Research Output 2016 2019

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2019

AT1R-AT2R-RXFP1 functional crosstalk in myofibroblasts: Impact on the therapeutic targeting of renal and cardiac fibrosis

Chow, B. S. M., Kocan, M., Shen, M., Wang, Y., Han, L., Chew, J. Y., Wang, C., Bosnyak, S., Mirabito-Colafella, K. M., Barsha, G., Wigg, B., Johnstone, E. K. M., Hossain, M. A., Pfleger, K. D. G., Denton, K. M., Widdop, R. E., Summers, R. J., Bathgate, R. A. D., Hewitson, T. D. & Samuel, C. S., Sep 2019, (Accepted/In press) In : Journal of the American Society of Nephrology. 30, 9, 18 p.

Research output: Contribution to journalArticleResearchpeer-review

Atypical cannabinoid ligands O-1602 and O-1918 administered chronically in diet-induced obesity

Simcocks, A. C., Jenkin, K. A., O’Keefe, L., Samuel, C. S., Mathai, M. L., McAinch, A. J. & Hryciw, D. H., Mar 2019, In : Endocrine Connections. 8, 3, p. 203-216 14 p.

Research output: Contribution to journalArticleResearchpeer-review

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Chronic low alcohol intake during pregnancy programs sex-specific cardiovascular deficits in rats

Walton, S. L., Tjongue, M., Tare, M., Kwok, E., Probyn, M., Parkington, H. C., Bertram, J. F., Moritz, K. M. & Denton, K. M., 22 Apr 2019, In : Biology of Sex Differences. 10, 1, 14 p., 21.

Research output: Contribution to journalArticleResearchpeer-review

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Detection of cellular hypoxia by pimonidazole adduct immunohistochemistry in kidney disease: methodological pitfalls and their solution

Ow, C. P. C., Ullah, M. M., Ngo, J. P., Sayakkarage, A. & Evans, R. G., 1 Aug 2019, In : American Journal of Physiology - Renal Physiology. 317, 2, p. F322-F332 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Effect of Furosemide on Urinary Oxygenation in Patients with Septic Shock

Osawa, E. A., Cutuli, S. L., Bitker, L., Canet, E., Cioccari, L., Iguchi, N., Lankadeva, Y. R., Eastwood, G. M., Evans, R. G., May, C. N. & Bellomo, R., 23 Jul 2019, (Accepted/In press) In : Blood Purification. 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Effects of Fluid Bolus Therapy on Renal Perfusion, Oxygenation, and Function in Early Experimental Septic Kidney Injury

Lankadeva, Y. R., Kosaka, J., Iguchi, N., Evans, R. G., Booth, L. C., Bellomo, R. & May, C. N., 1 Jan 2019, In : Critical Care Medicine. 47, 1, p. e36-e43 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Furosemide reverses medullary tissue hypoxia in ovine septic acute kidney injury

Iguchi, N., Lankadeva, Y. R., Mori, T. A., Osawa, E. A., Cutuli, S. L., Evans, R. G., Bellomo, R. & May, C. N., 1 Aug 2019, In : American journal of physiology. Regulatory, integrative and comparative physiology. 317, 2, p. R232-R239 8 p.

Research output: Contribution to journalArticleResearchpeer-review

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Human amnion epithelial cells and their soluble factors reduce liver fibrosis in murine non-alcoholic steatohepatitis

Kuk, N., Hodge, A., Sun, Y., Correia, J., Alhomrani, M., Samuel, C., Moore, G., Lim, R. & Sievert, W., Aug 2019, In : Journal of Gastroenterology and Hepatology (Australia). 34, 8, p. 1441-1449 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Placental effects and transfer of sildenafil in healthy and preeclamptic conditions

Hitzerd, E., Broekhuizen, M., Mirabito Colafella, K. M., Glisic, M., de Vries, R., Koch, B. C. P., de Raaf, M. A., Merkus, D., Schoenmakers, S., Reiss, I. K. M., Danser, A. H. J. & Simons, S. H. P., 1 Jul 2019, In : EBioMedicine. 45, p. 447-455 9 p.

Research output: Contribution to journalArticleResearchpeer-review

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Renal perfusion, oxygenation, and sympathetic nerve activity during volatile or intravenous general anaesthesia in sheep

Iguchi, N., Kosaka, J., Booth, L. C., Iguchi, Y., Evans, R. G., Bellomo, R., May, C. N. & Lankadeva, Y. R., 1 Mar 2019, In : British Journal of Anaesthesia. 122, 3, p. 342-349 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Sepsis-induced acute kidney injury: A disease of the microcirculation

Ma, S., Evans, R. G., Iguchi, N., Tare, M., Parkington, H. C., Bellomo, R., May, C. N. & Lankadeva, Y. R., Feb 2019, In : Microcirculation. 26, 2, 10 p., e12483.

Research output: Contribution to journalArticleResearchpeer-review

Serelaxin enhances the therapeutic effects of human amnion epithelial cell-derived exosomes in experimental models of lung disease

Royce, S. G., Patel, K. P., Mao, W., Zhu, D., Lim, R. & Samuel, C. S., Jul 2019, In : British Journal of Pharmacology. 176, 13, p. 2195-2208 14 p.

Research output: Contribution to journalArticleResearchpeer-review

Strategies that improve renal medullary oxygenation during experimental cardiopulmonary bypass may mitigate postoperative acute kidney injury

Lankadeva, Y. R., Cochrane, A. D., Marino, B., Iguchi, N., Hood, S. G., Bellomo, R., May, C. N. & Evans, R. G., Jun 2019, In : Kidney International. 95, 6, p. 1338-1346 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Strong and Sustained Antihypertensive Effect of Small Interfering RNA Targeting Liver Angiotensinogen

Uijl, E., Mirabito Colafella, K. M., Sun, Y., Ren, L., van Veghel, R., Garrelds, I. M., de Vries, R., Poglitsch, M., Zlatev, I., Kim, J. B., Hoorn, E. J., Foster, D. & Danser, A. H. J., 1 Jun 2019, In : Hypertension. 73, 6, p. 1249-1257 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation

Singh, R. R., McArdle, Z. M., Iudica, M., Easton, L. K., Booth, L. C., May, C. N., Parkington, H. C., Lombardo, P., Head, G. A., Lambert, G., Moritz, K. M., Schlaich, M. P. & Denton, K. M., 1 Mar 2019, In : Hypertension. 73, 3, p. 718-727 10 p.

Research output: Contribution to journalArticleResearchpeer-review

Synchronised nesting aggregations are associated with enhanced capacity for extended embryonic arrest in olive ridley sea turtles

Williamson, S. A., Evans, R. G., Robinson, N. J. & Reina, R. D., 5 Jul 2019, In : Scientific Reports. 9, 1, 8 p., 9783.

Research output: Contribution to journalArticleResearchpeer-review

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2018

Absence of renal hypoxia in the subacute phase of severe renal ischemia-reperfusion injury

Ow, C. P. C., Ngo, J. P., Ullah, M. M., Barsha, G., Meex, R. C., Watt, M. J., Hilliard, L. M., Koeners, M. P. & Evans, R. G., Nov 2018, In : American Journal of Physiology - Renal Physiology. 315, 5, p. F1358-F1369 12 p.

Research output: Contribution to journalArticleResearchpeer-review

Alterations in regional kidney oxygenation during expansion of extracellular fluid volume in conscious healthy sheep

Lankadeva, Y. R., Evans, R. G., Kosaka, J., Booth, L. C., Iguchi, N., Bellomo, R. & May, C. N., 1 Dec 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 315, 6, p. R1242-R1250 9 p.

Research output: Contribution to journalArticleResearchpeer-review

A model of oxygen transport in the rat renal medulla

Lee, C. J., Gardiner, B. S., Evans, R. G. & Smith, D. W., 1 Dec 2018, In : American Journal of Physiology - Renal Physiology. 315, 6, p. F1787-F1811 25 p.

Research output: Contribution to journalArticleResearchpeer-review

APOL1 Risk Variants Independently Associated With Early Cardiovascular Disease Death

Hughson, M. D., Hoy, W. E., Mott, S. A., Bertram, J. F., Winkler, C. A. & Kopp, J. B., 1 Jan 2018, In : Kidney International Reports. 3, 1, p. 89-98 10 p.

Research output: Contribution to journalArticleResearchpeer-review

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Diet-induced vitamin D deficiency has no effect on acute post-stroke outcomes in young male mice

Evans, M. A., Kim, H. A., De Silva, T. M., Arumugam, T. V., Clarkson, A. N., Drummond, G. R., Zosky, G. R., Broughton, B. R. S. & Sobey, C. G., 1 Nov 2018, In : Journal of Cerebral Blood Flow and Metabolism. 38, 11, p. 1968-1978 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Hexarelin treatment preserves myocardial function and reduces cardiac fibrosis in mouse model of acute myocardial infarction

McDonald, H., Peart, J., Kurniawan, N., Galloway, G., Royce, S., Samuel, C. S. & Chen, C., 13 May 2018, In : Physiological Reports. 6, 9, 14 p., e13699.

Research output: Contribution to journalArticleResearchpeer-review

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IL-33 modulates inflammatory brain injury but exacerbates systemic immunosuppression following ischemic stroke

Zhang, S. R., Piepke, M., Chu, H. X., Broughton, B. R. S., Shim, R., Wong, C. H. Y., Lee, S., Evans, M. A., Vinh, A., Sakkal, S., Arumugam, T. V., Magnus, T., Huber, S., Gelderblom, M., Drummond, G. R., Sobey, C. G. & Kim, H. A., 20 Sep 2018, In : JCI Insight. 3, 18, 16 p., e121560.

Research output: Contribution to journalArticleResearchpeer-review

Multitasking: A challenge for the kidney

Ngo, J. P. & Evans, R. G., 16 Apr 2018, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 314, 4, p. R540-R541 2 p.

Research output: Contribution to journalArticleOtherpeer-review

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Proteomic Identification of Interferon-Induced Proteins with Tetratricopeptide Repeats as Markers of M1 Macrophage Polarization

Huang, C., Lewis, C., Borg, N. A., Canals, M., Diep, H., Drummond, G. R., Goode, R. J., Schittenhelm, R. B., Vinh, A., Zhu, M., Kemp-Harper, B., Kleifeld, O. & Stone, M. J., 6 Apr 2018, In : Journal of Proteome Research. 17, 4, p. 1485-1499 15 p.

Research output: Contribution to journalArticleResearchpeer-review

Renal Denervation: A Treatment for Hypertension and Chronic Kidney Disease

Singh, R. R. & Denton, K. M., 1 Sep 2018, In : Hypertension. 72, 3, p. 528-536 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Three-dimensional morphometric analysis of the renal vasculature

Khan, Z., Ngo, J. P., Le, B., Evans, R. G., Pearson, J. T., Gardiner, B. S. & Smith, D. W., 1 May 2018, In : American Journal of Physiology - Renal Physiology. 314, 5, p. F715-F725 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Urinary hypoxia: An intraoperative marker of risk of cardiac surgery-associated acute kidney injury

Zhu, M. Z. L., Martin, A., Cochrane, A. D., Smith, J. A., Thrift, A. G., Harrop, G. K., Ngo, J. P. & Evans, R. G., Dec 2018, In : Nephrology Dialysis Transplantation. 33, 12, p. 2191-2201 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Urinary Oxygenation as a Surrogate Measure of Medullary Oxygenation during Angiotensin II Therapy in Septic Acute Kidney Injury

Lankadeva, Y. R., Kosaka, J., Evans, R. G., Bellomo, R. & May, C. N., 1 Jan 2018, In : Critical Care Medicine. 46, 1, p. e41-e48 8 p.

Research output: Contribution to journalArticleResearchpeer-review

Vitamin D3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke

Evans, M. A., Kim, H. A., Ling, Y. H., Uong, S., Vinh, A., De Silva, T. M., Arumugam, T. V., Clarkson, A. N., Zosky, G. R., Drummond, G. R., Broughton, B. R. S. & Sobey, C. G., 1 Mar 2018, In : NeuroMolecular Medicine. 20, 1, p. 147-159 13 p.

Research output: Contribution to journalArticleResearchpeer-review

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2017

Anti-fibrotic potential of AT2 receptor agonists

Wang, Y., Del Borgo, M., Lee, H. W., Baraldi, D., Hirmiz, B., Gaspari, T. A., Denton, K. M., Aguilar, M-I., Samuel, C. S. & Widdop, R. E., 31 Aug 2017, In : Frontiers in Pharmacology. 8, 7 p., 564.

Research output: Contribution to journalArticleOtherpeer-review

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Combining new tools to assess renal function and morphology: A holistic approach to study the effects of aging and a congenital nephron deficit

Geraci, S., Chacon-Caldera, J., Cullen-McEwen, L., Schad, L. R., Sticht, C., Puelles, V. G., Bertram, J. F. & Gretz, N., 1 Sep 2017, In : American Journal of Physiology - Renal Physiology. 313, 3, p. F576-F584 9 p.

Research output: Contribution to journalArticleResearchpeer-review

Epigenetic modifications to H3K9 in renal tubulointerstitial cells after unilateral ureteric obstruction and TGF-β1 stimulation

Hewitson, T. D., Holt, S. G., Tan, S-J., Wigg, B., Samuel, C. S. & Smith, E. R., 29 May 2017, In : Frontiers in Pharmacology. 8, 15 p., 307.

Research output: Contribution to journalArticleResearchpeer-review

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Micro-computed tomographic analysis of the radial geometry of intrarenal artery-vein pairs in rats and rabbits: Comparison with light microscopy

Ngo, J. P., Le, B., Khan, Z., Kett, M. M., Gardiner, B. S., Smith, D. W., Melhem, M. M., Maksimenko, A., Pearson, J. T. & Evans, R. G., Dec 2017, In : Clinical and Experimental Pharmacology and Physiology. 44, 12, p. 1241-1253 13 p.

Research output: Contribution to journalArticleResearchpeer-review

Pressor response to angiotensin II is enhanced in aged mice and associated with inflammation, vasoconstriction and oxidative stress

Dinh, Q. N., Drummond, G. R., Kemp-Harper, B. K., Diep, H., De Silva, T. M., Kim, H. A., Vinh, A., Robertson, A. A. B., Cooper, M. A., Mansell, A., Chrissobolis, S. & Sobey, C. G., 28 Jun 2017, In : Aging. 9, 6, p. 1595-1605 11 p.

Research output: Contribution to journalArticleResearchpeer-review

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Relaxin contributes to the regulation of arterial pressure in adult female mice

Colafella, K. M. M., Samuel, C. S. & Denton, K. M., 28 Nov 2017, In : Clinical Science. 131, 23, p. 2795-2805 11 p.

Research output: Contribution to journalArticleResearchpeer-review

Renal denervation promotes atherosclerosis in hypertensive apolipoprotein E-Deficient mice infused with angiotensin II

Wang, Y., Dinh, T. N., Nield, A., Krishna, S. M., Denton, K. & Golledge, J., 13 Apr 2017, In : Frontiers in Physiology. 8, 9 p., 215.

Research output: Contribution to journalArticleResearchpeer-review

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Zinc is a critical regulator of placental morphogenesis and maternal hemodynamics during pregnancy in mice

Wilson, R. L., Leemaqz, S. Y., Goh, Z., McAninch, D., Jankovic-Karasoulos, T., Leghi, G. E., Phillips, J. A., Colafella, K. M., Tran, C., O'Leary, S., Buckberry, S., Pederson, S., Robertson, S. A., Bianco-Miotto, T. & Roberts, C. T., 9 Nov 2017, In : Scientific Reports. 7, 1, 14 p., 15137.

Research output: Contribution to journalArticleResearchpeer-review

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2016

Low dose dietary nitrate improves endothelial dysfunction and plaque stability in the ApoE−/− mouse fed a high fat diet

Bakker, J. R., Bondonno, N. P., Gaspari, T. A., Kemp-Harper, B. K., McCashney, A. J., Hodgson, J. M., Croft, K. D. & Ward, N. C., 1 Oct 2016, In : Free Radical Biology and Medicine. 99, p. 189-198 10 p.

Research output: Contribution to journalArticleResearchpeer-review