionising Multiple Sclerosis Care and trials through e-health

  Butzkueven, H.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/21 → 31/12/25

  Project: Research

• A Phase 4, Open-Label, Randomized Study of Two Inotuzumab Ozogamicin Dose Levels in Adult Patients With Relapsed or Refractory B-Cell Acute Lymphoblastic leukemia Eligible for Hematopoietic Stem Cell Transplantation and Who Have Risk Factor(s) for Veno-Occlusive Disease.

  Fleming, S. A. & Kennedy, N.

  9/07/19 → 31/12/25

  Project: Research

• COVIDIAB Registry - Collecting data of COVID-19 complications in relations to Diabetes

  Zimmet, P.

  1/09/20 → 30/09/25

  Project: Research

• Developing Treatments for Vitiligo and Melanoma

  Shackleton, M.

  1/07/20 → 30/06/25

  Project: Research

• Developing Treatments for Vitiligo and Melanoma

  Shackleton, M.

  Vitiligo Association of Australia

  1/07/20 → 30/06/25

  Project: Research