Central Clinical School

Projects

Projects per year

2000 2028

• 15 Curtailed
• 26 Not started
• 520 Active
• 1141 Finished

Projects per year

Search results

• A Randomized, Double-blind, Placebo Controlled Phase 3 Study of Venetoclax in Combination with Azacitidine Versus Azacitidine in Treatment Naive Subjects with Acute Myeloid Leukemia who are ineligible for Standard Induction Therapy.

  Wei, A. & Kennedy, N.

  27/11/17 → 2/11/22

  Project: Research

• Prospective clinic and home-based serial monitoring of cognition in relapsing-remitting multiple sclerosis.

  Van Der Walt, A. & Butzkueven, H.

  13/09/18 → 13/11/22

  Project: Research

• A Randomized, Double-Blind, Double-Dummy, Active-Controlled Study Comparing the Efficacy, Safety and Tolerability of ABBV-951 to Oral Carbidopa/Levodopa in Advanced Parkinson's Disease Patients.

  Bertram, K. & Burn, K.

  1/11/20 → 30/11/22

  Project: Research

• MS Reactor - Prospective clinic and home-based monitoring of cognition in relapsing remitting multiple sclerosis.

  Van Der Walt, A.

  17/12/18 → 30/11/22

  Project: Research

• MS Reactor - Prospective clinic and home-based monitoring of cognition in relapsing remitting multiple sclerosis.

  Van Der Walt, A. & Lechner-Scott, J.

  5/10/18 → 30/11/22

  Project: Research

• MS Reactor - Prospective clinic and home-based monitoring of cognition in relapsing remitting multiple sclerosis.

  Van Der Walt, A.

  4/10/18 → 30/11/22

  Project: Research

• A Phase 3, randomized, double-blind, parallel-group, placebo controlled multicenter study to evaluate the efficacy and safety of two doses of GLPG1690 in addition to local standard of care for minimum 52 weeks in subjects with idiopathic pulmonary fibrosis.

  Glaspole, I. & Symons, K. M.

  7/06/19 → 1/12/22

  Project: Research

• Investigating the genetic contribution to the focal epilepsies

  Perucca, P.

  1/01/19 → 1/01/21

  Project: Research

• Improving the Impact of Perioperative Clinical Trials

  Myles, P.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/18 → 31/12/22

  Project: Research

• Precision medicine for epilepsy and beyond: from discovery to implementation and evaluation

  Kwan, P.

  1/01/18 → 31/12/22

  Project: Research

• Brain Ageing - studying causes and developing interventions

  Srikanth, V.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/18 → 31/12/22

  Project: Research

• FODMAP: Changing therapeutic paradigms for intestinal health: Diet as a therapeutic strategy in Gastroenterology.

  Muir, J.

  1/01/18 → 31/12/22

  Project: Research

• Curing blood cancers: rapid translation from target to drug to clinic

  Curtis, D.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/18 → 31/12/22

  Project: Research

• Type 2 immunity: a regulator of physiology, tissue repair and metabolism

  Harris, N.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/18 → 31/12/22

  Project: Research

• Understanding how group 2 innate lymphoid cells in early life regulate postnatal lung development and susceptibility to chronic respiratory diseases

  Starkey, M.

  1/07/20 → 31/12/22

  Project: Research

• Genomic Investigations of Antimicrobial Resistance

  Holt, K.

  Equity Trustees

  1/01/19 → 31/12/22

  Project: Other

• A randomised, double-blind, placebo-controlled parallel group study in IPF patients over 12 weeks evaluating efficacy, safety and tolerability of BI 1015550 taken orally.

  Glaspole, I. & Symons, K. M.

  15/09/20 → 31/12/22

  Project: Research

• MIDAS 2. A Phase III, Multicentre, Prospective, Randomised, Placebo-controlled, Double-blind, Parallel group, with an adaptive sample size re-estimation study in Stroke Survivors.

  Cloud, G. & Moore, A.

  1/02/19 → 31/12/22

  Project: Research

• A Phase 3, Randomized, Double-Blind, Placebo-Controlled Efficacy and Safety Study of Pamrevlumab in Subjects with Idiopathic Pulmonary Fibrosis (IPF)

  Glaspole, I. & Symons, K. M.

  23/06/20 → 31/12/22

  Project: Research

• A Phase 3 Randomized, Active-Controlled, Open-Label Clinical Study to Evaluate a Switch to Doravirine/Islatravir (DOR/ISL) Once-Daily in Participants with HIV-1 Virologically Suppressed on Antiretroviral Therapy

  Schmidt, T. & Silvers, J.

  5/06/20 → 31/12/22

  Project: Research

• Antidepressants in epilepsy

  Jones, N. & Pitkanen, A.

  1/01/19 → 31/12/22

  Project: Research

• Bespoke nanomaterials for understanding nano-bio interactions under flow

  Davis, T., Truong Phuoc, N., Kent, S. & Anastasaki, A.

  1/01/20 → 31/12/22

  Project: Research

• An open label phase Ib dose finding study of BI 836880 in combination with BI 754091 to characterize safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy in patients with locally advanced or metastatic non-squamous Non-Small Cell Lung Cancer and in other solid tumors.

  Voskoboynik, M., Richardson, G. E. & Hawkins, C.

  1/07/20 → 31/12/22

  Project: Research

• Effectiveness of Occupational Therapy Homevisits to Improve Participation after Stroke

  Lannin, N., Cadilhac, D., Clemson, L. M., Drummond, A., Cameron, I., Crotty, M., Usherwood, T., Andrew, N., Laver, K. E. & Stanley, M.

  1/01/18 → 31/12/22

  Project: Research

• An Open-Label, Multicenter, Phase I/Ib Trial Evaluating the Safety, Efficacy, and Pharmacokinetics of Escalating Doses of mosunetuzumab (BTCT4465A) as a Single Agent and Combined with Atezolizumab in Patients with Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma and Chronic Lymphocytic Leukemia

  Fleming, S. A., Patil, S. & Kennedy, N.

  6/03/19 → 31/12/22

  Project: Research

• MSPP: Multiple Sclerosis: Pregnancy and Prognosis

  Jokubaitis, V., Van Der Walt, A., Hellwig, K., McCombe, P. & Stankovich, J.

  1/01/19 → 31/12/22

  Project: Research

• Conducting efficacy and implementation trials to improve the evidence-base of stroke rehabilitation to improve participation outcomes

  Lannin, N.

  1/07/19 → 31/12/22

  Project: Research

• A Phase 2, Randomized Clinical Study of Intravenous or Intratumoral Administration of V937 in Combination with Pembrolizumab (MK-3475) Versus Pembrolizumab Alone in Participants with Advanced/Metastatic Melanoma

  Haydon, A., Hawkins, C. & Khattak, A.

  12/12/19 → 31/12/22

  Project: Research

• Augmenting the activity of glyoxalase-1 to increase dicarbonyl clearance

  Thomas, M.

  1/01/20 → 31/12/22

  Project: Research

• Mechanisms of AML differentiation therapy response and relapse

  Dickins, R.

  1/01/20 → 31/12/22

  Project: Research

• Free fatty acid receptors as novel bronchodilator targets in severe asthma

  Bourke, J., Dubsky, S., Royce, S., Westall, G., Grainge, C., Oliver, B. G., Ulven, T. & Bardin, P.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/20 → 31/12/22

  Project: Research

• Exploiting Biased Agonists of Formyl Peptide Receptors as Pharmacotherapy for Pulmonary Hypertension: simultaneous targeting of vascular function and remodelling

  Qin, C. H., Jackson, K. L. & Woodman, O. L.

  1/04/20 → 31/12/22

  Project: Research

• Prevention of post-stroke epilepsy in patients with acute ischaemic stroke at high risk of developing seizures.

  Kwan, P., O'Brien, T., Yan, B., Nicolo, J., Cloud, G., Moffat, B. A., Wright, D. & Neal, A.

  25/01/19 → 31/12/22

  Project: Research

• Stepped-wedge Trial to increase antibiotic Appropriateness in Residential aged care facilities and model Transmission of antimicrobial Resistance (The START Research Program)

  Peleg, A., Haines, T., Cheng, A., Peel, T., Holt, K. E., Hilmer, S. N., Yun-Hee, J., Stewardson, A. & Spelman, T.

  Department of Health (Australia)

  1/01/18 → 31/12/22

  Project: Research

• Transforming the treatment landscape in elderly Acute Myeloid Leukaemia (AML)

  Wei, A., Bohlander, S. K., Reynolds, J. & Levis, M.

  1/05/19 → 31/12/22

  Project: Research

• An Open Label, Multi-Center, Dose Escalation/Expansion, Phase 1 Study of IMU- 201 (PD1-Vaxx), a B-Cell Immunotherapy, in Adults with Non-Small Cell Lung Cancer [IMU201-101].

  Richardson, G. & Baker, E.

  14/10/20 → 31/12/22

  Project: Research

• A Phase 1b Study of ZN-c3 in Combination with Chemotherapy in Patients with Platinum-Resistant Ovarian, Peritoneal or Fallopian Tube Cancer.

  Richardson, G. & Baker, E.

  22/10/20 → 31/12/22

  Project: Research

• A phase 1, open label, multi-center, dose escalation clinical study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of CN1 in patients with advanced solid tumors or B-cell lymphoma [CN1-101].

  Richardson, G. & Baker, E.

  27/08/20 → 31/12/22

  Project: Research

• AVERT-DOSE (Determining Optimal early rehabilitation after stroke): A multi arm covariate-adjusted, response-adaptive randomised controlled trial.

  Bernhardt, J., Donnan, G., Churilov, L., Langhorne, P., Pandian, J. D., Dewey, H., Srikanth, V., English, C., Moodie, M. & Middleton, S.

  1/01/18 → 31/12/22

  Project: Research

• Active self-monitoring to prospectively detect treatment failure and define subclinical progression trajectories in multiple sclerosis: The ACTIVE-MS Program.

  Van Der Walt, A., Butzkueven, H., Jokubaitis, V., Kolbe, S., Vogel, A. P., Stankovich, J., Butler, E., Macdonell, R. A. L. & Darby, D.

  Trish Multiple Sclerosis Research Foundation

  1/01/20 → 31/12/22

  Project: Research

• Improvement First Seizure Assessment and Management

  O'Brien, T., Perucca, P., Liew, D., Ademi Delaney, Z. & Carney, P.

  Monash University – Internal University Contribution, Epilepsy Foundation

  1/12/20 → 31/12/22

  Project: Research

• Improving the safety and predictable efficacy of thrombolytic therapy in acute ischaemic stroke

  Medcalf, R., Boyd, B. & Cloud, G.

  1/01/19 → 31/12/22

  Project: Research

• A Double-Blind, Randomized, Placebo-Controlled, Safety and Efficacy Study of ANAVEX2-73 in patients with Rett Syndrome.

  O'Brien, T.

  5/04/19 → 31/12/22

  Project: Research

• Validation of new druggable JAK-STAT targets in myeloproliferative neoplasms

  Perkins, A.

  1/01/20 → 31/12/22

  Project: Research

• Targeting Nox5 to prevent atherosclerosis and aneurysm formation

  Jandeleit-Dahm, K. & Touyz, R. M.

  1/01/19 → 31/12/22

  Project: Research

• A Double-Blind, Randomised, Placebo-Controlled, Phase II Study of the Efficacy and Safety of LAU-7B in the Treatment of Cystic Fibrosis in Adults.

  Kotsimbos, T. & deSilva, C.

  16/09/20 → 31/12/22

  Project: Research

• Tailored intervention for reducing falls after stroke trial (FAST)

  Clemson, L., Dean, C. M., Ada, L., Scrivener, K. & Lannin, N.

  1/01/19 → 31/12/22

  Project: Research

• A Phase 3, randomised, double-blind study of adjuvant immunotherapy with Nivolumab versus placebo after complete resection of stage IIB/C Melanoma (CheckMate 76K: CHECKpoint pathway and nivoluMab clinical Trial Evaluation 76K).

  Brady, B. & Baker, E.

  1/04/20 → 31/12/22

  Project: Research

• The Aortix CRS Pilot Study: An Evaluation of the Safety and Performance of the Aortix System for Intra-Aortic Mechanical Circulatory Support in Patients with Cardiorenal Syndrome.

  Walton, T., Stokes, M. B., McKenzie, S. & Holland, S.

  31/01/20 → 31/12/22

  Project: Research

• Establishment of the White Fielding Lab in Neuro-Ophthalmology

  Fielding, J. & White, O.

  1/01/18 → 31/12/22

  Project: Research